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Analysis of properties of krypton ion-implanted Zn-polar ZnO thin films

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Chinese Physics B 2021年第9期30卷 528-533页

作者： Qing-Fen Jiang Jie Lian min-ju ying ming-Yang Wei Chen-Lin Wang Yu Zhang School of Information Science and Engineering Shandong Provincial Key Laboratory of Laser Technology and ApplicationShandong UniversityJinan 250100China Key Laboratory of Beam Technology of ministry of Education College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China

The optical properties of materials are of great significance for their device *** numbers of krypton ions are doped into high-quality Zn-polar ZnO films fabricated by molecular beam epitaxy(MBE)on sapphire substrates through ion *** is chemically *** structures,morphologies,and optical properties of films are *** x-ray diffraction(XRD)spectra confirm the wurtzite structures of Zn-polar ZnO *** force microscopy(AFM)results show that the films have pit surface structure and higher roughness after Kr ion implantation.A detailed investigation of the optical properties is performed by using the absorption spectrum,photoluminescence(PL),and spectroscopic ellipsometry(SE).The absorption spectrum is measured by UV-visible spectrophotometer and the bandgap energy is estimated by the Tauc *** results show that the absorption increases and the bandgap decreases after Kr ion ***,the Kr ion implantation concentration also affects the properties of the *** ellipsometry results show that the films'refractive index decreases with the Kr ion implantation concentration *** results can conduce to the design and optimization of Kr ion-implanted polar ZnO films for optoelectronic applications.

关键词： polar ZnO film molecular beam epitaxy Kr implantation optical properties bandgap

Systematic Acupuncture Explains Acupuncture at Baihui(GV20) and Fengchi(GB20) Targeting the Inflammatory Response to Regulate Migraine

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Journal of Traditional Chinese Medicine 2025年

作者： min Yu ZHENG Meifeng SUN ju PENG Zetong CAO Zhixian HUANG Xiaohua Medical College of Acu-Moxi and Rehabilitation， Guangzhou University of Chinese Medicine Department of Rehabilitation Medicine， the Affiliated Panyu Central Hospital of Guangzhou Medical University

Objective: To take Baihui (GV20) and Fengchi (GB20) targeting inflammatory response to regulate migraine as an example to describe a new method for studying the mechanism of stimulating ***: The target information of Baihui (GV20) and Fengchi (GB20) was retrieved， and after intersection with migraine， Kyoto Encyclopedia of Genes and Genomes (KEGG)， Reactome， and UniProt Keywords were used for functional enrichment. After selecting the main pathway， rats were selected and nitroglycerin was used for modeling， and the behavioral scores， inflammatory factors， heme oxygenase 1 (HMOX1)， protein kinase B (AKT1)， signal transducer and activator of transcription 3 (STAT3)， phosphorylated extracellular signal-regulated kinase 1/2 (P-ERK1/ERK2) and other states of the rats in the acupuncture， twisting， and electroacupuncture groups were ***: A total of 135 Baihui (GV20) targets and 27 Fengchi (GB20) targets were collected. A total of 73 target information were obtained after the intersection of these targets in migraine. These 73 targets have three main pathways: hypoxia-inducible factor 1 (HIF-1) signaling pathway， signaling by interleukins and inflammatory response. The main targets in the pathway were verified and found that interleukin-1 beta (IL-1β)， interleukin-6 (IL-6)， tumor necrosis factor-alpha (TNF-α) and HMOX1， AKT1， STAT3， P-ERK1/ERK2 can be regulated by Baihui (GV20) and Fengchi (GB20).Conclusion: Baihui (GV20) and Fengchi (GB20) can regulate migraine by regulating inflammatory factors and HMOX1， AKT1， STAT3， P-ERK1/ERK2 and other changes in HIF-1 signaling pathway， Signaling by Interleukins and Inflammatory response pathways. Based on systems biology and network pharmacology， and with the model of "acupoint-target-disease"， explore the research methods of systematic acupuncture and moxibustion. We believe this is a usable research direction for exploring the mechanism of acupuncture stimulation.

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De novo synthesis of atropisomeric benzofurans via Cu/SPDO complex catalyzed asymmetric formal [3 + 2] annulation

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Science China Chemistry 2025年第1期 174-180页

作者： Fan-Xiao Meng Xing-Yu Wang Ka Lu ju-Song Yang Fu-min Zhang Ai-jun Ma Bao Du Yong-Qiang Tu State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical Engineering Lanzhou University School of Chemistry and Chemical Engineering Shanghai Jiao Tong University School of Biotechnology and Health Sciences Wuyi University

Herein, the de novo synthesis of atropisomeric benzofurans through the Cu/spirocyclic-pyrrolidine-oxazoline(SPDO) complex catalyze asymmetric formal [3 + 2] cycloaddition between quinones and ynamides is explored, producing a range of structurally diverse axially chiral benzofurans in satisfactory yields with good to excellent enantioselectivities. Furthermore, density functional theory calculations were applied to explain the possible reaction mechanism.

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Bromodimethylsulfonium bromide: A brominating reagent for the conversion of anthracene into 9,10-dibromoanthracene

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Chinese Chemical Letters 2014年第3期25卷 435-437页

作者： Xin Zhang ju-Yan Liu ying Wang min-min Yue Bin Yuan College of Chemistry Tianjin Key Laboratory of Structure and Performance for Functional MoleculeKey Laboratory of Inorganic-Organic Hybrid Functional Material ChemistryMinistry of EducationTianjin Normal University

Bromodimethylsulfonium bromide （BDMS） was used as an efficient brominating reagent for the synthesis of 9,10-dibromoanthracene in dichloromethane. The desired products were obtained in excellent yields.

关键词： Bromodimethylsulfonium bromideBrominating reagent9 10-Dibromoanthracene

Diversity of Nitrogenase Systems in Diazotrophs

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Journal of Integrative Plant Biology 2006年第7期48卷 745-755页

作者： ying Zhao Shao-min Bian Hui-Na Zhou ju-Fu Huang Key Laboratory of Photosynthesis and Environmental Molecular Physiology Institute of Botany the Chinese Academy of Sciences Beijing 100093 China School of Graduate the Chinese Academy of Sciences Beijing 100039 China

Nitrogenase is a metalloprotein complex that catalyses the reaction of biological nitrogen fixation. At least three genetically distinct nitrogenase systems have been confirmed in diazotrophs, namely Nil, Vnf, and Anf, in which the active-site central metals are Mo, V, and Fe, respectively. The present review summarizes progress on the genetic, structural, and functional investigations into the three nitrogenases and discusses the possibility of the existence of other novel nitrogenases.

关键词： diazotroph FeMo-cofactor and cofactors substituted for Mo nitrogenase system P-cluster.

A one-dimensional transport model for multi-component solute in saturated soil

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Water Science and Engineering 2018年第3期11卷 236-242页

作者： Zhi-hong Zhang Jia-pei Zhang Zhan-ying ju min Zhu Key Laboratory of Urban Security and Disaster Engineering of ministry of Education Beijing University of Technology

A modified multi-component solute diffusion equation described with diffusion flux was derived in detail based on the classical MaxwellStefan diffusion theory. The friction between the solute species and the soil skeleton wall, which is proportional to the relative velocity between the solute species and the soil skeleton, is introduced. The chemical potential gradient is considered the driving force. A one-dimensional model for transport of multi-component solute in saturated soil was developed based on the modified diffusion equation and the modified competitive Langmuir adsorption equation. Numerical calculation of a case of two heavy metal ion species, which was chosen as an example, was carried out using the finite element software COMSOL Multiphysics. A comparative analysis was performed between the multi-component solute transport model developed in this study and the convection-diffusion transport model of single-component solute based on Fick's law. Simulation results show that the transport behavior of each species in a multi-component solute system is different from that in a single-component system, and the friction characteristics considered in the developed model contribute to obstructing the movement of each solute component. At the same time,the influence of modified competitive Langmuir adsorption on solute transport was investigated. These research results can provide strong theoretical support for the design of antifouling barriers in landfills and the maintenance of operation stability.

关键词： Multi-component solute Maxwell-Stefan diffusion Competitive adsorption Friction Transport

Effects of hepatitis E virus infection on interferon production via ISG15

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World Journal of Gastroenterology 2018年第20期24卷 2173-2180页

作者： min Wang ying Huang Man He Wen-ju Peng De-ying Tian Tongji Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030Hubei ProvinceChina The First Affiliated Hospital of Sun Yat-sen University Guangzhou 510700Guangdong ProvinceChina

AIM To assess the effects of hepatitis E virus(HEV) on the production of type Ⅰ interferons(IFNs) and determine the underlying *** We measured the production of interferon(IFN)-alpha and-beta(-α/β) in genotype 3 HEV-infected C3 A cells at different time points(0, 8, 12, 24, 48, 72 and 120 h) by enzyme-linked immunosorbent assay(ELISA). The expression levels of IFN-stimulated gene(ISG)15 in HEVinfected C3A cells at different time points were tested by western blotting. The plasmid-expressing open reading frame 3(ORF3) or control plasmids(green fluorescent protein-expressing) were transfected into C3A cells, and the levels of IFN-α/β and ISG15 were evaluated, respectively. Furthermore, the plasmid-expressing ISG15 or small interfering RNA-inhibiting ISG15 was transfected into infected C3A cells. Then, the production of IFN-α/β was also measured by *** We showed that genotype 3 HEV could enhance the production of IFN-α/β and induce elevation of ISG15 in C3A cells. HEV ORF3 protein could enhance the production of IFN-α/β and the expression of ISG15. Additionally, ISG15 silencing enhanced the production of IFN-α/β. Overexpression of ISG15 resulted in the reduction of IFN-α/β.CONCLUSION HEV may promote production of IFN-α/β and expression of ISG15 via ORF3 in the early stages, and increased ISG15 subsequently inhibited the production of IFN-α/β.

关键词： open reading frame 3 interferon-stimulated gene 15 interferon-alpha Hepatitis E virus interferonbeta

Microstructure and mechanical properties of directly thixoforged complex box-shape 2A14 part with large wall-thickness difference

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Transactions of Nonferrous Metals Society of China 2024年第12期34卷 3876-3892页

作者： ying-ze LIU ju-fu JIANG ying ZHANG min-jie HUANG Jian DONG ying WANG National Key Laboratory for Precision Hot Processing of Metals School of Materials Science and EngineeringHarbin Institute of TechnologyHarbin 150001China School of Mechatronics Engineering Harbin Institute of TechnologyHarbin 150001China

To form complex box-shape parts with large wall-thickness difference,a directly thixoforged technology of 2A14 alloy with low-cost and short-process was proposed and *** results showed that complex components were successfully *** grains in the microstructure of the thixoforged parts exhibited a large deformation *** led to an obvious improvement in the mechanical properties of the thixoforged *** obvious liquid segregation was found in the *** mechanical properties were obtained in the thixoforged 2A14 alloy *** yield strength varied from 157.1 to 187.3 MPa,the ultimate tensile strength varied from 268.2 to 316.6 MPa,and the elongation varied from 7.8%to 24.9%.Increase in plastic deformation degree caused by larger size and less round grains is beneficial to the mechanical properties of the thixoforged components.

关键词： thixoforging microstructure mechanical properties 2A14 aluminum alloy

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弹性网络正则化的高维序列因果关联识别研究

华北理工大学学报（自然科学版） 2025年第1期47卷 96-105页

作者：张居营安风楼河北金融学院金融与投资学院河北保定071051 太平洋证券股份有限公司北京100033

弹性网络正则化方法兼顾了L1正则化与L2正则化的优点,能够解决高维时间序列因果关系分析中共线性、过度拟合与信息冗余等问题,有效发掘高维序列之间的主要关联关系。首先,基于VAR模型与长期格兰杰因果关联网络,阐述高维序列因果关联识... 详细信息

弹性网络正则化方法兼顾了L1正则化与L2正则化的优点,能够解决高维时间序列因果关系分析中共线性、过度拟合与信息冗余等问题,有效发掘高维序列之间的主要关联关系。首先,基于VAR模型与长期格兰杰因果关联网络,阐述高维序列因果关联识别的方法;其次,讨论了弹性网络正则化如何解决高维序列因果关系建模的弊端,融合L1与L2正则化的主要特点;最后,结合多维大宗商品期货价格日度波动率序列,探索了弹性网络正则化在高维序列因果关联识别的应用,并与其他正则化方法进行比较。结果表明,弹性网络正则化方法避免了信息冗余与“过度稀疏化”的问题,识别与提炼商品价格波动因果关联网络中的主要影响节点与传导关系,挖掘序列关系网络中的主要因果关联。

关键词：弹性网络正则化高维序列长期格兰杰因果关联网络