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Deeply functional identification of TCS1 alleles provides efficient technical paths for low-caffeine breeding of tea plants

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Horticulture Research 2023年第2期10卷 266-274页

作者： Yi Wang Yu-Fei Liu Meng-Yuan Wei Chen-Yu Zhang Jie-Dan Chen ming-zhe yao Liang Chen Ji-Qiang Jin Key Laboratory of Biology Genetics and Breeding of Special Economic Animals and PlantsMinistry of Agriculture and Rural AffairsTea Research Institute of the Chinese Academy of Agricultural SciencesHangzhou 310008China Yunnan Provincial Key Laboratory of Tea Science Tea Research InstituteYunnan Academy of Agricultural Sciences2 Jingnan RoadMenghaiYunnan 666201China

Caffeine is an important functional component in tea,which has the effect of excitement and nerve stimulation,but excessive intake can cause insomnia and ***,the production of tea with low-caffeine content can meet the consumption needs of certain ***,in addition to the previous alleles of the tea caffeine synthase(TCS1)gene,a new allele(TCS1h)from tea germplasms was *** of in vitro activity analysis showed that TCS1h had both theobromine synthase(TS)and caffeine synthase(CS)***-directed mutagenesis experiments of TCS1a,TCS1c,and TCS1h demonstrated that apart from the 225th amino acid residue,the 269th amino acid also determined the CS *** histochemical analysis and dual-luciferase assay indicated the low promoter activity of TCS1e and *** parallel,insertion and deletion mutations in large fragments of alleles and experiments of site-directed mutagenesis identified a key cis-acting element(G-box).Furthermore,it was found that the contents of purine alkaloids were related to the expression of corresponding functional genes and alleles,and the absence or presence and level of gene expression determined the content of purine alkaloids in tea plants to a certain *** summary,we concluded TCS1 alleles into three types with different functions and proposed a strategy to effectively enhance low-caffeine tea germplasms in breeding *** research provided an applicable technical avenue for accelerating the cultivation of specific low-caffeine tea plants.

关键词： functional alkaloids directed

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Nanodiamond/Ti_(3)C_(2) MXene-coated quartz crystal microbalance humidity sensor with high sensitivity and high quality factor

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Rare Metals 2024年第6期43卷 2719-2729页

作者： yao yao Qiao Chen Yan-Qi Li Xian-He Huang Wei-Wei Ling zhe-MiaoXie Jia-QiWang Chang-ming Chen College of Communication Engineering Chengdu University of Information TechnologyChengdu 610225China School of Automation Chongqing University of Posts and TelecommunicationsChongqing 400065China School of Automation Engineering University of Electronic Science and Technology of ChinaChengdu 611731China Advanced Micro-/Nano-Devices Lab Department of Systems Design EngineeringUniversity of WaterlooWaterlooON N2L 3GlCanada

To address the challenge of achieving both high sensitivity and a high quality factor in quartz crystal microbalance(QCM)humidity sensors,a nanodiamond(ND)/Ti_(3)C_(2)MXene composite-coated QCM humidity sensor was *** material characteristics of ND,Ti_(3)C_(2)MXene,and ND/Ti_(3)C_(2)MXene composite were analyzed by transmission electron microscopy(TEM)and Fourier transform infrared(FTIR)*** experimental results demonstrated that the hydrophilic ND nanoparticles coated on Ti_(3)C_(2) MXene nanosheet prevented the self-stacking of Ti_(3)C_(2)MXene and enhanced the sensitivity of Ti_(3)C_(2) MXene-based QCM humidity ***,the high mechanical modulus of Ti_(3)C_(2) MXene material helped ND/Ti_(3)C_(2)MXene composite-coated QCM humidity sensor to achieve a high quality factor(>20,000).ND/Ti_(3)C_(2)MXene compositecoated QCM humidity sensor exhibited a sensitivity of 82.45 Hz/%RH,a humidity hysteresis of 1.1%RH,fast response/recovery times,acceptable repeatability,and good stability from 11.3%RH to 97.3%*** response mechanism of ND/Ti_(3)C_(2) MXene composite-coated QCM humidity sensor was analyzed in combination with a bi-exponential kinetic adsorption ***,the potential application of ND/Ti_(3)C_(2)MXene composite-coated QCM humidity sensor was demonstrated through its frequency response to wooden blocks with different moisture contents.

关键词： Humidity sensor Quartz crystal microbalance Nanodiamond Ti_(3)C_(2)MXene High quality factor

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Aircraft parameter estimation using a stacked long short-term memory network and Levenberg-Marquardt method

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Chinese Journal of Aeronautics 2024年第2期37卷 123-136页

作者： zhe HUI Yinan KONG Weigang yao Gang CHEN School of Aerospace Science and Technology Xidian UniversityXi’an 710071China Computation Aerodynamics Institution China Aerodynamics Research and Development CenterMianyang 621000China Faculty of Computing Engineering and MediaDe Montfort UniversityLeicester LE19BHUnited Kingdom School of Aerospace Engineering Xi’an Jiaotong UniversityXi’an 710049China

To effectively estimate the unknown aerodynamic parameters from the aircraft’s flight data,this paper proposes a novel aerodynamic parameter estimation method incorporating a stacked Long Short-Term Memory(LSTM)network model and the Levenberg-Marquardt(LM)*** stacked LSTM network model was designed to realize the aircraft dynamics modeling by utilizing a frame of nonlinear functional mapping based entirely on the measured input-output data of the aircraft system without requiring explicit postulation of the *** LM method combines the already-trained LSTM network model to optimize the unknown aerodynamic *** proposed method is applied by using the real flight data,generated by ATTAS aircraft and a bio-inspired morphing Unmanned Aerial Vehicle(UAV).The investigation reveals that for the two different flight data,the designed stacked LSTM network structure can maintain the efficacy of the network prediction capability only by appropriately adjusting the dropout rates of its hidden layers without changing other network parameters(i.e.,the initial weights,initial biases,number of hidden cells,time-steps,learning rate,and number of training iterations).Besides,the proposed method’s effectiveness and potential are demonstrated by comparing the estimated results of the ATTAS aircraft or the bio-inspired morphing UAV with the corresponding reference values or wind-tunnel results.

关键词： Parameter estimation LSTM network model LM method Aerodynamic parameters Flight data Aircraft dynamics modeling Network prediction capability Network parameters

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The role of inflammasomes in human diseases and their potential as therapeutic targets

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Signal Transduction and Targeted Therapy 2024年第2期9卷 479-508页

作者： Jing yao Keenan Sterling zhe Wang Yun Zhang Weihong Song The National Clinical Research Center for Geriatric Disease Xuanwu HospitalCapital Medical UniversityBeijing 100053China Townsend Family Laboratories Department of PsychiatryBrain Research CenterThe University of British Columbia2255 Wesbrook MallVancouverBC V6T 1Z3Canada Key Laboratory of Neurodegenerative Diseases Ministry of EducationBeijingP.R.China zhejiang Clinical Research Center for Mental Disorders Key Laboratory of Alzheimer’s Disease of Zhejiang ProvinceSchool of Mental Health and The Affiliated Kangning HospitalInstitute of AgingWenzhou Medical UniversityWenzhouZhejiang 325000China Oujiang Laboratory(zhejiang Lab for Regenerative Medicine Vision and Brain Health)WenzhouZhejiang 325000China

Inflammasomes are large protein complexes that play a major role in sensing inflammatory signals and triggering the innate immune *** inflammasome complex has three major components:an upstream sensor molecule that is connected to a downstream effector protein such as caspase-1 through the adapter protein *** formation typically occurs in response to infectious agents or cellular *** active inflammasome then triggers caspase-1 activation,followed by the secretion of pro-inflammatory cytokines and pyroptotic cell *** inflammasome activation and activity contribute to the development of diabetes,cancer,and several cardiovascular and neurodegenerative *** a result,recent research has increasingly focused on investigating the mechanisms that regulate inflammasome assembly and activation,as well as the potential of targeting inflammasomes to treat various *** clinical trials are currently underway to evaluate the therapeutic potential of several distinct inflammasome-targeting ***,understanding how different inflammasomes contribute to disease pathology may have significant implications for developing novel therapeutic *** this article,we provide a summary of the biological and pathological roles of inflammasomes in health and *** also highlight key evidence that suggests targeting inflammasomes could be a novel strategy for developing new disease-modifying therapies that may be effective in several conditions.

关键词： inflam therapeutic potential

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Investigating effect of coke porosity on blast furnace performance based on multi-physical fields

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Journal of Iron and Steel Research(International) 2024年第2期31卷 357-367页

作者： Ji Chen Zhao Lei zhe yao Li Wang Qiang Ling Ping Cui Anhui Province Key Laboratory of Coal Clean Conversion and High Valued Utilization School of Chemistry and Chemical EngineeringAnhui University of TechnologyMa’anshan243002AnhuiChina Shanxi Academy of Printing Technology Research Institute Co. Ltd.Xi’an710077ShaanxiChina

Reducing coke use is an effective measure to reduce carbon emission and energy consumption in the blast furnace(BF)***,BF is a high-temperature moving bed reactor,where complex physical transformations coupled with complicated reactions *** makes it challenging to investigate the factors determining BF performance with the conventional method.A multi-physical field coupling mathematical model of BF was thus developed to describe its mass and heat transfer as well as its intrinsic ***,the proposed model was validated with the production *** coupling conditions,influences of dominating reactions on BF performance(temperature distribution,gas distribution,iron formation reaction,and direct reduction degree)were *** results indicated that coke combustion,indirect reduction,and direct reduction of iron ore mainly took place nearby the shaft tuyere,cohesive zone,and dripping zone,***,the rate of coke solution loss reaction was increased with the rising coke porosity in the cohesive *** the effect of coke porosity on the efficiency and stability of BF,the coke porosity of 0.42 was regarded as a reasonable value.

关键词： Blast furnace Mathematical model Multi-physical field Simulation Coke porosity

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Flexible MXene/sodium alginate composite fabric with high structural stability and oxidation resistance for electromagnetic interference shielding

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Nano Research 2024年第6期17卷 5326-5335页

作者： Hao-Wen Zhang Lu-yao Yang Meng-Lin Huang ming-Hua Cheng zhe-Sheng Feng Fanbin Meng Zifeng Lin Yan Wang School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 610054China Laboratory of Advanced Technologies of Materials(Ministry of Education) School of Materials Science and EngineeringSouthwest Jiaotong UniversityChengdu 610031China College of Materials Science and Engineering Sichuan UniversityChengdu 610065China

Wearable electromagnetic interference(EMI)shielding fabrics with excellent electromagnetic shielding performance,oxidation resistance,and structural stability are highly demanded for the rapid development of electronic devices and wireless *** are metallic conductive materials with exceptional EMI shielding properties,but they are prone to oxidation in air and have poor structural stability and durability on fabric ***,we present a one-step assembly method to fabricate fabrics coated with MXenes and polymeric sodium alginate(SA)composite(MXene-SA).SA protects MXenes from oxidation and forms a stable interlayer structure by bonding to *** MXene-SA coated fabrics are breathable and flexible,and have a low sheet resistance of 2.12±0.08Ω/sq and a high EMI shielding performance of 37.05 dB at X-band,which is comparable to the best 42.31 ***,the MXene-SA coated fabrics exhibit high structural stability and oxidation resistance under various conditions of sonication disintegration,mechanical abuse,chemical corrosion,and humidity,compared to pure MXenes coated *** believe that the wearable and high-performance MXene-SA fabrics have great potential for the next generation of ultra-portable and wearable EMI shielding products.

关键词： MXenes electromagnetic interference shielding fabric one-step assembly

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Study on a probabilistic algorithm for the forming and 3D characterization of special-shaped surfaces under profile grinding

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Advances in Manufacturing 2024年第2期12卷 288-299页

作者： Zhao-Qing Zhang Kai-Ning Shi yao-yao Shi Yi-Hui Song zhe He Ya-Song Pu School of Mechanical Engineering Northwestern Polytechnical UniversityXi’an710072People’s Republic of China Key Laboratory of High Performance Manufacturing for Aero Engine(Northwestern Polytechnical University) Ministry of Industry and Information TechnologyXi’an710072People’s Republic of China Engineering Research Center of Advanced Manufacturing Technology for Aero Engine(Northwestern Polytechnical University) Ministry of EducationXi’an710072People’s Republic of China

Profile grinding is the most crucial method for the ultra-precision machining of special-shaped ***,profile grinding produces a unique machining profile,and many random factors in the machining process lead to complex surface *** this study,the structural and probabilistic characteristics of the profile grinding of a special-shaped surface were analyzed,and a probabilistic algorithm for the forming and 3D characterization of special-shaped surfaces under profile grinding was *** forming process of a GH738 blade tenon tooth surface was considered as an example to demonstrate the *** comparison results showed that the simulation results had similar surface characteristics to the measurement results,and the relative error range of the 3D roughness parameter was 0.21%–19.76%,indicating an accurate prediction and characterization of the complex special-shaped surface under the action of multiple factors.

关键词： Special-shaped surface Profile grinding Surface morphology 3D characterization

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Uniqueness on Difference Operators of Meromorphic Functions of Infinite Order

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Acta Mathematica Sinica,English Series 2024年第2期40卷 511-527页

作者： Hui LI ming Liang FANG Xiao yao School of Science China University of Mining and TechnologyBeijing 100083P.R.China Institute of Mathematics Academy of Mathematics and System SciencesChinese Academy of SciencesBeijing 100190P.R.China School of Sciences Hangzhou Dianzi UniversityHangzhou 310012P.R.China School of Mathematical sciences and LPMC Nankai UniversityTianjin 300071P.R.China

We investigate the uniqueness problems of meromorphic functions and their difference operators by using a new *** is proved that if a non-constant meromorphic function f shares a non-zero constant and ∞ counting multiplicities with its difference operators Δcf(z) and Δ_(c)^(2)f(z), thenΔcf(z)≡Δ_(c)^(2)f(z).In particular,we give a difference analogue of a result of *** method has two distinct features:(ⅰ) It converts the relations between functions into the corresponding *** makes it possible to deal with the uniqueness problem by linear algebra and combinatorics.(ⅱ) It circumvents the obstacle of the difference logarithmic derivative lemma for meromorphic functions of infinite order,since this method does not depend on the growth of the ***,the idea in this paper can also be applied to the case for several variables.

关键词： Uniqueness meromorphic functions difference operators infinite order

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Experimental and numerical study on protective effect of RC blast wall against air shock wave

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Defence Technology（防务技术） 2024年第1期31卷 567-579页

作者： Xin-zhe Nian Quan-min Xie Xin-li Kong Ying-kang yao Kui Huang State Key Laboratory of Precision Blasting Jianghan UniversityWuhan430056China Hubei Key Laboratory of Blasting Engineering Jianghan UniversityWuhan430056China Hubei(Wuhan)Institute of Explosion and Blasting Technology Jianghan UniversityWuhan430056China College of Defense Engineering Army Engineering University of PLANanjing210007China Institute of Defense Engineering AMSPLALuoyang471023China

Prototype experiments were carried out on the explosion-proof performance of the RC blast *** mass of TNT detonated in the experiments is 5 kg and 20 kg *** shock wave overpressure was tested in different *** above experiments were numerically simulated,and the simulated shock wave overpressure waveforms were compared with that tested and given by CONWEP *** results show that the numerically simulated waveform is slightly different from the test waveform,but similar to CONWEP *** dimensional analysis and numerical simulation under different working conditions,the equation for the attenuation rate of the diffraction overpressure behind the blast wall was *** to the corresponding standards,the degree of casualties and the damage degree of the brick concrete building at a certain distance behind the wall can be determined when parameters are *** above results can provide a reference for the design and construction of the reinforced concrete blast wall.

关键词： Blast wall Shock wave Diffraction Overpressure Protection

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Manufacturing task data chain-driven production logistics trajectory analysis and optimization decision making method

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Advances in Manufacturing 2024年第1期12卷 185-206页

作者： Lin Ling zhe-ming Song Xi Zhang Peng-Zhou Cao Xiao-Qiao Wang Cong-Hu Liu ming-Zhou Liu School of Mechanical Engineering Hefei University of TechnologyHefei230009People’s Republic of China Guobo Electronics Co.Ltd. Nanjing211111People’s Republic of China School of Mechanical and Electronic Engineering Suzhou UniversitySuzhou234000AnhuiPeople’s Republic of China Sino-US Global Logistics Institute Shanghai Jiao Tong UniversityShanghai200030People’s Republic of China

Production logistics(PL)is considered as a critical factor that affects the efficiency and cost of production operations in discrete manufacturing *** effectively utilize manufacturing big data to improve PL efficiency and promote job shop floor economic benefits,this study proposes a PL trajectory analysis and optimization decision making method driven by a manufacturing task data chain(MTDC).First,the manufacturing task chain(MTC)is defined to characterize the discrete production process of a *** handle manufacturing big data,the MTC data paradigm is designed,and the MTDC is ***,the logistics trajectory model is presented,where the various types of logistics trajectories are extracted using the MTC as the search engine for the *** on this,a logistics efficiency evaluation indicator system is proposed to support the optimization decision making for the ***,a case study is applied to verify the proposed method,and the method determines the PL optimization decisions for PL efficiency without changing the layout and workshop equipment,which can assist managers in implementing the optimization decisions.

关键词： Production logistics(PL) Logistics trajectory analysis Logistics optimization Data driven Manufacturing task data chain(MTDC)

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