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Factors associated with heterochronic gastric cancer development post-endoscopic mucosal dissection in early gastric cancer patients

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World Journal of Gastrointestinal Oncology 2023年第9期15卷 1644-1652页

作者： Bing Xie Yun Xia Xia Wang Yan Xiong shao-Bo Chen Jie Zhang Wei-Wei He Department of Spleen and Stomach Nanjing Pu Kou District Hospital of Traditional Chinese MedicinePukou 210000Jiangsu ProvinceChina Science and Education Section Nanjing Pu Kou District Hospital of Traditional Chinese MedicinePukou 210000Jiangsu ProvinceChina Anesthesiology Department Nanjing Pu Kou District Hospital of Traditional Chinese MedicinePukou 210000Jiangsu ProvinceChina Department of Oncology Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese MedicineNanjing 210022Jiangsu ProvinceChina

BACKGROUND Endoscopic mucosal resection is an innovative method for treating early gastric cancer and has been widely used in clinical *** To analyze the factors associated with the development of heterochronic gastric cancer in patients with early gastric cancer who had undergone endoscopic mucosal dissection(EMD).METHODS A cohort of patients with early gastric cancer treated using EMD was retrospectively analyzed,and patients who developed heterochronic gastric cancer after the surgery were compared with those who did *** effects of patient age,sex,tumor size,pathological type,and surgical technique on the development of heterochronic gastric cancer were assessed using statistical *** Of the 300 patients with early gastric cancer,150 patients developed heterochronic gastric cancer after *** analysis revealed that patient age(P value=XX),sex(P value=XX),tumor size(P value=XX),pathological type(P value=XX),and surgical technique(P value=XX)were significantly associated with the occurrence of heterochronic gastric *** Age,sex,tumor size,pathological type,and surgical technique are key factors influencing the occurrence of heterochronic gastric cancer after EMD in patients with early gastric *** address these factors,postoperative follow-up and management should be strengthened to improve the prognosis and survival rate of patients.

关键词： Early gastric cancer Endoscopic mucosal dissection Heterochronic gastric cancer Associated factors Statistical analysis

Tease out the future: How tea research might enable crop breeding for acid soil tolerance

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Plant Communications 2021年第3期2卷 27-37页

作者： Zhong Jie Ding Yuan Zhi Shi Gui Xin Li Nicholas P.Harberd shao Jian Zheng State Key Laboratory of Plant Physiology and Biochemistry College of Life SciencesZhejiang UniversityHangzhou 310058China Tea Research Institute Chinese Academy of Agriculture SciencesKey Laboratory for Tea Plant Biology and Resource UtilizationMinistry of Agriculture and Rural AffairsHangzhou 310008China College of Agronomy and Biotechnology Zhejiang UniversityHangzhou 310058China Department of Plant Sciences University of OxfordOxford OX13RBUK

Unlike most crops,in which soil acidity severely limits productivity,tea(Camellia sinensis)actually prefers acid soils(pH 4.0–5.5).Specifically,tea is very tolerant of acidity-promoted aluminum(Al)toxicity,a major factor that limits the yield of most other crops,and it even requires Al for optimum *** tea Al tolerance and Al-stimulatory mechanisms could therefore be fundamental for the future development of crops adapted to acid ***,we summarize the Al-tolerance mechanisms of tea plants,propose possible mechanistic explanations for the stimulation of tea growth by Al based on recent research,and put forward ideas for future crop breeding for acid soils.

关键词： aluminum acid soil tea Camellia sinensis breeding

Kinetics of the formation of N2O in the catalytic oxidation of NH3 on Pt-Rh filament

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Acta Chimica Sinica(English Edition) 1985年第1期3卷 7-13页

作者： HU Zu-shao QIN Qi-Zong Laser Chemistry Laboratory,Fudan University,Shanghai Laser Chemistry Laboratory Fudan University Shanghai

The kinetics of the reactions involving the formation of N2O in the catalytic oxidationof NH3 have been studied over polycrystalline Pt-10% Rh filament in a static system,using a Fou-rier transform infrared spectrometer to monitor the partial pressures of NH3 and *** soleformation of N2O proceeds over the filament temperatures range of 250～350℃.The reaction rateis of first order in NH3 pressure and half order in O2 pressure,and the rate equation can be writtenas v=kapp·PNH3·PO21/*** apparent activation energy of the N2O formation reaction fromthe temperature coefficient of the rate constants is found to be 25 kcal/*** interpretation ofthese results in terms of Eley-Rideal type mechanism has been *** rate-controllingstep might be the reaction between gaseous ammonia molecules and the chemisorped oxygen atomson the surface.

关键词： Kinetics of the formation of N2O in the catalytic oxidation of NH3 on Pt-Rh filament Pt Rh NH

Photoinduced palladium-catalyzed 1,3-diene-selective fluoroalkylamination compounds as potential bactericidal agent against Xanthomonas oryzae ***

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Chinese Chemical Letters 2024年第1期35卷 401-405页

作者： Yu Shi Zhao-Sheng Zhang Jiang shao Chen Fu Lan-Tu Xiong Zhao-Dong Li Zi-Ning Cui National Key Laboratory of Green Pesticide Integrative Microbiology Research CentreGuangdong Province Key Laboratory of Microbial Signals and Disease ControlCollege of Plant ProtectionSouth China Agricultural UniversityGuangzhou 510642China Henry Fok School of Biology and Agriculture Shaoguan UniversityShaoguan 512005China College of Materials and Energy South China Agricultural UniversityGuangzhou 510642China

A series of photoinduced palladium-catalyzed 1,3-diene-selective fluoroalkylamination derivatives was rationally synthesized based on diversity-oriented synthesis via cross coupling of 1,3-dienes,amines and fluoroalkyl *** reaction featured good function group tolerance and a broad substrate scope,which could be extended to the late-stage modification of bioactive *** activity of all the compounds against Xanthomonas oryzae ***(Xoo)was *** them,compound E14 showed significant activity against Xanthomonas oryzae ***(Xoo)with half maximal effective concentration(EC50)value of 6.61μmol/*** pot experiments,the results showed that E14 could control rice bacterial blight with protective and curative efficiencies of 37.5%and 63.2%at 200μg/mL,***,a plausible mechanism for antibacterial behavior of E14 was proposed by electron microscopy,flow cytometry,reactive oxygen species detection,and biofilm *** current work,it can promote the development of photoinduced palladium-catalyzed 1,3-diene-selective fluoroalkyl amination compounds as prospective antibacterial agent bearing an intriguing mode of action.

关键词： 1,3-Diene-selective fluoroalkylamination derivatives Xanthomonas oryzae pv.oryzae Antibacterial activity Electron microscopy Reactive oxygen Flow cytometry

Simple fabrication of superhydrophobic PLA with honeycomb-like structures for high-efficiency oil-water separation

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Chinese Chemical Letters 2020年第2期31卷 365-368页

作者： Xiaolong Wang Yamin Pan Huan Yuan Meng Su Chunguang shao Chuntai Liu Zhanhu Guo Changyu Shen Xianhu Liu College of Materials Science and Engineering and National Engineering Research Center for Advanced Polymer Processing Technology Zhengzhou UniversityZhengzhou 450002China Key Laboratory of Advanced Material Processing&Mold(Zhengzhou University) Ministry of EducationZhengzhou 450002China Technology Development Center for Polymer Processing Engineering Guangdong Colleges and UniversitiesGuangdong Industry Technical CollegeGuangzhou 510641China Integrated Composites Laboratory(ICL) Department of Chemical&Biomolecular EngineeringUniversity of TennesseeKnoxvilleTN 37996United States

Polylactic acid(PLA) is one of the most suitable candidates for environmental pollution treatment because of its biodegradability which will not cause secondary pollution to the environment after ***,there is still a lack of a green and facile way to prepare PLA oil-water separation *** this work,a water-assisted thermally induced phase separation method for the preparation of superhydrophobic PLA oil-water separation material with honeycomb-like structures is *** PLA material shows great ability in application and could adsorb 27.3 times oil to its own *** addition,it could also be applicated as a filter with excellent efficiency(50.9 m^3 m^(-2) h^(-1)).

关键词： Biodegradability PLA Phase separation Oil-water separation Superhydrophobicity

Neutrophil extracellular traps contribute to myofibroblast differentiation and scar hyperplasia through the Toll-like receptor 9/nuclear factor Kappa-B/interleukin-6 pathway

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Burns & Trauma 2022年第1期10卷 116-128页

作者： Yiming shao Zaiwen Guo Yunxi Yang Lu Liu Jiamin Huang Yi Chen Linbin Li Bingwei Sun Department of Burns and Plastic Surgery Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou 215002Jiangsu ProvinceChina

Background:Inflammation is an important factor in pathological *** role of neutrophils,one of the most important inflammatory cells,in scar hyperplasia remains *** purpose of this article is to study the correlation between neutrophil extracellular traps(NETs)and scar hyperplasia and identify a new target for inhibiting scar ***:Neutrophils were isolated from human peripheral blood by magnetic-bead *** in plasma and scars were detected by enzyme-linked immunosorbent assays(ELISAs),immunofluorescence and flow *** was used to assess neutrophil(CD66B)infiltration in hypertrophic *** observe the entry of NETs into fibroblasts we used immunofluorescence and flow ***:We found that peripheral blood neutrophils in patients with hypertrophic scars were more likely to form NETs(p0.05].However,inhibiting the production of NETs or degrading DNA reduced the differentiation of fibroblasts *** vitro,NETs were found to be mediated by Toll-like receptor 9(TLR-9)in fibroblasts and further phosphorylated nuclear factor Kappa-B(NF-κB).We found that IL-6,which is downstream of NF-κB,was increased in ***,IL-6 uses autocrine and paracrine signaling to promote differentiation and ***:Our experiments found that NETs activate fibroblasts through the TLR-9/NF-κB/IL-6 pathway,thereby providing a new target for regulating hypertrophic scars.

关键词： Neutrophil extracellular traps Hypertrophic scar Toll-like receptor 9 Fibroblast Inflammation Differentiation Nuclear factor Kappa-B Interleukin-6

Study on Corrosion Resistance of Ni-W-P Coating in Hypersaline Brine

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Acta Geologica Sinica(English Edition) 2014年第S1期88卷 369-370页

作者： shao Qianqian ZHANG Xin CUI Zhaojie TAN Xianfeng School of Environmental Science and Engineering Shandong University Shandong Provincial Lubei Geo-engineering Exploration Institute

Brine resource is rich in China,but its exploitation has been a *** brine will corrode equipment and materials seriously during the brine exploitation and *** corrosion problem can cause great

关键词： Ni-W-P coating corrosion resistance hypersaline water.

Synthesis and insecticidal evaluation of tetrahydroimidazo[1,2-a]pyridin-5(1H)-one derivatives

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Chinese Chemical Letters 2016年第1期27卷 7-10页

作者： Xuan-Qi Liu Ya-Qin Liu Xu-Sheng shao Zhi-Ping Xu Xiao-Yong Xu Zhong Li Shanghai Key Lab of Chemistry Biology School of Pharmacy East China University of Science and Technology Shanghai 200237 China Shanghai Collaborative Innovation Center for Biomanufacturing Technology Shanghai 200237 China

A series of novel tetrahydroimidazo[1,2-a]pyridine-5（1H）-one derivatives containing a electronegative pharmacophore（=CNO_2） were synthesized via practical aza-ene reaction and characterized by ~1H NMR,^（13）C NMR,^（19）F NMR and HRMS. Preliminary bioassays showed that some of the target compounds exhibited good insecticidal activity against brown planthopper（Nilaparvata lugens） and cowpea aphids（Aphis craccivora） at 500 mg L^（-1）. Among them, compound 11 h was active against brown planthopper at100 mg L^（-1）. The insecticidal activities varied significantly depending on the types and patterns of the substituents, which provided guidance for further investigation on structure modifications.

关键词： Neonicotinoids Tetrahydroimidazo[1,2-a]pyridin-5(1H) one Configuration Insecticidal activity

On general Bernstein and Nikol’ski type inequalities

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Applied Mathematics(A Journal of Chinese Universities) 2010年第1期25卷 35-42页

作者： CAO Fei-long LIN shao-bo ZHANG Bao-lin Department of Mathematics China Jiliang University Hangzhou 310018 China

The goal of this paper is to establish the relations between general Bernstein and Nikol＇skii type inequalities under some weak conditions. From these relations some known classical inequalities are implied. Also, a ... 详细信息

关键词： Bernstein inequality Nikol'skii inequality Markov inequality.