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Outpatient insulin use in type 2 diabetes mellitus and acute respiratory distress syndrome outcomes:A retrospective cohort study

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World Journal of Clinical Cases 2024年第17期12卷 2966-2975页

作者： Georges Khattar Samer Asmar Laurence Aoun Fares Saliba Shaza Almardini Saif Abu Baker Catherine Hong Carolla El Chamieh Fadi Haddadin Toni Habib Omar Mourad Zeina Morcos Fatema Arafa Jonathan mina Khalil El Gharib Mohammad Aldalahmeh Salman Khan Elie Bou Sanayeh Department of Medicine Holy Spirit University of KaslikJounieh 00000Lebanon Department of Internal Medicine Staten Island University HospitalStaten IslandNY 10305United States Public Heath and Biostatistics Independent ResearchBeirut 0000Lebanon Department of Medicine Lebanese UniversityBeirut 00000Lebanon Department of Medicine University of BalamandBeirut 00000Lebanon Department of Medicine Lebanese American UniversityBeirut 00000Lebanon Department of Medicine Northwell Health Staten Island University HospitalNew YorkNY 10305United States

BACKGROUND The impact of type 2 diabetes mellitus(T2DM)on acute respiratory distress syndrome(ARDS)is debatable.T2DM was suspected to reduce the risk and complications of ***,during coronavirus disease 2019(COVID-19),T2DM predisposed patients to ARDS,especially those who were on insulin at *** evaluate the impact of outpatient insulin use in T2DM patients on non-COVID-19 ARDS *** We conducted a retrospective cohort analysis using the Nationwide Inpatient Sample *** patients diagnosed with ARDS were stratified into insulin-dependent diabetes mellitus(DM)(IDDM)and non-insulindependent DM(NIDDM)*** applying exclusion criteria and matching over 20 variables,we compared cohorts for mortality,duration of mechanical ventilation,incidence of acute kidney injury(AKI),length of stay(LOS),hospitalization costs,and other clinical *** Following 1:1 propensity score matching,the analysis included 274 patients in each ***,no statistically significant differences emerged between the IDDM and NIDDM groups in terms of mortality rates(32.8%vs 31.0%,P=0.520),median hospital LOS(10 d,P=0.537),requirement for mechanical ventilation,incidence rates of sepsis,pneumonia or AKI,median total hospitalization costs,or patient disposition upon *** Compared to alternative anti-diabetic medications,outpatient insulin treatment does not appear to exert an independent influence on in-hospital morbidity or mortality in diabetic patients with non-COVID-19 ARDS.

关键词： Acute respiratory distress syndrome Type 2 diabetes mellitus Insulin Length of stay Mortality Endotracheal intubation Acute kidney injury Coronavirus disease 2019

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Salvage locoregional therapies for recurrent hepatocellular carcinoma

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World Journal of Gastroenterology 2023年第3期29卷 413-424页

作者： Cody R Criss mina S Makary Heritage College of Osteopathic Medicine Ohio UniversityAthensOhio 45701United States Department of Radiology The Ohio State University Wexner Medical CenterColumbusOhio 43210United States

Hepatocellular carcinoma(HCC)is the second most common cause of cancerrelated death *** the advent of screening efforts and algorithms to stratify patients into appropriate treatment strategies,recurrence rates remain *** contrast to first-line treatment for HCC,which relies on several factors,including clinical staging,tumor burden,and liver function,there is no consensus or general treatment recommendations for recurrent HCC(R-HCC).Locoregional therapies include a spectrum of minimally invasive liver-directed treatments which can be used as either curative or neoadjuvant therapy for ***,we provide a comprehensive review of recent evidence using salvage loco-regional therapies for R-HCC after failed curative-intent.

关键词： Recurrent hepatocellular carcinoma Locoregional therapy Transarterial chemoembolization Transarterial embolization Transarterial radioembolization Ablation Salvage therapy

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Synthesis of phenanthrimidazole from 9,10-phenanthraquinone and aldehydes by molecular iodine as catalyst

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Chinese Chemical Letters 2009年第1期20卷 5-8页

作者： Hossein Behmadi mina Roshani Seyed Mahdi Saadati Department of Chemistry Faculty of Basic SciencesIslamic Azad UniversityMashhad Branch Department of Chemistry Faculty of Basic SciencesIslamic Azad University

A new,convenient,efficient,and cost-effective one-pot synthesis of 1H-phenanthro[9,10]imidazol-2-yl from phenantherenquinone and aldehydes,using molecular iodine as catalyst is *** present methodology offers several a... 详细信息

关键词： 1H-Phenanthroimidazol-2-yl Phenantherenquinone Molecular iodine

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DESIGN OF A SOFTWARE AGENT FOR BUSINESS GAMING SIMULATION

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Journal of Systems Science and Systems Engineering 2006年第1期15卷 83-94页

作者： Yuji SHINODA mina RYOKE Takao TERANO Yoshiteru NAKAMORI School of Knowledge Science Japan Advanced Institute of Science and Technology 1-1 Asahidai Nomi Ishikawa 923-1292 Japan Graduate School of Business Sciences University of Tsukuba Tokyo 3-29-1 Otsuka Bunkyo Tokyo 112-0012 Japan Dept. Computational Intelligence and Systems Science Tokyo Institute of Technology 4259 Nagatsuda-cho Midori-ku Yokohama 226-8503 Japan

This paper introduces a software agent as a virtual player of the business game called Bakery Game. The business game is a tool to understand business and management principles through experience in a virtual world. In order to construct software agents for the gaming simulation, which is able to participate in a game and become human players' worthy rival, we combine a simple model that considers the property of Bakery Game with a strategy adjustment model. The agent has so-called strategy parameters that are updated through the experience. The agent changes his strategy depending on particular situation. The agent participates in the game that is regenerated from log data in various situations.

关键词： Gaming simulation strategy searching agent based simulation

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Effects of sugarcane residue biochar and P fertilizer on P availability and its fractions in a calcareous clay loam soil

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Biochar 2020年第3期2卷 357-367页

作者： mina Safian Hamidreza Motaghian Alireza Hosseinpur Department of Soil Science College of AgricultureShahrekord UniversityShahrekordIran

Biochar has the potential to affect the cycle of phosphorus(P),but the underlying mechanisms of its effects remain poorly understood in calcareous *** understanding of the effects of biochar is limited in calcareous soils during ***,this study was conducted to investigate how the availability and mineral fractions of P change after the addition of combined biochar and P fertilizer during incubation in calcareous *** residue(raw SR)and biochar(400℃for 2 h)were added to soils treated with 50 mg kg−1 of P,in the form of Ca(H_(2)PO_(4))_(2)·H_(2)O,at 0.5 and 1%(w/w).The soils were incubated at 25±1℃for 120 *** P(Olsen P)contents and mineral P fractions were measured after various incubation times(7,30,90,and 120 days).Biochar addition remarkably increased the amount of available P when compared with the raw SR treatment and the control condition(P<0.05).After 30 days of incubation,the amount of available P in the soils decreased and remained unchanged *** results indicated that the addition of 50 mg kg−1 of P as fertilizer significantly augmented the labile P and P associated with Fe and Al in all the treatments at all incubation times(P<0.05).In comparison with P treated with raw SR,P associated with Fe and Al was significantly enhanced after biochar addition(P<0.05).Significant correlations were found for available P with labile P and P associated with Fe and *** found that biochar addition could increase available pools,thus improving available P concentrations at various incubation ***,we conclude that sugarcane residue biochar can enhance the available P in calcareous soils.

关键词： Organic amendment Incubation time Available pool

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显微根尖手术治疗根尖周炎的效果观察

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浙江医学 2024年第15期46卷 1636-1639页

作者：周月华胡米娜周武绍兴市口腔医院牙体牙髓科 312000 绍兴市口腔医院口腔颌面外科 312000

目的观察显微根尖手术对根尖周炎的治疗效果。方法回顾性选取2019年1月至2023年1月在绍兴市口腔医院诊治的根尖周炎患者75例。其中38例患者行显微根尖手术治疗,为观察组;另37例患者行传统根尖手术治疗,为对照组。比较两组患者术后7 d疼... 详细信息

目的观察显微根尖手术对根尖周炎的治疗效果。方法回顾性选取2019年1月至2023年1月在绍兴市口腔医院诊治的根尖周炎患者75例。其中38例患者行显微根尖手术治疗,为观察组;另37例患者行传统根尖手术治疗,为对照组。比较两组患者术后7 d疼痛发生情况、术后并发症发生情况、术前和术后7 d牙周指标,包括菌斑指数(PLI)、牙龈出血指数(GBI)和牙周袋探诊深度(PD);比较两组患者术后12个月疗效。结果观察组患者术后7 d疼痛发生率低于对照组(7.89%比27.03%,P<0.05),术后并发症发生率小于对照组(7.89%比37.84%,P<0.05)。两组患者术后7 d PLI、GBI和PD均低于术前(均P<0.05),且观察组患者术后7 d PLI、GBI和PD均低于对照组(均P<0.05)。观察组患者术后12个月治疗总有效率高于对照组(97.37%比78.38%,P<0.05)。结论显微根尖手术治疗根尖周炎效果显著,且可显著改善牙周指标,降低术后疼痛和并发症发生风险,值得临床推广应用。

关键词：显微根尖手术根尖周炎疗效牙周指标

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Medicinal properties of Peganum harmala L. in traditional Iranian medicine and modern phytotherapy: a review

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Journal of Traditional Chinese Medicine 2015年第1期35卷 104-109页

作者： mina Cheraghi Niroumand Mohammad Hosein Farzaei Gholamreza Amin Department of Traditional Pharmacy Faculty of Traditional Medicine Tehran University of Medical Sciences Faculty of Pharmacy Kermanshah University of Medical Sciences Department of Pharmacognosy School of Pharmacy and Medicinal Plants Research Center Tehran University of Medical Sciences

OBJECTIVE： To review the pharmacological activities of Peganum harmala L. （R harmala, Nitrariaceae） in traditional Iranian medicine （TIM） and mod- ern phytotherapy. METHODS： Opinions of TIM and modern phytotherapy about safety and acceptable dosage of this plant are discussed. Various medical properties of P. harmala were collected from important TIM references and added to scientific reports derived from modern medical databases like PubMed, Scirus, ScienceDirect and ***： The main medicinal part of the plant is the seed. In TIM resources, this plant possesses vari- ous Pharmacological activities such as carminative, galactagogue, diuretic, emmenagogue, antithrom-botic and analgesic. In modern phytotherapy, R harmala demonstrated numerous medicinal effects including cardiovascular, neurologic, antimicrobial, insecticidal, antineoplasmic, antiproliferative, gastrointestinal and antidiabetic effects. Adverse events such as neuro-sensorial symptoms, visual hallucination, bradycardia, hypotension, agitation, tremors, ataxia, abortion and vomiting cause peo- ple to use this plant cautiously. R harmala is contraindicated during pregnancy, due to its abortive and mutagenic activities. Because of increasing the expression of CYP1A2, 2C19, and 3A4 and inhi- bition of monoamine oxidase, the pharmacokinetic parameters of drugs which are mainly metabolized by these enzymes may be affected by R har- mala. CONCLUSION： The medicinal properties declared for this plant in TIM are compared with those showed in modern phytotherapy. Some of the TIM properties were confirmed in modern phytotherapy like emetic and analgesic activities and some have not been evaluated in modern phytotherapy such as its therapeutic effects on paralysis, epilepsy and numbness. Finally, the current review provides the evidence for other researchers to use TIM properties of P. harmala as an efficacious natural drug. Further preclinical and clinical studies for adequate evaluating safety and therape

关键词： Peganum harmala Pharmacologicalphenomena Medicine, traditional Phytotherapy Review

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基于淀粉微球交联剂的低浓度羟丙基胍胶压裂液性能研究

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石油与天然气化工 2024年第3期53卷 105-112页

作者：陈馥杜鹏张林何坤忆钟诚贺杰罗米娜西南石油大学化学化工学院四川省油气田应用化学重点实验室中国石油西南油气田公司安全环保与技术监督研究院

目的针对低渗透油藏,需要降低压裂液稠化剂用量,减少对储层的伤害,并确保压裂液具备延迟交联、携砂等性能和耐温耐剪切性能。方法利用反相乳液聚合法合成淀粉微球,通过硅配体和硼羟基修饰淀粉微球表面,制备了一种交联性能优良、伤害性... 详细信息

目的针对低渗透油藏,需要降低压裂液稠化剂用量,减少对储层的伤害,并确保压裂液具备延迟交联、携砂等性能和耐温耐剪切性能。方法利用反相乳液聚合法合成淀粉微球,通过硅配体和硼羟基修饰淀粉微球表面,制备了一种交联性能优良、伤害性低的微球型硅硼交联剂(KBSM)。结果KBSM交联剂能够实现多活性位点交联,增强交联密度,从而降低羟丙基胍胶(HPG)的用量,具有延迟交联特性。其延迟交联时间在2~6 min内可调。质量分数为0.2%的HPG交联冻胶在120℃、170 s-1剪切120 min后的黏度为80 mPa·s。交联冻胶中砂质量分数(以下简称携砂比)为40%时,陶粒沉降速度为0.1167 cm/min。加入质量分数为0.25%的过硫酸铵破胶剂可使交联冻胶在90℃下、120 min内完全破胶,且残渣质量浓度为214 mg/L。同时,破胶液的岩心损害率为26.55%。结论基于淀粉微球交联剂的低含量羟丙基胍胶压裂液对于降低低渗储层伤害有一定的指导意义。

关键词：淀粉微球有机硅硼交联剂羟丙基胍胶低伤害性

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Three-component synthesis of imidazo[1,2-c]pyrimidines using silica sulfuric acid(SSA)

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Chinese Chemical Letters 2014年第1期25卷 149-151页

作者： Mohammad Bakherad Ali Keivanloo Masoumeh Siavashi mina Omidian School of Chemistry Shahrood University of Technology

This letter describes a simple and efficient synthesis of 3-（cyclohexylamino）-7-hydroxy-2-arylimi- dazo[1,2-c]pyrimidin-5（6H）-one via a one-pot three-component reaction of cyclohexyl isocyanide, an aldehyde, and 4... 详细信息

关键词： Multi-component reaction (MCR)Silica sulfuric acidlsocyanideImidazo[l 2-c] pyrimidines

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多源融合降水实况分析产品在海河流域的适用性评估

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气候与环境研究 2024年第1期29卷 25-35页

作者：庄园煌陈宏余文韬孙密娜徐姝韩婷婷天津市气象台天津300074 中国气象局水文气象重点开放实验室北京100081

基于逐小时地面站点降水观测数据和国家气象信息中心研发的5 km多源融合降水实况分析产品,采用算术平均法对2021年6~9月海河流域面雨量进行估算。通过相关系数、平均误差和均方根误差等多种评估指标,客观定量评估多源融合降水实况分析... 详细信息

基于逐小时地面站点降水观测数据和国家气象信息中心研发的5 km多源融合降水实况分析产品,采用算术平均法对2021年6~9月海河流域面雨量进行估算。通过相关系数、平均误差和均方根误差等多种评估指标,客观定量评估多源融合降水实况分析产品在海河流域的适用性。结果表明:多源融合降水实况分析产品与地面观测资料估算的面雨量结果基本一致,能较好地反映2021年6~9月海河流域面雨量的时空变化特征,但在量值上存在高估且随着降水量增加,估算误差也越大。分区对比,融合实况分析产品和站点的误差与子流域的平均降水量、海拔高度和面积密切相关。对于各量级面雨量出现的频次,融合实况分析产品与站点整体相差不大,准确率可以达到90%及以上。总体而言,5 km多源融合降水实况分析产品的质量较高,可进一步应用于海河流域精细化面雨量监测业务中。

关键词：海河流域多源融合降水实况分析产品面雨量数据评估

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