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Solitary seminal vesicle metastasis from ileal adenocarcinoma presenting with hematospermia:A case report

World Journal of Clinical Cases 2021年第23期9卷 6775-6780页

作者： Xiao-Bao Cheng Zhen-Quan Lu Wayne Lam ming-kwong yiu Ji-Shi Li Department of Surgery The University of Hong Kong-Shenzhen HospitalShenzhen 518053Guangdong ProvinceChina Division of Urology Department of SurgeryQueen Mary HospitalThe University of Hong KongHong KongChina Department of Oncology The University of Hong Kong-Shenzhen HospitalShenzhen 518053Guangdong ProvinceChina

BACKGROUND Although metastatic adenocarcinoma of the ileum is not uncommon,solitary metastasis to the seminal vesicle has not been *** report a patient with recurrent hematospermia diagnosed with metastasis to the seminal vesicle following ileal adenocarcinoma resection,his subsequent management and *** SUMMARY A 46-year-old man presented with recurrent episodes of painless *** was not associated with any lower urinary tract *** had a past medical history of ileal tumor at the terminal ileum with solitary mesenteric lymph node metastasis on presentation,and underwent partial ileectomy and lymphadenectomy 4 years *** investigations included positronemission tomography and computed tomography imaging confirmed the very unusual diagnosis of a solitary tumor at the left seminal *** leftsided vesiculectomy was carried *** analysis with immunohistochemistry showed that CDX-2 was positive and CK7 was negative,and the appearance was consistent with the diagnosis of recurrent metastatic adenocarcinoma of his previously treated intestine *** patient had an uneventful post-operative *** received adjuvant chemoradiotherapy following *** remained asymptomatic until he developed multiple bone and pulmonary metastases one year after *** Clinicians should be aware of hematospermia as the first symptom of metastatic recurrence in patients with a history of ileal adenocarcinoma.

关键词： Seminal vesicle Metastasis Ileal adenocarcinoma Hematospermia Laparoscopic vesiculectomy Case report

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Isolated penile urethral injury:A rare case following male coital trauma

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Asian Journal of Urology 2015年第3期2卷 175-178页

作者： Ka Wing Wong Brian Sze Ho Ho Chi Ho Ip ming kwong yiu Division of Urology Department of SurgeryUniversity of Hong KongPokfulamHong KongChina

Penile fractures are an uncommon urological ***,penile fractures involve the corpus cavernosum and are sometimes associated with urethral *** corpus spongiosum and urethral injuries without concomitant corpus cavernosum injury are,however,*** proper knowledge of the management of penile fractures and urethral injuries,this distinct entity can be diagnosed,assessed and managed successfully without complications.

关键词： Penile fracture Urethral injury Penis Corpus spongiosum Urological trauma Urethroplasty

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Prostate cancer detection upon transrectal ultrasound-guided biopsy in relation to digital rectal examination and prostate-specific antigen level： what to expect in the Chinese population？

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Asian Journal of Andrology 2015年第5期17卷 821-825,I0010页

作者： Jeremy YC Teoh Steffi KK Yuen James HL Tsu Charles KW Wong Brian SH Ho Ada TL Ng Wai-Kit Ma Kwan-Lun Ho ming-kwong yiu Department of Surgery Division of Urology Queen Mary Hospital University of Hong Kong Hong Kong China

We investigated the prostate cancer detection rates upon transrectal ultrasound （TRUS）-guided biopsy in relation to digital rectal examination （DRE） and prostate-specific antigen （PSA）, and risk factors of prostate cancer detection in the Chinese population. Data from all consecutive Chinese men who underwent first TRUS-guided prostate biopsy from year 2000 to 2013 was retrieved from our database. The prostate cancer detection rates with reference to DRE finding and PSA level of 〈 4, 4-10, 10.1-20, 20.1-50 and 〉 50 ng ml^-1 were investigated. Multivariate logistic regression analyses were performed to investigate for potential risk factors of prostate cancer detection. A total of 2606 Chinese men were included. In patients with normal DRE, the cancer detection rates were 8.6%, 13.4%, 21.8%, 41.7% and 85.2% in patients with PSA 〈 4, 4-10, 10.1-20, 20.1-50 and 〉 50 ng ml^-1 respectively. In patients with abnormal DRE, the cancer detection rates were 12.4%, 30.2%, 52.7%, 80.6% and 96.4% in patients with PSA 〈 4, 4-10, 10.1-20, 20.1-50 and 〉 50 ng m1-1 respectively. Older age, smaller prostate volume, larger number of biopsy cores, presence of abnormal DRE finding and higher PSA level were associated with increased risk of prostate cancer detection upon multivariate logistic regression analyses （P 〈 0.001）. Chinese men appeared to have lower prostate cancer detection rates when compared to the Western population. Taking the different risk factors into account, an individualized approach to the decision of TRUS-guided biopsy can be adopted.

关键词： Chinese digital rectal examination prostate biopsy prostate cancer prostate-specific antigen

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The performance characteristics of prostate-specific antigen and prostate-specific antigen density in Chinese men

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Asian Journal of Andrology 2017年第1期19卷 113-116页

作者： Jeremv YC Teoh Steffi KK Yuen James HL Tsu Charles KW Wong Brian SH Ho Ada TL Ng Wai-Kit Ma Kwan-Lun Ho ming-kwong yiu Division of Urology Department of Surgery Queen Mary Hospital University of Hong Kong Hong Kong China

We investigated the performance characteristics of prostate-specific antigen （PSA） and PSA density （PSAD） in Chinese men. All Chinese men who underwent transrectal ultrasound-guided prostate biopsy （TRUS-PB） from year 2000 to 2013 were included. The receiver operating characteristic （ROC） curves for both PSA and PSAD were analyzed. The sensitivity, specificity, positive predictive value （PPV） and negative predictive value （NPV） at different cut-off levels were calculated. A total of 2606 Chinese men were included. For the ROC, the area under curve was 0.770 for PSA （P〈 0.001） and 0.823 for PSAD （P〈 0.001）. PSA of 4.5 ng ml^-1 had sensitivity of 94.4%, specificity of 14.1%, PPV of 29.5%, and NPV of 86.9%; PSAD of 0.12 ng ml^-1cc^-1 had sensitivity of 94.5%, specificity of 26.6%, PPV of 32.8%, and NPV of 92.7%. On multivariate logistic regression analyses, PSA cut-off at 4.5 ng ml^-1 （OR 1.61, 95% CI 1.05-2.45, P = 0.029） and PSAD cut-off at 0.12 ng ml^-1 cc^-1 （OR 6.22, 95% CI 4.20-9.22, P 〈 0.001） were significant predictors for prostate cancer detection on TRUS-PB. In conclusion, the performances of PSA and PSAD at different cut-off levels in Chinese men were very different from those in Caucasians. PSA of 4.5 ng ml^-1 and PSAD of O. 12 ng ml^-1 cc^-1 had near 95% sensitivity and were significant predictors of prostate cancer detection in Chinese men.

关键词： Chinese prostate cancer transrectal ultrasound-guided prostate biopsy prostate-specific antigen prostate-specific antigen density

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Association of time to prostate-specific antigen nadir and logarithm of prostate-specific antigen velocity after progression in metastatic prostate cancer with prior primary androgen deprivation therapy

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Asian Journal of Andrology 2017年第1期19卷 98-102页

作者： Jeremy YC Teoh James HL Tsu Steffi KK Yuen Peter KF Chiu Samson YS Chan Ka-Wing Wong Kwan-Lun Ho Simon SM Hou Chi-Fai Ng ming-kwong yiu Division of Urology Department of Surgery The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong China Division of Urology Department of Surgery Queen Mary Hospital University of Hong Kong Hong Kong China.

We investigated the association of time to prostate-specific antigen nadir （TTPN） and logarithm of prostate-specific antigen velocity after progression Log（PSAVAP） in metastatic prostate cancer with prior primary androgen deprivation therapy （ADT）. All metastatic prostate cancer patients treated with primary ADT from 2000 to 2009 were reviewed. Patients who developed disease progression were included in the subsequent analyses. Patients were categorized into three groups according to their TTPN： TTPN of 〈3 months, 3-17 months, and 〉17 months. We compared the Log（PSAVAP） between the different TTPN groups using Mann-Whitney U-test and Kruskal-Wallis test. Further multiple linear regression analyses on Log（PSAVAP） were performed to adjust for other potential confounding factors. Among 419 patients who were treated with primary ADT, 306 patients developed disease progression with a median follow-up of 28 months, Longer TTPN was associated with lower Log（PSAVAP）（P = 0.008） within all subgroup analyses （TTPN of 〈3 vs 3-17 months, P = 0.020; TTPN of 3-17 vs 〉17 months, P = 0.009; and TTPN of 〈3 vs 〉17 months, P = 0.001）. Upon multiple linear regression analyses, baseline PSA （regression coefficient 0.001, P = 0.045）, PSA nadir （regression coefficient 0.002, P = 0.040）, and TTPN （regression coefficient -0.030, P = 0.001） were the three factors that were significantly associated with Log（PSAVAP）. In conclusion, a longer TTPN was associated with lower Log（PSAVAP） in metastatic prostate cancer patients following primary ADT. TTPN cut-offs at 3 months and 17 months appeared to have prognostic significance in predicting Log（PSAVAP）. TTPN may serve as a good prognostic indicator in deciding the treatment strategy in patients with disease progression.

关键词： androgen deprivation therapy prostate cancer prostate-specific antigen velocity after progression ti me to prostate-specific antigen nadir

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Multiparametric magnetic resonance imaging/transrectal ultrasound fusion prostate biopsy with semi-robotic navigation in the Chinese population： initial results

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Asian Journal of Andrology 2018年第1期20卷 93-94页

作者： Wai Kit Ma Brian SH HO Andrew SH Lai Ka Cheong Lam Yun Sang Chan Lawrance KC Yip Ada TL Ng James HL Tsu ming kwong yiu Division of Urology Department of Surgery The University of Hong Kong Queen Mary Hospital Hong Kong China Department of Diagnostic Radiology The University of Hong Kong Queen Mary Hospital Hong Kong China

Dear Editor, The current standard 12-core systematic transrectal ultrasound （TRUS）-guided biopsy in prostate cancer diagnosis has the disadvantages of overdetecting indolent tumors, while failing to identify clinically significant cancers in up to 35%.1 Advances in imaging techniques, notably the multiparametric magnetic resonance imaging （mpMRI）, allow clinically significant prostate cancers to be detected with more precise localization） Fusion of MRI and real-time TRUS enables targeted biopsy of suspicious lesions, overcoming human error, and inability of biopsy site tracking in cognitive fusion？ Multiple Western series have suggested a higher detection rate, higher specificity, and better risk stratification with fusion biopsy.

关键词： magnetic resonance imaging cancer diagnosis

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Anterior perineal hernia after anterior exenteration

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Asian Journal of Urology 2017年第4期4卷 253-255页

作者： Ka Wing Wong Terence Chun-ting Lai Ada Tsui-lin Ng Brian Sze-ho Ho James Hok-leung Tsu Chiu Fung Tsang W.K.Ma ming kwong yiu Division of Urology Department of SurgeryQueen Mary HospitalUniversity of Hong KongHong KongChina

Perineal hernia is a rare complication of anterior *** reported this complication after an anterior exenteration for bladder cancer with bleeding complication requiring packing and second-look *** approach is a simple... 详细信息

关键词： Perineal hernia Anterior exenteration Bladder cancer Mesh repair

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k-Dimensional hashing scheme for hard disk integrity verification in computer forensics

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Journal of Zhejiang University-Science C(Computers and Electronics) 2011年第10期12卷 809-818页

作者： Zoe Lin JIANG Lucas Chi kwong HUI Siu ming yiu Kam Pui CHOW School of Computer Science and Technology Harbin Institute of Technology Shenzhen Graduate School Department of Computer Science The University of Hong Kong

Verifying the integrity of a hard disk is an important concern in computer forensics,as the law enforcement party needs to confirm that the data inside the hard disk have not been modified during the investigation.A typical approach is to compute a single chained hash value of all sectors in a specific ***,this technique loses the integrity of all other sectors even if only one of the sectors becomes a bad sector occasionally or is modified *** this paper we propose a k-dimensional hashing scheme,kD for short,to distribute sectors into a kD space,and to calculate multiple hash values for sectors in k dimensions as integrity *** the integrity of the sectors can be verified depending on any hash value calculated using the sectors,the probability to verify the integrity of unchanged sectors can be high even with bad/modified sectors in the hard *** show how to efficiently implement this kD hashing scheme such that the storage of hash values can be reduced while increasing the chance of an unaffected sector to be verified *** results of a 3D scheme show that both the time for computing the hash values and the storage for the hash values are reasonable.

关键词： Computer forensics Digital evidence Hard disk integrity k-Dimensional hashing

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Video color conceptualization using optimization

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Science China(Information Sciences) 2014年第7期57卷 173-183页

作者： CAO XiaoChun ZHANG YuJie GUO XiaoJie CHEUNG yiu-ming School of Computer Science and Technology Tianjin University Department of Computer Science Hong Kong Baptist UniversityHong Kong SARHong Kong 999077China

Color conceptualization aims to propagate"color concepts"from a library of natural color images to the input image by changing the main ***,the existing method may lead to spatial discontinuities in images because of the absence of a spatial consistency *** this paper,to solve this problem,we present a novel method to force neighboring pixels with similar intensities to have similar *** this constraint,the color conceptualization is formalized as an optimization problem with a quadratic cost ***,we further expand two-dimensional(still image)color conceptualization to three-dimensional(video),and use the information of neighboring pixels in both space and time to improve the consistency between neighboring *** performance of our proposed method is demonstrated for a variety of images and video sequences.

关键词： color conceptualization color discontinuity optimization color correspondence video sequence

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A Survey of Human Action Recognition and Posture Prediction

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Tsinghua Science and Technology 2022年第6期27卷 973-1001页

作者： Nan Ma Zhixuan Wu yiu-ming Cheung Yuchen Guo Yue Gao Jiahong Li Beiyan Jiang Beijing Key Laboratory of Information Service Engineering the College of RoboticsBeijing Union UniversityBeijing 100101China Department of Computer Science Hong Kong Baptist UniversityHong Kong 999077China Beijing National Research Center for Information Science and Technology Tsinghua UniversityBeijing 100084China School of Software Tsinghua UniversityBeijing 100084China College of Robotics Beijing Union UniversityBeijing 100101China

Human action recognition and posture prediction aim to recognize and predict respectively the action and postures of persons in *** are both active research topics in computer vision community,which have attracted considerable attention from academia and *** are also the precondition for intelligent interaction and human-computer cooperation,and they help the machine perceive the external *** the past decade,tremendous progress has been made in the field,especially after the emergence of deep learning ***,it is necessary to make a comprehensive review of recent *** this paper,firstly,we attempt to present the background,and then discuss research ***,we introduce datasets,various typical feature representation methods,and explore advanced human action recognition and posture prediction ***,facing the challenges in the field,this paper puts forward the research focus,and introduces the importance of action recognition and posture prediction by taking interactive cognition in self-driving vehicle as an example.

关键词： human action recognition posture prediction computer vision human-computer cooperation interactive cognition

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