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Frontiers of Medicine 2013年第2期7卷 270-273页

作者： Fei Liu ming-chon hsiung Haibo Song Ke Dian Hong Tang Jin Liu Department of Anesthesiology West China HospitalSichuan UniversityChengdu 610041China Department of Cardiology Cheng Hsin General HospitalTaibeiTaiwanChina

In the presence of a large patent ductus arteriosus(PDA),aortic co-arctation(CoA)cannot be diagnosed clinically because PDA masks the clinical *** condition impedes the identification of CoA by transthoracic ***,the closure of PDA can result in a severe clinical condition that causes a patient with undiagnosed CoA to suffer from shock and multi-organ *** this article,a case of PDA was presented,in which transesophageal echocardiography provided full information that could be used as reference to identify and define CoA during PDA ligation surgery.

关键词： patent ductus arteriosus aortic co-arctation transesophageal echocardiography

Percutaneous transcatheter closure of mitral paravalvular leak via transarterial retrograde approach

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Journal of Geriatric Cardiology 2015年第6期12卷 683-686页

作者： Ho-Ping Yu Chi-Hung Huang Shaw-Min Hou ming-chon hsiung Shen-Kou Tsai Wei-Hsian Yin Heart Center Cheng-Hsin General Hospital Taipei Taiwan China Division of Cardiology Cathay General Hospital Taipei Taiwan China Division of Cardiac Surgery Cathay General Hospital Taipei Taiwan China Department of Anesthesiology Cheng-Hsin General Hospital Taipei Taiwan China Faculty of Medicine School of Medicine National Yang Ming University Taipei Taiwan China

Repeat surgery has usually been considered the first choice to solve paravalvular leaks of prosthetic valves, but it cames a high operative risk, a high mortality rate and an increased risk for re-leaks. Percutaneous closure of such defects is possible, and different approaches and devices are used for this purpose. For mitral paravalvular leaks, constructing an arterio-venous wire loop for delivering the closure device through an antegrade approach is the most commonly used technique. Transcatheter closure can also be performed through a transapical approach or retrograde transfemoral arterial approach. We present a case of 68-year-old man with a mitral paravalvular leak that was suc- cessfully closed using an Amplatzer~ Duct Occluder H, via retrograde transfemoral arterial approach under three-dimensional transesophag- eal echocardiographic guidance, without the use of a wire loop. The initial attempt to cross the paravalvular defect was unsuccessful, but the obstacle was finally overcome by introducing complex interventional techniques.

关键词： Antegrade approach Paravalvular leaks Prosthetic valve Retrograde approach Wire loop

Feasibility and short-term outcomes of transcatheter valve-in-valve implantation for failed aortic and mitral bioprosthesis-a single-center experience

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Journal of Geriatric Cardiology 2018年第7期15卷 486-495页

作者： Wei-Hsian YIN Yung-Tsai LEE Tien-Ping TSAO Kuo-Chen LEE Ho-Ping YU ming-chon hsiung Jeng WEI Heart Center Cheng Hsin General Hospital Taipei Taiwan China Faculty of Medicine Cheng Hsin General Hospital Taipei Taiwan China Institute of Microbiology and Immunology.School of Medicine National Yang Ming University Taipei Taiwan China Faculty of Medicine National Defense Medical Center Taipei Taiwan China

Objectives Transcatheter valve-in-valve （VIV） implantation for failed bioprostheses has become an alternative to open surgery in those deemed high risk. The purpose of this study was to evaluate the effectiveness and outcomes of this emerging procedure. Methods Fourty VIV procedures were performed in 38 consecutive patients （mean age 70 ± 14 years and mean Logistic EuroScore 23.6 ± 15.5%） with severe aortic （n = 19） or mitral （n = 21） bioprosthetic valve dysfunction between 2014 and 2017. Bioprosthetic failure was secondary to stenosis in 11 （27.5%）, regurgitation in 19 （47.5%）, and combined in 10 （25.0%） bioprostheses. Clinical, echocardiographic, and procedural profiles were characterized, and the short-term results of the study patients were reported. Results Successful transfemoral （n = 15）, trans-subclavian （n = 1）, or transapical （n = 3） aortic VIV using either balloon-expandable valves （Edwards Sapien XT, n = 7） or self-expandable valves （Medtronic CoreValve, n = 12）; and transapical （n = 21） mitral VIV using either Edwards Sapien XT （n = 15） or me-chanically expandable valves （Boston Scientific Lotus, n = 6） were accomplished in all 40 VIV procedures. Implantation was successful with immediate restoration of satisfactory valve function in all patients. Five patients （13.2%） died at a median follow up of 9.3 months. Most of the 33 patients alive were in good functional status with good prosthetic valve performance. Conclusions Transcatheter VIV implantation is a feasible and safe option for the management of bioprosthetic valve failure. It may offer a less invasive alternative for those high-risk patients needing repeat valve replacement.

关键词： Aortic valve Bioprosthesis Mitral valve Transcatheter Valve-in-valve

实时三维经胸超声心动图测量缩流面积评价主动脉瓣反流

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临床超声医学杂志 2008年第3期10卷 148-150页

作者：方理刚 Navin C.NANDA ming chon hsiung 程康安朱文玲中国医学科学院中国协和医科大学北京协和医院心内科北京市100730 Division of Cardiovascular Disease University of Alabama

目的应用实时三维经胸超声心动图（3D-TTE）测量缩流面积（VCA）评价主动脉瓣反流。方法将56例主动脉瓣反流患者的三维测量的VCA以及二维经胸超声心动图（2D-TTE）测量的缩流宽度与主动脉根部造影和外科手术的主动脉瓣反流程度相比较。... 详细信息

目的应用实时三维经胸超声心动图（3D-TTE）测量缩流面积（VCA）评价主动脉瓣反流。方法将56例主动脉瓣反流患者的三维测量的VCA以及二维经胸超声心动图（2D-TTE）测量的缩流宽度与主动脉根部造影和外科手术的主动脉瓣反流程度相比较。结果3D—TTE测得的VCA与主动脉根部造影和外科手术的主动脉瓣反流程度密切相关（r=0．95），无明显重叠。2D—TTE测得的缩流宽度亦与主动脉根部造影和手术的主动脉瓣反流程度有很好的相关性（r=0．92），但有较多的重叠。以主动脉根部造影和外科手术为主动脉瓣反流程度的标准，三维测得的1～4度主动脉瓣反流的相应VCA分别为≤0．19cm^2，0．2～0．39cm^2，0．4～0．59cm^2，≥0．6cm^2。结论实时3D—TTE彩色多普勒能准确评价主动脉瓣反流，且和主动脉根部造影有很好的相关性。

关键词：超声心动描记术三维实时主动脉瓣反流缩流面积缩流宽度

实时三维经胸超声心动图测量缩流面积评价主动脉瓣反流

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实时三维经胸超声心动图测量缩流面积评价主动脉瓣反流

Decoding complexity: the need to enhance precision and streamline spatial understanding in neuroscience

中华医学会心血管病学分会第八次全国心血管病学术会议

作者：方理刚 Navin C．Nanda ming chon hsiung Andrew P．Miller 程康安朱文玲中国医学科学院中国协和医科大学北京协和医院心内科美国阿拉巴马大学医院心内科心脏超声实验室

目的本研究应用实时三维经胸超声心动图测量缩流面积评价主动脉瓣反流。方法研究纳入56例患者,女性36例,男性20例,年龄在16～81岁,平均年龄(58±17)岁。所有患者在行经胸三维超声心动图 (3D TTE)72 h内行主动脉根部造影。主动脉瓣反流...

目的本研究应用实时三维经胸超声心动图测量缩流面积评价主动脉瓣反流。方法研究纳入56例患者,女性36例,男性20例,年龄在16～81岁,平均年龄(58±17)岁。所有患者在行经胸三维超声心动图 (3D TTE)72 h内行主动脉根部造影。主动脉瓣反流的病因为心内膜炎8例,瓣膜脱垂6例,二叶瓣畸形7 例,风心病4例,退行性改变20例,主动脉扩张或主动脉瘤8例,原因不明3例,多数患者左室射血分数正常,包括50例>55％,1例为45％～55％,5例33％～45％,主动脉瓣反流中央型37例,偏心型19例。所有患者为窦性心律。所有患者接受了标准二维经胸超声心动图(2D TTE)和实时三维经胸超声心动图检查。

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Neural Regeneration Research 2025年第3期20卷 801-802页

作者： Sameehan Mahajani Armita Salahi Brenda Gonzalez Charlotte Nelson Frank hsiung Biology&Applications Division NodexusSan JoseCAUSA

Neuroscience is the ultimate frontier in our quest for a comprehensive understanding of human behavior. Since its launch in 2009, the Human Connectome Project has emerged as a pioneering force, making heroic strides i... 详细信息

关键词： behavior frontier dating

Prevalence of advanced colonic polyps in asymptomatic Chinese

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World Journal of Gastroenterology 2005年第30期11卷 4731-4734页

作者： Hui-hsiung Liu Meng-Chen Wu Yeh Peng ming-Shiang Wu Graduate Institute of Public Health Taipei Medical University Taipei Taiwan China Taipei Institute of Pathology Taipei Taiwan China Division of Gastroenterology Department of Internal Medicine National Taiwan University Hospital Departmentof Primary Care medicine School of Medicine National Taiwan University Taipei Taiwan China

AIM: To investigate the prevalence of advanced polyps in asymptomatic Chinese and to determine the risk of proximal advanced colonic polyps in subjects with and without polyps in the distal ***: Data were collected prospectively during colonoscopic examinations performed in 5 973 subjects as part of health evaluation at our unit from December 1997 to December 2003. Polyps were considered advanced, if they were larger than 10 mm or were tubovillous, villous or malignant. Proximal colon was defined as the splenic flexure and more proximal portions of the ***: Colon polyps were detected in 971 (16.3%)subjects (613 males and 358 females) with their mean age being 56.6±10.7 years. Advanced polyps were noted in 199 (3.3%) individuals. Subjects were sub-classified according to the location of polyps into three groups: distal (569, 58.6%), proximal (284, 29.2%), and combined proximal and distal (118, 12.2%) groups. Subjects with advanced polyps in these three groups were 95 (9.8%),56 (5.8%), and 48 (4.9%) respectively. In the 48 subjects with advanced combined polyps, 13 advanced polyps were distributed at the distal colon, 17 at the proximal colon,and 18 at both. Eighteen colon cancers including 12 at sigmoid and 6 at ascending colon were confirmed by final pathology. The relative risk for advanced proximal polyp according to distal findings was 3.1 (95%CI: 1.3-7.4) for hyperplastic polyp, 2.7 (95%CI: 1.4-5.3) for tubular polyp and 13.5 (95%CI: 5.1-35.4) for advanced polyp as compared to that for no polyp. However, 56 (28.2%) of 199 subjects with advanced polyps had no index polyps at the distal colon and might go undetected under sigmoidoscopic ***: Although distal lesions can predict the risk of advanced proximal polyps, a substantial portion of Chinese with advanced proximal polyps is not associated with any distal sentinel lesions. These data have implications for screening policy of colon cancers in Taiwan Residents Chinese.

关键词： Colon Polyp Colonoscopy Screening Epidemiology

Biloma following repeated transcatheter arterial embolization and complicated by intrahepatic duct stones: A case report

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World Journal of Gastroenterology 2005年第30期11卷 4764-4765页

作者： ming-Jen Chen Ching-Chung Lin Wen-hsiung Chang Fei-Shih Yang Division of Gastroenterology Department of Radiation

Biloma is an encapsulated bile collection outside the biliary tree due to a bile leak. It is occasionally found following traumatic liver injury or iatrogenic injury to the biliary tract, induced either during an endoscopic or surgical procedure. It is a rare complication of transcatheter arterial embolization (TAE). Although biloma can be shrunk by appropriate aspiration or drainage in majority of cases,we report a case of intrahepatic biloma following repeated TAE for hepatocellular carcinoma (HCC) and complicated by infection and intrahepatic stones. This particular constellation of problems has not been reported before and the intrahepatic stones need to be removed by percutaneous procedure.

关键词： Biloma Biliary tract Transcatheter Arterial embolization

Endoscopic findings in a patient with Henoch-Schonlein purpura

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World Journal of Gastroenterology 2005年第15期11卷 2354-2356页

作者： ming-Jen Chen Tsang-En Wang Wen-hsiung Chang Shu-Jung Tsai Division of Gastroenterology

Henoch-Schonlein purpura (HSP) is a systemic vasculitis of the small vessels of the skin, joints, GI tract, and kidney. It preferentially affects children but may also occur in adults. We report a 60-year-old man with HSP who presented with colicky abdominal pain, bloody diarrhea, arthralgia, and skin rash. The gastrointestinal tract was viewed by upper endoscopy and colonoscopy. We found characteristic endoscopic findings in the stomach, cecum and sigmoid colon, the combination of which has rarely been demonstrated in one patient. Histologic examination of skin biopsy specimens revealed leukocytoclastic vasculitis with positive staining for IgA in the capillaries. Endoscopy appears to have substantial diagnostic utility in patients suspected of having HSP, especially when abdominal symptoms precede the cutaneous lesions.

关键词： Henoch-Schonlein purpura Purpura Endoscopy

Prediction of protein content in rice using a near-infrared imaging system as diagnostic technique

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International Journal of Agricultural and Biological Engineering 2019年第2期12卷 195-200页

作者： Lian-hsiung Lin Fu-ming Lu Yung-Chiung Chang Department of Biomechatronic Engineering National Ilan UniversityIlan 260Taiwan Department of Bio-Industrial Mechatronics Engineering National Taiwan UniversityTaipei 106Taiwan Department of Horticulture National Ilan UniversityIlan 260Taiwan

The aim of this research was to determine the rice protein content utilizing a NIR imaging *** developed imaging system utilized a NIR camera which installed automatically exchanged filters with the wavelength range from 870 nm to 1014 *** liner regression(MLR),partial least square regression(PLSR),and artificial neural network(ANN)models were employed as data analysis methods for 6.18%-9.43%rice protein detections within both the NIR imaging system and commercial NIRS.A total of 180 rice samples were used in this study,of which 120 random samples were selected as a calibration set for the MLR and PLSR ***,for establishing the back-propagation ANN model,the same 120 samples were divided into two parts,80 samples were used for network training and the other 40 were established as the monitoring *** compare with the results of MLR,PLSR,and ANN models,the remaining 60 of the total 180 samples were established as the validation *** an MLR linear regression model composed of five wavelengths;the NIR imaging system successfully detected rice protein *** predicting results of r_(val)^(2) and SEP were 0.769 and 0.294%,*** PLSR model,utilizing the imaging system obtained the results of r_(val)^(2)=0.782,and SEP=0.274%within the wavelength range from 870 nm to 1014 *** significant wavelengths selected by the MLR model were the same as the input data of the ANN model,and the prediction results were r_(val)^(2)=0.806,and SEP=0.266%.The prediction results indicated that the developed NIR imaging system has the advantages of simple,convenient operation,and high detection accuracy as well as it presents commercial potential in non-destructive detection of rice protein content.

关键词： non-destructive detection near-infrared imaging system inner quality rice protein content agriculture product