检索结果-南通市图书馆

Comparison between visual clinical examination and the replica method for assessments of sealant retention over a 2-year period

在线全文

学校读者我要写书评

暂无评论

International Journal of Oral Science 2014年第2期6卷 111-115页

作者： Xuan Hu Xi Chen Lu Ye ming-wen fan Marie-Charlotte Huysmans Jo E Frencken State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education School and Hospital of Stomatology Wuhan University Department of Preventive Dentistry School and Hospital of Stomatology Wuhan University Private Practitioner Department of Preventive and Restorative Dentistry College of Dental Sciences Radboud University Nijmegen Medical Centre Nijmegen The Netherlands Department of Global Oral Health College of Dental Sciences Radboud University Nijmegen Medical Centre Nijmegen The Netherlands

To compare the levels of agreement and the survival rates of sealant retention for different sealing materials over a 2-year period assessed using the visual clinical examination and replica methods, sealant retention data were obtained by visual clinical examination and from replicas of the same sealed tooth at baseline and at 0.5-, 1- and 2-year evaluation points in 407 children and were compared for agreement using kappa coefficients. Survival curves of retained sealants on occlusal surfaces were created using modified categorisation （fully retained sealants and those having all pits and fissures partly covered with the sealant material versus completely lost sealants that included pit and fissure systems that had /〉 1 pit re-exposed） according to the Kaplan-Meier method. The kappa coefficient for the agreement between both assessment methods over the three evaluation time points combined was 0.38 （95% confidence interval （CI）： 0.35-0.41）. More sealant retention was observed from replicas than through visual clinical examination. Cumulative survival curves at the three evaluation times were not statistically significantly higher when assessed from replicas （P=0.47）. Using the replica method, more retained sealant material was observed than through visual clinical examination during the 2-year period. This finding did not result in a difference in the survival rates of sealants assessed by the two assessment methods. When replicas cast in die stone are used for assessing sealant retention, the level of reliability of the data is higher than that of data obtained through the commonly used visual clinical examination, particularly if such assessments are conducted over time.

关键词： clinical examination replica method sealant retention sealant

Identification and Isolation of Human Dental Pulp Stem Cells

在线全文

学校读者我要写书评

暂无评论

生物医学工程学杂志 2005年第S1期22卷 101-102页

作者： Xue-Chao YANG ming-wen fan(Ministry Education Key Lab. For Oral Biomedical Engineering, Shool of Stomatology, Wuhan University,Wuhan 430079,China) Ministry Education Key Lab. For Oral Biomedical Engineering Shool of Stomatology Wuhan University Wuhan 430079 China

1 IntroductionDentinal repair in the postnatal organism occurs through the activity of specialized cells, odontoblasts,that are thought to be maintained by an as yet undefined precursor population associated with pulp... 详细信息

关键词： cell DPSCs Identification and Isolation of Human Dental Pulp Stem Cells DSPP

Immunolocalization of secretion complex in Streptococcus mutans

在线全文

学校读者我要写书评

暂无评论

Journal of Microbiology and Immunology 2007年第1期5卷 13-16页

作者： PING HU ZHUAN BIAN ming wen fan MIN NIE Key Laboratory for Oral Biomedical Engineering of Ministry of Education School and Hospital of Stomatology Wuhan University P. R. China

Each secretion （See） machinery minimally consists of three integral inner membrane pro- teins SecYEG. In order to know the distribution pattern of the Sec complex in Streptococcus mutans, we explored the subcellular localization of SecY. The anti-secY antibody was examined on Western blots to evaluate specificity. An indirect post-embedding immunogold method was used to determine the subcellular localization of the SecY in the cytoplasmic membrane of the Streptococcus mutans GS-5. lmmunoblotting experiments showed that the anti-seeY antibody specifically recognized a single band of about 47.8 kDa. Immunogold electron microscopy image of section with anti-secY antibody revealed a single intense focus of gold particles at a discrete location on the cytoplasmic membrane of the Streptococcus mutans GS-5. SecY clustered to an asymmetric microdomain, which indicated for the first time that See complex presented a unisite on the cytoplasmic membrane of Streptococcus mutans.

关键词： Streptococcus mutans Secretion complex SecY

Experimental Study on Geometry Characteristics of Turbulent Premixed Flames for Natural Gas/Air Mixtures

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2025年第1期34卷 268-282页

作者： ZHENG Weilin WANG Qijiao XIAO Huahua CHEN Xiaoxiao XIE fan ZENG wen Liaoning Key Lab of Advanced Test Technology for Aerospace Propulsion System Shenyang Aerospace University State Key Laboratory of Fire Science University of science and Technology of China AVIC Shenyang Aircraft Design and Research Institute

In this study,focusing on the geometry characteristics of spherical expanding flame,the turbulent premixed flames of natural gas/air mixtures were investigated in a fan-stirred turbulent *** effects of initial temperature（T=300-400 K）,initial pressure（P=0.1-0.3 MPa）,turbulence intensity（u'=1.0-2.7 m/s）,oxygen volumetric percentage(φ（O2）=15%-21%) and carbon dioxide volumetric percentage(φ（CO2）=0-20%)were delved *** flame profile under the Cartesian coordinate system was derived from the schlieren images taken by the high-speed ***,from both macroscopic and microscopic perspectives,the influence of experimental conditions on the flame geometry characteristics was explored through flame front extraction,wavelet decomposition and network *** results demonstrate that for significant flame wrinkling,changes in species concentrations and turbulence intensity have more pronounced effects on the flame wrinkling *** wrinkling of the flame front maintains a certain degree of similarity,as evidenced by the locally concentrated distribution of the angles of the maximum fluctuation *** disturbance energy under large-scale（D6-D8） disturbances exhibits relatively high values with a similar trend,exerting a significant impact on the geometry characteristics of the flame *** peaks of correlation degree are scattered either with the decomposition scale or the development of flame radius,indicating no linear correlation between different detail ***,the probability distribution of node degrees in key wrinkled regions exhibits different trends with that of large-scale wrinkling and disturbance energy,especially with changes in initial *** occurs because the number of key wrinkles varies based on the perturbation's strength or the region's ***,an increase in the fluctuation frequency of the flame's local radius may not necessarily lead to an increase in the number of key folded regions.

关键词： fan-stirred turbulent combustor geometry characteristics large-scale wrinkling network topology wavelet decomposition

Enhanced efficacy of CTLA-4 fusion anti-caries DNA vaccines in gnotobiotic hamsters

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Acta Pharmacologica Sinica 2007年第8期28卷 1236-1242页

作者： Feng ZHANG~3 Yu-hong LI~3 ming-wen fan~2 Rong JIA Qing-an XU Ji-hua GUO Fei YU Qi-wei TIAN Key Laboratory for Oral Biomedical Engineering of Ministry of Education,School and Hospital of Stomatology,Wuhan University,Wuhan 430079,China Key Laboratory for Oral Biomedical Engineering of Ministry of Education School and Hospital of Stomatology Wuhan University Wuhan China

Aim:To evaluate the comparative immunogenicity and protective efficacy of thecytotoxic T-lymphocyte-associated antigen 4(CTLA-4)fusion anti-caries DNAvaccines pGJA-P/VAX1,pGJA-P,and non-fusion anti-caries DNA constructpGLUA-P in *** addition,the ability of CTLA-4 to target pGJA-P/VAX 1-encoding antigen to dendritic cells was tested in ***:All DNAconstructs contain genes encoding the A-P regions of a cell surface protein(PAc)and the glucan binding(GLU)domain of glucosyltransferases(GTFs)of cari-ogenic organism Streptococcus *** dendritic cells were mixed withthe CTLA-4-Ig-GLU-A-P protein expressed by pGJA-P/VAX1-transfected cellsand analyzed by flow *** hamsters were immunized with anti-caries DNA vaccines by intramuscular injection or intranasal *** responses to a representative antigen PAc were assayed by ELISA,andcaries protection was evaluated by Keyes caries ***:A flow cytometricanalysis demonstrated that CTLA-4-Ig-GLU-A-P protein was capable of bind-ing to human dendritic cells,pGJA-P/VAX1 and pGJA-P induced significantlyhigher specific salivary and serum anti-PAc antibody responses than pGLUA-ESignificantly fewer caries lesions were also observed in hamsters immunized withpGJA-P/VAX1 and *** was no significant difference in the anti-PAcantibody level or caries scores between pGJA-P/VAX1 and ***:Antigen encoded by CTLA-4 fusion anti-caries DNA vac-cine pGJA-P/VAX1 could specifically bind to human dendritic cells through theinteraction of CTLA-4 and B7 *** antigen to CTLA-4 has beenproven to greatly enhance the immunogenicity and protective efficacy of anti-caries DNA vaccines.

关键词： DNA vaccines Streptococcus mutans dendritic cells cytotoxic T-lymphocyteassociated antigen 4

Dynamic Regulation of Hydrogen Bonding Networks and Solvation Structures for Synergistic Solar‑Thermal Desalination of Seawater and Catalytic Degradation of Organic Pollutants

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第2期17卷 548-565页

作者： ming‑Yuan Yu Jing Wu Guang Yin fan‑Zhen Jiao Zhong‑Zhen Yu Jin Qu Beijing Key Laboratory of Advanced Functional Polymer Composites Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China State Key Laboratory of Organic‑Inorganic Composites College of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029People’s Republic of China

Although solar steam generation strategy is efficient in desalinating seawater,it is still challenging to achieve continuous solar-thermal desalination of seawater and catalytic degradation of organic ***,dynamic regulations of hydrogen bonding networks and solvation structures are realized by designing an asymmetric bilayer membrane consisting of a bacterial cellulose/carbon nanotube/Co_(2)(OH)_(2)CO_(3)nanorod top layer and a bacterial cellulose/Co_(2)(OH)_(2)CO_(3)nanorod(BCH)bottom ***,the hydrogen bonding networks inside the membrane can be tuned by the rich surface–OH groups of the bacterial cellulose and Co_(2)(OH)_(2)CO_(3)as well as the ions and radicals in situ generated during the catalysis ***,both SO_(4)^(2−)and HSO_(5)−can regulate the solvation structure of Na^(+)and be adsorbed more preferentially on the evaporation surface than Cl^(−),thus hindering the de-solvation of the solvated Na^(+)and subsequent nucleation/growth of ***,the heat generated by the solar-thermal energy conversion can accelerate the reaction kinetics and enhance the catalytic degradation *** work provides a flow-bed water purification system with an asymmetric solar-thermal and catalytic membrane for synergistic solar thermal desalination of seawater/brine and catalytic degradation of organic pollutants.

关键词： Solar steam generation Seawater desalination Catalytic degradation Bacterial cellulose Cobalt hydroxycarbonate nanorods

Effects of aggregate size distribution and carbon nanotubes on the mechanical properties of cemented gangue backfill samples under true triaxial compression

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 311-324页

作者： Qian Yin fan wen Zhigang Tao Hai Pu Tianci Deng Yaoyao Meng Qingbin Meng Hongwen Jing Bo Meng Jiangyu Wu State Key Laboratory of Intelligent Construction and Healthy Operation and Maintenance of Deep Underground Engineering China University of Mining and TechnologyXuzhou 221116China State Key Laboratory of Mining Response and Disaster Prevention and Control in Deep Coal Mines Anhui University of Science and TechnologyHuainan 232001China State Key Laboratory for Geomechanics&Deep Underground Engineering China University of Mining and Technology(Beijing)Beijing 100083China Key Laboratory of Xinjiang Coal Resources Green Mining Ministry of EducationXinjiang Institute of EngineeringUrumqi 830023China

The mechanical behavior of cemented gangue backfill materials(CGBMs)is closely related to particle size distribution(PSD)of aggregates and properties of cementitious ***,the true triaxial compression tests,CT scanning,SEM,and EDS tests were conducted on cemented gangue backfill samples(CGBSs)with various carbon nanotube concentrations(P_(CNT))that satisfied fractal theory for the PSD of *** mechanical properties,energy dissipations,and failure mechanisms of the CGBSs under true triaxial compression were systematically *** results indicate that appropriate carbon nanotubes(CNTs)effectively enhance the mechanical properties and energy dissipations of CGBSs through micropore filling and microcrack bridging,and the optimal effect appears at P_(CNT)of 0.08wt%.Taking PSD fractal dimension(D)of 2.500 as an example,compared to that of CGBS without CNT,the peak strength(σ_(p)),axial peak strain(ε_(1,p)),elastic strain energy(Ue),and dissipated energy(U_(d))increased by 12.76%,29.60%,19.05%,and90.39%,***,excessive CNTs can reduce the mechanical properties of CGBSs due to CNT agglomeration,manifesting a decrease inρ_(p),ε_(1,p),and the volumetric strain increment(Δε_(v))when P_(CNT)increases from 0.08wt%to 0.12wt%.Moreover,the addition of CNTs improved the integrity of CGBS after macroscopic failure,and crack extension in CGBSs appeared in two modes:detour and pass through the ***σ_(p)and U_(d)firstly increase and then decrease with increasing D,and porosity shows the opposite ***ε_(1,p)andΔε_(v)are negatively correlated with D,and CGBS with D=2.150 has the maximum deformation parameters(ε_(1,p)=0.05079,Δε_(v)=0.01990)due to the frictional slip effect caused by coarse *** increasing D,the failure modes of CGBSs are sequentially manifested as oblique shear failure,"Y-shaped"shear failure,and conjugate shear failure.

关键词： cemented gangue backfill materials particle size distribution true triaxial compression test carbon nanotubes mechanical properties failure modes

Visualization of the protective role of estrogen against female liver fibrosis via an ER viscosity NIR fluorescent probe

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2025年第1期68卷 360-368页

作者： Zheng Liu Changyu Zhang Zipeng Li Wanying Ma Jia Liu Xiang Xia Ning Xu wen Sun Jianjun Du Jiangli fan Xiaojun Peng State Key Laboratory of Fine Chemicals Dalian University of Technology Ningbo Institute of Dalian University of Technology

Endoplasmic reticulum(ER) viscosity has emerged as a new potential biomarker for hepatic fibrosis(HF). Herein, we report the first ER-targeting viscosity-responsive near-infrared(NIR) fluorescent probe HBT-PP for investigations of HF *** twisted intramolecular charge transfer(TICT) and the excited state intramolecular proton transfer(ESIPT) are combined to endow HBT-PP with the selective response towards viscosity(～62-fold) and a super large stokes shift(～320 nm). HBT-PP mainly targets organelle ER and is able to image the drug-or alcohol-induced viscosity elevation in living cells. Significantly,HBT-PP was successfully applied to visualize the gender difference in HF and the protective role of estrogen in restraining HF progression. Of note, after 10 min of stain with HBT-PP, HF lesions showed a stage-based response, indicating the potential of this probe in fast and early diagnosis of HF. These results clearly demonstrated the promising application of HBT-PP as a new tool for exploring ER viscosity-involved physiological and pathological processes.

关键词： NIR fluorescent probe ER viscosity hepatic fibrosis gender difference estrogen

基于协方差模糊评价的内河集装箱码头铁水联运效率方法研究

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

铁道运输与经济 2017年第7期39卷 83-88页

作者：刘名武樊文平重庆交通大学经济与管理学院重庆400074

为评价内河集装箱码头铁水联运运营效率,针对评价过程中定量指标与定性指标共存的问题,提出基于协方差模糊评价的效率评价方法,通过协方差判断矩阵和模糊评价法分别确定定量指标与定性指标权重系数,构建协方差模糊评价模型。选取寸滩、... 详细信息

为评价内河集装箱码头铁水联运运营效率,针对评价过程中定量指标与定性指标共存的问题,提出基于协方差模糊评价的效率评价方法,通过协方差判断矩阵和模糊评价法分别确定定量指标与定性指标权重系数,构建协方差模糊评价模型。选取寸滩、武汉和肇庆?3?个典型铁水联运枢纽内河集装箱码头作为研究对象,构建铁水联运效率评价指标体系,通过实例分析发现评价结果与各码头实际铁水联运效率值相符合,证明协方差模糊评价法具有一定的合理性与有效性,同时评价结果可以为铁水联运管理者提供决策参考。

关键词：铁水联运内河集装箱码头运营效率协方差模糊评价