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Laparoscopic repair via the transabdominal preperitoneal procedure for bilateral lumbar hernia: Three cases report and review of literature

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World Journal of Clinical Cases 2018年第10期6卷 398-405页

作者： Di-yu Huang Long Pan ming-yu chen Jing Fang Department of General Surgery Sir Run-Run Shaw Hospital Zhejiang University Key Laboratory of Laparoscopic Technique Research of Zhejiang Province Sir Run-Run Shaw Hospital Zhejiang University

A lumbar hernia is a rare entity, and a bilateral lumbar hernia is much rarer. From May 2015 to October 2017, we treated only three patients with bilateral lumbar hernias. One patient came to the hospital presenting with right-sided abdominal pain, and the other two patients presented with bilateral lumbar masses. The previous bilateral lumbar hernia reported in the literature was repaired by open surgery. The laparoscopic approach via the transabdominal preperitoneal(TAPP) procedure with the self-gripping Parietex ProG rip? mesh was performed at our center. The laparoscopic repair was conducted by a skilled hernia surgeon, and was successfully performed in the three patients. The patients resumed a semiliquid diet and had no activity restriction after six hours following the operation. No antibiotics were used after the surgery. The operative times of the three patients were 120 min, 85 min, and 130 min. The blood loss volumes of the three patients were 20 mL, 5 mL, and 5 mL. The visual analogue scale pain scores of the three patients were 1, 2, and 2 on postoperative day 1, and were 1, 2, and 1 on postoperative day 3. No perioperative complications, such as bulge, wound infection and hematoma, occurred after the surgery. All of the patients were discharged on the third day after the operation. There was no chronic pain and no hernia recurrence during the follow-up. This study showed that the laparoscopic TAPP approach with the self-gripping mesh is safe and feasible, and can be considered an alternative method for the treatment of bilateral lumbar hernias.

关键词： Bilateral lumbar hernia Laparoscopic repair Transabdominal preperitoneal Self-gripping mesh

An efficient method for the synthesis of dialkyl chlorophosphates from trialkyl phosphites using bis(trichloromethyl)carbonate

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Chinese Chemical Letters 2008年第8期19卷 904-906页

作者： Bo Wang Chuan ming yu Zhi Wei chen Wei Ke Su College of Pharmaceutical Sciences Zhejiang University of Technology Zhejiang Key Laboratory of Pharmaceutical Engineering Hangzhou 310014 China

A mild and simple method for the synthesis of dialkyl chlorophosphates is described, bis（trichloromethyl） carbonate （BTC） is used as the effective reagent for the conversion of dialkyl phosphites to their correspo... 详细信息

关键词： Bis(trichloromethyl) carbonate Dialkyl chlorophosphate Tdalkyl phosphite Synthesis

Labeled Network Stack: A High-Concurrency and Low-Tail Latency Cloud Server Framework for Massive IoT Devices

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Journal of Computer Science & Technology 2020年第1期35卷 179-193页

作者： Wen-Li Zhang Ke Liu Yi-Fan Shen Ya-Zhu Lan Hui Song ming-yu chen yuan-Fei chen State Key Laboratory of Computer Architecture Institute of Computing TechnologyChinese Academy of Sciences Beijing 100190China University of Chinese Academy of Sciences Beijing 100049China Peng cheng Laboratory Shenzhen 518000China Zhongke Zhicheng Electronic Technology Company Limited Jining 272000China

Internet of Things(IoT)applications have massive client connections to cloud servers,and the number of networked IoT devices is remarkably *** services require both low-tail latency and high concurrency in *** study aims to determine whether an order of magnitude improvement is possible in tail latency and concurrency in mainstream systems by proposing a hardware-software codesigned labeled network stack(LNS)for future *** key innovation is a cross-layered payload labeling mechanism that distinguishes different requests by payload across the full network stack,including application,TCP/IP,and Ethernet *** type of design enables prioritized data packet processing and forwarding along the full datapath,such that latency-insensitive requests cannot significantly interfere with high-priority *** build a prototype datacenter server to evaluate the LNS design against a commercial X86 server and the mTCP research,using a cloud-supported IoT application *** results show that the LNS design can provide an order of magnitude improvement in tail latency and concurrency.A single datacenter server node can support over 2 million concurrent long-living connections for IoT devices as a 99-percentile tail latency of 50 ms is *** addition,the hardware-software codesign approach remarkably reduces the labeling and prioritization overhead and constrains the interference of high-priority requests to low-priority requests.

关键词： tail latency high concurrency network stack cloud server Internet of Things(IoT)service

Reinforcing effect of calcium sulfate cement bovine bone morphogenetic protein on vertebral in the rabbit model of osteoporosis

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Asian Pacific Journal of Tropical Medicine 2014年第5期7卷 382-385页

作者： Jie Zhang chen Sheng-Guo Kaken.Habaerxi Shawuti.Alimujiang yu chen ming-Zhen Peng Rong yue yu-Lian Wu De-Quan Wang yu-ming chen Xinjiang Autonomous Region People's Hospital Anatomy Section Xinjiang Medical University Otolaryngology Xinjiang Medical University

Objective:To observe reinforcing effect of calcium sulfate cement(CSC) bovine bone morphogenetic protein(bBMP) on vertebral in the rabbit model of ***:A total of 48 New Zealand white rabbits were randomly divided into group Ⅰ(blank control group),groupⅡ(CSC injection group),group Ⅲ(CSC/bBMP injection group) and control *** rabbit osteoporosis model was established rapidly by using castration mcthod+methylprcdnisolone *** modeling,groups Ⅱ.Ⅲ were given corresponding vertebral body injection material,and 4 animals were sacrificed respectively at 24 h,6 weeks,12 weeks after vertebral *** pathological status,vertebral mineral density and vertebral body bone mechanical strength were ***:Vertebral body structure form was normal in the groups Ⅱand Ⅲ.Trabecular bone coarsens,connection and repair were observed in micro fracture and bone defects,bone trabecular connectivity was superior to group I significantly;vertebral body compression strength in the group I was on the decline,vertebral compression strength in the groups Ⅱ and Ⅲ was on the rise,the largest *** BMC and BMD in groups Ⅱand Ⅲ were incresed,and significantly higher than group I after 6 weeks(P<0.05),BMC and BMD in group Ⅲ after 12 weeks were higher than the other three ***:Compound bBMP CSC has good bone *** can improve the three-dimensional construction effect for osteoporosis vertebral trabecula,and can significantly improve the vertebral strength,as a vertebral packing material with good application prospect.

关键词： CSC BBMP Rabbit Osteoporosis Vertebral reinforcing

IMPULP:A Hardware Approach for In-Process Memory Protection via User-Level Partitioning

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Journal of Computer Science & Technology 2020年第2期35卷 418-432页

作者： Yang-Yang Zhao ming-yu chen yu-Hang Liu Zong-Hao Yang Xiao-Jing Zhu Zong-Hui Hong yun-Ge Guo State Key Laboratory of Computer Architecture Institute of Computing TechnologyChinese Academy of Sciences Beijing 100190China University of Chinese Academy of Sciences Beijing 100049China Peng cheng Laboratory Shenzhen 518055China

In recent years many security attacks occur when malicious codes abuse in-process memory *** to the increasing complexity,an application program may call third-party code which cannot be controlled by programmers but may contain security *** a result,the users have the risk of suffering information leakage and control flow ***,current solutions like Intel memory protection extensions(MPX)severely degrade performance,while other approaches like Intel memory protection keys(MPK)lack flexibility in dividing security *** this paper,we propose IMPULP,an effective and efficient hardware approach for in-process memory *** rationale of IMPULP is user-level partitioning that user code segments are divided into different security domains according to their instruction addresses,and accessible memory spaces are specified dynamically for each domain via a set of boundary *** instruction related to memory access will be checked according to its security domain and the corresponding boundaries,and illegal in-process memory access of untrusted code segments will be *** can be leveraged to prevent a wide range of in-process memory abuse attacks,such as buffer overflows and memory *** verification,an FPGA prototype based on RISC-V instruction set architecture has been *** present eight tests to verify the effectiveness of IMPULP,including five memory protection function tests,a test to defense typical buffer overflow,a test to defense famous memory leakage attack named Heartbleed,and a test for security *** execute the SPEC CPU2006 benchmark programs to evaluate the efficiency of *** performance overhead of IMPULP is less than 0.2%runtime on average,which is ***,the resource overhead is less than 5.5%for hardware modification of IMPULP.

关键词： in-process isolation memory protection out-of-bounds user-level partitioning

Blow-up for Doubly Degenerate Nonlinear Parabolic Equations

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Acta Mathematica Sinica,English Series 2008年第9期24卷 1525-1532页

作者： ming yu chen School of Science,Quanzhou Nomal University,Quanzhou,Fujian 362000,P,R.China School of Science Quanzhou Nomal University Quanzhou Fujian 362000 P. R. China

In this paper, we give a complete picture of the blow-up criteria for weak solutions of the Dirichlet problem of some doubly degenerate nonlinear parabolic equations.

关键词： doubly degenerate parabolic equation weak solution blow up global existence first eigenvalue

Prognostic factors and predictors of postoperative adjuvant transcatheter arterial chemoembolization benefit in patients with resected hepatocellular carcinoma

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World Journal of Gastroenterology 2020年第10期26卷 1042-1055页

作者： ming-yu chen Sarun Juengpanich Jia-Hao Hu Win Topatana Jia-Sheng Cao chen-Hao Tong Jian Lin Xiu-Jun Cai Department of General Surgery Sir Run-Run Shaw HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina School of Medicine Zhejiang UniversityHangzhou 310016Zhejiang ProvinceChina Engineering Research Center of Cognitive Healthcare of Zhejiang Province Hangzhou 310000Zhejiang ProvinceChina Department of General Surgery Shaoxing People’s HospitalZhejiang UniversityShaoxing 312000Zhejiang ProvinceChina Department of General Surgery Longyou People’s HospitalQuzhou 314400Zhejiang ProvinceChina

BACKGROUND Postoperative adjuvant transcatheter arterial chemoembolization (PA-TACE) has improved overall survival (OS) in patients with hepatocellular carcinoma (HCC).However,the prognostic and predictive factors remain *** To assess the prognostic factors and the predictors of PA-TACE benefit for OS in patients with resected *** Univariate and multivariate analyses were performed to identify the potential prognostic factors for *** order to assess the predictive factors of PA-TACE benefit,the interaction variables between treatments for each subgroup were evaluated using the Cox proportional hazards regression *** A total of 378 patients (PA-TACE vs surgery alone,189:189) from three centerswere included after a propensity-score 1:1 matching *** to the group receiving surgery alone,PA-TACE prolonged the OS rate in patients with resected HCC (P <0.001).The Barcelona Clinic Liver Cancer system and ferritinto-hemoglobin ratio (FHR) were used as the prognostic factors for OS in both *** (P=0.023) and microscopic vascular invasion (MVI)(P=0.002) were also identified in the PA-TACE group,while gender (P=0.027),hepatitis B virus(P=0.034) and albumin-bilirubin grade (P=0.027) were also selected in the surgery alone *** addition,PA-TACE resulted in longer OS than surgery alone across subgroups [all hazard ratios (PA-TACE-to-surgery alone)<1].Notably,a significantly prolonged OS following PA-TACE was observed in patients with high FHR (P=0.038) and without MVI (P=0.048).CONCLUSION FHR and Barcelona Clinic Liver Cancer stages were regarded as prognostic factors for ***,high FHR and the absence of MVI were important predictive factors,which can be used to assist clinicians in selecting which patients could achieve a better OS with PA-TACE.

关键词： Postoperative adjuvant transcatheter arterial chemoembolization Hepatocellular carcinoma Prognostic factors Predictive factors Overall survival

Promising key genes associated with tumor microenvironments and prognosis of hepatocellular carcinoma

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World Journal of Gastroenterology 2020年第8期26卷 789-803页

作者： Long Pan Jing Fang ming-yu chen Shu-Ting Zhai Bin Zhang Zhi-yu Jiang Sarun Juengpanich Yi-Fan Wang Xiu-Jun Cai Key Laboratory of Laparoscopic Technique Research of Zhejiang Province Department of General SurgerySir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016Zhejiang ProvinceChina Zhejiang Province Medical Research Center of Minimally Invasive Diagnosis and Treatment of Abdominal Diseases Hangzhou 310016Zhejiang ProvinceChina

BACKGROUND Despite significant advances in multimodality treatments,hepatocellular carcinoma(HCC)remains one of the most common malignant *** of novel prognostic biomarkers and molecular targets is urgently *** To identify potential key genes associated with tumor microenvironments and the prognosis of *** The infiltration levels of immune cells and stromal cells were calculated and quantified based on the ESTIMATE *** expressed genes(DEGs)between high and low groups according to immune or stromal scores were screened using the gene expression profile of HCC patients in The Cancer Genome Atlas and were further linked to the prognosis of *** genes were validated in four independent HCC ***-related key genes were identified by a LASSO Cox regression *** HCC patients with a high immune/stromal score had better survival benefits than patients with a low score.A total of 899 DEGs were identified and found to be involved in immune responses and extracellular matrices,147 of which were associated with overall ***,52 of 147 survival-related DEGs were validated in additional ***,ten key genes(STSL2,TMC5,DOK5,RASGRP2,NLRC3,KLRB1,CD5L,CFHR3,ADH1C,and UGT2B15)were selected and used to construct a prognostic gene signature,which presented a good performance in predicting overall *** This study extracted a list of genes associated with tumor microenvironments and the prognosis of HCC,thereby providing several valuable directions for the prognostic prediction and molecular targeted therapy of HCC in the future.

关键词： Hepatocellular carcinoma Tumor microenvironment Differentially expressed genes Overall survival

Study of liver cirrhosis over ten consecutive years in Southern China

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World Journal of Gastroenterology 2014年第37期20卷 13546-13555页

作者： Xing Wang Shang-Xiong Lin Jin Tao Xiu-Qing Wei yuan-Ting Liu yu-ming chen Bin Wu Department of Gastroenterology The Third Affiliated Hos-pital of Sun Yat-sen University Statistics Room Information SectionCentral Hospital of Panyu District School of Public Health Zhongshan Medical School of Sun Yat-sen University

AIM: To investigate the etiology and complications of liver cirrhosis (LC) in Southern China.

关键词： Liver cirrhosis Epidemiology Etiology Complication Hepatocellular carcinoma Southern China