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Endometrial carcinoma with cervical stromal invasion:Three case reports

World Journal of Clinical Cases 2024年第24期12卷 5583-5588页

作者： ming-ming liu Yu-Ting Liang Er-Hu Jin Department of Radiology Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China Department of Radiology Beijing Obstetrics and Gynecology HospitalCapital Medical UniversityBeijing Maternal and Child Health Care HospitalBeijing 100006China

BACKGROUND Endometrial cancer is a kind of well-known tumors of female genitourinary *** stromal invasion is an adverse factor for poor prognosis of endometrial *** is still controversy regarding the use of magnetic resonance imaging(MRI)in the diagnosis of cervical stromal invasion of endometrial *** diagnosis of cervical stromal invasion varies significantly between different observers and *** present a limited case series of the particular pattern of endometrial cancer,which infiltrates the cervical stroma and is often *** SUMMARY We present three cases of endometrial carcinoma with cervical stromal invasion with cancer-free uterine *** patient,a reproductive-aged woman,exhibited irregular menstruation and was diagnosed with endometrial polyps by hysteroscopy and segmental curettage.A MRI scan revealed polypoid nodules within the internal cervical *** other two cases were postmenopausal women who presented with abnormal vaginal *** and segmental curettage suggested atypical hyperplasia of the *** scans did not detect any malignant signs in the *** one case,a nonthickened endometrium was observed,while in another,hyperplasia of the endometrium was ***,none of these patients had malignant tumors identified in the uterine cavity via MRI ***,postoperative pathological results following hysterectomy consistently indicated cervical stromal *** Cervical stromal invasion is easily missed if no cancer is found in the uterine body on *** of endoscopic curettage specimens should be conducted to avoid underestimation of the disease.

关键词： Endometrial carcinoma Cervical stromal invasion Atypical hyperplasia of the endometrium Magnetic resonance imaging Case report

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Bargaining strategy of oil companies in international oil and gas development Projects-Based on a bilateral bargaining model

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Petroleum Science 2021年第4期18卷 1270-1279页

作者： Qing Xue Cheng Cheng Zhen Wang ming-ming liu School of Economics and Management China University of PetroleumBeijing102249China School of Management Science and Engineering Shanxi University of Finance and EconomicsTaiyuan030006China

Bargaining between the host country and oil companies is very common to international oil and gas development *** existence of information asymmetry gives the host country an endogenous bargaining *** oil companies might change their unfavorable negotiating position by changing the order of bidding and adjusting bidding *** paper introduces both factors into a bilateral bargaining model to study the impact of information asymmetry and bidding order on the strategy and equilibrium returns of oil *** to the ownership of the right to bid first,two scenarios are designed for the model to compare the equilibrium returns of the host country and oil *** results show that:1)There is a first-mover advantage in the process of bilateral bidding,so oil companies better bid first;2)The information asymmetry will lead to a higher nominal income ratio of oil companies and a lower nominal income ratio of the host country,but it doesn’t affect the total income ratio at all.

关键词： International oil and gas development project Information asymmetry Cooperation strategy Bilateral bidding model

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Risk measurement of international oil and gas projects based on the Value at Risk method

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Petroleum Science 2019年第1期16卷 199-216页

作者： Cheng Cheng Zhen Wang ming-ming liu Xiao-Hang Ren School of Management Science and Engineering Shanxi University of Finance and Economics Academy of Chinese Energy Strategy China University of Petroleum-Beijing School of Mathematical Sciences University of Southampton

International oil and gas projects feature high capital-intensity, high risks and contract diversity. Therefore, in order to help decision makers make more reasonable decisions under uncertainty, it is necessary to measure the risks of international oil and gas projects. For this purpose, this paper constructs a probabilistic model that is based on the traditional economic evaluation model, and introduces value at risk(VaR) which is a valuable risk measure tool in finance, and applies Va R to measure the risks of royalty contracts, production share contracts and service contracts of an international oil and gas project. Besides, this paper compares the influences of different risk factors on the net present value(NPV) of the project by using the simulation results. The results indicate:(1) risks have great impacts on the project's NPV, therefore, if risks are overlooked, the decision may be wrong.(2) A simulation method is applied to simulate the stochastic distribution of risk factors in the probabilistic model. Therefore, the probability is related to the project's NPV, overcoming the inherent limitation of the traditional economic evaluation method.(3) VaR is a straightforward risk measure tool, and can be applied to evaluate the risks of international oil and gas projects. It is helpful for decision making.

关键词： Risk measurement Value at risk International oil and gas projects Fiscal terms - Probabilistic model

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Hierarchical Zn_(3)V_(2)O_(8)microspheres interconnected via conductive carbon nanotubes as promising anode materials for lithium-ion battery applications

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稀有金属:英文版 2023年第8期42卷 2601-2611页

作者： ming-ming liu Hai-Tao Yu Lang Yuan Ting-Feng Yi Fei He Ying Xie Key Laboratory of Functional Inorganic Material Chemistry Ministry of EducationSchool of Chemistry and Materials ScienceHeilongjiang UniversityHarbin 150080China School of Materials Science and Engineering Northeastern UniversityShenyang 110819China Key Laboratory of Superlight Materials and Surface Technology Ministry of EducationCollege of Materials Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150001China

Zn_(3)V_(2)O_(8) was considered as a promising anode material for lithium-ion battery(LIB),because of its high theoretical specific capacity,environmental friendliness,and ease of ***,the large volume change and low electronic conductivity of Zn_(3)V_(2)O_(8)in repeated charge/discharge cycles have severely limited its *** solve the above issues,hierarchical Zn_(3)V_(2)O_(8) microspheres assembled by two-dimensional(2D)nanosheets were successfully synthesized,and carbon nanotubes(CNTs)were further introduced to cross-link the Zn_(3)V_(2)O_(8) *** interconnected nature of the three-dimensional(3D)conducting network and the special hierarchical morphology were beneficial for improving the stability and conductivity of the composite,leading to the reduction of the impedance and a significant improvement of the electrochemical *** reversible capacity of the as-prepared composite can achieve 1049.5mAh·g^(-1)at a current density of 0.2 A·g^(-1)with a capacity retention of~81%after 100 *** is suggested that morphology modulation coupled with interconnecting CNT network is an effective method to boost the electrochemical performance of the anode materials for lithium-ion batteries.

关键词： Anode material Zn_(3)V_(2)O_(8) Carbon nanotube(CNT) Electrochemical performance Lithium-ion battery(LIB)

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Efficient synthesis of 4(3H)-quinazolinones using a soluble polymeric support

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Chinese Chemical Letters 2008年第5期19卷 505-508页

作者： Chang Xie Hong Xia Li ming Guo liu ming Wu Ding Key Laboratory of Pesticide ＆ Chemical Biology of Ministry of Education Central China Normal University Wuhan 430079 China

4（3H）-Quinazolinones have been synthesized from poly（ethylene glycol）（PEG） supported aza-Wittig reaction. 2-Dialkylamino- 4（3H）-quinazolinones 6 were synthesized efficiently by reaction of secondary amine with PEG-supported carbodiimides 4, which were obtained from aza-Wittig reaction of PEG-supported iminophosphoranes 3 with isocyanates.

关键词： 4(3H)-Quinazolinone Poly(ethylene glycol) supported Aza-Wittig reaction Carbodiimide Iminophosphorane

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Prediction of the amount of urban waste solids by applying a gray theoretical model

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Journal of Environmental Sciences 2003年第1期15卷 43-46页

作者： LI Xiao ming, ZENG Guang ming, WANG ming, liu Jin jin (Department of Environmental Science and Technology, Hunan University, Changsha 410082, China. Department of Environmental Science and Technology Hunan University Changsha 410082 China

Urban waste solids are now becoming one of the most crucial environmental problems. There are several different kinds of technologies normally used for waste solids disposal, among which landfill is more favorable in China than others, especially for urban waste solids. Most of the design works up to now are based on a roughly estimation of the amount of urban waste solids without any theoretical support, which lead to a series problems. To meet the basic information requirements for the design work, the amount of the urban waste solids was predicted in this research by applying the gray theoretical model GM (1,1) through non linear differential equation simulation. The model parameters were estimated with the least square method (LSM) by running a certain MATALAB program, and the hypothesis test results show that the residual between the prediction value and the actual value approximately comply with the normal distribution N (0,0 21 2), and the probability of the residual within the range (-0 17, 0 19) is more than 95%, which indicate obviously that the model can be well used for the prediction of the amount of waste solids and those had been already testified by the latest two years data about the urban waste solids from Loudi City of China. With this model, the predicted amount of the waste solids produced in Loudi City in the next 30 years is 8049000 ton in total.

关键词： gray theoretical model prediction waste solids

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Human melanopsin-AAV2/8 transfection to retina transiently restores visual function in rd1 mice

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International Journal of Ophthalmology(English edition) 2016年第5期9卷 655-661页

作者： ming-ming liu Jia-Man Dai Wen-Yi liu Cong-Jian Zhao Bin Lin Zheng-Qin Yin Southwest Hospital Southwest Eye Hospital Third Military Medical University Chongqing 400038 China Key Lab of Visual Damage and Regeneration and Restoration of Chongqing Chongqing 400038 China Departments of Anatomy and Ophthalmology Li Ka Shing Faculty of Medicine the University of Hong Kong Hong Kong 200131 China

AIM： To explore whether ectopic expression of human melanopsin can effectively and safely restore visual function in rd1 mice.· METHODS： Hematoxylin-eosin staining of retinal sections from rd1 mice was used to detect the thickness of the outer nuclear layer to determine the timing of surgery. We constructed a human melanopsinAAV2/8 viral vector and injected it into the subretinal space of rd1 mice. The Phoenix Micron IV system was used to exclude the aborted injections, and immunohistochemistry was used to validate the ectopic expression of human melanopsin. Furthermore, visual electrophysiology and behavioral tests were used to detect visual function 30 and 45 d after the injection. The structure of the retina was compared between the human melanopsin-injected group and phosphate buffer saline（PBS）-injected group.·RESULTS： Retinas of rd1 mice lost almost all of their photoreceptors on postnatal day 28（P28）. We therefore injected the human melanopsin-adeno-associated virus（AAV） 2/8 viral vector into P30 rd1 mice. After excluding aborted injections, we used immunohistochemistry of the whole mount retina to confirm the ectopic expression of human melanopsin by co-expression of human melanopsin and YFP that was carried by a viral vector. At30 d post-injection, visual electrophysiology and the behavioral test significantly improved. However,restoration of vision disappeared 45 d after human melanopsin injection. Notably, human melanopsin-injected mice did not show any structural differences in their retinas compared with PBS-injected mice.·CONCLUSION： Ectopic expression of human melanopsin effectively and safely restores visual function in rd1

关键词： human melanopsin retinal degenerative diseases visual restoration

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Simulation and optimization of scrap wagon dismantling system based on Plant Simulation

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Visual Computing for Industry,Biomedicine,and Art 2023年第1期6卷 88-96页

作者： Hai-Qing Chen Yu-De Dong Fei Hu ming-ming liu Shi-Bao Zhang School of Mechanical Engineering Hefei University of TechnologyHefei 230009China China Railway Materials Group Resources Technology Co. Ltd.Hefei 230088China

Based on the existing plant layout and process flow,a simulation analysis was conducted using the Plant Simulation platform with the utilization efficiency of each station and production capacity of the dismantling system as indicators.A problem with long-term suspension in the disassembly process was *** on the two optimization directions of increasing material transportation equipment and expanding the buffer capacity,a cost-oriented optimization model is established.A genetic algorithm and model simulation were used to solve the *** optimization scheme that satisfies the production needs and has the lowest cost is *** results show that the optimized dismantling system solves the suspended work problem at the dismantling station and a significant improvement in productivity and station utilization efficiency compared with the previous system.

关键词： Plant Simulation Production optimization Wagon dismantling Genetic algorithm

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Perineuronal nets increase inhibitory GABAergic currents during the critical period in rats

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International Journal of Ophthalmology(English edition) 2013年第2期6卷 120-125页

作者： Hui liu Peng-Fen Gao Hai-Wei Xu ming-ming liu Tao Yu Jun-Ping Yao Zheng-Qin Yin Southwest Eye Hospital Southwest Hospital Third Military Medical University Key Lab of Visual Damage and Regeneration & Restoration of Chongqing

AIM: To investigate inhibitory γ-aminobutyric acid (GABA) ergic postsynaptic currents (IPSCs) and postsynaptic currents (PSCs) in layer IV of the rat visual cortex during the critical period and when plasticity was extended through dissolution of the perineuronal nets (PNNs). METHODS: We employed 24 normal Long-Evans rats to study GABA A-PSC characteristics of neurons within layer IV of the visual cortex during development. The animals were divided into six groups of four rats according to ages at recording: PW3 (P21 -23d), PW4 (P28 -30d), PW5 (P35-37d), PW6 (P42-44d), PW7 (P49-51d), and PW8 (56-58d). An additional 24 chondroitin sulfate proteoglycan (CSPG) degradation rats (also Long-Evans) were generated by making a pattern of injections of chondroitinase ABC (chABC) into the visual cortex 1 week prior to recording at PW3, PW4, PW5, PW6, PW7, and PW8. Immunohistochemistry was used to identify the effect of chABC injection on CSPGs. PSCs were detected with whole-cell patch recordings, and GABA A receptor-mediated IPSCs were pharmacologically isolated. RESULTS: IPSC peak current showed a strong rise in the age-matched control group, peaked at PW5 and were maintained at a roughly constant value thereafter. Although there was a small increase in peak current for the chABC group with age, the peak currents continued to decrease with the delayed highest value at PW6, resulting in significantly different week-by-week com-parison with normal development. IPSC decay time continued to increase until PW7 in the control group, while those in the chABC group were maintained at astable level after an initial increase at PW4. Compared with normal rats, the decay times recorded in the chABC rats were always shorter, which differed significantly at each age. We did not observe any differences in IPSC properties between the age-matched control and penicillinase (P-ase) group. However, the change in IPSCs after chABC treatment was not reflected in the total PSCs or in basic membrane

关键词： gamma-aminobutyric acid receptor plasticity visual cortex development postsynaptic currents chondroitinase ABC chondroitin sulfate proteoglycans whole-cell patch recording

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Emerging materials and transistors for integrated circuits

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National Science Review 2024年第3期11卷 7-8页

作者： ming liu Lian-Mao Peng Lab of Nanofabrication and Novel Device Integration Institute of Microelectronics Chinese Academy of Sciences Key Laboratory for the Physics and Chemistry of Nanodevices and Center for Carbon-based Electronics School of Electronics Peking University

The device technology for integrated circuits(ICs) has received a great deal of attention in the past decade since the mainstream silicon-based complementary metal-oxide-semiconductor(CMOS) field-effect transistor(FET) for modern ICs had been encountering development bottlenecks due to the combination of power constraints, physics, cost and fabrication processes.

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