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Research on dynamic response characteristics of CFRP/Al HC SPs subjected to high-velocity impact

Defence Technology（防务技术） 2018年第5期14卷 503-512页

作者： Guo-wen Gao En-ling Tang min-hui feng Ya-fei Han Yue Li Mei Liu Ying-liang Xu Li Wang Xiao-chu Lin Rui-zhi Wang Yi-guang Cheng Liang-liang Zhao Zhi-qiang Liang Jun-ru Wang Guan-jie Zhao Qing Gao Tian-zhi Zheng School of Equipment Engineering Shenyang Ligong University

CFRP/Al HC SPs(Carbon Fiber Reinforced Plastic/Aluminum Honeycomb Sandwich Panels)composite structures are widely used in the aerospace and many other fields due to their excellent performances. In order to reveal profoundly the dynamic response characteristics of CFRP/Al HC SPs composite structure under high-velocity impact loading, the experiments about aluminum honeycomb core and CFRP/Al HC SPs composite structure impacted by high-velocity projectiles have been performed by using a one-stage light gas gun loading and a high-speed camera systems, respectively. The whole physical process of collision is analyzed by using TEMA software which is provided by high-speed camera's manufacturer,and the pictures and related physical parameters of the projectile passing through the different layers at the key moments are extracted based on the set frame rate of the video. Meanwhile, the ABAQUS/Explicit module was used to conduct numerical simulation under the same conditions as the experiments, and extracting the pictures and related physical parameters during the projectile penetrating through aluminum honeycomb core and the sandwich panels at the different key moments. The results show that the durations of action for the projectile impacting the Al HC core and the CFRP/Al HC SPs at the velocity about 280 m/s were 86 μs and 240 μs in experiments, respectively, and the durations of action were 90.7μs and 236.2 μs at the same experimental conditions in numerical simulation, which were basically consistent comparing the experimental to simulated results. Moreover, more than 70% for the kinetic energy of the projectile consumed by the sandwich panels was attributed to the front panel and the aluminum honeycomb core during the entire impact process, and all these have verified the reliability of the numerical simulation.

关键词： ABAQUS/Explicit Duration of action between projectile and target Energy absorption

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Intersection of two rare conditions:Clinical reflection on tuberous sclerosis combined with primary lymphedema

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World Journal of Clinical Cases 2025年第7期13卷 13-16页

作者： Xiao Wu Xiao-hui min Hai-feng Xu M Jalal Ud Din Gang Zhang Department of Neurology Children's Hospital of Nanjing Medical UniversityNanjing 210008Jiangsu ProvinceChina Department of Pediatrics Peking University Shenzhen HospitalShenzhen 518036Guangdong ProvinceChina Nanjing Medical University Nanjing 210000Jiangsu ProvinceChina

This editorial discusses a case report recently published in the World Journal of Clinical *** report describes the clinical presentation,imaging,diagnosis,and treatment of a patient with tuberous sclerosis complex(TSC)combined with primary lymphedema(PLE).Additionally,it retrospectively analyzes the data of 16 previously reported cases of children with TSC combined with PLE to summarize the epidemiology,genetic diagnosis,and current main treatments of these *** report also speculates on the pathological and physiological mechanisms underlying TSC combined with *** combined with PLE is rare;therefore,the report provides a theoretical basis for understanding the pathophysiological mechanisms and treatment options for patients with TSC and *** clinical management of TSC is essential due to the diverse and multiorgan nature of its manifestations,often requiring a multidisciplinary approach for newly diagnosed cases.

关键词： Tuberous sclerosis complex Lymphedema Examination Diagnosis Treatment

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磁珠固定多抗预测最大吸附活性识别阳性突变体

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西安交通大学学报（医学版） 2017年第5期38卷 753-757,767页

作者：种慧敏冯一然杨晓兰廖飞重庆医科大学检验医学院临床检验诊断学教育部重点实验室重庆400016

目的考察磁珠固定多抗吸附细胞裂解液中酶/突变体,分析吸附酶活性对样品蛋白量响应曲线预测最大吸附活性(Vs)用于比较识别阳性突变体的可靠性。方法纯化重组表达大肠杆菌碱性磷酸酶(ECAP)及绿脓杆菌芳香硫酸酯酶(PAAS)为免疫原;兔抗血清... 详细信息

目的考察磁珠固定多抗吸附细胞裂解液中酶/突变体,分析吸附酶活性对样品蛋白量响应曲线预测最大吸附活性(Vs)用于比较识别阳性突变体的可靠性。方法纯化重组表达大肠杆菌碱性磷酸酶(ECAP)及绿脓杆菌芳香硫酸酯酶(PAAS)为免疫原;兔抗血清用33%硫酸铵分级和DEAE-纤维素层析纯化得多抗。磁珠羧基活化后固定多抗;用对硝基酚显色底物,碱终止后测定405nm吸收增量反映酶活性;分析吸附响应曲线预测Vs。结果多抗磁珠吸附酶的容量约2.0mg/g磁珠。ECAP比活性超过PAAS比活性70倍。ECAP突变体R168K较野生型比活性提高约50%,用2.5μg多抗磁珠反应10min即可预测Vs识别此阳性突变体;用PAAS突变体G138S为起始酶,用10μg多抗磁珠测定吸附酶反应20min后吸收预测Vs,能识别活性提高20%以上的PAAS弱阳性突变体。结论只要被吸附酶活性能可靠测定,优化磁珠固定多抗的用量能预测低活性酶/突变体Vs进行比较识别阳性突变体。

关键词：多抗突变体最大吸附活性预测磁珠

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创业团队文化多样性对创业绩效影响的实证研究

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中国林业经济 2018年第5期 98-102页

作者：李慧敏林凤上海理工大学管理学院上海200093

以创业资源整合能力为调节变量,分析创业团队文化多样性、创业绩效和创业资源整合能力三者的相关关系。通过对以往创业团队文化多样性、创业资源整合能力还有创业绩效相关的理论分析为基础,分析了资源整合能力对两者关系的影响,运用SPSS... 详细信息

以创业资源整合能力为调节变量,分析创业团队文化多样性、创业绩效和创业资源整合能力三者的相关关系。通过对以往创业团队文化多样性、创业资源整合能力还有创业绩效相关的理论分析为基础,分析了资源整合能力对两者关系的影响,运用SPSS22.0统计软件对数据进行描述性分析、信、效度检验、回归分析、调节作用分析,对研究假设进行检验并对研究结果进行分析讨论,从创业团队文化多样性、创业资源整合能力的视角提出了相关优化策略。

关键词：企业管理创业团队实证研究创业绩效

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Pancreatic stent improves the success rate of needle-knife papillotomy in patients with difficult biliary cannulation

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World Journal of Gastroenterology 2025年第1期31卷 58-67页

作者： Mu-Hsien Lee Cheng-hui Lin Chi-Huan Wu Yung-Kuan Tsou Kai-feng Sung Sheng-Fu Wang Nai-Jen Liu Department of Gastroenterology and Hepatology Chang Gung Memorial Hospital and Chang Gung University College of MedicineTaoyuan 33305Taiwan School of Medicine Chang Gung UniversityTaoyuan 33305Taiwan

BACKGROUND Needle-knife precut papillotomy(NKP)is typically performed ***,it remains unclear whether pancreatic stent(PS)placement can improve the outcomes of *** To explore whether PS placement improves the success rate of NKP in patients with difficult biliary *** This single-center retrospective study included 190 patients who underwent NKP between January 2017 and December 2021 after failed conventional biliary *** cases with incidental pancreatic duct cannulation during conventional biliary cannulation,the decision for pre-NKP PS placement was made at the endoscopist's *** primary outcome was the difference in the NKP success rate between patients with and without PS placement;the secondary outcome was the adverse event *** Among the 190 participants,82 received pre-NKP PS(PS-NKP group)whereas 108 did not[freehand or freehand NKP(FH-NKP)group].Post-NKP selective biliary cannulation was successful in 167(87.9%)patients,and the PS-NKP had a significantly higher success rate than the FH-NKP group(93.9%vs 83.3%,P=0.027).The overall adverse event rates were 7.3%and 11.1%in the PS-NKP and FH-NKP groups,respectively(P=0.493).A periampullary diverticulum(PAD)and significant intraoperative bleeding during NKP were independently associated with NKP failure;however,a pre-NKP PS was the only predictor of NKP *** the 44 participants with PADs,the PS-NKP group had a non-significantly higher NKP success rate than the FH-NKP group(87.5%and 65%,respectively;P=0.076).CONCLUSION PS significantly improved the success rate of NKP in patients with difficult biliary cannulation.

关键词： Difficult biliary cannulation Endoscopic retrograde cholangiopancreatography Needle-knife papillotomy Pancreatic stent Selective biliary cannulation

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Negative efficacy of antidepressants in pharmacotherapy of child and adolescent depression

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World Journal of Psychiatry 2025年第1期15卷 32-36页

作者： min Xu Hai-Ying Jin feng-Li Sun Wei-Dong Jin Department of Psychiatry Zhejiang Chinese Medical UniversityHangzhou 310053Zhejiang ProvinceChina Department of Psychiatry Tongde Hospital of Zhejiang ProvinceHangzhou 310012Zhejiang ProvinceChina Department of Psychiatry Zhejiang Provincial Mental Health CenterHangzhou 311122Zhejiang ProvinceChina

Antidepressants are the main drugs used to treat depression,but they have not been shown to be effective in the treatment of child and adolescent ***,many adolescent depression treatment guidelines still recommend the use of antidepressants,especially specific serotonin re-uptake *** studies have suggested that antidepressants have little therapeutic effect but many side effects,such as switching to mania,suicide,and non-suicidal self injury(NSSI),in the treatment of child and adolescent *** the process of developing guidelines,drug recommendations should not only focus on impro-ving symptoms,but they should also consider potential side *** review discusses the serious side effects of antidepressants,including switching to mania,suicide,and NSSI.

关键词： Child depression Adolescent depression Antidepressant Switch Suicide Non-suicidal self injury

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Activin A receptor type 1C single nucleotide polymorphisms associated with esophageal squamous cell carcinoma risk in Chinese population

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 39-51页

作者： Si-Yun Lin Hou Huang Jin-Jie Yu feng Su Tian Jiang Shao-Yuan Zhang Lu Lv Tao Long hui-Wen Pan Jun-Qing Qi Qiang Zhou Wei-feng Tang Guo-Wen Ding Li-ming Wang Li-Jie Tan Jun Yin Department of Thoracic Surgery Zhongshan Hospital Affiliated to Fudan UniversityShanghai 200032China Shanghai Key Laboratory of Clinical Geriatric Medicine Huadong Hospital Affiliated to Fudan UniversityShanghai 200040China Department of Cardiothoracic Surgery The Affiliated People's Hospital of Jiangsu UniversityZhenjiang 212002Jiangsu ProvinceChina Department of Thoracic Surgery Sichuan Cancer Hospital&InstituteChengdu 610042Sichuan ProvinceChina Department of Cardiothoracic Surgery Nanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical SchoolNanjing 210000Jiangsu ProvinceChina Department of Respiratory and Critical Care Medicine Shanghai Xuhui Central HospitalShanghai 200032China

BACKGROUND Transforming growth factor-β(TGF-β)superfamily plays an important role in tumor progression and *** A receptor type 1C(ACVR1C)is a TGF-βtype I receptor that is involved in tumorigenesis through binding to dif-ferent *** To evaluate the correlation between single nucleotide polymorphisms(SNPs)of ACVR1C and susceptibility to esophageal squamous cell carcinoma(ESCC)in Chinese Han *** In this hospital-based cohort study,1043 ESCC patients and 1143 healthy controls were *** SNPs(rs4664229,rs4556933,rs77886248,rs77263459,rs6734630)of ACVR1C were assessed by the ligation detection reaction ***-Weinberg equilibrium test,genetic model analysis,stratified analysis,linkage disequi-librium test,and haplotype analysis were *** Participants carrying ACVR1C rs4556933 GA mutant had significantly decreased risk of ESCC,and those with rs77886248 TA mutant were related with higher risk,especially in older male *** the haplotype analysis,ACVR1C Trs4664229Ars4556933Trs77886248Crs77263459Ars6734630 increased risk of ESCC,while Trs4664229Grs4556933Trs77886248Crs77263459Ars6734630 was associated with lower susceptibility to *** ACVR1C rs4556933 and rs77886248 SNPs were associated with the susceptibility to ESCC,which could provide a potential target for early diagnosis and treatment of ESCC in Chinese Han population.

关键词： Activin A receptor type 1C Single nucleotide polymorphisms Esophageal squamous cell carcinoma Genetic susceptibility Hospital-based cohort study

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Microplastic and nanoplastic exposure and risk of diabetes mellitus

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World Journal of Clinical Cases 2025年第3期13卷 24-29页

作者： hui-Yi Hsiao Chung-Yi Nien Ruei-feng Shiu Wei-Chun Chin Tzung-Hai Yen Department of Biomedical Sciences College of MedicineChang Gung UniversityTaoyuan 33302TaiwanChina Center for Tissue Engineering Chang Gung Memorial HospitalLinkouTaoyuan 33305TaiwanChina Department of Life Sciences National Central UniversityZhongli 320317TaoyuanTaiwanChina Center of Excellence for The Oceans Taiwan Ocean UniversityKeelung 20224TaiwanChina Institute of Marine Environment and Ecology Taiwan Ocean UniversityKeelung 20224TaiwanChina Department of Chemical and Materials Engineering University of California MercedMercedCA 95343United States Department of Nephrology Clinical Poison CenterChang Gung Memorial HospitalLinkou 33305TaoyuanTaiwanChina School of Traditional Chinese Medicine College of MedicineChang Gung UniversityTaoyuan 33302TaiwanChina

The issue of plastic pollutants has become a growing *** microplastics(MPs)(particle size<5 mm)and nanoplastics(NPs)(particle size<1μm)can cause DNA damage,cytotoxicity,and oxidative stress in various *** primary kno... 详细信息

The issue of plastic pollutants has become a growing *** microplastics(MPs)(particle sizeminants and MPs/NPs,supported by evidence from animal studies and the various chemical compositions of MPs/NPs.

关键词： Microplastics Nanoplastics Plastic pollution,Diabetes mellitus Insulin resistance

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An Efficient Boron Source Activation Strategy for the Low‑Temperature Synthesis of Boron Nitride Nanotubes

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Nano-Micro Letters 2025年第1期17卷 548-558页

作者： Ying Wang Kai Zhang Liping Ding Liyun Wu Songfeng E Qian He Nanyang Wang hui Zuo Zhengyang Zhou feng Ding Yue Hu Jin Zhang Yagang Yao National Laboratory of Solid State Microstructures College of Engineering and Applied SciencesJiangsu Key Laboratory of Artificial Functional Materialsand Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210093People’s Republic of China School of Electronic Information and Artificial Intelligence Shaanxi University of Science&TechnologyXian 710000People’s Republic of China College of Bioresources Chemical and Materials Engineering Shaanxi University of Science&TechnologyXian 710000People’s Republic of China Key Laboratory of Carbon Materials of Zhejiang Province College of Chemistry and Materials EngineeringWenzhou UniversityWenzhou 325000People’s Republic of China Shenzhen Institutes of Advanced Technology Chinese Academy of SciencesShenzhen 518000People’s Republic of China College of Chemical and Molecular Engineering Peking UniversityBeijing 100871People’s Republic of China

Lowering the synthesis temperature of boron nitride nanotubes(BNNTs)is crucial for their *** primary reason for adopting a high temperature is to enable the effective activation of highmelting-point solid *** this study,we developed a novel approach for efficiently activating boron by introducing alkali metal compounds into the conventional MgO–B *** approach can be adopted to form various low-melting-point AM–Mg–B–O growth *** growth systems have improved catalytic capability and reactivity even under low-temperature conditions,facilitating the synthesis of BNNTs at temperatures as low as 850℃.In addition,molecular dynamics simulations based on density functional theory theoretically demonstrate that the systems maintain a liquid state at low temperatures and interact with N atoms to form BN *** findings offer novel insights into the design of boron activation and are expected to facilitate research on the low-temperature synthesis of BNNTs.

关键词： Boron nitride nanotubes Low-temperature Boron activation Density functional theory

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转基因玉米SW12-859的抗螟性及农艺性状评价

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玉米科学 2017年第5期25卷 45-48页

作者：康领生姜志磊刘洋王玉民徐惠风吉林省农业科学院长春130033 吉林农业大学农学院长春130118

SW12-859为吉林省农业科学院农业生物技术研究所培育的转基因玉米杂交组合,全株表达Cry1F基因杀虫蛋白。本研究以其为材料,与其遗传背景相似的郑单958为非转基因对照,在玉米心叶期(6~8叶期)和穗期(13~16叶期)进行田间人工接玉米螟初孵幼... 详细信息

SW12-859为吉林省农业科学院农业生物技术研究所培育的转基因玉米杂交组合,全株表达Cry1F基因杀虫蛋白。本研究以其为材料,与其遗传背景相似的郑单958为非转基因对照,在玉米心叶期(6~8叶期)和穗期(13~16叶期)进行田间人工接玉米螟初孵幼虫,调查其抗螟性、农艺性状及对产量损失的影响。结果表明,在玉米心叶期和穗期,转基因玉米SW12-859对一、二代玉米螟表现为高抗,郑单958表现为感,二者受玉米螟危害程度(抗螟性)差异显著。转基因玉米SW12-859和郑单958的株高、穗位高等农艺性状相近,在接虫条件下,转基因玉米产量显著高于非转基因玉米。

关键词：玉米 CrylF基因亚洲玉米螟

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