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Tungsten 2022年第2期4卷 121-129页

作者： Meng Zhao Xi-Yu Zhu Yan-Zhen Li Jiang-nan Chang ming-Xue Li Li-hua Ma Xiao-Yuan Guo Henan Key Laboratory of Polyoxometalate Chemistry Institute of Molecular and Crystal EngineeringSchool of Chemistry and Chemical EngineeringHenan UniversityKaifeng475004China Agricultural Products’Quality and Safety Testing Center of Kaifeng Kaifeng Agriculture and Rural BureauHenan475004China

In this paper,a new organic–inorganic hybrid compound[Co(L)_(2)]2[W_(6)O_(19)](1)(HL=2-acetylpyridine thiosemicarbazone)was prepared and *** compound 1 exhibits remarkable antibacterial activity by determination of minimum inhibitory concentration(MIC)against Staphylococcus aureus(***,0.06μg·mL^(−1))and Escherichia coli(***,0.24μg·mL^(−1)),***,the potential mechanism of compound 1 was studied in *** potential causes of bacteria death were cell wall/membrane disruption,inhibition of intracellular respiratory chain dehydrogenases(RCD)activity,destruction of reactive oxygen species(ROS)and depletion of glutathione(GSH).

关键词： Isopolytungstate Thiosemicarbazone Bioactivity Mechanism of action

Thermoelectric thin films:Promising strategies and related mechanism on boosting energy conversion performance

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Journal of Materiomics 2020年第3期6卷 494-512页

作者： Xuxuan Chen Zhifang Zhou Yuan-hua Lin Cewen nan State Key of Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing100084PR China

Thermoelectrics can be capable of direct and reversible conversion between heat and *** dimensional thermoelectric materials,especially two dimensional(2D)thin films,have been considered as a breakthrough to decouple the correlations between electronic and thermal transport,contributing to the optimization of thermoelectric *** the past few decades,some effective strategies combined with physical concepts like quantum confinement effect,energy filtering effect,band structure tuning and interface engineering are introduced to design high performance *** a thorough understanding the underlyingmechanisms is essential to develop thermoelectric ***,our review summarizes the major strategies that can be utilized in thermoelectric thin films,including fabrication of superlattice structure,formation of two-dimensional electron gas(2DEG)system,orientation regulation,strain engineering and magnetic manipulation,from the aspects of deep mechanisms analyses,recent progress and prospects,inspiring significant improvement of thermoelectric properties.

关键词： Thermoelectrics Thin film Strategy Mechanism

Activation of autophagy in the retina after optic nerve crush injury in rats

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International Journal of Ophthalmology(English edition) 2019年第9期12卷 1395-1401页

作者： Li-hua Kang Su Zhang Sheng Jiang nan Hu Eye Institute Affiliated Hospital of Nantong UniversityNantong 226001Jiangsu ProvinceChina nanjing Medical University Affiliated Eye Hospital Nanjing 210000Jiangsu ProvinceChina

AIM: To investigate the activation of autophagy in rat retina after optic nerve crush(ONC) and evaluate its relationship with apoptosis of retinal ganglion cells(RGCs).METHODS: The ONC model was established. Western blots were performed to investigate expression of p62, LC3 and Beclin-1. Transmission electron microscopy was performed to discover the autophagosomes in the retina after ONC. Immunohistochemistry was used to confirm the distribution of LC3. TUNEL was performed to confirm the relationship between autophagy and RGC apoptosis. RESULTS: p62/Beclin-1 ratio was declined shortly after ONC until to day 7 after ONC and then restored to a normal level at day 21. There was an opposite change in the LC3-II/LC3 I ratio in the retina compared to the p62/Beclin-1 ratio. Increased autophagosomes were found after ONC using transmission electron microscopy, and most of the LC3-stained cells were colocalized with RGCs and Müller cells. More LC3-immunoreactive cells and apoptotic RGCs were found on day 7 following ONC. CONCLUSION: Possible activation of autophagy in RGCs after ONC;autophagy mainly occurred in RGCs and Müller cells, and the apoptosis of RGCs after ONC may be partly associated with autophagic activation.

关键词： autophagy optic nerve crush apoptosis retinal ganglion cells rat

Sternal Hodgkin’s lymphoma: A case report and review of literature

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World Journal of Clinical Cases 2020年第3期8卷 638-644页

作者： Yi-Yu Yin nan Zhao Bin Yang hua Xin Department of Thoracic Surgery China-Japan Union Hospital of Jilin University

BACKGROUND Sternal tumors are difficult to diagnose, and usually need to be differentiated from other diseases such as tuberculosis, osteosarcoma, intrathoracic thyroid and thymoma. The sternum is a rare site of Hodgkin’s lymphoma, which is often misdiagnosed as tuberculosis on routine *** SUMMARY We reported a 47-year-old female patient with chest pain in the upper sternum for 1 mo. Chest computed tomography found a mass in the upper *** and immunohistochemistry of the biopsy confirmed the diagnosis of typical Hodgkin’s lymphoma(mixed cellularity subtype). Patient was diagnosed with primary sternal Hodgkin’s lymphoma and administered 6 cycles of adriamycin, bleomycin, vinblastine, and dacarbazine chemotherapy. Patient had no tumor recurrence and progression at a follow-up visit 2 years *** This study highlights the rarity of primary sternal Hodgkin’s lymphoma and the challenges of its diagnosis. A Pub Med and Web of Science search revealed 10 reported cases of sternal involvement in Hodgkin’s lymphoma.

关键词： Sternum Skeleton Hodgkin’s Lymphoma Chest pain Case report

Inspired by novel radiopharmaceuticals:Rush hour of nuclear medicine

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Chinese Journal of Cancer Research 2023年第5期35卷 470-482页

作者： Yang Liu Ya-nan Ren Yan Cui Song Liu Zhi Yang hua Zhu nan Li Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals(National Medical Products Administration)Department of Nuclear MedicinePeking University Cancer Hospital&InstituteBeijing 100142China State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers Beijing Key Laboratory of Carcinogenesis and Translational ResearchNMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals(National Medical Products Administration)Department of Nuclear MedicinePeking University Cancer Hospital&InstituteBeijing 100142China

Nuclear medicine plays an irreplaceable role in the diagnosis and treatment of *** are important components of nuclear *** the radiopharmaceuticals approved by the Food and Drug Administration(FDA),radio-tracers targeting prostate-specific membrane antigen(PSMA)and somatostatin receptor(SSTR)have held essential positions in the diagnosis and treatment of prostate cancers and neuroendocrine neoplasms,*** recent years,FDA-approved serials of immune-therapy and targeted therapy drugs targeting programmed death 1(PD-1)/programmed death ligand 1(PD-L1),human epidermal growth factor receptor 2(HER2),and nectin cell adhesion molecule 4(Nectin 4).How to screen patients suitable for these treatments and monitor the therapy?Nuclear medicine with specific radiopharmaceuticals can visualize the expression level of those targets in systemic lesions and evaluate the efficacy of *** addition to radiopharmaceuticals,imaging equipment is also a key step for nuclear *** equipment including total-body positron emission tomography/computed tomography(PET/CT)and positron emission tomography/magnetic resonance imaging(PET/MRI)has been developed,which contribute to the diagnosis and treatment of tumors,as well as the development of new ***,we conclude most recently advances of radiopharmaceuticals in nuclear medicine,and they substantially increase the“arsenal”of clinicians for tumor therapy.

关键词： Nuclear medicine radiopharmaceuticals neoplasms

Inhibition of trehalase affects the trehalose and chitin metabolism pathways in Diaphorina citri(Hemiptera:Psyllidae)

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Insect Science 2021年第3期28卷 718-734页

作者： Hai-Zhong Yu Yu-Ling huang Zhan-Jun Lu Qin Zhang hua-nan Su Yi-ming Du Long Yi Ba-Lian Zhong Ci-Xiang Chen College of Life Sciences Gannan Normal UniversityGanzhouJiangxiChina National Navel Orange Engineering Research Center GanzhouJiangxiChina China-USA Citrus huanglongbing Joint Laboratory A Joint Laboratory of The University of Florida and Gannan Normal UniversityGanzhouJiangxiChina Fruit Bureau of Ganzhou GanzhouJiangxiChina

The Asian citrus psyllid,Diaphorina citri is the principal vector of huanglongbing,which transmits Candidatus Liberibacter *** is a key enzyme involved in trehalose hydrolysis and plays an important role in insect growth and *** specific functions of this enzyme in *** have not been *** this study,three trehalase genes(DcTreJ-1,DcTrel-2,and DcTre2)were identified based on the *** genome *** analysis showed that DcTrel-1 and DcTrel-2 are related to soluble trehalase,whereas DcTre2 is associated with membrane-bound *** expression analysis indicated that DcTrel-1 and DcTrel-2 had the highest expression levels in the head and wing,respectively,and DcTre2 had high expression levels in the fat ***,DcTrel-1 and DcTrel-2 expression levels were induced by 20-hydroxyecdysone and juvenile hormone III,but DcTre2 was *** expression levels of DcTrel-1,DcTrel-2,and DcTre2 were significantly up-regulated,which resulted in high mortality after treatment with *** activities and glucose contents were downregulated,but the trehalose content increased after treatment with *** addition,the expression levels of chitin metabolism-related genes significantly decreased at 24 and 48 h after treatment with ***,silencing of DcTrel-1,DcTrel-2,and DcTre2 reduced the expression levels of chitin metabolism-related genes and led to a malformed phenotype of *** results indicate that *** trehalase plays an essential role in regulating chitin metabolism and provides a new target for control of ***.

关键词： chitin metabolism Diaphorina citric RNA interference trehalase validamycin

Real-Time Characterization of Fibrinogen Interaction with Modified Titanium Dioxide Film by Quartz Crystal Microbalance with Dissipation

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Chinese Journal of Chemical Physics 2014年第3期27卷 355-360页

作者： An-sha Zhao Zhao Wang Xiao-hua Zhu Manfred F. Maitz nan huang Key Laboratory of Advanced Materials Technology of Ministry of:Education Department of Materials Science and Engineering Southwest Jiaotong University Chengdu 510031 China Leibniz Institute of Polymer Research Dresden Max Bergmann Center of Biomaterials Dresden Dresden Germany

The adsorption of fibrinogen can be used as a quick indicator of surface haemocompatibility because of its prominent role in coagulation and platelet adhesion. In this work the molecular interaction between fibrinogen and a modified titanium oxide surface/platelet has been studied by quartz crystal microbalanee with dissipation （QCM-D） in situ. In order to further characterize the conformation of adsorbed fibrinogen, αC and γ-chain antibody were used to check the orientation and denaturation of fibrinogen on solid surface. QCM-D investiga- tions revealed the fibrinogen have the trend to adsorb on hydropllilic surface in a side-on orientation by positively charged αC domains, which would reduce the exposure of platelet bonding site on γ chain and enable less platelet adhesion and be activated. These obser- vations suggest that certain conformations of adsorbed fibrinogen are less platelet adhesive than others, which opens a possibility for creating a non-platelet adhesive substrates.

关键词： Quartz crystal microbalance with dissipation Fibrinogen adsorption Confor- mation change Blood platelet

A novel Fe(OH)3/TiO2 nanoparticles and its high photocatalytic activity

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Chinese Chemical Letters 2007年第10期18卷 1261-1264页

作者： nan Wang Li hua Zhu Jing Li He Qing Tang Department of Chemistry and Chemical Engineering Hubei Key Lab of Bioinorganic Chemistry and Materia Medica Huazhong University of Science and Technology Wuhan 430074 China

A very simple and controllable approach was proposed to synthesize novel Fe（OH）3/TiO2 nanoparticles. Compared with neat TiO2, the Fe（OH）3/TiO2 increased the rate of the photocatalytic degradation of methyl orange at pH 6.0 by more than five times, showing photocatalytic activity as excellent as P25. This enhancing effect is mainly attributed to the ferric hydroxide deposits as the electron scavenger and the enriched surface hydroxyl groups.

关键词： Titanium dioxide Surface modification Ferric hydroxide Photocatalysis

Changes of feeding patterns in Chinese city children under 2 years from 1985 to 2015: results from a series of national cross-sectional surveys

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World Journal of Pediatrics 2019年第2期15卷 176-181页

作者： hua-Hong Wu Ya-Qin Zhang Xin-nan Zong Hui Li Department of Growth and Development Capital Institute of PediatricsYaBao RoadChaoYang DistrictBeijing 100020China

Background In China,as the social transformation and economic development from 1985 to 2015,children's feeding pattern has undergone some *** we aimed to analyze the secular trend on feeding patterns of city children in *** All data were from a series of national survey which implemented once every 10 years in China from 1985 to *** use same indexes to evaluate the feeding pattern of children in these four *** From 1985 to 2005,the exclusive breastfeeding rates in infants under 6 months of age decreased,especially in suburban areas decreased by 17.7%;the continuous breastfeeding rate of 1-year-old children in suburban area decreased from 60.1 to 27.6%.However,from 2005 to 2015,the exclusive breastfeeding rates under 6 months of age increased by 16.0% in urban areas and 5.9% in suburban areas;the continuous breastfeeding rate of 1-year-old children in urban increased from 17.0 to 36.0%.The overall feeding rate of complementary food in infants under 6 months of age declined from 1985 to 2015;the average age at introduction of all complementary foods was around 6 months of age in *** There is an obvious trend on feeding pattern of Chinese *** 1985 to 2005,the breastfeeding rate decreased,the duration time of breastfeeding was shortened and the age at introduction of complementary food was *** 2005 to 2015,the breastfeeding rate increased,the duration time of breastfeeding was prolonged,and the age at introduction of complementary food was postponed.

关键词： Breastfeeding Complementary feeding Infant and young children Secular change

Method for determining the best frequency band for eavesdropping the display image of a PC

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The Journal of China Universities of Posts and Telecommunications 2013年第4期20卷 93-98页

作者： DU Yu-lei Lü Ying-hua ZHANG Jin-ling ZHANG nan School of Telecommunication Engineering Beijing University of Posts and Telecommunications

The display image of the video display unit （VDU） can be reconstructed by receiving and analyzing the unexpected electromagnetic noise emanated from a personal computer system. This fact is one of the information leakage threats in information security. Therefore, in order to choose the best frequency range for receiving the electromagnetic compromising emanations form a PC display effectively and quickly, a method based on the correlation power analysis （CPA） and the common equipments is proposed. Firstly, the frequency spectrum of 10 MHz to 1 GHz is measured about 10 times respectively when the PC is displaying the white-black vertical strips image and black image. The frequency range which contains the display information can be obtained through the CPA. And then, the special image signal is searched around the dot frequency and harmonics. If the special signal disappears when displaying the total black image, it can be judged to be the real special signal. Finally, the best receiving frequency range can be chosen by comprehensive considering the results of CPA and the signal to noise ratio （SNR） of the special image signal. In order to check the validity of the chosen frequency range, eavesdropping experiments are carried out. The results demonstrate that the selected frequency range can retrieve the higher quality image than other frequency bands.

关键词： electromagnetic secure compromising emanations CPA eavesdropping TEMPEST