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Computers, Materials & Continua 2020年第1期62卷 443-458页

作者： Yong-An Jung min-goo kang Young-Hwan You Department of Computer Engineering Sejong UniversitySeoulKorea Department of IT Contents Hanshin UniversityGyeonggi-doKorea

Device-to-device(D2D)communication is considered as a major challenge in the long term evolution(LTE)network wherein devices directly communicate with each *** of the key challenges in D2D sidelink is reliable and reduced-complexity *** address this issue,a computationally efficient sequential detection scheme for integer carrier frequency offset and sidelink identity is proposed in the LTE-D2D *** perform the frequency offset detection without retrieving the sidelink identity,the conjugate relation between two primary sidelink synchronization sequences is exploited,which facilitates the detection tasks of frequency offset and sidelink identity to be *** is demonstrated from simulation results that the inherent property of the sidelink synchronization sequences is effectively used for joint detection of frequency offset and sidelink identity with significantly reduced complexity,compared to existing estimation schemes.

关键词： Long term evolution device-to-device communication carrier frequency offset sidelink identity sidelink synchronization

A Strategy of Signal Detection for Performance Improvement in Clipping Based OFDM System

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Computers, Materials & Continua 2020年第7期64卷 181-191页

作者： Jae-Hyun Ro Won-Seok Lee min-goo kang Dae-Ki Hong Hyoung-Kyu Song Department of Information and Communication Engineering Sejong UniversitySeoulKorea Department of IT Contents Hanshin UniversityOsan-siKorea Department of System Semiconductor Engineering SangMyung UniversityCheonan-si31066Korea

In this paper,the supervised Deep Neural Network(DNN)based signal detection is analyzed for combating with nonlinear distortions efficiently and improving error performances in clipping based Orthogonal Frequency Division Multiplexing(OFDM)*** of the main disadvantages for the OFDM is the high Peak to Average Power Ratio(PAPR).The clipping is a simple method for the PAPR ***,an effect of the clipping is nonlinear distortion,and estimations for transmitting symbols are difficult despite a Maximum Likelihood(ML)detection at the *** DNN based online signal detection uses the offline learning model where all weights and biases at fully-connected layers are set to overcome nonlinear distortions by using training data ***,this paper introduces the required processes for the online signal detection and offline learning,and compares error performances with the ML detection in the clipping-based OFDM *** simulation results,the DNN based signal detection has better error performance than the conventional ML detection in multi-path fading wireless *** performance improvement is large as the complexity of system is increased such as huge Multiple Input Multiple Output(MIMO)system and high clipping rate.

关键词： Clipping DNN ML nonlinear distortion OFDM

Generation of double knockout cattle via CRISPR-Cas9 ribonucleoprotein(RNP)electroporation

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Journal of Animal Science and Biotechnology 2024年第1期15卷 456-462页

作者： Gyeong-min Gim Kyeong-Hyeon Eom Dong-Hyeok Kwon Dae-Jin Jung Dae-Hyun Kim Jun-Koo Yi Jae-Jung Ha Ji-Hyun Lee Seong-Beom Lee Woo-Jae Son Soo-Young Yum Won-Wu Lee goo Jang Laboratory of Theriogenology and Biotechnology Department of Veterinary Clinical ScienceCollege of Veterinary Medicine and the Research Institute of Veterinary ScienceSeoul National UniversitySeoulRepublic of Korea LARTBio Co. Ltd.SeoulRepublic of Korea Gyeongsangbukdo Livestock Research Institute YeongjuRepublic of Korea Comparative Medicine Disease Research Center Seoul National UniversitySeoulRepublic of Korea

Background Genome editing has been considered as powerful tool in agricultural ***,genome editing progress in cattle has not been fast as in other mammal species,for some disadvantages including long gestational periods,single pregnancy,and high raising ***,technically demanding methods such as microinjection and somatic cell nuclear transfer(SCNT)are needed for gene editing in *** this point of view,electroporation in embryos has been risen as an *** First,editing efficiency of our electroporation methods were tested for *** of mutation on embryo was confirmed by T7E1 *** first combination,mutation rates for MSTN and PRNP were 57.6%±13.7%and 54.6%±13.5%,*** case of MSTN/BLG,mutation rates were 83.9%±23.6%for MSTN,84.5%±18.0%for ***,the double-KO embryos were transferred to surrogates and mutation rate was identified in resultant calves by targeted deep *** recipients were transferred for MSTN/PRNP,4 calves were delivered,and one calf underwent an induction for double *** surrogates were given double-KO embryos for MSTN/BLG,and four of the six calves that were born had mutations in both *** These data demonstrated that production of genome edited cattle via electroporation of RNP could be effectively ***,MSTN and PRNP from beef cattle and MSTN and BLG from dairy cattle have been born and they will be valuable resources for future precision breeding.

关键词： Beta-lactoglobulin Cattle CRISPR-Cas9 Electroporation Knockout MSTN PRNP

Simple technique for the rescue and refixation of a partially disenclavated retropupillary iris claw intraocular lens

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International Journal of Ophthalmology(English edition) 2020年第11期13卷 1833-1835页

作者： Hyun goo kang Jae Yong Han Sung Chul Lee min Kim Department of Ophthalmology Institute of Vision ResearchGangnam Severance HospitalYonsei University College of Medicine211 EonjuroGangnam-guSeoul 06273Republic of Korea Department of Ophthalmology Institute of Vision ResearchSeverance Eye HospitalYonsei University College of Medicine50-1 Yonsei-roSeodaemun-guSeoul 03722Republic of Korea

Dear Editor,We would like to introduce a simple technique for the efficient rescue and refixation of a subluxated retropupillary iris claw intraocular lens(RPICIOL;Artisan■Aphakia model 205,Ophtec BV,Groningen,the Netherlands).The RPICIOL is a suture-less,posterior iris-fixated,polyinethyl methacrylate intraocular lens(IOL)that has gained widespread recognition and expanding use because of its efficiency in management of aphakia,combined with long-term intraocular safety and excellent sustained visual outcomes11 Postoperative dislocation/disenclavation of the RPICIOL may occur spontaneously or following trauma,with a rate reportedly between 0 to 10%[4-6].

关键词： law gained sustained

A modified,simple technique for internal limiting membrane free flap transplantation in macular hole surgery:the Peel-PFCL-Peel technique

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International Journal of Ophthalmology(English edition) 2021年第10期14卷 1636-1638页

作者： Hyun goo kang Jae Yong Han Jae Won Jun min Kim Department of Ophthalmology Institute of Vision ResearchGangnam Severance HospitalYonsei University College of Medicine211 EonjuroGangnam-guSeoul 06273Republic of Korea

Dear Editor,We would like to introduce a simple but modified variant perfluorocarbon liquid(PFCL)-assisted technique,namely the"Peel-PFCL-Peel"technique,which overcomes these difficulties while improving manipulation ... 详细信息

关键词： modified limiting overcome

Intraoperative optical coherence tomography findings during surgery for optic disc pit-associated maculopathy

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International Journal of Ophthalmology(English edition) 2020年第4期13卷 684-686页

作者： Hyun goo kang Sung Eun Park Eun Young Choi Sung Chul Lee min Kim Department of Ophthalmology Institute of Vision ResearchGangnam Severance HospitalYonsei University College of Medicine211 EonjuroGangnam-guSeoul 06273Republic of Korea Department of Ophthalmology Institute of Vision ResearchSeverance HospitalYonsei University College of Medicine134 Shinchon-dongSeodaemun-guSeoul 06273Republic of Korea

Dear Editor,We report our experience using a continuous intraoperative optical coherence tomography(OCT)-enabled microscope system for real-time anatomical evaluation of the optic pit during surgery in an 8-year-old girl who presented with symptomatic optic disc pit(ODP) maculopathy. ODP is an extremely rare congenital anomaly secondary to colobomatous malformation of the optic nerve head, with a reported incidence of 0.00009%[1]. Although patients are frequently asymptomatic, approximately 40%-50% of patients experience visual symptoms because of subretinal fluid(SRF) accumulation beneath the macula.

关键词： surgery maculopathy congenital

Fabrication of Near Net Shape Metallic Foam via Plaster Mould

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Journal of Materials Science & Technology 2008年第3期24卷 335-339页

作者： Young-Hwan Song Hwan-goo Seon Soo-Han Parka min-Jae Jeong Bo-Young Hur i-Cube Center School of Nano and Advanced Materials EngineeringGyeongsang National University ERIC School of Nano and Advanced Materials EngineeringGyeongsang National University

Fabrication characteristics are unstable in direct foaming method. Therefore, most of near net-shape metallic foams are produced, and investigated by powder metallurgy. Direct foaming method, however, has many benefits （i.e. reduce the unit cost of goods and fabrication process etc.） to fabrication of metallic foams. In this article, the fabrication characteristic of near net-shape metallic foams by direct foaming method was evaluated. Al and Plaster was used for base material and mould material respectively. Ca and TiH2 were added to molten Al as thickening and blowing agent for stable condition of bubbles. Thickening time was about 10 min with a stirring speed of 600 r/min. Foaming time was 30-120 s for evaluation of the optimum foaming condition. Amount of agent was selected by pre-experimental data. Porosity of near net-shape goods was measured by Archimedes method. On the other hand, it seems that increasing poring time and thickening agent make the poor porosity

关键词： Metal foam Near net shape foam Porosity

Taraxacum offlcinale protects against cholecystokinin-induced acute pancreatitis in rats

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World Journal of Gastroenterology 2005年第4期11卷 597-599页

作者： Sang-Wan Seo Hyun-Na Koo Hyo-Jin An kang-Beom Kwon Byung-Cheal Lim Eun-A Seo Do-Gon Ryu goo Moon Hong-Yeoul Kim Hyung-min Kim Seung-Heon Hong Department of Pharmacology College of Oriental Medicine Kyung Hee UniversitySeoul South Korea Department of Oriental PharmacyCollege of PharmacyWonkwang University Iksan Jeonbuk South Korea Department of Pharmacology College of Oriental Medicine Kyung Hee University Seoul South Korea Department of Pharmacology College of Oriental Medicine Kyung Hee University Seoul South Korea Department of Oriental PharmacyCollege of Pharmacy Wonkwang University Iksan Jeonbuk South Korea School of Oriental Medicine Wonkwang University IksanJeonbukSouth Korea Department of Food and Nutrition School of Human Environmental Science Wonkwang UniversityJeonbukSouth Korea Institute of Oriental Medicine College of Oriental Medicine Kyung Hee University SeoulSouth Korea Department of Pharmacology College of Oriental Medicine Kyung Hee UniversitySeoulSouth Korea Department of Oriental Pharmacy College of Pharmacy Wonkwang UniversityIksanJeonbukSouth Korea

AIM: Taraxacum officinale (TO) has been frequently used as a remedy for inflammatory diseases. The aim of this study was to investigate the effect of TO on cholecystokinin (CCK)-octapeptide-induced acute pancreatitis in ***: TO at 10 mg/kg was orally administered, followed by 75 μg/kg CCK octapeptide injected subcutaneously three times after 1, 3 and 5 h. This whole procedure was repeated for 5 d. We determined the pancreatic weight/body weight ratio, the levels of pancreatic HSP60 and HSP72, and the secretion of pro-inflammatory cytokines. Repeated CCK octapeptide treatment resulted in typical laboratory and morphological changes of experimentally-induced ***: TO significantly decreased the pancreatic weight/body weight ratio in CCK octapeptide-induced acute pancreatitis. TO also increased the pancreatic levels of HSP60 and HSP72. Additionally, the secretion of IL-6 and TNF-α decreased in the animals treated with ***: TO may have a protective effect against CCK octapeptide-induced acute pancreatitis.

关键词： Acute pancreatitis Taraxacum officinale CCK octapeptide

Real-time electrical detection of epidermal skin MoS2 biosensor for point-of-care diagnostics

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Nano Research 2017年第3期10卷 767-775页

作者： Geonwook Yoo Heekyeong Park minjung Kim Won Geun Song Seokhwan Jeong min Hyung Kim Hyungbeen Lee Sang Woo Lee Young KiHong min goo Lee Sungho Lee Sunkook Kim School of Electronic Engineering Soongsil University Seou106978 Republic of Korea Multi-Functional Nano/Bio Electronics Lab. Kyung Hee University Gyeonggi 17104 Republic of Korea Department of Biomedical Engineering Yonsei University Wonju 26493 Republic of Korea Korea Electronics Technology Institute Gyeonggi 13488 Republic of Korea

Various approaches have been proposed for point-of-care diagnostics, and in particular, optical detection is preferred because it is relatively simple and fast. At the same time, field-effect transistor （FET）-based biosensors have attracted great attention because they can provide highly sensitive and label-free detection. In this work we present highly sensitive, epidermal skin-type point-of-care devices with system-level integration of flexible MOS2 FET biosensors, read-out circuits, and light-emitting diode （LEDs） that enable real-time detection of prostate cancer antigens （PSA）. Regardless of the physical forms or mechanical stress conditions, our proposed high-performance MoS2 biosensors can detect a PSA concentration of 1 ***-1 without specific surface treatment for anti-PSA immobilization on the MoS2 surface on which we characterize and confirm physisorption of anti-PSA using Kelvin probe force microscopy （KPFM） and tapping-mode atomic force microscopy （tm-AFM）. Furthermore, current modulation induced by the binding process was stably maintained for longer than 2-3 min. The results indicate that flexible MoS2-based FET biosensors have great potential for point-of-care diagnostics for prostate cancer as well as other biomarkers.

关键词： epidermal skin biomarker MoS2 biosensor real-time point-of-care diagnostics

The High Nitrogen Pressure Synthesis of Manganese Nitride

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Chinese Physics Letters 2012年第12期29卷 228-231页

作者： SI Ping-Zhan JIANG Wei WANG Hai-Xia ZHONG min GE Hong-Liang CHOI Chul-Jin LEE Jung-goo School of Materials Science and Engineering China Jiliang UniversityHangzhou 3100182Korea Institute of Materials ScienceChangwonGyeongnam641-831R.Korea

We report on the structural transformation and unique magnetic properties of manganese nitrides prepared by nitriding Mn under N_(2) pressures of up to 25 MPa with varying *** N_(2) pressure not only makes nitridation more efficient at lower temperatures,but also enhances the N-content in the nitride lattices,which were expanded with increasing *** N-rich nitrides,includingε-Mn_(4)N,ζ-Mn6N_(2).58 andη-Mn_(3)N_(2),exhibit unique thermal *** N-richε-phase exhibits much larger coercivity and lower saturation magnetization in comparison with theε-phase prepared under ambient N_(2) *** coercivity of the N-richζ-phase reaches up to 45054 A/m.A saturation magnetization as large as 31 Am^(2)/kg is observed in the N-richη-*** are quite different from the conventional antiferromagneticζ-andη-phase obtained under ambient N_(2) *** ascribe the unconventional magnetic properties of the nitrides to the lattice distortion originating from the N-enrichment.

关键词： transformation magnetization saturation