检索结果-南通市图书馆

The terpene synthase(TPS)gene family in kiwifruit shows high functional redundancy and a subset of TPS likely fulfil overlapping functions in fruit flavour,floral bouquet and defence

引用

Molecular Horticulture 2023年第1期3卷 258-279页

作者： Wu wang mindy y.wang yunliu Zeng Xiuyin Chen Xiaoyao wang Anne M.Barrington Jianmin Tao Ross G.Atkinson Niels J.Nieuwenhuizen The New Zealand Institute for Plant and Food Research Ltd(PFR) Private Bag 92169AucklandNew Zealand Institute of Botany Jiangsu Province and Chinese Academy of SciencesNanjing 210014China Key Laboratory of Horticultural Plant Biology College of Horticulture and Forestry ScienceHuazhong Agricultural UniversityWuhan 430070People’s Republic of China College of Horticulture Nanjing Agricultural UniversityNanjing 210095China

Volatile terpenes are important compounds that influence fruit flavour and aroma of *** in plants also impact on the floral bouquet and defence against pests and pathogens in leaves and *** better understand the overlapping roles that terpenes may fulfil in plants,a systematic gene,chemical and biochemical analysis of terpenes and terpene synthases(TPS)was undertaken in Red5 kiwifruit(Actinidia spp.).Analysis of the Red5 genome shows it contains only 22 TPS gene models,of which fifteen encode full-length *** TPS can account for the major terpene volatiles produced in different tissues of Red5 kiwifruit and in response to different *** small Red5 TPS family displays surprisingly high functional redundancy with five TPS producing linalool/*** of leaves and fruit with methyl jasmonate enhanced expression of a subset of defence-related TPS genes and stimulated the release of *** TPS genes were induced upon herbivory of leaves by the economically important insect pest Ctenopseustis obliquana(brown-headed leaf roller)and emission,but not accumulation,of(E)-and(Z)-nerolidol was strongly linked to *** results provide a framework to understand the overlapping biological and ecological roles of terpenes in Actinidia and other horticultural crops.

关键词： Actinidia Aroma Genome analysis Monoterpene Sesquiterpene Volatile

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current update on molecular cytogenetics, diagnosis and management of gastrointestinal stromal tumors

引用

World Journal of Gastroenterology 2021年第41期27卷 7125-7133页

作者： mindy X wang Catherine Devine Nicole Segaran Dhakshinamoorthy Ganeshan Department of Diagnostic Imaging University of Texas MD Anderson Cancer CenterHoustonTX 77030United States Department of Radiology Mayo Clinic ArizonaPhoenixAZ 85259United States

Gastrointestinal stromal tumors(GISTs)are the most common mesenchymal tumors of the gastrointestinal(GI)tract and are thought to arise from precursors of the interstitial cells of *** can arise anywhere in the GI tract,but most commonly originate from the stomach and small *** majority of GISTs occur as a result of activating mutations in two receptor protein tyrosine kinases:KIT and/or platelet-derived growth factor receptor-α.Mutational analyses allow for predicting patient prognosis and treatment *** presentations can vary from no symptoms,typical in the case of small incidentally found tumors,to GI bleeding,abdominal discomfort,and ulcer-related symptoms when the tumor is *** plays a critical role in the diagnosis and management of these tumors with multiphasic computed tomography serving as the imaging modality of *** resonance imaging and positron emission tomography-computed tomography can serve as imaging adjuncts in lesion characterization,especially with liver metastases,and subsequent staging and assessment for treatment response or *** resection is the preferred management for small GISTs,while tyrosine kinase inhibitors−imatinib mesylate and sunitinib malate−serve as crucial molecular-targeted therapies for locally advanced and metastatic *** review article highlights the clinical presentation,pathology and molecular cytogenetics,imaging features,and current management of GISTs.

关键词： Gastrointestinal stromal tumors Cytogenetics Diagnostic imaging Computed tomography Magnetic resonance imaging Imatinib mesylate

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comparing the intraoperative complication rate of femtosecond laser-assisted cataract surgery to traditional phacoemulsification

引用

International Journal of Ophthalmology(English edition) 2015年第1期8卷 201-203页

作者： Ming Chen Christian Swinney mindy Chen University of Hawaii School of Medicine A.T. Still School of Medicine

AIM: To compare the complication rate of femtosecond laser-assisted cataract surgery(FLACS) and traditional phacoemulsification for the first 18 mo of FLACS use at a private surgical center in ***: A retrospective chart review was conducted from January 2012 to June 2013. The first 273 consecutive eyes receiving FLACS and 553 eyes receiving traditional phacoemulsification were *** surgeries were performed at a single surgical center in Hawaii. The presence of intraoperative complications was used as the main outcome measure. Approval was obtained from the institutional review board of the University of ***: The overall complication rate for FLACS was 1.8%, while that of the traditional procedure was5.8%(P y of the surgeons(80%) had a lower complication rate while using ***: FLACS is comparable in safety, if not safer, than traditional cataract surgery when performed by qualified cataract surgeons on carefully selected patients.

关键词： femtosecond laser cataract surgery cataract surgery complications phacoemulsification

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Retrospective analysis of hepatitis C infected patients treated through an integrated care model

引用

World Journal of Gastroenterology 2016年第38期22卷 8558-8567页

作者： James M Levin Shabnam Dabirshahsahebi mindy Bauer Eric Huckins Department of Infectious Disease Dean Clinic

AIM To determine if our health system's integrated model reflects sustained virologic response(SVR) outcomes similar to those in clinical trial data, maximizes adherence, and averts drug *** Subjects with chronic hepatitis C had their medical records reviewed from November 1st, 2014 through March 1st, 2016. Patients eligible for treatment were entered into an integrated care model therapy algorithm. The primary outcome was SVR12 based on intention to treat(ITT) analysis. Inclusion criteria consisted of both treatment na?ve and experienced patients over the age of 18 who were at least twelve weeks post-therapy completion with any genotype(GT) or METAVIR score. Secondary outcomes included adherence, adverse events, and number of drug interaction *** At the time of analysis, 133 patients had reached twelve weeks post therapy with ITT. In the ITT analysis 70 patients were GT 1a, 26 GT 1b, 23 could not be differentiated between GT 1a or 1b, 8 GT 2, 4 GT 3, and 2 patients with multiple genotypes. The ITT treatment regimens consisted of 97 sofosbuvir(SOF)/ledipasvir(LDV), 8 SOF/LDV and ribavirin(RBV), 7 SOFand Simeprevir(SMV), 6 3D and RBV, 1 3D, 11 SOF and RBV, and 1 SOF, peg interferon alpha, and RBV. The overall SVR12 rate was 93% in the ITT analysis with a total of 6 patients relapsing. In patients with cirrhosis, 89% obtained SVR12. All 33 patients who were previous treatment failures achieved SVR12. Drug-drug interactions were identified in 56.4% of our patient population, 69 of which required interventions made by the pharmacist. The most common side effects were fatigue(41.4%), headache(28.6%), nausea(18.1%), and diarrhea(8.3%). No serious adverse effects were *** Dean Health System's integrated care model successfully managed patients being treated for hepatitis C virus(HCV). The integrated care model demonstrates high SVR rates amongst patients with different levels of fibrosis, genotypes, and HCV treatment histo

关键词： Hepatitis C Medication adherance Direct acting antiviral Sustained viral response Integrated care model

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Time of infliximab therapy initiation and dose escalation in Crohn's disease

引用

World Journal of Gastroenterology 2014年第1期20卷 214-218页

作者： mindy CW Lam Terry Lee Kenneth Atkinson Brian Bressler Division of Gastroenterology Department of MedicineUniversity of British ColumbiaVancouverBC V6Z 2K5Canada Centre for Health Evaluation and Outcome Sciences VancouverBC V6Z 2K5Canada

AIM: To determine if early initiation of anti-tumor necrosis factor therapy affects the need for dose escalation.

关键词： Crohn’ s disease, Infliximab, Dose escalation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current update on imaging for pancreatic neuroendocrine neoplasms

引用

World Journal of Clinical Oncology 2021年第10期12卷 897-911页

作者： Nicole Segaran Catherine Devine Mindy.wang Dhakshinamoorthy Ganeshan Department of Radiology Mayo Clinic ArizonaPhoenixAZ 85259United States Department of Diagnostic Radiology The University of Texas MD Anderson Cancer CenterHoustonTX 77030United States Department of Diagnostic Radiology Abdominal ImagingThe University of Texas MD Anderson Cancer CenterHoustonTX 77030United States

Pancreatic neuroendocrine neoplasms(panNEN)are a heterogeneous group of tumors with differing pathological,genetic,and clinical *** on clinical findings,they may be categorized into functioning and nonfunctioning *** of the 2017 World Health Organization classification system,particularly its differentiation between grade 3,well-differentiated pancreatic neuroendocrine tumors(panNET)and grade 3,poorly-differentiated pancreatic neuroendocrine carcinomas(panNEC)has emphasized the role imaging plays in characterizing these *** ultrasound can help obtain biopsy specimen and assess tumor margins and local *** patterns on computed tomography(CT)and magnetic resonance imaging(MRI)may be used to classify *** enhanced MRI and diffusion-weighted imaging have been reported to be useful for characterization of panNEN and quantifying metastatic *** and emerging radiotracers have broadened the utility of functional imaging in evaluating ***-18 fluorodeoxyglucose positron emission tomography(PET)/CT and somatostatin receptor imaging such as Gallium-681,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid–octreotate PET/CT may be useful for improved identification of panNEN in comparison to anatomic *** new techniques can also play a direct role in optimizing the selection of treatment for individuals and predicting tumor response based on somatostatin receptor *** addition,emerging methods of radiomics such as texture analysis may be a potential tool for staging and outcome prediction in panNEN,however further investigation is required before clinical implementation.

关键词： Pancreatic neuroendocrine neoplasms Computed tomography Ultrasound Positron emission tomography Magnetic resonance imaging Peptide receptor radionuclide therapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

come on,have fun!

引用

优雅 2014年第8期 124-125页

作者： mindy

来源：评论

学校读者我要写书评

暂无评论

Features of primary pancreatic lymphoma:A bi-institutional review with an emphasis on typical and atypical imaging features

引用

World Journal of Clinical Oncology 2021年第9期12卷 823-832页

作者： Nicole Segaran Kumaresan Sandrasegaran Catherine Devine mindy X wang Chintan Shah Dhakshinamoorthy Ganeshan Department of Radiology Mayo Clinic ArizonaPhoenixAZ 85054United States Department of Diagnostic Imaging University of Texas MD Anderson Cancer CenterHoustonTX 77030United States

BACKGROUND Primary pancreatic lymphoma(PPL)is a rare *** able to distinguish it from other pancreatic malignancies such as pancreatic ductal adenocarcinoma(PDAC)is important for appropriate *** PDAC,PPL is highly sensitive to chemotherapy and usually does not require ***,being able to identify PPL preoperatively will not only direct physicians towards the correct avenue of treatment,it will also avoid unnecessary surgical *** To evaluate the typical and atypical multi-phasic computed tomography(CT)imaging features of *** A retrospective review was conducted of the clinical,radiological,and pathological records of all subjects with pathologically proven PPL who presented to our institutions between January 2000 and December *** review board approval was obtained for this *** collected data were analyzed for subject demographics,clinical presentation,laboratory values,CT imaging features,and the treatment *** of all CT imaging findings including size,site,morphology and imaging characteristics of PPL such as the presence or absence of nodal,vascular and ductal involvement in these subjects were *** those subjects who had a pre-treatment multiphasic CT of the abdomen were included in the *** Twenty-nine cases of PPL were diagnosed between January 2000 and December 2020(mean age 66 years;13 males/16 females).All twenty-nine subjects were symptomatic but only 4 of the 29 subjects(14%)had B *** jaundice occurred in 24%of *** lactate dehydrogenase was seen in 81%of cases,whereas elevated cancer antigen 19-9 levels were present in only 10%of cases for which levels were *** vast majority(90%)of tumors involved the pancreatic head and uncinate *** tumor size was 7.8 cm(range,4.0-13.8 cm).PPL presented homogenous hypoenhancement on CT in 72%of *** volume peripancreatic lymphadenopathy was seen in 28%

关键词： Pancreatic tumors Primary pancreatic lymphoma Pancreatic ductal adenocarcinoma Imaging features Diagnosis Computed tomography

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Microsoft Exchange 2000 Server协作式网络编程

引用

丛书名： Microsoft编程系列

2001年

作者：（美）mindy Martin 彭松虎等译

本书是一本用Exchange 2000和微软Web Storage System建立性能可靠的服务器应用程序的指导手册。全书共分五部分，内容包括ADO和Exchange CDO、CDO消息发送、利用Outlook 2000进行开发等。

ISBN: (纸本)7900631585

关键词：互连网络应用程序数据交换

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Neonatal Isolation Stress Inhibits Pre-Weaning Weight Gain and Mild-Stressor Induced Locomotor Activity in Early Adolescent Male and Female Rats

引用

Journal of Behavioral and Brain Science 2015年第7期5卷 306-317页

作者： Peter Villavecchia mindy J. D. Miserendino Department of Psychology Sacred Hear University Fairfield USA

The present study looked at the effects of neonatal isolation, an early life stress experience, in male and female early adolescent rats, an age which is underrepresented in the early stress literature. Four stress-sensitive indices were assessed: weight gain during the pre-weaning period, open field activity, and locomotor activity in response to two mild stressors: exposure to a novel environment, and a single IP saline injection. Rats in the neonatal isolation condition were removed from dam and littermates on postnatal days 2-9 in accord with the procedure used by Kehoe et al. (1995);behavioral testing occurred on PN25-PN30 during the early adolescent period. It was found that neonatally isolated pups weighed less than non-isolate controls on each of three measurement days (PN7, PN14, PN21) throughout the pre-weaning period. Further, neonatal isolation experience consistently reduced horizontal locomotor activity measured in the open field, in a novel environment, and following a single mild acute stressor. On some measures, behavior reflected greater impact of NI in males compared with NI females, suggesting that the effects of NI in early adolescent rats may be sexually dimorphic.

关键词： Neonatal Isolation Early Life Stress Adolescent Sex Differences Open Field Test

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：