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Synthesis of Novel Chiral Diol ligands for the Enantioselective Reactions

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Chinese Chemical Letters 2001年第6期12卷 489-490页

作者： ming xia li Yan ming WANG Ru Ru CHEN Research Institute of Elemento-Organic Chemistry Nankai UniversityTianjin 300071 Pittsburgh University Medical Center PittsburghPA 15213U.S.A

A series of novel enantiomerically pure diols were synthesized from D-erythorbic acid in three steps, and the absolute configuration of one of them 4a has been confirmed by X-ray analysis.

关键词： Enantiomerically pure chiral diol ligands X-ray analysis

Some Properties of β-wordlength Pattern for Four-level Designs

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Acta Mathematica Sinica,English Series 2015年第7期31卷 1163-1170页

作者： Wei Wei SHENG xia ming li Yu TANG School of Mathematical Sciences Soochow University

Fractional factorial designs have played a prominent role in the theory and practice of experimental design. For designs with qualitative factors under an ANOVA model, the minimum aber-ration criterion has been frequently used; however, for designs with quantitative factors, a polynomial regression model is often established, thus the β-wordlength pattern can be employed to compare different fractional factorial designs. Although the β-wordlength pattern was introduced in 2004, its properties have not been investigated extensively. In this paper, we will present some properties of β-wordlength pattern for four-level designs. These properties can help find better designs with quan- titative factors.

关键词： β-wordlength pattern four-level fractional factorial design

Some Numerical Quadrature Schemes of a Non-conforming Quadrilateral Finite Element

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Acta Mathematicae Applicatae Sinica 2012年第1期28卷 117-126页

作者： xiao-fei GUAN ming-xia li Shao-chun CHEN Department of Mathematics Tongji UniversityShanghai 200092China School of Information Engineering China University of Ceosciences(Beijing)Beijing 100083China Department of Mathematics Zhengzhou UniversityZhengzhou 450052China

Numerical quadrature schemes of a non-conforming finite element method for general second order elliptic problems in two dimensional （2-D） and three dimensional （3-D） space are discussed in this paper. We present and analyze some optimal numerical quadrature schemes. One of the schemes contains only three sampling points, which greatly improves the efficiency of numerical computations. The optimal error estimates are derived by using some traditional approaches and techniques. Lastly, some numerical results are provided to verify our theoretical analysis.

关键词： numerical integration non-conforming quadrilateral finite element optimal error estimate

Experimental investigation of an adjustable ejector for CO_2 heat pump water heaters

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第11期10卷 1678-1682页

作者： Guang-ming CHEN li-xia liANG li-ming TANG xiao-xiao XU Zhi-jiang ZHU Qi CHEN State Key Laboratory of Clean Energy Utilization Institute of Refrigeration and Cryogenics Zhejiang University Hangzhou 310027 China

An adjustable ejector expansion device for a CO2 heat pump water heater (HPWP) is proposed to improve the system performance. It has been designed to investigate experimentally the effects of the motive nozzle throat area of the ejector, entrained flow pressure, back pressure and primary flow pressure on the entrainment ratio. Experiments based on different motive nozzle throat areas were conducted and the results of the prototype ejector using CO2 as working fluid are presented. The results show that an adjustable ejector can achieve high performance and work well in a wide range of working conditions.

关键词： Adjustable elector System nerformance CO2 heat oumo water heater (HPWH) Entrainment ratio

Scattering of a single photon in a one-dimensional coupled resonator waveguide with a Λ-type emitter assisted by an additional cavity

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Chinese Physics B 2018年第5期27卷 241-244页

作者： ming-xia li Jie Yang Gong-Wei lin Yue-Ping Niu Shang-Qing Gong East China University of Science and Technology Shanghai 200237 China

We analyze the transport property of a single photon in a one-dimensional coupled resonator waveguide coupled with a Λ-type emitter assisted by an additional cavity. The reflection and transmission coefficients of the inserted photon are obtained by the stationary theory. It is shown that the polarization state of the inserted photon can be converted with high efficiency. This study may inspire single-photon devices for scalable quantum memory.

关键词： one-dimensional waveguide photon scattering quantum memory

Down-regulation of PTEN expression due to loss of promoter activity in human hepatocellular carcinoma cell lines

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World Journal of Gastroenterology 2005年第29期11卷 4472-4477页

作者： Dong-Zhu Ma Zhen Xu Yu-Long liang Jian-ming Su Zeng-xia li Wen Zhang li-Ying Wang Xi-liang Zha Ministry of Health Key Laboratory of Glycocojugate Research Department of Biochemistry and Molecular Biology Shanghai Medical College Fudan University Shanghai 200032 China

AIM: To investigate the regulation of phosphatase and tensin homolog deleted on chromosome ten (PTEN) gene expression in human hepatocellular carcinoma (HCC) cell ***: The mRNA and protein levels of PTEN were detected by Northern blot and Western blot in HCC cell lines, respectively. Plasmids containing different fragments of PTEN promoter with Luciferase reporter were constructed and transiently transfected into HCC cell lines to study the promoter activity. DNA analysis and RT-PCR were performed to detect the mutation of PTEN promoter and PTEN ***: Either protein or mRNA levels of PTEN in L02 cells (as a control) were significantly higher than that in HCC cell lines. The profile of PTEN promoter activity in 8 cell lines was closely correlated with levels of PTEN mRNA and PTEN protein. Furthermore, the sequence analysis of 8 cells lines showed no mutation in the region of PTEN promoter and ***: PTEN expression is down-regulated in HCC cell lines probably due to loss of activity of PTEN promoter.

关键词： Phosphatase Tensin homolog Hepatocellular carcinoma

The Number of Positive Pelvic Lymph Nodes and Multiple Groups of Pelvic Lymph Node Metastasis Influence Prognosis in Stage ⅠA-ⅡB Cervical Squamous Cell Carcinoma

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Chinese Medical Journal 2015年第15期128卷 2084-2089页

作者： Yu liu li-Jon Zhao ming-Zho li ming-xia li Jian-liu Wang li-Hui Wei Department of Obstetrics and Gynecology Peking University People's Hospital Beijing 100044 China

Background：Pelvic lymph node metastasis （LNM） is an important prognostic factor in cervical *** squamous cell carcinoma accounts for approximately 75-80% of all cervical *** of the effects of the number of positive lymph nodes （LNs）,unilateral vcrsus bilateral pelvic LNM and a single group versus multiple groups of pelvic LNM on survival and recurrence of cervical squamous cell carcinoma are still *** study aimed to analyze the effects of the number of positive pelvic LNs and a single group versus multiple groups of pelvic LNM on survival and ***：We performed a retrospective review of 296 patients diagnosed with Stage ⅠA-ⅡB cervical squamous cell carcinoma who received extensive/sub-extensive hysterectomy with pelvic lymphadenectomy/pelvic LN sampling at Peking University People＇s Hospital from November 2004 to July *** clinicopathological variables were evaluated as risk factors for pelvic LNM：Age at diagnosis,gravidity,clinical stage,histological grade,tumor diameter,lymph-vascular space involvement （LVSI）,depth of cervical stromal invasion,uterine invasion,parametrial invasion,and neoadjuvant ***：The incidence of pelvic LNM was 20.27% （60/296 cases）.Pelvic LNM （P =0.00） was significantly correlated with *** LNM （P =0.00）,the number of positive pelvic LNs （P =0.04） and a single group versus multiple groups of pelvic LNM （P =0.03）had a significant influence on *** analysis revealed that LVSI （P =0.00）,depth of cervical stromal invasion （P =0.00）and parametrial invasion （P =0.03） were independently associated with pelvic ***：Patients with pelvic LNM had a higher recurrence rate and poor survival ***,more than 2 positive pelvic LNs and multiple groups of pelvic LNM appeared to identify patients with worse survival outcomes in node-positive ⅠA-ⅡB cervical squamous cell ***,parametrial invasion,and depth of cervical stromal invas

关键词： Cervical Squamous Cell Carcinoma Pelvic Lymph Node Metastasis Prognosis

Stroke-like Migraine Attacks after Radiation Therapy Syndrome

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Chinese Medical Journal 2015年第15期128卷 2097-2101页

作者： Qian Zheng li Yang li-ming Tan li-xia Qin Chun-Yu Wang Hai-Nan Zhang Department of Neurology Second Xiangya Hospital Central South University Changsha Hunan 410011 China

Objective：To summarize the clinical presentation,pathogenesis,neuroimaging,treatment,and outcome of stroke-like migraine attacks after radiation therapy （SMART） syndrome,and to propose diagnostic criteria for this *** Sources：We searched the PubMed database for articles in English published from 1995 to 2015 using the terms of ＂stroke-like AND migraine AND radiation.＂ Reference lists of the identified articles and reviews were used to retrieve additional *** Selection：Data and articles related to late-onset effects of cerebral radiation were selected and ***：SMART is a rare condition that involves complex migraines with focal neurologic deficits following cranial irradiation for central nervous system *** recovery,which ranges from hours to days to weeks,can be partial or *** propose the following diagnostic criteria for SMART：（1） Remote history of therapeutic external beam cranial irradiation for malignancy;（2） prolonged,reversible clinical manifestations mostly years after irradiation,which may include migraine,seizures,hemiparesis,hemisensory deficits,visuospatial defect,aphasia,confusion and so on;（3） reversible,transient,unilateral cortical gadolinium enhancement correlative abnormal T2 and fluid-attenuated inversion recovery signal of the affected cerebral region;（4） eventual complete or partial recovery,the length of duration of recovery ranging from hours to days to weeks;（5） no evidence of residual or recurrent tumor;（6） not attributable to another *** date,no specific treatment has been identified for this ***：SMART is an extremely rare delayed complication of brain ***,improvements in cancer survival rates have resulted in a rise in its ***,awareness and recognition of the syndrome is important to make a rapid diagnosis and avoid aggressive interventions such as brain biopsy and cerebral angiography.

关键词： Cranial Irradiation Epilepsy Migraine Stroke-like Migraine Attacks after Radiation Therapy

Chinese Massage Therapy for Ankle Injury

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Journal of Acupuncture and Tuina Science 2003年第5期1卷 56-57页

作者： CHEN ming-xia li Nian-qun HUANG Guo-qi Department of Chinese Medicine Navy No.411 Hospital Shanghai China 200081 Department of Chinese Medicine Navy No.411 Hospital Shanghai China 200081

Purpose: To explore the therapeutic methods and effects in the treatment of acute and chronic injuries of the ankle joint by Chinese massage therapy in combination with external application of Chinese herbal drugs and functional ***: Totally, 36 cases of the patients with acute soft tissue injury, chronic soft tissue injury and post-fracture sequelae of the ankle joint were treated by Chinese massage therapy, external application or external wash of Chinese herbal drugs, and exercises of dorsal flexion and extension of the ankle joint, to observe the restoration of the ankle ***: In 36 cases of the patients, the results showed remarkable effect in 18 cases, effect in 16 cases, failure in 2 cases and the effective rate in 94.4%.Conclusion: The combined use of Chinese massage therapy, external application of Chinese herbal drugs and functional exercises can produce precise effect in the treatment of soft tissue injury of the ankle joint. Key Words Ankle Injuries - Tuina - Massage Author: CHEN ming-xia (1971-), female, physicianTranslator: HUANG Guo-qi

关键词： Ankle Injuries Tuina Massage