检索结果-南通市图书馆

Multilevel analysis of the central-peripheral-target organ pathway:contributing to recovery after peripheral nerve injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2807-2822页

作者： Xizi Song Ruixin li Xiaolei Chu Qi li Ruihua li Qingwen li Kai-Yu Tong Xiaosong Gu Dong ming Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Haihe Laboratory of Brain-Machine Interface and Human-Machine Fusion TianjinChina Department of Rehabilitation Tianjin University Tianjin HospitalTianjinChina Department of Hand Microsurgery Tianjin University Tianjin HospitalTianjinChina School of Exercise and Health Tianjin University of SportTianjinChina Department of Biomedical Engineering the Chinese University of Hong KongHong Kong Special Administrative RegionChina

Peripheral nerve injury is a common neurological condition that often leads to severe functional limitations and *** on the pathogenesis of peripheral nerve injury has focused on pathological changes at individual injury sites,neglecting multilevel pathological analysis of the overall nervous system and target *** has led to restrictions on current therapeutic *** this paper,we first summarize the potential mechanisms of peripheral nerve injury from a holistic perspective,covering the central nervous system,peripheral nervous system,and target *** peripheral nerve injury,the cortical plasticity of the brain is altered due to damage to and regeneration of peripheral nerves;changes such as neuronal apoptosis and axonal demyelination occur in the spinal *** nerve will undergo axonal regeneration,activation of Schwann cells,inflammatory response,and vascular system regeneration at the injury *** damage to target organs can occur,including skeletal muscle atrophy and sensory receptor *** then provide a brief review of the research advances in therapeutic approaches to peripheral nerve *** main current treatments are conducted passively and include physical factor rehabilitation,pharmacological treatments,cell-based therapies,and physical ***,most treatments only partially address the problem and cannot complete the systematic recovery of the entire central nervous system-peripheral nervous system-target organ ***,we should further explore multilevel treatment options that produce effective,long-lasting results,perhaps requiring a combination of passive(traditional)and active(novel)treatment methods to stimulate rehabilitation at the central-peripheral-target organ levels to achieve better functional recovery.

关键词： central nervous system central peripheral target organ multilevel pathological analysis nerve regeneration peripheral nerve injury peripheral nervous system target organs therapeutic approach

云南3种棕榈藤材材性分析及开发利用价值评价

在线全文

学校读者我要写书评

暂无评论

西北林学院学报 2016年第4期31卷 265-268页

作者：曹积微袁哲强明礼西南林业大学材料工程学院云南昆明650224

对云南省藤、版纳省藤、钩叶藤的物理力学性能、化学组成和藤材纤维形态进行测定和分析。结果表明,云南省藤基本密度和气干密度最大,干缩率小,顺纹抗压强度较大,抗弯强度和抗弯弹性模量远大于其他2种藤材;版纳省藤干缩率较大;钩叶藤抗... 详细信息

对云南省藤、版纳省藤、钩叶藤的物理力学性能、化学组成和藤材纤维形态进行测定和分析。结果表明,云南省藤基本密度和气干密度最大,干缩率小,顺纹抗压强度较大,抗弯强度和抗弯弹性模量远大于其他2种藤材;版纳省藤干缩率较大;钩叶藤抗弯强度和抗弯弹性模量均为最差且藤芯脆弱,但抗压强度与版纳省藤相当。钩叶藤综纤维素含量最高,版纳省藤最低;云南省藤木质素和聚戊糖含量最高,苯醇抽提物、冷水抽提物和1%NaOH抽提物含量均为最低。纤维长、宽度均以钩叶藤较大,且外部近藤皮纤维长度明显大于藤芯部纤维;径向纤维长宽比和纤维壁腔比变异以版纳省藤和云南省藤较小,以钩叶藤较大。在加工利用中,云南省藤材性最好,材质均匀,版纳省藤次之;钩叶藤属于劣质藤,藤茎内外材性差异较大,但纤维具有较高开发利用价值。

关键词：棕榈藤物理力学性质化学成分纤维形态

在线全文

学校读者我要写书评

暂无评论

云南藏区木结构建筑的现状与展望

木材工业 2013年第4期27卷 25-28页

作者：强明礼任海青杜官本西南林业大学材料工程学院云南昆明650224 中国林科院木材工业研究所北京100091

云南藏区木结构建筑地域特色鲜明,但由于缺乏针对性的研究和现代科技支撑,面临着民族技艺传承及可持续发展的障碍。在实地调研基础上,总结云南藏区木结构建筑的类型、构造、用材特点及存在问题,并提出发展建议。

关键词：云南藏区木结构建筑

Effects of the extrusion parameters on microstructure,texture and room temperature mechanical properties of extruded Mg-2.49Nd-1.82Gd-0.2Zn-0.2Zr alloy

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 136-146页

作者： Chenjin Zhang Guangyu Yang Lei Xiao Zhiyong Kan Jing Guo qiang li Wanqi Jie State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’an 710072China College of Materials Science and Engineering Fuzhou UniversityFuzhou 350108China College of Chemistry and Environmental Science Qujing Normal UniversityQujing 655011China

Microstructure,texture,and mechanical properties of the extruded Mg-2.49Nd-1.82Gd-0.2Zn-0.2Zr alloy were investigated at different extrusion temperatures(260 and 320℃),extrusion ratios(10:1,15:1,and 30:1),and extrusion speeds(3 and 6 mm/s).The experimental results exhibited that the grain sizes after extrusion were much finer than that of the homogenized alloy,and the second phase showed streamline distribution along the extrusion direction(ED).With extrusion temperature increased from 260 to 320℃,the microstructure,texture,and mechanical properties of alloys changed *** dynamic recrystallization(DRX)degree and grain sizes enhanced as the extrusion ratio increased from 10:1 to 30:1,and the strength gradually decreased but elongation(EL)*** the extrusion speed increased from 3 to 6 mm/s,the grain sizes and DRX degree increased significantly,and the samples presented the typical-rare-earth(RE)*** alloy extruded at 260℃ with extrusion ratio of 10:1 and extrusion speed of 3 mm/s showed the tensile yield strength(TYS)of 213 MPa and EL of 30.6%.After quantitatively analyzing the contribution of strengthening mechanisms,it was found that the grain boundary strengthening and dislocation strengthening played major roles among strengthening *** results provide some guidelines for enlarging the industrial application of extruded Mg-RE alloy.

关键词： Mg-rare earth alloys extrusion temperature extrusion ratio extrusion speed strengthening mechanisms

在线全文

学校读者我要写书评

暂无评论

现代藤家具加工工艺技术研究

西南林学院学报 2008年第2期28卷 77-80页

作者：强明礼袁哲西南林学院木质科学与装饰工程学院云南昆明650224

现代藤家具浪漫优雅,倍受人们的青睐.从骨架制作工艺、编织工艺及涂饰工艺3方面对现代藤家具的加工工艺技术进行研究,以期对藤家具的结构设计、加工制造有所帮助.

关键词：藤家具加工工艺家具结构

在线全文

学校读者我要写书评

暂无评论

林业类高等院校家具设计课程教学方法的探讨

高教论坛 2015年第8期 64-66页

作者：袁哲强明礼西南林业大学艺术学院云南昆明650224 西南林业大学材料工程学院云南昆明650224

根据当前的教学现状,提出了林业类高等院校家具设计课程的教学应综合利用教师课堂讲授法、案例教学法、主题教学法及项目教学法,才能达到良好的教学效果。从家具设计的课程体系入手,分析了不同的教学内容适宜的教学方法,同时通过一些教... 详细信息

根据当前的教学现状,提出了林业类高等院校家具设计课程的教学应综合利用教师课堂讲授法、案例教学法、主题教学法及项目教学法,才能达到良好的教学效果。从家具设计的课程体系入手,分析了不同的教学内容适宜的教学方法,同时通过一些教学案例来分析这些方法的应用。

关键词：家具设计教学方法创新实践

Magnetron sputtered nickel oxide with suppressed interfacial defect states for efficient inverted perovskite solar cells

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 348-355页

作者： Guoqiang Ma Qin Tan Zhaoning li Jingwei Xiu Jiafeng Wang Tianle Cheng Dong He qiang Sun Xuhang Ma Francesco Lamberti Zhubing He Department of Materials Science and Engineering Institute of Innovative Materials (I2M) Shenzhen Key Laboratory of Full Spectral Solar Electricity Generation (FSSEG)Southern University of Science and Technology (SUSTech) Core Research Facilities Southern University of Science and Technology Department of Chemical Sciences Department of Industrial Engineering University of Padova

Widely used spin-coated nickle oxide （NiOx） based perovskite solar cells often suffer from severe interfacial reactions between the NiOxand adjacent perovskite layers due to surface defect states,which inherently impair device performance in a long-term view,even with surface molecule *** this study,we developed high-quality magnetron-sputtered NiOxthin films through detailed process optimization,and compared systematically sputtered and spin-coated NiOxthin film surfaces from materials to *** sputtered NiOxfilms exhibit improved crystallinity,smoother surfaces,and significantly reduced Ni3+or Ni vacancies compared to their spin-coated ***,the interface between the perovskite and sputtered NiOxfilm shows a substantially reduced density of defect *** solar cells （PSCs） fabricated with our optimally sputtered NiOxfilms achieved a high power conversion efficiency （PCE） of up to 19.93%and demonstrated enhanced stability,maintaining 86.2% efficiency during 500 h of maximum power point tracking under one standard sun ***,with the surface modification using (4-(2,7-dibromo-9,9-dimethylacridin-10（9H）-yl)butyl)p hosphonic acid （DMAcPA）,the device PCE was further promoted to 23.07%,which is the highest value reported for sputtered NiOxbased PSCs so far.

关键词： Nickle oxide Magnetron sputter Defect Stability Perovskite solar cell

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

实木椅零部件的相似性与成组技术

林产工业 2019年第7期46卷 48-52页

作者：徐俊华强明礼任海青李军西南林业大学艺术与设计学院昆明650224 中国林业科学研究院木材工业研究所北京100091 南京林业大学家居与工业设计学院南京210037

以实木椅为研究对象,根据零部件的相似性,将其分类成组,形成零件族。测量和统计零件族中各零部件的规格尺寸,并根据时间研究法测定和统计各零部件的加工时间。按照成组技术来组织生产,分析成组加工前后的时间差异,进而估算成组加工前后... 详细信息

以实木椅为研究对象,根据零部件的相似性,将其分类成组,形成零件族。测量和统计零件族中各零部件的规格尺寸,并根据时间研究法测定和统计各零部件的加工时间。按照成组技术来组织生产,分析成组加工前后的时间差异,进而估算成组加工前后的成本差异。结果表明:实木椅零部件之间在加工工艺、几何形状、尺寸规格等方面存在一定的相似性,符合成组技术实施的条件;利用相似性特征将零部件分类形成零件族后实施成组加工,可以有效提升生产效率,显著降低生产成本。

关键词：实木椅零部件相似性成组技术时间研究

Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology,cognition,and behavior in APP/PS1 mice

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第2期20卷 533-547页

作者： Yanli Zhang Tian li Jie Miao Zhina Zhang mingxuan Yang Zhuoran Wang Bo Yang Jiawei Zhang Haiting li qiang Su Junhong Guo Department of Neurology First Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Neurology Sixth Hospital of Shanxi Medical University(General Hospital of Tisco)TaiyuanShanxi ProvinceChina Department of Physiology Key Laboratory of Cellular PhysiologyMinistry of EducationShanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Hernia and Abdominal Wall Surgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Laboratory Medicine of Fenyang College Shanxi Medical UniversityFenyangShanxi ProvinceChina

In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial ***,the functional role of GGT5 in the development of Alzheimer’s disease remains *** study aimed to explore the effect of GGT5 on cognitive function and brain pathology in an APP/PS1 mouse model of Alzheimer’s disease,as well as the underlying *** observed a significant reduction in GGT5 expression in two in vitro models of Alzheimer’s disease(Aβ_(1-42)-treated hCMEC/D3 and bEnd.3 cells),as well as in the APP/PS1 mouse ***,injection of APP/PS1 mice with an adeno-associated virus encoding GGT5 enhanced hippocampal synaptic plasticity and mitigated cognitive ***,increasing GGT5 expression in cerebrovascular endothelial cells reduced levels of both soluble and insoluble amyloid-βin the brains of APP/PS1 *** effect may be attributable to inhibition of the expression ofβ-site APP cleaving enzyme 1,which is mediated by nuclear factor-kappa *** findings demonstrate that GGT5 expression in cerebrovascular endothelial cells is inversely associated with Alzheimer’s disease pathogenesis,and that GGT5 upregulation mitigates cognitive deficits in APP/PS1 *** findings suggest that GGT5 expression in cerebrovascular endothelial cells is a potential therapeutic target and biomarker for Alzheimer’s disease.

关键词： Alzheimer’s disease amyloid-β APP/PS1 mice cerebrovascular endothelial cells cognitive deficits gamma-glutamyl transferase 5 neurovascular unit nuclear factor‐kappa B synaptic plasticity β-site APP cleaving enzyme 1