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Statistical Analysis and Evaluation of Macroeconomic Policies: A Selective Review

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Applied Mathematics(A Journal of Chinese Universities) 2020年第1期35卷 57-83页

作者： LIU Ze-qin CAI Zong-wu FANG ying LIN ming The Wang Yanan Institute for Studies in Economics MOE Key Laboratory of Econometrics(Xiamen University)Fujian Provincial Key Laboratory of Statistical ScienceXiamen UniversityXiamen 361005China Department of Economics University of KansasLawrenceKS 66045USA Department of Statistics School of EconomicsXiamen UniversityXiamen 361005China

In this paper,we highlight some recent developments of a new route to evaluate macroeconomic policy effects,which are investigated under the framework with potential ***,this paper begins with a brief introduction of the basic model setup in modern econometric analysis of program ***,primary attention goes to the focus on causal effect estimation of macroeconomic policy with single time series data together with some extensions to multiple time series ***,we examine the connection of this new approach to traditional macroeconomic models for policy analysis and ***,we conclude by addressing some possible future research directions in statistics and econometrics.

关键词： Impulse response function Macroeconomic casual inferences Macroeconomic policy evaluation Multiple time series data Potential outcomes Treatment effect.

Brain-derived neurotrophic factor plays with TRiC:focus on synaptic dysfunction in Huntington’s disease

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Neural Regeneration Research 2025年第10期20卷 2919-2920页

作者： yingli Gu Kijung Sung Chengbiao wu Department of Neurosciences University of California San DiegoLa JollaCAUSA

Brain-derived neurotrophic factor(BDNF)exerts pleiotropic effects on brain processes including psychiatric disorders,aging,neurodegeneration,and metabolic homeostasis.A simple PubMed search using the key word“BDNF,”to date,yields over 33,000 *** fundamental biology to potential therapeutic applications,BDNF has clearly garnered extensive and significant attention in the field of neurobiology research.

关键词： Huntington homeostasis therapeutic

C肽与胰岛素双标记时间分辨荧光免疫分析法的建立及初步临床应用

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生物化学与生物物理进展 2011年第7期38卷 670-676页

作者：马强李来庆贺安林冠峰邹丽萍李明吴英松南方医科大学生物技术学院抗体工程研究所广州510515 广州市达瑞抗体工程技术有限公司广州510663

建立钐(Sm3+)标记检测C肽(C-peptide)及铕(Eu3+)标记检测胰岛素(insulin)的双标记时间分辨荧光免疫分析法(TRFIA),并初步尝试检测人血C肽以及胰岛素含量.将抗C肽单克隆抗体(Biodesign No.E54094M)与抗insulin单克隆抗体(BiodesignNo.E86306M)混合包被96孔板,然后用Sm3+标记抗C肽单克隆抗体(Medix No.9103),Eu3+标记抗insulin单克隆抗体(Biodesign No.E86802M),运用双抗体夹心一步法建立C肽/胰岛素双标记时间分辨免疫荧光分析法.结果显示:C肽分析灵敏度为0.2μg/L,线性范围为0.5～22μg/L,平均回收率达到99.6%,分析内和分析间变异系数分别为4.6%～6.0%和5.1%～7.6%.胰岛素分析灵敏度为0.8 mU/L,线性范围为3.6～180 mU/L,平均回收率为99.4%,分析内和分析间变异系数分别为3.7%～6.0%和5.1%～8.0%.C肽/胰岛素双标记检测试剂与PerkinElmer公司对应的单标记进口试剂盒分别同时测定血清样本200份,检测结果高度相关,具有较好的一致性,相关系数分别为0.98与0.99.总之,自建C肽/胰岛素双标记时间分辨荧光免疫分析方法的性能均可以达到临床检测要求,有望替代现有国内外较为昂贵的单标记试剂,可用于胰岛素分泌不足导致的糖尿病诊断及糖尿病的大规模普查筛选.

关键词：双标记时间分辨荧光免疫分析 C肽胰岛素

Determination of Pesticide Residue Cartap Using a Sensitive Fluorescent Probe

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Journal of Integrative Agriculture 2012年第11期11卷 1861-1870页

作者： JING Xu DU Li-ming wu Hao wu Wen-ying CHANG Yin-xia Analytical and Testing Center Shanxi Normal University Linfen 041000 P.R.China

The insecticide cartap （CP） is non-fluorescent in aqueous solutions. This property makes its determination through direct fluorescent method difficult. In acidic medium and at room temperature, palmatine （PAL） can react with cucurbit[7]uril （CB[7]） to form stable complexes, and the fluorescence intensity of the complex is greatly enhanced. Significant quenching of the fluorescence intensity of the CB[7]-PAL complex was observed with the addition of cartap. Based on the significant quenching of the supramolecular complex fluorescence intensity, a new spectrofluorimetric method with high sensitivity and selectivity was developed to determine cartap in aqueous solution. The fluorescence quenching values （AF） showed good linear relationship with cartap concentrations from 0.009 to 2.4 ~tg mL-~ with a detection limit 0.0029 ~tg mE-x. The proposed method had been successfully applied to the determination of cartap residues in grain and vegetable with recoveries of 87.4-103%. In addition, the association constants of the complexes formed between the host and the guest were determined. The competing reaction and the supramolecular interaction mechanisms between the cartap and PAL as they fight for occupancy of the CB[7] cavity were studied using spectrofluorimetry, xH NMR and molecular modeling calculations.

关键词： cartap cucurbituril palmatine fluorescent probe

Trajectory modeling revealed a southwest-northeast migration corridor for fall armyworm Spodoptera frugiperda(Lepidoptera:Noctuidae)emerging from the North China Plain

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Insect Science 2021年第3期28卷 649-661页

作者： Qiu-Lin wu Yu-ying Jiang Jie Liu Gao Hu Kong-ming wu State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing100193China National Agro-Tech Extension and Service Centre Beijing100125China Department of Entomology Nanjing Agricultural UniversityNanjing210095China

The fall armyworm Spodoptera frugiperda,an invasive insect pest native to the Americas,has established populations throughout eastern *** North China Plain一a key corn-producing area in East China with a unique topography一was invaded by fall armyworm in 2019 and is seriously threatened by this migratory ***,the spatiotemporal extent of the migratory movements of fall armyworm from the North China Plain remains poorly *** an air transport-based trajectory modeling approach that incorporates flight behavior,we simulated the potential nocturnal migration trajectories of fall armyworm from the North China Plain based on historical meteorological data from June to October of 2015-2019,and examined the night-time atmospheric conditions associated with their possible *** emigration patterns showed monthly variation in the main landing area and common migration *** displacement of newly emerged moths from the North China Plain was concentrated in the Northeast China Plain(including Liaoning,Jilin and Heilongjiang provinces)before late summer,after which they were most likely to undertake return flights to the south(especially into Hubei,Anhui and Hunan provinces).This southwest-northeast aerial migration corridor follows the topography of East China and is affected by the East Asian *** topographic-atmospheric conditions have resulted in the North China Plain becoming a key stopover for fall armyworm populations engaging in multigenerational long-distance migration across East *** findings contribute to our knowledge of fall army-worm migration and will aid in the implementation of management and control strategies against this highly migratory agricultural pest.

关键词： atmospheric conditions fall armyworm invasive pest migration pattern North China Plain potential redistribution

Probing the weak interactions between amino acids and carbon monoxide

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Chinese Chemical Letters 2008年第1期19卷 119-122页

作者： ying wu Lin Chang ming Nie Li Fu Liao College of Chemistry and Chemical Engineering University of South China Hengyang 421001 China

The relatively weak interactions between some non-charged amino acids with CO were investigated theoretically by using density functional theory （DFT） method. The stretching frequency of CO correlates well with its bond length followed the Badger＇s rule, and the correlation between binding energy and Mulliken charge partition of CO was also investigated for the first time. 2007 ying wu Lin. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： Amino acid CO Interaction Orientation Binding energy

Comparative study of microbial community structure in different filter media of constructed wetland

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Journal of Environmental Sciences 2010年第1期22卷 127-133页

作者： ming Li Qiaohong Zhou Min Tao ying Wang Lijuan Jiang Zhenbin wu State Key Laboratory of Freshwater Ecology and Biotechnology Institute of Hydrobiology Chinese Academy of Sciences Wuhan 430072 China Graduate University of Chinese Academy of Sciences Beijing 100039 China School of Resource & Environmental Engineering Wuhan University of Technology Wuhan 430070 China

Comparisons of microbial community structure, in eight filter media of zeolites, anthracite, shale, vermiculite, ceramic filter media, gravel, steel slag and bio-ceramic, were undertaken by analyzing the phospholipid fatty acid （PLFA） composition. A total of 20 fatty acids in the range of C18to C20 were determined but only 13 PLFAs were detected in steel slag. They consist of saturated fatty acids, branched fatty acids, monounsaturated fatty acids, and polyunsaturated fatty acids. The variation of fatty acids was revealed in the relative proportions of these fatty acids in different media. The aerobic prokaryotes were the predominant group in all media. The PLFA composition showed significant differences among the eight different media by Tukey＇s honestly test. It was found that steel slag was significantly different in the microbial community as compared to other filter media, probably due to its alkaline effluent. Steel slag alone is probably not a good choice of substratum in constructed wetlands. The principle components analysis （PCA） showed that zeolites, bio-ceramic, shale and vermiculite had a similar microbial community structure while steel slag and ceramic filter media were distinct from other media.

关键词： microbial community structure phospholipid filter media biomarkers constructed wetland steel slag

Extracting copper from copper oxide ore by a zwitterionic reagent and dissolution kinetics

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International Journal of Minerals,Metallurgy and Materials 2015年第3期22卷 241-248页

作者： Jiu-shuai Deng Shu-ming Wen Jian-ying Deng Dan-dan wu State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization Faculty of Land Resource Engineering Kunming University of Science and Technology

Sulfamic acid （SA）, which possesses a zwitterionic structure, was applied as a leaching reagent for the first time for extracting copper from copper oxide ore. The effects of reaction time, temperature, particle size, reagent concentration, and stirring speed on this leach- ing were studied. The dissolution kinetics of malachite was illustrated with a three-dimensional diffusion model. A novel leaching effect of SA on malachite was eventually demonstrated. The leaching rate increased with decreasing particle size and increasing concentration, reac- tion temperature and stirring speed. The activation energy for SA leaching malachite was 33.23 kJ/mol. Furthermore, the effectiveness of SA as a new reagent for extracting copper from copper oxide ore was confirmed by experiment. This approach may provide a solution suitable for subsequent electrowinning. In addition, results reported herein may provide basic data that enable the leaching of other carbonate miner- als of copper, zinc, cobalt and so on in an SA system.

关键词： malachite copper extraction sulfamic acid dissolution kinetics

From ancient wisdom to modern science:Gut microbiota sheds light on property theory of traditional Chinese medicine

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Journal of Integrative Medicine 2024年第4期22卷 413-444页

作者： Ya-nan Yang Jia-guo Zhan ying Cao Chong-ming wu School of Chinese Materia Medica Tianjin University of Traditional Chinese MedicineTianjin 301617China Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine Tianjin 301617China

The property theory of traditional Chinese medicine(TCM) has been practiced for thousands of years,playing a pivotal role in the clinical application of TCM. While advancements in energy metabolism,chemical composition analysis, machine learning, ion current modeling, and supercritical fluid technology have provided valuable insight into how aspects of TCM property theory may be measured, these studies only capture specific aspects of TCM property theory in isolation, overlooking the holistic perspective inherent in TCM. To systematically investigate the modern interpretation of the TCM property theory from multidimensional perspectives, we consulted the Chinese Pharmacopoeia(2020 edition) to compile a list of Chinese materia medica(CMM). Then, using the Latin names of each CMM and gut microbiota as keywords, we searched the PubMed database for relevant research on gut microbiota and CMM. The regulatory patterns of different herbs on gut microbiota were then summarized from the perspectives of the four natures, the five flavors and the meridian tropism. In terms of the four natures, we found that warm-natured medicines promoted the colonization of specific beneficial bacteria,while cold-natured medicines boosted populations of some beneficial bacteria while suppressing pathogenic bacteria. Analysis of the five flavors revealed that sweet-flavored and bitter-flavored CMMs positively influenced beneficial bacteria while inhibiting harmful bacteria. CMMs with different meridian tropism exhibited complex modulative patterns on gut microbiota, with Jueyin(Liver) and Taiyin(Lung) meridian CMMs generally exerting a stronger effect. The gut microbiota may be a biological indicator for characterizing the TCM property theory, which not only enhances our understanding of classic TCM theory but also contributes to its scientific advancement and application in healthcare.

关键词： Traditional Chinese medicine Property theory Gut microbiota Four natures Five flavors Meridian tropism