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DDoS detection based on wavelet kernel support vector machine

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The Journal of China Universities of Posts and Telecommunications 2008年第3期15卷 59-63,94页

作者： yang ming-hui wang Ru-chuan College of Computer Nanjing University of Posts and Telecommunications Nanjing 210003 China

To enhance the detection accuracy and deduce false positive rate of distributed denial of service （DDoS） attack detection, a new machine learning method was proposed. With the analysis of support vector machine （SVM） and the wavelet kernel function theory, an admissive support vector kernel, which is a wavelet kernel constructed in this article, implements the combination of the wavelet technique with SVM. Then, wavelet support vector machine （WSVM） is applied to DDoS attack detections and as a classifying means to test the validity of the wavelet kernel function. Simulation experiments show that under the same conditions, the predictive ability of WSVM is improved and the computation burden is alleviated. The detection accuracy of WSVM is higher than the traditional SVM by about 4%, while its false positive is lower than the traditional SVM. Thus, for DDoS detections, WSVM shows better detection performance and is more adaptive to the changing network environment.

关键词： wavelet kernel function wavelet supporting vector machine DDoS detection

Experimental investigation on dynamic response and damage models of circular RC columns subjected to underwater explosions

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Defence Technology（防务技术） 2020年第4期16卷 856-875页

作者： Tie-shuan Zhuang ming-yang wang Jun Wu Cheng-yu yang Tao Zhang Chao Gao State Key Laboratory of Disaster Prevention and Mitigation of Explosion and Impact Army Engineering University of PLANanjing210007China Research Institute for National Defense Engineering of Academy of Military Science PLALuoyang471023China

Reinforced concrete(RC) columns are widely used as supporting structures for high-piled *** study of damage model of a RC column due to underwater explosion is a critical issue to assess the wharfs antiknock *** this study,the dynamic response and damage model of circular RC columns subjected to underwater explosions were investigated by means of scaled-down experiment *** were carried out in a 10.0 m diameter tank with the water depth of 2.25 m,under different explosive quantities(0.025 kg-1.6 kg),stand-off distances(0.0 m-7.0 m),and detonation depths(0.25 m-2.0 m).The shock wave load and dynamic response of experiment models were measured by configuring sensors of pressure,acceleration,strain,and ***,the load distribution characteristics,time history of test data,and damage models related to present conditions were obtained and *** damage models,including bending failure,bending-shear failure and punching failure,were *** addition,the experie nce model of shock wave loads on the surface of a RC column was proposed for engineering application.

关键词： Underwater explosion Reinforced concrete(RC)columns Load distribution characteristics Dynamic response Damage models

Experimental investigations of mechanical and reaction responses for drop-weight impacted energetic particles

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Acta Mechanica Sinica 2017年第1期33卷 65-70页

作者： Xiao-Wei Bao Yan-Qing Wu ming-yang wang Feng-Lei Huang State Key Laboratory of Explosion Science and Technology Beijing Institute of Technology Beijing 100081 China

Low-velocity drop-weight impact experiments on individual and multiple Cyclotetramethylene tetranitramine (HMX) energetic particles were performed using a modified drop-weight machine equipped with high-speed photography components. Multiple particles experienced more severe burning reactions than an individual particle. Comparisons between impacted salt and HMX particle show that jetting in HMX is mainly due to the motion of fragmented particles driven by gaseous reaction products. Velocity of jetting, flame propagation, and area expansion were measured via image processing, making it possible to quantify the chemical reaction or mechanical deformation violence at different stages.

关键词： HMX energetic particle Drop-weight impact High-speed photography Ignition and combustion Jetting

Pseudorabies virus manipulates mitochondrial tryptophanyl-tRNA synthetase 2 for viral replication

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Virologica Sinica 2024年第3期39卷 403-413页

作者： Xiu-Qing Li Meng-Pan Cai ming-yang wang Bo-Wen Shi Guo-Yu yang Jiang wang Bei-Bei Chu Sheng-Li ming College of Veterinary Medicine Henan Agricultural UniversityZhengzhou 450046China Key Laboratory of Animal Biochemistry and Nutrition Ministry of Agriculture and Rural AffairsZhengzhou 450046China Key Laboratory of Veterinary Biotechnology of Henan Province Henan Agricultural UniversityZhengzhou 450046China Longhu Advanced Immunization Laboratory Zhengzhou 450046China International Joint Research Center of National Animal Immunology Henan Agricultural UniversityZhengzhou 450046China Ministry of Education Key Laboratory for Animal Pathogens and Biosafety Zhengzhou 450046China School of Basic Medicine Chongqing Medical UniversityChongqing 400016China

The pseudorabies virus(PRV)is identified as a double-helical DNA virus responsible for causing Aujeszky's disease,which results in considerable economic impacts *** enzyme tryptophanyl-tRNA synthetase 2(WARS2),a mitochondrial protein involved in protein synthesis,is recognized for its broad expression and vital role in the translation *** findings of our study showed an increase in both mRNA and protein levels of WARS2 following PRV infection in both cell cultures and animal *** WARS2 expression via RNA interference in PK-15 cells led to a reduction in PRV infection rates,whereas enhancing WARS2 expression resulted in increased infection ***,the activation of WARS2 in response to PRV was found to be reliant on the cGAS/STING/TBK1/IRF3 signaling pathway and the interferon-alpha receptor-1,highlighting its regulation via the type I interferon signaling *** analysis revealed that reducing WARS2 levels hindered PRV's ability to promote protein and lipid *** research provides novel evidence that WARS2 facilitates PRV infection through its management of protein and lipid levels,presenting new avenues for developing preventative and therapeutic measures against PRV infections.

关键词： Pseudorabies virus WARS2 Innate immunity Protein synthesis Lipid synthesis

A NEW EFFICIENT ID-BASED PROXY BLIND SIGNATURE SCHEME

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Journal of Electronics(China) 2008年第2期25卷 226-231页

作者： ming yang wang Yumin State Key Lab of Integrated Service Network Xidian University Xi＇an 710071 China

In a proxy blind signature scheme,the proxy signer is allowed to generate a blind signature on behalf of the original signer. The proxy blind signature scheme is useful in several applications such as e-voting,e-payment,etc. Recently,Zheng,et al. presented an IDentity(ID) -based proxy blind sig-nature. In this paper,a new efficient ID-based proxy blind signature scheme from bilinear pairings is proposed,which can satisfy the security properties of both the proxy signatures and the blind signature schemes. Analysis of the scheme efficiency shows that the new scheme is more efficient than Zheng,et al.'s scheme. The proposed scheme is more practical in the real world.

关键词： Blind signature Proxy signature Bilinear pairing

Glutamine-supplemented total parenteral nutrition attenuates plasma interleukin-6 in surgical patients with lower disease severity

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World Journal of Gastroenterology 2005年第39期11卷 6197-6201页

作者： ming-Tsan Lin Sung-Pao Kung Sung-Ling Yeh Koung-Yi Liaw ming-yang wang ming-Liang Kuo Po-Houng Lee Wei-Jao Chen Department of Surgery and Primary Care Medicine National Talwan University Hospital and National Taiwan University College of Medicine Taipei Taiwan China Department of Surgery School of Medicine National Yang-Ming University Taipei Taiwan China Institute of Nutrition and Health Sciences Taipei Medical University Taipei Taiwan China Department of S-urgery National Taiwan University Hospital and National Taiwan University College of Medicine Taipei Taiwan China Laboratory of Molecular and Cellular Toxicology Institute of Toxicology National Taiwan University College of Medicine Taipei Taiwan China

AIM： To evaluate whether the effect of Gin dipeptideenriched total parenteral nutrition （TPN） on postoperative cytokine alteration depended on the disease severity of surgical patients. METHODS： Forty-eight patients with major abdominal surgery were allocated to two groups to receive isonitrogenous （0.228 g nitrogen/kg per d） and isocaloric （30 kcal/kg per d） TPN for 6 d. Control group （Cony） using conventional TPN solution received 1.5 g amino acids/kg per day, whereas the test group received 0.972 g amino acids/kg per day and 0.417 g L-alanyI-L-glutamine （Ala-GIn）/kg per day. Blood samples were collected on d 1 and d 6 postoperatively for plasma interleukin （IL）-2, IL-6, IL-8, and interferon （IFN）-γ analysis. RESULTS： Plasma IL-2 and IFN-γ were not detectable. IL-6 concentrations were significantly lower on the 6^th postoperative day in the Ala-GIn group than those in the Cony group in patients with APACHE Ⅱ≤6, whereas no difference was noted in patients with APACHE Ⅱ〉6. There was no difference in IL-8 levels between the two groups. No difference in cumulative nitrogen balance was observed on d 2-5 after the operation between the two groups （Ala-GIn -3.2±1.6 g vs Cony -6.5±2.7 g）. A significant inverse correlation was noted between plasma IL-6 levels and cumulative nitrogen balance postoperatively in the Ala-GIn group, whereas no such correlation was observed in the Conv group. CONCLUSION： TPN supplemented with Gin dipeptide had no effect on plasma IL-8 levels after surgery. However, Gin supplementation had a beneficial effect on decreasing systemic IL-6 production after surgery in patients with low admission illness severity, and lower plasma IL-6 may improve nitrogen balance in patients with abdominal surgery when Gin was administered.

关键词： Glutamine Total parenteral nutrition Interleukin-6 Abdominal surgery

Divergent Synthesis of Primary Amides via Modular Dearomative Carbamoylations of Areneπ-Systems

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CCS Chemistry 2024年第8期6卷 2066-2074页

作者： Chu-Qiao Li Xu Jiang ming-yang wang Wei-Long Zeng Wei Li Department of Chemistry Zhejiang UniversityHangzhou 310058

In sharp contrast to the well researched and well developed aminocarbonylation of alkenes,the dearomative carbamoylation of abundant areneπ-systems has scarcely been studied despite its great potential to enrich the diversity-oriented synthesis of high-value *** formidable challenges associated with such dearomatization include the low reactivity of stable aromaticπ-systems and intricate selectivity ***,we disclose a general approach toward highly selective dearomative carbamoylations of areneπ-bonds under CO-gas-free *** extraordinary versatility was demonstrated by tolerating a broad range of nucleophilic partners with high yields and excellent selectivities,thus providing modular access to the divergent synthesis ofβ-functionalized primary *** addition,diverse downstream derivatizations including a formal C–H 1,2-olefination/carbamoylation reaction were conducted,exhibiting great potential in synthetic and medicinal chemistry.

关键词： aminocarbonylation arene carbamoylation dearomatization primary amide

Unleashing the Potential of Electroactive Hybrid Biomaterials and Self‑Powered Systems for Bone Therapeutics

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Nano-Micro Letters 2025年第2期17卷 463-497页

作者： Shichang Liu Farid Manshaii Jinmiao Chen Xinfei wang Shaolei wang Junyi Yin ming yang Xuxu Chen Xinhua Yin Yunlei Zhou Honghui Hospital Xi’an Jiaotong UniversityXi’an 710018People’s Republic of China Department of Bioengineering Henry Samueli School of Engineering and Applied ScienceUniversity of California Los AngelesLos Angeles 90095USA Hangzhou Institute of Technology Xidian UniversityHangzhou 311231People’s Republic of China

The incidence of large bone defects caused by traumatic injury is increasing worldwide,and the tissue regeneration process requires a long recovery time due to limited self-healing *** bioelectrical phenomena have been well recognized as critical biophysical factors in bone remodeling and *** by bioelectricity,electrical stimulation has been widely considered an external intervention to induce the osteogenic lineage of cells and enhance the synthesis of the extracellular matrix,thereby accelerating bone *** ongoing advances in biomaterials and energy-harvesting techniques,electroactive biomaterials and self-powered systems have been considered biomimetic approaches to ensure functional recovery by recapitulating the natural electrophysiological microenvironment of healthy bone *** this review,we first introduce the role of bioelectricity and the endogenous electric field in bone tissue and summarize different techniques to electrically stimulate cells and ***,we highlight the latest progress in exploring electroactive hybrid biomaterials as well as self-powered systems such as triboelectric and piezoelectric-based nanogenerators and photovoltaic cell-based devices and their implementation in bone tissue ***,we emphasize the significance of simulating the target tissue’s electrophysiological microenvironment and propose the opportunities and challenges faced by electroactive hybrid biomaterials and self-powered bioelectronics for bone repair strategies.

关键词： Electroactive biomaterials Self-powered bioelectronics Bone regeneration Bone tissue

MoS_(2)Lubricate‑Toughened MXene/ANF Composites for Multifunctional Electromagnetic Interference Shielding

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Nano-Micro Letters 2025年第2期17卷 358-371页

作者： Jiaen wang Wei ming Longfu Chen Tianliang Song Moxi Yele Hao Zhang Long yang Gegen Sarula Benliang Liang Luting Yan Guangsheng wang School of Physical Science and Engineering Beijing Jiaotong UniversityBeijing 100044People’s Republic of China Key Laboratory of Bio‑Inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191People’s Republic of China

The design and fabrication of high toughness electromagnetic interference(EMI)shielding composite films with diminished reflection are an imperative task to solve electromagnetic pollution *** MXene/ANF(aramid nanofibers)–MoS_(2)composite films with nacre-like layered structure here are fabricated after the introduction of MoS_(2)into binary MXene/ANF composite *** introduction of MoS_(2)fulfills an impressive“kill three birds with one stone”improvement effect:lubrication toughening mechanical performance,reduction in secondary reflection pollution of electromagnetic wave,and improvement in the performance of photothermal *** the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 50:50),the strain to failure and tensile strength increase from 22.1±1.7%and 105.7±6.4 MPa and to 25.8±0.7%and 167.3±9.1 MPa,*** toughness elevates from 13.0±4.1 to 26.3±0.8 MJ m^(−3)(~102.3%)*** the reflection shielding effectiveness(SE_(R))of MXene/ANF(mass ratio of 50:50)decreases~10.8%.EMI shielding effectiveness(EMI SE)elevates to 41.0 dB(8.2–12.4 GHz);After the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 60:40),the strain to failure increases from 18.3±1.9%to 28.1±0.7%(~53.5%),the SE_(R)decreases~22.2%,and the corresponding EMI SE is 43.9 *** MoS_(2)also leads to a more efficient photothermal conversion performance(~45 to~55℃).Additionally,MXene/ANF–MoS_(2)composite films exhibit excellent electric heating performance,quick temperature elevation(15 s),excellent cycle stability(2,2.5,and 3 V),and long-term stability(2520 s).Combining with excellent mechanical performance with high MXene content,electric heating performance,and photothermal conversion performance,EMI shielding ternary MXene/ANF–MoS_(2)composite films could be applied in many industrial *** work broadens how to achieve a balance between mechanical properties and versatility of composites in the case of high-function fillers.

关键词： MXene-MoS_(2) Lubrication toughening EMI shielding Photothermal conversion Electric heating performance