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Association between endogenous cortisol level and the risk of central serous chorioretinopathy:a Meta-analysis

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International Journal of Ophthalmology(English edition) 2018年第2期11卷 296-300页

作者： Zhi-Qiao Liang Lyu-zhen Huang Jin-Feng Qu ming-wei Zhao Department of Ophthalmology Peking University People's HospitalBeijing 100044China Eye Diseases and Optometry Institute Beijing 100044China Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases Beijing 100044China College of Optometry Peking University Health Science CenterBeijing 100044China

AIM： To assess the association between endogenous cortisol level and the risk of central serous chorioretinopathy（CSC）.METHODS： Case-control studies were systematically searched on PubM ed, Embase, Cochrane, China National Knowledge Infrastructure（CNKI） for publishes between January 1990 and July 2017 to assess the association between endogenous cortisol level and CSC. The main endpoints were serum cortisol level at 8 a.m. and 24-hour urine 17-hydroxysteroids level. We assessed pooled data using a random-effects ***： Of 86 identified studies, 5 were eligible included in our analysis. The 5 studies included a total of 315 participants, of whom 187 had CSC. Statistically significant association was observed between serum cortisol level（summary SMD=0.77, 95%CI=0.55-0.99）, 24-hour urine 17-hydroxysteroids level（summary SMD=0.95, 95%CI=0.61-1.30）, and the risk of ***： Endogenous cortisol level is associated with an increased risk of CSC. Combined treatment targeting the serum cortisol level at 8 a.m. and 24-hour urine 17-hydroxysteroids level can be a potential preventive strategy for individuals who are at risk of CSC and therapeutic strategy for patients with CSC.

关键词： endogenous cortisol central serous chorioretinopathy serum cortisol 24-hour urine 17-hydroxysteroids Meta-analysis

Rational design and structural regulation of near-infrared silver chalcogenide quantum dots

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维普期刊数据库

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Nano Research 2024年第12期17卷 10585-10606页

作者： zhen-Ya Liu wei Zhao Li-ming Chen Yan-Yan Chen Zhi-Gang Wang An-An Liu Dai-Wen Pang College of Chemistry School of Medicine and Frontiers Science Center for Cell ResponsesFrontiers Science Centre for New Organic MatterTianjin Key Laboratory of Biosensing and Molecular RecognitionResearch Centre for Analytical SciencesNankai UniversityTianjin 300071China School of Chemical and Environmental Engineering Yancheng Teachers UniversityYancheng 224002China Haihe Laboratory of Sustainable Chemical Transformations Tianjin 300192China

Silver chalcogenides(Ag_(2)E;E=S,Se,or Te)quantum dots(QDs)have emerged as promising candidates for near-infrared(NIR)***,their narrow bandgap and small exciton Bohr radius render the optical properties of Ag_(2)E QDs highly sensitive to surface and size ***,the propensity for the formation of silver impurities and their low solubility product constants pose challenges in their controllable *** advancements have deepened our understanding of the relationship between the multi-hierarchical structure of Ag_(2)E QDs and their optical *** rational design and precise structural regulation,the performance of Ag_(2)E QDs has been significantly enhanced across various *** review provides a comprehensive overview of historical and current progress in the synthesis and structural regulation of Ag_(2)E QDs,encompassing aspects such as size control,crystal structure engineering,and surface/interface ***,it discusses outstanding challenges and potential opportunities in this *** aim of this review is to promote the custom synthesis of Ag_(2)E QDs for applications in biological imaging,and optoelectronics applications.

关键词： silver chalcogenides structural regulation size control crystal engineering surface and interface regulation

Optical Properties of BDK-Doped Highly Photosensitive Sol-Gel Hybrid Film

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Chinese Physics Letters 2011年第8期28卷 115-118页

作者： XU ming SHEN wei-Dong ZHANG Yue-Guang zhen Hong-Yu LIU Xu State Key Laboratory of Modern Optical Instrumentation Zhejiang UniversityHangzhou 310027

A new organic-inorganic hybrid material doped with BDK that exhibits a large photo-induced change in optical properties is prepared by the sol-gel *** photosensitivity of the film under ultraviolet irradiation is investigated with various exposure *** increase in refractive index from 1.558 to 1.592 atλ=550 nm is observed together with a 57.3%expansion in physical *** film's optical thickness exhibits an exponential change with the irradiation *** photo-decomposition of BDK organic groups confirmed by the infrared absorption spectrum contributes to the photosensitive mechanism.A first example of photo-patterning is finally presented by direct light writing.

关键词： film ultraviolet finally

Size distribution of the secondary organic aerosol particles from the photooxidation of toluene

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Journal of Environmental Sciences 2005年第6期17卷 912-916页

作者： HAO Li-qing WANG zhen-ya HUANG ming-qiang PEI Shi-xin YANG Yong ZHANG wei-jun Laboratory of Environmental Spectroscopy Anhui Institute of Optics and Fine Mechanics Chinese Academy of Sciences Hefei 230031 China

In a smog chamber, the photooxidation of toluene was initiated by hydroxyl radical （OH.） under different experimental conditions. The size distribution of secondary organic aerosol（SOA） particles from the above reaction was measured using aerodynamic particle sizer spectrometer. It was found from our experimental results that the number of SOA particles increased with increasing the concentration of toluene. As the reaction time prolonged, the sum of SOA particles was also increased. After a reaction time of 130 min, the concentration of secondary organic aerosol particles would be kept constant at 2300 particles/cm^3. Increasing illumination power of blacklamps could significantly induce a higher concentration of secondary organic aerosol particle. The density of SOA particles would also be increased with increasing concentration of CH30NO, however, it would be decreased as soon as the concentration of CH30NO was larger than 225.2 ppm. Nitrogen oxide with initial concentration higher than 30. 1 ppm was also found to have little effect on the formation of secondary organic aerosol.

关键词： toluene hydroxyl radical secondary organic aerosol smog chamber

To Be,Or Not To Be:The Calculated Politics of Acupuncture in JAMA

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Chinese Journal of Integrative Medicine 2017年第11期23卷 803-808页

作者： GONG Chang-zhen LIU wei American Academy of Acupuncture and Oriental Medicine RosevilleMN(55113)United States

Ten acupuncture-related articles were published in The Journal of the American Medical Association（JAMA） between 1998 and 2017. Five studies showed positive results in terms of the effectiveness of acupuncture/Chinese medicine（CM）; five studies showed negative results. This article summarizes the acupuncturerelated clinical trials published over the last 20 years in JAMA, and addresses what seems to be a fundamental ambivalence in Western medical journals regarding the scientific validity of acupuncture/CM. As yet there has been no consensus on the role of acupuncture in healthcare in Western countries. This is hardly surprising, considering the conflicting evidence found in published studies. Skepticism regarding acupuncture/CM is largely grounded in the fact that an accurate model for assessing the true clinical effects of acupuncture has yet to be created. This article discusses some of the pitfalls which result from applying Western-based scientific principles to CM, and suggests that in many cases, ＂negative＂ studies have been misinterpreted. The clinical experience of acupuncture practitioners is often in direct conflict with many of the negative conclusions published in journals. We are in need of an accurate model for sham and placebo treatments, and must analyze all published studies for design flaws and faulty conclusions.

关键词： Chinese medicine acupuncture Western medical journals study design

Signal perception during plant-bacteria interactions: from chemicals to physical signals

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Science China(Life Sciences) 2020年第2期63卷 305-307页

作者： Bao-zhen Ren wei Qian State Key Laboratory of Plant Genomics Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China College of Biological Sciences University of Chinese Academy of SciencesBeijing 100049China Center for Excellence of Biotic Interactions Chinese Academy of SciencesBeijing 100101China College of Advanced Agricultural Sciences University of Chinese Academy of SciencesBeijing 100049China

During interactions between host plants and microbes, discrimination between "self" and "nonself" is at the center of many biological relationships and determines the success of infection by microbial pathogens or imm... 详细信息

关键词： Signal immunity signals

Two Evidence-Based Acupuncture Models

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Chinese Journal of Integrative Medicine 2020年第1期26卷 3-7页

作者： GONG Chang-zhen LIU wei American Academy of Acupuncture and Oriental Medicine

Modern clinical trials have produced controversial data interpretation which refutes conventional standard teachings and practices. Acupuncture scholars and practitioners have been stimulated to scrutinize these trials and analyze conventional practices. This paper presents two acupuncture models which address these issues. One rationalizes the clinical trial results with newer understanding of acupuncture points and techniques, while the other reconciles these results with rediscovered techniques of palpating points and performing needling. These two models indicate that acupuncture is in transition from classical model to evidence-based models.

关键词： acupuncture model evidence-based LI Yong-ming’s Balloon model LENG San-hua’s C-Nerve Network Counter-Stimulation model

Failure mechanism and control countermeasures of surrounding rock at deep large section chamber intersection in the Wanfu Coal Mine

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Journal of Mountain Science 2023年第7期20卷 2058-2075页

作者： SUN Xiao-ming QI zhen-min ZHANG Yong MIAO Cheng-yu ZHAO Cheng-wei HE Man-chao State Key Laboratory for GeoMechanics and Deep Underground Engineering China University of Mining&Technology BeijingBeijing 100083China School of Mechanics and Civil Engineering China University of Mining&Technology-BeijingBeijing 100083China Institute of Rock and Soil Mechanics Chinese Academy of SciencesWuhan 430060China

In order to solve the problem of large deformation at the intersection of deep large section soft rock roadway,this paper takes the intersection of kilometer-deep roadway in the Wanfu Coal Mine as an engineering example and applies Negative Poisson’s Ratio(NPR)steel anchor cable in roadway support for the first *** combining numerical simulation indoor test,theoretical analysis and field test,the deformation mechanism of surrounding rock at the intersection of deep-buried roadway was analyzed,and the control strategy with micro NPR steel anchor cable as the core was put *** numerical simulation,the numerical analysis model of roadway intersection with different intersection angles and excavation sequence was constructed,and the impact of two key variables of rake angle and excavation sequence on the stability of surrounding rock at roadway intersection was *** optimal dip angle is 90°and the optimal excavation sequence was determined as pump house-pump house *** mechanical properties of the micro-NPR steel anchor cable were studied through the static tensile test in the *** results showed that the micro-NPR steel anchor cable showed high constant resistance,uniform tensile,no yield platform,and no obvious necking phenomenon during *** theoretical derivation,it was calculated that the vertical stress of roadway intersection is 45 MPa,and the bearing capacity of superposed arch composed of micro NPR steel anchor cable is 1257 kN,which is enough to guarantee the overall stability of *** application test and monitoring were carried out on site,and it was verified that the combined support strategy of short and long micro NPR steel anchor cable has a good control effect on large deformation of surrounding rock at intersection,which provides a new support material and support means for the safety and stabilization control of surrounding rock at intersection.

关键词： Mountain tunnel Composite lining Surrounding rock grade Force variation Primary support Secondary lining

Learning synergies based in-hand manipulation with reward shaping

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CAAI Transactions on Intelligence Technology 2020年第3期5卷 141-149页

作者： zhen Deng Jian wei Zhang TAMS Group InformaticsUniversity of HamburgHamburg D-22527Germany

In-hand manipulation is a fundamental ability for multi-fingered robotic hands that interact with their *** to the high dimensionality of robotic hands and intermittent contact dynamics,effectively programming a robotic hand for in-hand manipulations is still a challenging *** address this challenge,this work employs deep reinforcement learning(DRL)algorithm to learn in-hand manipulations for multi-fingered robotic hands.A reward-shaping method is proposed to assist the learning of in-hand *** synergy of robotic hand postures is analysed to build a low-dimensional hand posture *** additional rewards are designed based on both the analysis of hand synergies and its learning *** two additional rewards cooperating with an extrinsic reward are used to assist the in-hand manipulation *** value functions are trained jointly with respect to their reward *** they cooperate to optimise a control policy for in-hand *** reward shaping not only improves the exploration efficiency of the DRL algorithm but also provides a way to incorporate domain *** performance of the proposed learning method is evaluated with object rotation *** results demonstrated that the proposed learning method enables multi-fingered robotic hands to learn in-hand manipulation effectively.

关键词： manipulation policy jointly