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Osteogenic enhancement of low intensity pulsed ultrasound on bone marrow mesenchymal stem cell

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Osteogenic enhancement of low intensity pulsed ultrasound on...

High-Resolution Infrared-Vacuum Ultraviolet Photoion and Pulsed Field Ionization-Photoelectron Methods for Spectroscopic Studies of Neutrals and Cations

International Conference on Osteoporosis and Bone Research 2008

作者： Fan Fong Celine Hui kwong Man Lee Kwok Sui Leung Chun yiu Jack Cheng Department of Orthopaedics and Traumatology The Chinese University of Hong KongHong KongChina Lee Hysan Clinical Research Laboratories The Chinese University of Hong KongHong KongChina

＜正＞Objective:Low intensity pulsed ultrasound （LIPUS） is known to accelerate mineralization and bone regeneration,but the osteogenic effect on mesenchymal stem cells （MSCs） is still *** study investigated the ef...

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来源： cnki会议评论

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Chinese Journal of Chemical Physics 2008年第3期21卷 193-201页

作者： Xi Xing Beth Reed Mi Kyung Bahng Peng Wang Hin Koo Woo Sun Jong Baek Chee Shing Lain Cheuk yiu Ng Department of Chemistry University of California Davis Davis California 95616 USA

We show that by scanning the frequency of a single mode infrared （IR） optical parametric oscillator （IR- OPO） laser to excite the molecular species of interest and fixing the frequency of a vacuum ultraviolet （VUV） laser to photoionize the IR excited species, high-resolution IR spectra of polyatomic neutrals can be obtained with high sensitivity. The fact that this IR-VUV-photoion （IR-VUV-PI） method is based on VUV photoionization probe, and thus, allows the identification of the neutral IR absorber, makes it applicable for IR spectroscopy measurements of isotopemers, radicals, and clusters, which usually exist as impure samples. The highly resolved IR-VUV-PI measurements achieved using the single mode IR-OPO laser have made possible the selection of single rovibrational states of CH3X （X=Br and I）, C2H4, and C3H4 for VUV-pulsed field ionization-photoelectron （VUV-PFI-PE） measurements, resulting in rovibrationally resolved photoelectron spectra for these polyatomic molecules. These experiments show that the signal- to-noise ratios of the IR-VUV-PI and IR-VUV-PFI-PE spectra obtained by employing the high-resolution IR-OPO laser are significantly higher than those observed in previous IR-VUV-PI and IR-VUV-PFI-PE studies using a low-resolution IR-OPO laser. Further improvement in sensitivity of IR-VUV-PI and IR- VUV-PFI-PE measurements by using the collinear arrangement of IR-VUV lasers and molecular beam is discussed.

关键词： Vacuum ultraviolet Infrared Pulse-field photoelectron High resolution

Server-Aided Multi-Secret Sharing Scheme for Weak Computational Devices

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Computers, Materials & Continua 2018年第9期56卷 401-414页

作者： En Zhang Xintao Duan Siuming yiu Junbin Fang Zoe L.Jiang Tsz HonYuen Jie Peng College of Computer and Information Engineering Henan Normal UniversityXinxiang453007China Lab of Intelligence Business&Internet of Things of Henan Province Xinxiang453007China Department of Computer Science University of Hong KongHong KongChina Department of Optoelectronic Engineering Jinan UniversityGuangzhou510632China School of Computer Science and Technology Harbin nstitute of Technology Shenzhen Graduate SchoolShenzhen518055China Huawei Singapore

In the setting of(t,n)threshold secret sharing,at least t parties can reconstruct the secret,and fewer than t parties learn nothing about the ***,to achieve fairness,the existing secret sharing schemes either assume a trusted party exists or require running multi-round,which is not practical in a real *** addition,the cost of verification grows dramatically with the number of participants and the communication complexity is O(t),if there is not a trusted combiner in the reconstruction *** this work,we propose a fair server-aided multi-secret sharing scheme for weak computational *** malicious behavior of clients or server providers in the scheme can be verified,and the server provider learns nothing about the secret shadows and the *** other secret sharing schemes,our scheme does not require interaction among users and can work in asynchronous mode,which is suitable for mobile networks or cloud computing environments since weak computational mobile devices are not always ***,in the scheme,the secret shadow is reusable,and expensive computation such as reconstruction computation and homomorphic verification computation can be outsourced to the server provider,and the users only require a small amount of computation.

关键词： Secret sharing server-aided non-interactive fairness

A promising diagnostic method:Terahertz pulsed imaging and spectroscopy

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World Journal of Radiology 2011年第3期3卷 55-65页

作者： ming yiu Sy Yi-Xiang J Wang Anil T Ahuja Emma Pickwell-MacPherson Department of Electronic Engineering The Chinese University of Hong Kong Department of Imaging and Interventional Radiology The Chinese University of Hong Kong Department of Electronic and Computer Engineering Hong Kong University of Science and Technology

The terahertz band lies between the microwave and infrared regions of the electromagnetic *** radiation has very low photon energy and thus it does not pose any ionization hazard for biological *** is strongly attenuated by water and very sensitive to water *** absorption spectra due to intermolecular vibrations in this region have been found in different biological *** unique features make tera-hertz imaging very attractive for medical applications in order to provide complimentary information to existing imaging *** has been an increasing interest in terahertz imaging and spectroscopy of biologically related applications within the last few years and more and more terahertz spectra are being *** paper introduces terahertz technology and provides a short review of recent advances in terahertz imaging and spectroscopy techniques,and a number of applications such as molecular spectroscopy,tissue characterization and skin imaging are discussed.

关键词： Biomedical Imaging Spectroscopy Terahertz

Virtual reality based multiple life skill training for intellectual disability:A multicenter randomized controlled trial

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Engineered Regeneration 2022年第2期3卷 121-130页

作者： James Chung-Wai Cheung ming Ni Andy yiu-Chau Tam Tim Tin-Chun Chan Alyssa Ka-Yan Cheung Ocean Yu-Hong Tsang Chi-Bun Yip Wing-Kai Lam Duo Wai-Chi Wong Department of Biomedical Engineering Faculty of EngineeringThe Hong Kong Polytechnic UniversityHong Kong 999077China Research Institute for Smart Ageing The Hong Kong Polytechnic UniversityHong Kong 999077China Jockey Club Smart Ageing Hub Department of Biomedical EngineeringFaculty of EngineeringThe Hong Kong Polytechnic UniversityHong Kong 999077China Department of Orthopaedics Pudong New Area People’s Hospital Affiliated to Shanghai Jiaotong UniversityShanghai 201299China Social Service Department Yan Chai HospitalHong Kong 999077China C2 Innovations and Research Limited Hong Kong 999077China Department of Kinesiology Shenyang Sport UniversityShenyang 110102China Sports Information and External Affairs Centre Hong Kong Sports InstituteHong Kong 999077China

Life skill-based training is essential for intellectual disabled individuals to regain autonomy and social *** reality(VR)could deliver a nascent application that is more engaging and *** objective of this study was to evaluate the training effects of the VR-based multiple life skill training program on life skill perfor-mance,self-efficacy,memory,cognitive and behavioral functions via a multicenter randomized controlled trial.A total of 145 intellectual disabled participants were recruited for a randomized controlled trial with three in-tervention arms:VR(n=42);traditional(n=53);and control(n=50).The life skill tasks for the interventions included 1)grocery shopping,2)cooking,and 3)kitchen *** measures were performance scores for the three tasks,self-efficacy scale,digit span score,and Frontal Assessment Battery score,graded by blinded ***-after effects of each group were evaluated using separated Wilcoxon Signed-rank *** sig-nificantly improved cooking,cleaning performance,and memory span,while traditional training significantly improved shopping,cooking,and cleaning *** generalized estimating equation evaluated effects between groups adjusted for age,gender and intelligence quotient(IQ).VR had significantly larger improvement effects in cooking and cleaning than the control group and memory span compared to traditional training and controls *** appeared to be a significant confounder on the training *** work may consider developing artificial intelligence to customize programs depending on IQ level.

关键词： Mental retardation Intellectual development X-reality Immersive rehabilitation Metaverse

Quantum State-to-State Vacuum Ultraviolet Photodissociation Dynamics of Small Molecules

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Chinese Journal of Chemical Physics 2019年第1期32卷 23-34,I0001页

作者： Hong Gao Cheuk-yiu Ng Beijing National Laboratory for Molecular Sciences (BNLMS) Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China Department of Chemistry University of California Davis CA 95616 USA

The present review focused on selected, recent experimental progress of photodissociation dynamics of small molecules covering the vacuum ultraviolet (VUV) range from 6 eV to 20 eV. These advancements come about due to the available laser based VUV light sources along with the developments of advanced experimental techniques, including the velocitymap imaging (VMI), H-atom Rydberg tagging time-of-flight (HRTOF) techniques, as well as the two-color tunable VUV-VUV laser pump-probe detection method. The applications of these experimental techniques have allowed VUV photodissociation studies of many diatomic and triatomic molecules to quantum state-to-state in detail. To highlight the recent accomplishments, we have summarized the results on several important molecular species, including H2 (D2, HD), CO, N2, NO, O2, H2O (D2O, HOD), CO2, and N2O. The detailed VUV photodissociation studies of these molecules are of astrochemical and atmospheric relevance. Since molecular photodissociation initiated by VUV excitation is complex and is often governed by multiple electronic potential energy surfaces, the unraveling of the complex dissociation dynamics requires state-to-state cross section measurements. The newly constructed Dalian Coherent Light Source (DCLS), which is capable of generating coherent VUV radiation with unprecedented brightness in the range of 50-150 nm, promises to propel the photodissociation experiment to the next level.

关键词： Photodissociation State-to-state Velocity-map imaging

Sequence assembly using next generation sequencing data —challenges and solutions

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Science China(Life Sciences) 2014年第11期57卷 1140-1148页

作者： CHIN Francis Y.L. LEUNG Henry C.M. yiu S.M. Department of Computer Science The University of Hong Kong

Sequence assembling is an important step for bioinformatics *** the help of next generation sequencing(NGS)technology,high throughput DNA fragment(reads)can be randomly sampled from DNA or RNA molecular ***,as the positions of reads being sampled are unknown,assembling process is required for combining overlapped reads to reconstruct the original DNA or RNA *** with traditional Sanger sequencing methods,although the throughput of NGS reads increases,the read length is shorter and the error rate is *** introduces several problems in ***,paired-end reads instead of single-end reads can be sampled which contain more *** existing assemblers cannot fully utilize this information and fails to assemble longer *** this article,we will revisit the major problems of assembling NGS reads on genomic,transcriptomic,metagenomic and metatranscriptomic *** will also describe our IDBA package for solving these *** package has adopted several novel ideas in assembling,including using multiple k,local assembling and progressive depth *** with existence assemblers,IDBA has better performance on many simulated and real sequencing datasets.

关键词： genomic assembling de Bruijn graph paired-end reads next generation sequencing

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鱼乐、真知与浑沌——濠梁之辩的逻辑分析

逻辑学研究 2017年第4期10卷 52-74页

作者：冯耀明香港科技大学人文学部

对于庄子与惠施在濠梁之上的"鱼之乐"的辩论,本文试图论证:庄子并无意图要证明他知道知鱼之乐,他的目的在否证"他者心灵的不可理解/通接性"这一惠子的假定。本文认为庄子的"知"与他的"为一"观念是密切相关的,而庄子的"为一"观念与惠子的... 详细信息

对于庄子与惠施在濠梁之上的"鱼之乐"的辩论,本文试图论证:庄子并无意图要证明他知道知鱼之乐,他的目的在否证"他者心灵的不可理解/通接性"这一惠子的假定。本文认为庄子的"知"与他的"为一"观念是密切相关的,而庄子的"为一"观念与惠子的"一体"观念是截然不同的,二者不可混为一谈。此外,本文还对庄子的实在观进行了讨论。

关键词：安知鱼乐为一一体浑沌真知

Crocodile blood supplementation protect svascular function in diabetic mice

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Food Production, Processing and Nutrition 2021年第1期3卷 283-295页

作者： Chui yiu Bamboo Chook Francis M.Chen Gary Tse Fung Ping Leung Wing Tak Wong School of Life Sciences Faculty of ScienceThe Chinese University of Hong KongShatinNTHong Kong SAR State Key Laboratory of Agrobiotechnology The Chinese University of Hong KongHong KongChina

Cardiovascular disease is a major cause of mortality in diabetic patients due to the heightened oxidative stress and pro-inflammatory state in vascular *** approaches targeting cardiovascular health for diabetic patients are urgently *** blood,an emerging dietary supplement,was suggested to have anti-oxidative and anti-inflammatory effects in vitro,which have yet to be proven in animal *** study thereby aimed to evaluate whether crocodile blood can protect vascular function in diabetic mice against oxidation and *** db/db mice and their counterparts db/m+mice were treated daily with crocodile blood soluble fraction(CBSF)or vehicle via oral gavage for 4 weeks before their aortae were harvested for endothelium-dependent relaxation(EDR)quantification using wire myograph,which is a well-established functional study for vascular function *** culture experiments culturing mouse aortae from C57BL/6 J mice with or without IL-1βand CBSF were done to evaluate the direct effect of CBSF on endothelial *** oxygen species(ROS)levels in mouse aortae were assessed by dihydroethidium(DHE)staining with inflammatory markers in endothelial cells quantified by quantitative polymerase chain reaction(qPCR).CBSF significantly improved deteriorated EDR in db/db diabetic mice through both diet supplementation and direct culture,with suppression of ROS level in mouse *** also maintained EDR and reduced ROS levels in mouse aortae against the presence of pro-inflammatory IL-1β.Under the pro-inflammatory state induced by IL-1β,gene expressions of inflammatory cytokines were downregulated,while the protective transcripts UCP2 and SIRT6 were upregulated in endothelial *** study suggests a novel beneficial effect of crocodile blood on vascular function in diabetic mice and that supplementation of diet with crocodile blood may act as a complementary approach to protect against vascular diseases through anti

关键词： Crocodile blood Diabetes mellitus Vascular endothelial function Anti-oxidative Anti-inflammatory