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Body distribution and in situ evading of phagocytic uptake by macrophages of long-circulating poly (ethylene glycol) cyanoacrylate-co-nhexadecyl cyanoacrylate nanoparticles

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Acta Pharmacologica Sinica 2005年第12期26卷 1512-1518页

作者： min huang wei wu~2 jun qian dan-jing wan xiu-li wei jian-hua zhu school of pharmacy,fudan university,shanghai 200032,china schoolofpharmacy FudanUniversityShanghai200032China

Aim:To investigate the body distribution in mice of[14C]-labeled polymethoxyethyleneglycol cyanoacrylate-co-n-hexadecyl cyanoacrylate(PEG-PHDCA)nanoparticles and in situ evading of phagocytic uptake by mouse peri-toneal ***:PEG-PHDCA copolymers were synthesized bycondensation of methoxypolyethylene glycol cyanoacetate with[14C]-hexadecyl-cyanoacetate.[14C]-nanoparticles were prepared using the nanoprecipitation/solvent diffusion method,while fluorescent nanoparticles were prepared by in-corporating rhodamine *** situ phagocytic uptake was evaluated by *** distribution in mice was evaluated by determining radioactivityin tissues using a scintillation ***:Phagocytic uptake by macroph-ages can be efficiently evaded by fluorescent PEG-PHDCA ***48 h,31% of the radioactivity of the stealth[14C]-PEG-PHDCA nanoparticles afteriv injection was still found in blood,whereas non-stealth PHDCA nanoparticleswere cleaned up from the bloodstream in a short *** distribution of stealthPEG-PHDCA nanoparticles and non-stealth PHDCA nanoparticals in mice waspoor in lung,kidney,and brain,and a little higher in *** accumula-tion was unusually high for both stealth and non-stealth nanoparticles,typical oflymphatic *** accumulation of stealth PEG-PHDCA nanoparticles in thespleen was 1.7 times as much as that of non-stealth PHDCA(Pliver was 0.8 times asmuch as that of non-stealth PHDCA(Plivery.

关键词： nanotechnology tissue distribution polyethylene glycols cynoacrylates polymers spleen

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CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves weiming An Rui An daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia hua Cai Wenyong Cai wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai huacheng Cai Lorenzo Calibbi junsong Cang Guofu Cao jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen mingjun Chen mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong jianin AGH university of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui university HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu university Institute of ScienceVaranasi Bandirma Onyedi Eylul university Bandirma Beihang university Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal university Beijing Brown university ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad university Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo university Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central china Normal university WuhanHubei Central South university ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan china academy of engineering physics MianyangSichuan china building materials academy Beijing china Center of Advanced Science and Technology Beijing china Institute of Atomic Energy Beijing china Jiliang university HangzhouZhejiang china Nuclear Instrument CO. LTDBeijing china university of Geosciences Beijing china university of Geosciences WuhanHubei china university of mining and Technology XuzhouJiangsu china West Normal university NanchongSichuan Chongqing university Department of PhysicsChongqing Chulalongkorn university Bangkok City university of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell university IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian minzu university DalianLiaoning Dalian university of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East china university Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by china,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

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Timing analysis of the black hole candidate EXO 1846–031 with Insight-HXMT monitoring

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Research in Astronomy and Astrophysics 2021年第3期21卷 193-204页

作者： He-Xin liu Yue huang Guang-Cheng Xiao Qing-Cui Bu Jin-Lu Qu Shu Zhang Shuang-Nan Zhang Shu-Mei Jia Fang-jun Lu Xiang Ma lian Tao wei Zhang li Chen li-ming Song Ti-Pei li Yu-Peng Xu Xue-Lei Cao Yong Chen Cong-Zhan liu Ce Cai Zhi Chang Gang Chen Tian-Xiang Chen Yi-Bao Chen Yu-Peng Chen wei Cui wei-wei Cui jing-Kang Deng Yong-wei Dong Yuan-Yuan Du min-Xue Fu Guan-hua Gao He Gao min Gao ming-Yu Ge Yu-Dong Gu Ju Guan Cheng-Cheng Guo Da-wei Han Jia Huo Lu-hua jiang wei-Chun jiang jing Jin Yong-Jie Jin ling-Da Kong Bing li Cheng-Kui li Gang li Mao-Shun li wei li Xian li Xiao-Bo li Xu-Fang li Yang-Guo li Zheng-wei li Xiao-hua liang jing-Yuan liao Bai-Sheng liu Guo-Qing liu Hong-wei liu Xiao-jing liu Yi-Nong liu Bo Lu Xue-Feng Lu Qi Luo Tao Luo Bin Meng Yi Nang jian-Yin Nie Ge Ou Na Sai Ren-Cheng Shang Xin-Ying Song liang Sun Ying Tan You-li Tuo Chen wang Guo-Feng wang Juan wang ling-jun wang Weng-Shuai wang Yu-Sa wang Xiang-Yang Wen Bai-Yang wu Bo-Bing wu Mei wu Shuo Xiao Shao-lin Xiong He Xu Jia-wei Yang Sheng Yang Yan-Ji Yang Yi-jung Yang Qi-Bin Yi qian-Qing Yin Yuan You Ai-Mei Zhang Cheng-Mo Zhang Fan Zhang Hong-Mei Zhang Juan Zhang Tong Zhang wan-Chang Zhang Wen-Zhao Zhang Yi Zhang Yi-Fei Zhang Yong-Jie Zhang Yuan-Hang Zhang Yue Zhang Zhao Zhang Zhi Zhang Zi-liang Zhang Hai-Sheng Zhao Xiao-Fan Zhao Shi-Jie Zheng Yao-Guang Zheng Deng-Ke Zhou jian-Feng Zhou Yu-Xuan zhu Ren-lin Zhuang Yue zhu Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China university of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China Institut fur Astronomie und Astrophysik Kepler Center for Astro and Particle PhysicsEberhard Karls Universität72076 TubingenGermany Department of Astronomy Beijing Normal UniversityBeijing 100088China Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China College of Physics Sciences&Technology Hebei UniversityBaoding 071002Hebei ProvinceChina

We present the observational results from a detailed timing analysis of the black hole candidate EXO 1846-031 during its outburst in 2019 with the observations of Insight-HXMT,NICER and *** outburst can be classified roughly into four different ***-C quasi-periodic oscillations(QPOs)observed by NICER(about 0.1-6 Hz)and Insight-HXMT(about 0.7-8 Hz)are also reported in this ***,we study various physical quantities related to QPO *** QPO rms-frequency relationship in the energy band 1-10 keV indicates that there is a turning pointing in frequency around2 Hz,which is similar to that of GRS 1915+105.A possible hypothesis for the relationship above may be related to the inclination of the source,which may require a high inclination to explain *** relationships between QPO frequency and QPO rms,hardness,total fractional rms and count rate have also been found in other transient sources,which can indicate that the origin of type-C QPOs is non-thermal.

关键词： X-ray binaries black hole candidate QPO EXO 1846–031

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Consensus statement on layout and delivery of automatic external defibrillator in china

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Journal of Hainan Medical university 2020年第15期26卷 18-23页

作者： Yu Cao Song Chen Yan-Fen Chai Xiao-Hui Chen Yu-Guo Chen Shao-Wen Cheng Wen-wei Cheng Bang-Han Ding Yang Deng Jie Fu Bang-jiang Fang Mai-Ying Fan li Gui Ping Gong wei Guo Shu-Bin Guo liang huang Ji-Yuan Han Zhong Ji Xian-Fei Ji Xin-Cai Ji Hong-Xu Jin Xin-jun jiang wang-Xiang jiang Jia-liang liu Xiao-Ran liu Zhi liu Chuan-zhu Lv Feng Lu Tan-Shi li Xin li Yong li Shang-Lun li Shuang-ming li Xiao-Gang li Bao-jun li Pei-wu li Chun-Sheng li Zhi-jun li Chang-Luo li Xiang-min li Yin-Ping li Zong-jun Lu Zu-Xun Lu Zhong-Qiu Lu Zhi-qian Luo Xiao-Xing liao jian-Bo Lei Tao Ma Yu Ma Yue-Feng Ma Qing-Bian Ma lin-Hao Ma jun-Qi Ma Shi-Nan Nie Jie-Miao Ou-Yang Peng Peng Qiao Pei Shu-ming Pan Guo-Zhong Qing li-Jie Qin wu-Ying Qiao Fei Shao wei Song Xing-Yue Song Zhen-Ju Song Rong-Ju Sun De-Ya Shang Du-Juan Sha Gui-Lan Tao Guo-Gang Tian Ying-Ping Tian jian-Guang Tian Chao-Yang Tong Zi-Ren Tang Meng-Xiong Tang Guo-Ping wu Zhi wan Tao wang Xin wang Peng wang Zhong wang Tong wang Ri-Xing wang Yi-Xin wang Xiao-dan wang ling wu wei wei hua Xiang Feng Xu jun Xu Jie Xu Miao-Rong Xie Shuo-Gui Xu Tie Xu Feng Yu Wen Yi li-Shan Yang Shi-Jiao Yan Jin-jian Yao Shou-Chun Yan Xue-Zhong Yu Xian-Zhi Ye Xian-liang Yan Fu-Bing Zhou Rong-Bin Zhou ming Zhou qiang Zhou Jin Zhou Ping Zhou Chang-Ju zhu hua-Dong zhu Ji-Hong zhu Hong Zhang Mao Zhang hua Zhang Na Zhang Guo-qiang Zhang Guo-xiu Zhang Jin-Song Zhang Wen-wu Zhang Wen-Zhong Zhang jian-Feng Zhang Yi-min zhu jun Zeng Yuan Zheng Zhi-Jie Zheng Shen Zhao Yan Zhao min Zhao Bin Zhao Xiao-Dong Zhao Xiao-jing Zhao Hong-Ke Zeng Sheng-qiang Zou The Chinese Society of Emergency Medicine Research Unit of Island Emergency Medicine Chinese Academy of Medical SciencesHainan Medical University Key Laboratory of Emergency and Trauma of ministry of Education Hainan Medical UniversityHaikouHainanChina Emergency and Trauma College Hainan Medical UniversityHaikouHainanChina Department of Emergency Hainan Clinical Research Center for Acute and Critical DiseasesThe Second Affiliated Hospital of Hainan Medical UniversityHaikouHainanChina Key Laboratory of Hainan Trauma and Disaster Rescue Key Laboratory of Trauma of Hainan Medical university

*** Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac *** is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in china[2].

关键词： cardiac death respiratory

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2017年中国ICU患者营养治疗实施状况横断面调查

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解放军医学杂志 2019年第5期44卷 388-393页

作者：邢娟章仲恒柯路周晶秦秉玉梁宏开陈晓梅刘文明刘忠民艾宇航王迪芬王秋卉周青山张福森钱克俭蒋东坡臧彬黎毅敏黄晓波曲彦谢颖光许东琳邹志强郑祥德刘建波郭丰梁亚风孙强高红梅刘阳常平程爱斌杨荣利么改琦孙昀王晓蓉张怡熊旭明于健孙荣青李志伟袁世荧宋云林高培阳刘海燕张朝辉吴允孚马标郭强山峰杨明施李海玲李圆菲鲁卫华王磊钱传云王智勇林建东张汝敏万鹏彭志勇龚裕强黄林喜伍国宝孙洁邓义军师东武周立新周发春石秦东郭晓东刘雪燕武卫东孟祥忠李连弟陈炜炜李树生万献尧曹志新张安古利明陈炜吴京兰周丽华张震环翁以炳封永顺杨春丽冯永健赵素民佟飞郝东韩辉付宝才巩传勇李志平胡琨琳寇秋野张晗刘洁樊楚明周新陈秀梅孙俊丽周学军宋斌孙诚赵丽芸董兴鲁张琳琳佟大为潘志国蔡常洁王东浩董英俊龚园其吴志松孟新科王平李维勤南京医科大学金陵临床医学院南京210002 无锡人民医院江苏无锡214001 北京市密云区医院北京101500 洛阳市中心医院河南洛阳471009 北京市怀柔区第一医院北京101400 陆军总医院北京100700 广东省人民医院广州510080 广东省第二中医院广州510095 北京中医医院北京100010 安徽省立医院西院区合肥230001 沈阳市第一人民医院沈阳110041 南部战区总医院广州510050 湖北省人民医院武汉430060 中山大学附属第一医院广州510080 天津市肿瘤医院天津300060 山西省肿瘤医院太原030000 南昌大学第二附属医院南昌330006 北京中医药大学东方医院北京100029 深圳第二人民医院广东深圳100730 成都市第五人民医院成都611130 泰安市中心医院山东泰安271000 南昌大学第一附属医院南昌330006 陆军军医大学大坪医院重庆400042 中国医科大学附属第二医院沈阳110004 广州医科大学附属第一医院广州510120 四川省人民医院成都610072 青岛市立医院青岛266071 济宁市第一人民医院山东济宁272000 浙江大学医学院附属邵逸夫医院杭州310016 广州市第一人民医院广州510000 福建医科大学附属协和医院福州350001 达州市中心医院四川达州635000 内蒙古自治区人民医院呼和浩特010017 烟台毓璜顶医院山东烟台264000 天津市人民医院天津300000 天津市第一中心医院天津300192 唐山市工人医院河北唐山063000 南方医科大学珠江医院广州510515 华北理工大学附属医院河北唐山063210 河南省人民医院郑州450003 大连市中心医院辽宁大连116033 北京大学第三医院北京100083 安徽医科大学第二附属医院合肥230601 温州医科大学附属第一医院浙江温州325000 陕西省人民医院西安710068 广州医科大学附属第二医院广州510120 大连医科大学附属第二医院辽宁大连116011 郑州大学第一附属医院郑州450052 昆明市第一人民医院昆明650011 华中科技大学同济医学院附属协和医院武汉430030 中山市人民医院广东中山528403 新疆医科大学第一附属医院乌鲁木齐830054 成都中医药大学附属医院成都610075 安徽医科大学第一附属医院合肥230032 宜昌市中心人民医院湖北宜昌443003 苏州市立医院东区江苏苏州215008 济宁医学院附属医院山东济宁272000 苏州大学附属第一人民医院江苏苏州215006 青岛大学医学院附属医院东院区山东青岛266071 中南大学湘雅三医院长沙410013 海军第971医院山东青岛266073 山东大学齐鲁医院济南250012 长沙市中心医院长沙410000 皖南医学院弋矶山医院安徽芜湖241002 山西医科大学第一医院太原030001 昆明医科大学第一附属医院昆明650032 河北医科大学第三医院石家庄050017 福建医科大学附属第一医院福州350004 淄博市中心医院山东淄博100085 宜昌市第一人民医院湖北宜昌443003 武汉大学中南医院武汉430071 温州医科大学附属第二医院浙江温州325035 常州市第二人民医院江苏常州213003 汕头大学医学院第一附属医院广东汕头515041 中南大学湘雅二医院长沙410013 云南省第二人民医院昆明650021 盐城市第一人民医院江苏盐城224006 山西省人民医院太原030012 佛山市第一人民医院广东佛山528000 重庆医科大学附属第一医院重庆400016 西安交通大学第一附属医院西安710061 解放军总医院第三医学中心北京100039 深圳市人民医院广东深圳518001 吉林大学第一医院长春130031 山西医学科学院山西大医院太原030032 解放军第254医院天津300142 青岛大学附属医院山东青岛266003 临海市第一人民医院浙江台州317000 华中科技大学同济医学院附属同济医院武汉430030 大连医科大学附属第一医院辽宁大连116011 北京朝阳医院京西院区北京100043 重庆医科大学附属第二医院重庆400016 玉溪市人民医院云南玉溪653405 首都医科大学世纪坛医院北京100036 中南大学湘雅医院长沙410013 深圳市南山人民医院广东深圳518067 内蒙古医科大学附属医院呼和浩特010050 南京明基医院南京210019 首都医科大学附属北京潞河医院北京101149 京煤集团总医院北京102300 江西省人民医院南昌330006 暨南大学附属第一医院广

目的了解国内ICU收治患者的营养治疗实施状况。方法对国内116家医院的118个ICU内的患者进行营养治疗实施状况的横断面调查。以2017年4月26日0时所有在ICU内治疗的患者为调查对象,收集患者基本信息、2017年4月25日(即调查日)的营养实施... 详细信息

目的了解国内ICU收治患者的营养治疗实施状况。方法对国内116家医院的118个ICU内的患者进行营养治疗实施状况的横断面调查。以2017年4月26日0时所有在ICU内治疗的患者为调查对象,收集患者基本信息、2017年4月25日(即调查日)的营养实施和胃肠道耐受情况,以及患者的28 d临床转归情况。结果调查共收集病例1953例,女631例(32.4%),男1306例(66.9%),缺失16例(0.7%);年龄(64.1±19.3)岁(1950例)。患者GCS、SOFA和APACHEⅡ评分分别为(10.76±4.35)分(1749例)、(5.65±3.52)分(1783例)、(17.14±7.31)分(1792例)。28 d临床转归存活1483例(75.9%),死亡312例(16.0%),失访+缺失158例(8.1%)。除身高和体重(P=0.000)外,男性与女性患者在年龄、病情严重程度及28 d临床转归等方面差异均无统计学意义。1953例患者中,胃肠功能评估为正常或轻度损害占73.7%(1440例),中-重度损害占10.8%(210例),衰竭占1.7%(33例),13.2%(258例)的患者未做评估。截至调查日,69.4%(1356例)的患者已启动肠内营养(EN),36.4%(711例)的患者已启动肠外营养(PN)。调查日有营养摄入的患者1720例(88.1%)。1953例患者中明确有恶心、呕吐反流、误吸、腹痛、腹胀、腹泻(大便次数≥3次/d且量≥500 ml/d)等胃肠道不耐受表现的分别占总人数的4.8%(93例)、5.4%(105例)、0.9%(17例)、8.7%(170例)、27.5%(538例)和4.3%(84例)。在1270例使用EN的病例中,明确存在恶心、呕吐反流、误吸、腹痛、腹胀、腹泻等不耐受症状的分别占3.2%(40例)、4.3%(54例)、0.8%(10例)、4.4%(56例)、26.9%(341例)和5.4%(69例)。入ICU后24 h内开始EN治疗的患者占22.4%(437/1953),48 h内开始的占38.6%(754/1953),72 h内开始的占46.6%(911/1953)。患者入ICU后3 d总热卡(EN+PN非蛋白热卡)达标率为12.9%(78/607),7 d总热卡达标率为18.7%(189/1010),14 d总热卡的达标率为23.0%(305/1325)。入ICU后3、7、14 dEN达标率分别为9.9%(60/607)、15.0%(151/1010)和18.6%(246/1325)。结论目前我国ICU内的绝大多数患者均接受了营养治疗,其中EN的使用率明显高于PN;但EN的开始时间和达标情况仍不理想,且实施营养治疗时未能体现个体化差异,营养治疗的细节仍需要提高。

关键词：横断面研究肠内营养重症监护病房胃肠道耐受性营养达标率

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