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A low-latency pipeline for GRB light curve and spectrum using Fermi/GBM near real-time data

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Research in Astronomy and Astrophysics 2018年第5期18卷 99-110页

作者： Yi Zhao Bin-Bin Zhang Shao-Lin Xiong Xi Long Qiang Zhang Li-ming Song jian-Chao Sun Yuan-Hao Wang Han-Cheng Li Qing-Cui Bu Min-Zi Feng Zheng-Heng Li Xing Wen Bo-Bing Wu Lai-Yu Zhang Yong-Jie Zhang Shuang-Nan Zhang jian-Xiong Shao School of Nuclear Science and Technology Lanzhou University Lanzhou 730000 China Key Laboratory of Particle Astrophysics Institute of High Energy Physics Chinese Academy of Sciences Beijing100049 China School of Astronomy and Space Science Nanjing University Nanjing 210093 China Instituto de Astroffsica de Andaluc/a (IAA-CSIC) P.O. Box 03004 E-18080 Granada Spain University of Chinese Academy of Sciences Beijing 100049 China

Rapid response and short time latency are very important for Time Domain Astronomy, such as the observations of Gamma-ray Bursts（GRBs） and electromagnetic（EM） counterparts of gravitational waves（GWs）. Based on near real-time Fermi/GBM data, we developed a low-latency pipeline to automatically calculate the temporal and spectral properties of GRBs. With this pipeline, some important parameters can be obtained, such as T_（90） and fluence, within ～ 20 min after the GRB *** ～ 90% of GRBs, T90 and fluence are consistent with the GBM catalog results within 2σ *** pipeline has been used by the Gamma-ray Bursts Polarimeter（POLAR） and the Insight Hard Xray Modulation Telescope（Insight-HXMT） to follow up the bursts of interest. For GRB 170817 A, the first EM counterpart of GW events detected by Fermi/GBM and INTEGRAL/SPI-ACS, the pipeline gave T90 and spectral information 21 min after the GBM trigger, providing important information for POLAR and Insight-HXMT observations.

关键词： gamma-ray bursts general - polarization - radiation mechanisms non-thermal

Relationship between symptoms and weight-bearing radiographic parameters of idiopathic flexible flatfoot in children

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Chinese Medical Journal 2013年第11期126卷 2029-2033页

作者： YAN Gui-sen YANG Zheng LU ming ZHANG jian-li ZHU Zheng-hua GUO Yuan Department of Pediatric Orthopaedics Beijing Jishuitan Hospitalthe Fourth Clinical Medical College of Peking University Beijing100035 China

Background Idiopathic flexible flatfoot in children most frequently improves with age and remains asymptomatic. It is a physiological variation of the normality that does not require treatment unless it becomes symptomatic. The aim of this research was to investigate the reason why some individuals with flexible flatfoot become symptomatic by analysis of the differences in the relative alignment of each segment of the foot between symptomatic and asymptomatic patients with idiopathic flexible flatfoot using radiographic measurements. Methods One hundred patients with idiopathic flexible flatfoot were retrospectively identified and divided into two groups： asymptomatic （n=50） and symptomatic （n=50）. Standing anteroposterior and lateral radiographs of the foot were analyzed. Five measurements were calculated to describe the alignment of the foot. An independent-samples t-test and Logistic regression test were used for statistical analysis. Results Age and sex were similar in the two groups. The independent-samples test revealed significant differences in two parameters： the anteroposterior talonavicular coverage angle and the lateral talo-first metatarsal angle. When the Logistic regression test was performed, only the talonavicular coverage angle showed statistical significance. Conclusions The lateral displacement of the navicular bone, measured by the anteroposterior talonavicular coverage angle, seems to be related to the onset of symptoms. In individuals with otherwise normal flexible flatfoot, an increase in this angle might be an important risk factor for developing symptoms.

关键词： flexible flatfoot radiographic analysis symptomatic flatfoot children

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半监督聚类的若干新进展

模式识别与人工智能 2009年第5期22卷 735-742页

作者：李昆仑曹铮曹丽苹张超刘明河北大学电子信息工程学院保定071002 保定职业技术学院机电工程系保定071051

半监督聚类方法利用少量标记数据提高聚类算法的性能,已逐渐发展成为模式识别及相关领域的研究热点.文中首先综述了半监督聚类算法的一些新进展,包括基于约束的方法、基于距离的方法和基于距离与约束的融合方法.然后提出一种基于约束的... 详细信息

半监督聚类方法利用少量标记数据提高聚类算法的性能,已逐渐发展成为模式识别及相关领域的研究热点.文中首先综述了半监督聚类算法的一些新进展,包括基于约束的方法、基于距离的方法和基于距离与约束的融合方法.然后提出一种基于约束的半监督模糊C-means聚类算法.实验表明,该算法与传统的模糊C-means及半监督K-means方法相比,具有更好的聚类精度.

关键词：半监督聚类模糊C一均值(FCM) 标记数据无标记数据

Strategies of laparoscopic spleen-preserving splenic hilar lymph node dissection for advanced proximal gastric cancer

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World Journal of Gastrointestinal Surgery 2016年第6期8卷 402-406页

作者： Qi-Yue Chen Chang-ming Huang Chao-Hui Zheng Ping Li jian-Wei Xie Jia-Bin Wang jian-Xian Lin Jun Lu Long-Long cao Mi Lin Ru-Hong Tu Zhi-Liang Hong Department of Gastric Surgery Fujian Medical University Union Hospital

For advanced proximal gastric cancer(GC),splenic hilar(No.10) lymph nodes(LN) are crucial links in lymphatic *** to the 14^(th) edition of the Japanese GC treatment guidelines,a D2 lymphadenectomy is the standard surgery for advanced GC,and No.10 LN should be dissected for advanced proximal *** recent years,the preservation of organ function and the use of minimally invasive technology are being accepted by an increasing number of *** spleenpreserving splenic hilar LN dissection has become more accepted and is gradually being used in ***,because of the complexity of splenic hilar anatomy,mastering the strategies for laparoscopic spleen-preserving splenic hilar LN dissection is critical for successfully completing the operation.

关键词： Gastric neoplasm Laparoscopic Splenic hilus Lymphadenectomy Strategy

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焦炉煤气自重整炉气成分与温度变化规律研究

钢铁 2009年第4期44卷 11-15页

作者：曹朝真郭培民赵沛庞建明钢铁研究总院先进钢铁流程及材料国家重点实验室北京100081

通过CH4-H2-CO-H2O-CO2-O2煤气体系的热力学模拟计算,对焦炉煤气自重整技术进行了研究。结果表明：高温、高CH4含量以及低压有利于焦炉煤气自重整。在配氧量14%,反应温度850-900℃,体系压力为0.3MPa的条件下,对焦炉煤气进行自重整,则还... 详细信息

通过CH4-H2-CO-H2O-CO2-O2煤气体系的热力学模拟计算,对焦炉煤气自重整技术进行了研究。结果表明：高温、高CH4含量以及低压有利于焦炉煤气自重整。在配氧量14%,反应温度850-900℃,体系压力为0.3MPa的条件下,对焦炉煤气进行自重整,则还原气平衡态组分中的氢气的体积分数可由60.0%提高到71.5%,CO体积分数可由8.0%提高到23.1%;气体的还原势为97.2%,还原气体总量约增加33%。

关键词：焦炉煤气自重整直接还原铁

含水Mg_3Al-LDH-Cl的电子结构与成键特征

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化学学报 2011年第24期69卷 2947-2954页

作者：曹根庭胥倩倪哲明浙江海洋学院海洋科学与技术学院舟山316004 杭州师范大学有机硅化学及材料技术教育部重点实验室杭州310012 浙江工业大学化学工程与材料科学学院杭州310014

建立了Mg3Al-LDH-Cl-nH2O(n=0～2)双层周期性计算模型.选用密度泛函理论-赝势平面波法CASTEP,从原子轨道布居、Mulliken电荷布居、态密度(DOS)等方面,计算研究了含层间水情况下体系的电子结构及成键特征,并探求了层间水分子含量及水分... 详细信息

建立了Mg3Al-LDH-Cl-nH2O(n=0～2)双层周期性计算模型.选用密度泛函理论-赝势平面波法CASTEP,从原子轨道布居、Mulliken电荷布居、态密度(DOS)等方面,计算研究了含层间水情况下体系的电子结构及成键特征,并探求了层间水分子含量及水分子的电子屏蔽效应对Mg3Al-LDH-Cl-nH2O材料电子结构的影响.结果表明体系层板上M—O同时具有共价键与离子键两种特征,主客体之间以静电作用为主,而层间客体之间的相互作用以氢键作用为主.层间H2O的电子屏蔽作用主要表现为对层间阴离子的影响以及对层板上二价金属阳离子的影响.主体层板的电价成分和层间域的共价成分均随着水分子数目的增加而增加.

关键词：层状双金属氢氧化物电子结构成键特征密度泛函理论

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混合值逻辑控制系统的状态空间方法

控制与决策 2017年第2期32卷 311-316页

作者：刘新芸赵明明朱建栋南京师范大学数学科学学院南京210023

对于混合值逻辑控制系统,提出确定一个正则子空间的补空间的充分必要条件.对于正则子空间已有的判别准则,给出新的证明,并提出构造补空间的新方法.对于子空间,设计计算其友好子空间的新算法,引入没有正则性假设的不变子空间的概念,获得... 详细信息

对于混合值逻辑控制系统,提出确定一个正则子空间的补空间的充分必要条件.对于正则子空间已有的判别准则,给出新的证明,并提出构造补空间的新方法.对于子空间,设计计算其友好子空间的新算法,引入没有正则性假设的不变子空间的概念,获得判别不变子空间的一系列充分必要条件.

关键词：混合值逻辑控制系统正则子空间友好子空间不变子空间

Unraveling the efficacy network: A network meta-analysis of adjuvant external beam radiation therapy methods after hepatectomy

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 205-214页

作者： Gao-Yuan Yang Zhi-Wei He Yong-Chang Tang Feng Yuan ming-Bo cao Yu-Peng Ren Yu-Xuan Li Xiao-Rui Su Zhi-Cheng Yao Mei-Hai Deng Department of Hepatobiliary Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630Guangdong ProvinceChina Department of General Surgery Qilu HospitalShandong UniversityJinan 250012Shandong ProvinceChina Department of General Surgery The First Affiliated HospitalGuangzhou Medical UniversityGuangzhou 511436Guangdong ProvinceChina Department of Hepatobiliary and Pancreatic Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630Guangdong ProvinceChina

BACKGROUND Primary liver cancer is a malignant tumor with a high recurrence rate that significantly affects patient *** adjuvant external radiation therapy(RT)has been shown to effectively prevent recurrence after liver cancer ***,there are multiple RT techniques available,and the differ-ential effects of these techniques in preventing postoperative liver cancer re-currence require further *** To assess the advantages and disadvantages of various adjuvant external RT methods after liver resection based on overall survival(OS)and disease-free survival(DFS)and to determine the optimal *** This study involved network meta-analyses and followed the PRISMA *** data of qualified studies published before July 10,2023,were collected from PubMed,Embase,the Web of Science,and the Cochrane *** included relevant studies on postoperative external beam RT after liver resection that had OS and DFS as the primary *** magnitudes of the effects were determined using risk ratios with 95%confidential *** results were analyzed using R software and STATA *** A total of 12 studies,including 1265 patients with hepatocellular carcinoma(HCC)after liver resection,were included in this *** was no significant heterogeneity in the direct paired comparisons,and there were no significant differences in the inclusion or exclusion criteria,intervention measures,or outcome indicators,meeting the assumptions of heterogeneity and *** analysis revealed that patients who underwent stereotactic body radiotherapy(SBRT)after resection had longer OS than those who underwent intensity modulated radiotherapy(IMRT)or 3-dimensional conformal RT(3D-CRT).DFS analysis revealed that patients who underwent 3D-CRT after resection had the longest *** who underwent IMRT after resection had longer OS than those who underwent 3D-CRT and longer DFS than those who underwent ***

关键词： Primary liver cancer Hepatocellular carcinoma Network meta-analysis External beam radiation therapy Stereotactic body radiotherapy Intensity modulated radiotherapy

Puerarin modulation of CENPA affects downstream PLK1 and CCNB1 expression to inhibit bladder cancer cell proliferation

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Traditional Medicine Research 2024年第9期9卷 32-41页

作者： Hao Xu Wen Gao Deng Pan Yu-Yang Ma Ruo-Ran Zhang Yong-Li cao Yu-Chuan Zhou ming-Yu Xu Pei-Yong Zhang Kun Pang Department of Urology Xuzhou Central HospitalXuzhou Clinical School of Xuzhou Medical CollegeXuzhou 221009China Graduate School Bengbu Medical UniversityBengbu 233040China Department of Cardiology The Fourth People’s Hospital of JinanJinan 250031China Graduate School Jiangsu UniversityZhenjiang 212013China Department of Urology The Peixian People’s HospitalXuzhou 221699China Department of Clinical Laboratory The First Affiliated Hospital of Harbin Medical UniversityHarbin 150006China

Background:The treatment alternatives for bladder cancer(BLCA),the 10th most prevalent cancer in the world,need to be further investigated,and many active substances like Puerarin in herbal medicine were found to be effective in treating *** purpose of this study was to investigate the potential treating mechanisms of Puerarin on ***:The cell counting kit 8 assay and flow cytometry were performed to confirm Puerarin’s ability to suppress *** differentially expressed proteins(DEPs)were obtained by Tandem Mass Tags technology and functional enrichment analysis performed by R *** most enriched pathways were selected for study and the DEPs were screened ***-protein interaction network maps were created using String and Cytoscape and key proteins,which will be analyzed for survival,expression,and upstream transcription factor prediction,were screened out using the cytoHubba ***3 was used to obtain upstream transcription factor validated by molecular docking and western blotting ***:Cell counting kit 8 showed that Puerarin inhibited BLCA cells,with 50%inhibitory concentration of 218μmol/L in T24 and 198μmol/L in *** cytometry reveals that Puerarin blocks T24 and 5637 cells in G1 phase.1,385 DEPs were obtained and the enrichment analysis revealed that cell cycle and DNA replication were the two main areas in which DEPs were ***-B-cyclin dependent kinase 1(CDK1),cyclin B1(CCNB1),and polo-like kinase 1(PLK1)were identified as key proteins,and their upstream transcription factor was predicted to be centromere protein A(CENPA).Puerarin’s binding energy to CENPA was determined by molecular docking to be−6.3 kcal/mol,indicating a strong binding *** blot showed that Puerarin significantly reduced the expression of ***:We hypothesize that Puerarin may inhibit the proliferation of bladder cancer cells by inhibiting CENPA expression to regulate PLK1 and CCNB1 expression,thereby a

关键词： Puerarin BLCA Tandem Mass Tags cell cycle