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Expression Pattern of the Hippo Pathway Effector TAZ in Cellular and Fibrotic Nonspecific Interstitial Pneumonia

Chinese Medical Journal 2018年第5期131卷 626-628页

作者： min-kyung yeo Hee Sun Park yeon Hee Park Choong-Sik Lee Geon Yoo Dong II Park Jeong Eun Lee Jae Young Moon Sung Soo Jung Ju Ock Kim Dahyun Kang Hyun Jin Cho min-Woong Kang Jin-Whan Kim Song-Soo Kim Chaeuk Chung Department of Pathology Chungnam National University School of Medicine Daejeon 35015 South Korea Division of Pulmonology Department of Internal Medicine Chungnam National University 282 Munhwaro Jung-gu Daejeon 35015 South Korea Department of Internal Medicine Daejeonst Mary's Hospital College of Medicine Catholic University Daejeon 34943 South Korea ~Department of Toxicological Evaluation and Research Korea Institute of Toxicology 141 Gajeong-ro Yuseong-gu Daejeon 34114 South Korea Department of Thoracic Surgery College of Medicine Chungnam National University Daejeon 35015 South Korea Department of Radiology College of Medicine Chungnam National University Daejeon 35015 South Korea Infection Control Convergence Research Center College of Medicine Chungnam National University Jung-guMunhwa-ro 266 Daejeon 35015 South Korea

Interstitial lung disease （ILD） is a comprehensive term referring to a group of lung diseases affecting the interstitium of the lung. Idiopathic pulmonary fibrosis （IPF） is the most common idiopathic ILD, and nonspecific interstitial pneumonia （NSIP） is the second most common. As the name suggests, NSIP is diagnosed atter many other diseases are excluded. The main pathological finding in NSIP is homogeneous interstitial inflammation with or without fibrosis. NSIP can be categorized by cellular type or fibrotic type, according to the grade of inflammation and fibrosis. The cellular type has mostly inflammatory lesions with good responses to steroid, but the fibrotic type has a large proportion of fibrosis mixed with inflammatory lesions and a relatively poor response to steroid treatment So far, the exact mechanism underlying idiopathic lED has not been clarified. Determining key regulators of these ILDs will be helpful in the diagnosis and development of novel drugs for ILD.

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Machine-learned wearable sensors for real-time hand-motion recognition: toward practical applications

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National Science Review 2024年第2期11卷 231-263页

作者： kyung Rok Pyun Kangkyu Kwon Myung Jin Yoo Kyun Kyu Kim Dohyeon Gong Woon-Hong yeo Seungyong Han Seung Hwan Ko Department of Mechanical Engineering Seoul National University IEN Center for Human-Centric Interfaces and Engineering Institute for Electronics and NanotechnologyGeorgia Institute of Technology School of Electrical and Computer Engineering Georgia Institute of Technology Department of Chemical Engineering Stanford University Department of Mechanical Engineering Ajou University George W.Woodruff School of Mechanical Engineering Georgia Institute of Technology Institute of Advanced Machinery and Design(SNU-IAMD) Seoul National University

Soft electromechanical sensors have led to a new paradigm of electronic devices for novel motion-based wearable applications in our daily lives. However, the vast amount of random and unidentified signals generated by complex body motions has hindered the precise recognition and practical application of this technology. Recent advancements in artificial-intelligence technology have enabled significant strides in extracting features from massive and intricate data sets, thereby presenting a breakthrough in utilizing wearable sensors for practical applications. Beyond traditional machine-learning techniques for classifying simple gestures, advanced machine-learning algorithms have been developed to handle more complex and nuanced motion-based tasks with restricted training data sets. Machine-learning techniques have improved the ability to perceive, and thus machine-learned wearable soft sensors have enabled accurate and rapid human-gesture recognition, providing real-time feedback to users. This forms a crucial component of future wearable electronics, contributing to a robust human–machine interface. In this review, we provide a comprehensive summary covering materials, structures and machine-learning algorithms for hand-gesture recognition and possible practical applications through machine-learned wearable electromechanical sensors.

关键词： wearable sensor soft electronics artificial intelligence machine learning human–machine interfaces gesture recognition

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Zn-doped nickel iron(oxy)hydroxide nanocubes passivated by polyanions with high catalytic activity and corrosion resistance for seawater oxidation

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Journal of Energy Chemistry 2023年第6期81卷 82-92,I0004页

作者： So Jung Kim Heechae Choi Jeong Ho Ryu Kang min Kim Sungwook Mhin Arpan Kumar Nayak Junghwan Bang minyeong Je Ghulam Ali kyung Yoon Chung Kyeong-Han Na Won-Youl Choi Sunghwan yeo Jin Uk Jang HyukSu Han Department of Energy Engineering Konkuk University120 Neungdong-roGwangjin-guSeoul 05029Republic of Korea Theoretical Materials&Chemistry Group Institute of Inorganic ChemistryUniversity of CologneGreinst.650939CologneGermany Materials Lab Geobuk-ro 25-50Incheon 22793Republic of Korea Department of Materials Science and Engineering Korea National University of Transportation50 Daehak-roChungjuChungbuk 27469Republic of Korea Korea Institute of Industrial Technology 137-41 Gwahakdanji-roGangneung-siGangwon 25440Republic of Korea Department of Advanced Materials Engineering Kyonggi UniversitySuwon 16227Republic of Korea Korea Institute of Industrial Technology 156 Gaetbeol-roYeonsu-guIncheon 406-840Republic of Korea U.S.-Pakistan Center for Advanced Studies in Energy(USPCASE) National University of Sciences and Technology(NUST)H-12IslamabadPakistan Energy Storage Research Center Korea Institute of Science and TechnologyHwarang-ro 14-gil 5Seongbuk-guSeoul 02792Republic of Korea Division of Energy and Environment Technology KIST SchoolKorea University of Science and TechnologySeoul 02792Republic of Korea Department of Metal and Materials Engineering Gangneung-Wonju National University 7 JukheongilGangneungGangwon 25457Republic of Korea Smart Hydrogen Energy Center Gangneung-Wonju National University7 JukheongilGangneungGangwon 25457Republic of Korea Innovative Fuel Development Division Korea Atomic Energy Research InstituteDaedeok-daero 989-111Yuseong-guDaejeon 305-353Republic of Korea

Electrochemical water splitting to produce hydrogen fuel is a promising renewable energy-conversion ***-scale electrolysis of freshwater may deplete water resources and cause water scarcity ***,seawater electrolysis is a potential solution to the future energy and water *** seawater electrolysis,it is critical to develop cost-effective electrocatalysts to split seawater without chloride ***,we present zinc-doped nickel iron(oxy)hydroxide nanocubes passivated by negatively charged polyanions(NFZ-PBA-S)that exhibits outstanding catalytic activity,stability,and selectivity for seawater *** dopants and polyanion-rich passivated surface layers in NFZ-PBA-S could effectively repel chlorine ions and enhance corrosion resistance,enabling its excellent catalytic activity and stability for seawater oxidation.

关键词： Seawater splitting Oxygen evolution reaction Electrocatalyst Layered double hydroxide Sulfidation

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Party Autonomy in the Choice of Law for Torts in Asia

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中国国际私法与比较法年刊 2017年第2期20卷 66-84页

作者： yeo Tiong min Asian Business Law Institute

Ⅰ.Introduction The role of party autonomy is grow ing apace in the sphere of international commercial disputes,as seen in the phenomenal development of international commercial arbitration and the emergent international acceptance of the Hague Convention on Choice of Court Agreements 2005,(1)as well as in the increasing significance of mediation for international disputes.

关键词： Choice acceptance autonomy

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Computed tomography and magnetic resonance imaging evaluation of lymph node metastasis in early colorectal cancer

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World Journal of Gastroenterology 2015年第2期21卷 556-562页

作者： Joonsung Choi Soon Nam Oh Dong-Myung yeo Won kyung Kang Chan-Kwon Jung Sang Woo Kim Michael Yong Park Department of Radiology Seoul St.Mary’s HospitalThe Catholic University of KoreaSeoul 137-701South Korea Department of Surgery Seoul St.Mary’s HospitalThe Catholic University of KoreaSeoul 137-701South Korea Department of Hospital Pathology Seoul St.Mary’s HospitalThe Catholic University of KoreaSeoul 137-701South Korea Department of Internal Medicine Seoul St.Mary’s HospitalThe Catholic University of KoreaSeoul 137-701South Korea

AIM: To assess the role of computed tomography(CT) and magnetic resonance imaging(MRI) and establish imaging criteria of lymph node metastasis in early colorectal ***: One hundred and sixty patients with early colorectal cancer were evaluated for tumor location, clinical history of polypectomy, depth of tumor invasion, and lymph node metastasis. Two radiologists assessed preoperative CT and/or MRI for the primary tumor site detectability, the presence or absence of regional lymph node, and the size of the largest lymph node. Demographic, imaging, and pathologic findings were compared between the two groups of patients based on pathologic lymph node metastasis and optimal size criterion was ***: The locations of tumor were ascending, transverse, descending, sigmoid colon, and rectum. One hundred and sixty early colorectal cancers were classified into 3 groups based on the pathological depth of tumor invasion; mucosa, submucosa, and depth unavailable. A total of 20(12.5%) cancers with submucosal invasion showed lymph node metastasis. Lymph nodes were detected on CT or MRI in 53 patients. The detection rate and size of lymph nodes were significantly higher(P = 0.000, P = 0.044, respectively) in patients with pathologic nodal metastasis than in patients without nodal metastasis. Receiver operating curve analysis showed that a cut-off value of 4.1 mm is optimal with a sensitivity of 78.6% and specificity of 75%.CONCLUSION: The short diameter size criterion of≥ 4.1 mm for metastatic lymph nodes was optimal for nodal staging in early colorectal cancer.

关键词： Early colon cancer Lymph node metastasis Computed

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A Unified Momentum Equation Approach for Computing Flow-Induced Stresses in Structures with Arbitrarily-Shaped Stationary Boundaries

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Communications in Computational Physics 2017年第6期22卷 39-63页

作者： Haram yeo Hyungson Ki Department of Mechanical Engineering Ulsan National Institute of Science and Technology(UNIST)50 UNIST-gilUlsan 44919South Korea

This article presents a novel monolithic numerical method for computing flow-induced stresses for problems involving arbitrarily-shaped stationary boundaries.A unified momentum equation for a continuum consisting of both fluids and solids is derived in terms of velocity by hybridizing the momentum equations of incompressible fluids and linear elastic *** at the interface are smeared over a finite thickness around the interface using the signed distance function,and the resulting momentum equation implicitly takes care of the interfacial conditions without using a body-fitted grid.A finite volume approach is employed to discretize the obtained governing equations on a Cartesian *** validation purposes,this method has been applied to three examples,lid-driven cavity flow in a square cavity,lid-driven cavity flow in a circular cavity,and flow over a cylinder,where velocity and stress fields are simultaneously obtained for both fluids and *** simulation results agree well with the results found in the literature and the results obtained by COMSOL Multiphysicsr.

关键词： Flow induced stress unified momentum equation monolithic approach smeared interface stationary boundary

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Laboratory characteristics of recent hepatitis A in Korea:Ongoing epidemiological shift

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World Journal of Gastroenterology 2010年第9期16卷 1115-1118页

作者： Hee Won Moon Jin Hee Cho mina Hur yeo-min Yun Won Hyeok Choe So Young Kwon Chang Hong Lee Department of Laboratory Medicine Konkuk University School of MedicineKonkuk University Medical Center Department of Internal Medicine Konkuk University School of MedicineKonkuk University Medical Center

AIM:To evaluate seroprevalence of hepatitis A virus (HAV) antibody and investigate demographic,clinical,and laboratory features of recent cases in ***:For the evaluation of hepatitis A seroprevalence,we analyzed the data from 3127 subjects including,healthcare workers and patients who visited Konkuk University Hospital,a secondary referral center,from January to October *** sera with positive IgM were excluded from seroprevalence data for total HAV *** retrospectively reviewed the electronic medical records of 419 patients with HAV,who were diagnosed by the presence of serum IgM antibodies against *** patients presented at Konkuk University Hospital between August 2005 and September ***:Among 3127 sera tested,1428 (45.7%)were positive for anti-HAV *** seroprevalence was very low in teenagers or those in their twenties,increased in those in their thirties,and was > 90% in older *** children younger than 10 years,seroprevalence was increased *** patients with HAV hepatitis were in their twenties and *** γ-glutamyl transpeptidase increased with age and was significantly higher in patients older than 30 *** of severity,such as decreased albumin and increased bilirubin,were also more prominent in the older age group;however,the leukocyte count was higher and the frequency of leukopenia was lower in younger patients than in older ***:There has been an apparent epidemiological shift in HAV seroprevalence and a change in the peak age of HAV *** study could provide baseline data of recent hepatitis A in Asia.

关键词： Hepatitis A virus Seroprevalence Epidemiology Korea

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新世纪韩国对华公共外交变迁研究——以韩剧为例

新世纪韩国对华公共外交变迁研究——以韩剧为例

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作者： LEE yeo kyung 厦门大学

学位级别：硕士

公共外交是指一国政府通过文化交流、信息项目等形式,了解、获悉情况和影响国外公众,以提高本国国家形象和国际影响力,进而增进本国国家利益的外交方式。公共外交与传统外交不同之处在于,前者以文化和意识形态等“软实力”为手段与外国... 详细信息

公共外交是指一国政府通过文化交流、信息项目等形式,了解、获悉情况和影响国外公众,以提高本国国家形象和国际影响力,进而增进本国国家利益的外交方式。公共外交与传统外交不同之处在于,前者以文化和意识形态等“软实力”为手段与外国人进行沟通。传统意义的公共外交是指一国政府与国外民众的外交形式,它的活动手段包括文化交流项目、国际广播和互联网等,其主要表达形式是信息和语言。而在当今日新月异的互联网时代,公众通过互联网等现代信息手段能够更广泛地参与到公共外交活动中来,或者有更多的公众行为具有公共外交效果。特别韩国的公共外交是除了中央政府推进的公共外交,民间也开展了多种形态的公共外交。这篇论文是公共外交理论的基本内容进行介绍,在此基础对韩国公共外交的基本情况进行概述,并阐述电视剧在韩国公共外交中的地位。以电视剧为例,分析韩国对华公共外交的发展演变过程,主要是分为四个阶段,分别是2000年至2005年,2006年至2010年,2011年至2015年,2016年至今。重点梳理每一个阶段韩国对华公共外交存在怎样的特点。探讨为什么会出现发展演变过程,影响韩国对华公共外交发展演变的因素有哪些?政治关系、经济贸易、文化政策等因素都可能会影响到上述的演变过程。因此,论文要分析韩国对中国公共外交的模式和韩国公共外交的特征,以及公共外交的文化交流对两国产生了什么样的影响、潜在的问题是什么、还有公共外交发展的现状和对政治、经济、文化的影响的研究,并对公共外交推进的现状进行了分析,探索其方向发展。通过分析本文认为在对中国韩剧公共外交中,政治关系友好是公共外交开展的前提,经济贸易频繁是公共外交发展的动力,文化政策规范是公共外交持续的力量。

关键词：公共外交软实力中韩关系韩剧传播

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Development of systemic therapy for hepatocellular carcinoma at 2013:Updates and insights

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World Journal of Gastroenterology 2014年第12期20卷 3135-3145页

作者： Stephen L Chan Winnie yeo Department of Clinical Oncology The Chinese University of Hong KongPrince of Wales Hospital State Key Laboratory in Oncology in South China

A growing number of multi-targeted tyrosine kinase inhibitor (TKI) has undergone testing for hepatocellular carcinoma (HCC). Unfortunately, this enthusiasm has recently been discouraged by a number of negative phase III studies on several anti-angiogenic TKIs in HCC. Several postulations have been made to account for this phenomenon, namely the plateau effects of anti-angiogenesis approach, the heterogeneity of HCC in terms of background hepatitis/cirrhosis and tumor biology, as well as the way how clinical trials are designed. Regardless of the underlying reasons, these results suggested that alternative strategies are necessary to further develop systemic therapy for HCC. Several new strategies are currently evaluated: for examples, molecular agents with activities against targets other than vascular endothelial growth factor receptor are being evaluated in on-going clinical trials. In addition, different approaches of targeted agents in combination with various treatment modalities, such as concurrently with another molecular agent, cytotoxic chemotherapy or transarterial chemoembolization, are being developed. This review aims to give a summary on the results of recently released clinical trials on TKIs, followed by discussion on some of the potential novel agents and combinational approaches. Future directions for testing innovative systemic agents for HCC will also be discussed.

关键词： Liver neoplasms Systemic treatment Biologics Staging Clinical trial

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Hemorrhoidectomy- making sense of the surgical options

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World Journal of Gastroenterology 2014年第45期20卷 16976-16983页

作者： Danson yeo Kok-Yang Tan Department of Surgery Alexandra Health Khoo Teck Puat Hospital

While debate continues as to which is the best surgical method for the treatment of hemorrhoids, none of the currently available surgical methods approach the ideal surgical option, which is one that is effective while being safe and painless. In reality, the less painful the procedure, the more likely it is to be associated with recurrence post-op. Where hemorrhoids surgery is concerned, there isn’t a “one size fits all” option. Most of the randomized controlled trials performed to date include hemorrhoids of various grades and with a focus on only comparing surgical methods while failing to stratify the outcomes according to the grade of hemorrhoid. We believe that surgery needs to be tailored not only to the grade of the hemorrhoids, but also to the size, circumferential nature of the disease, and prevailing symptomatology.

关键词： Hemorrhoidectomy Doppler-guided hemorrhoidal artery ligation Stapler LigaSure Conventional

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