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Journal of Cancer Therapy 2011年第5期2卷 601-606页

作者： Kenneth J. Hsu Chao S. Huangfu min z. qin 不详

Statistics and experiments indicate a correlation between cancer mortality and nitrite in drinking water. Nitrite is a reductant that can deprive a cell of oxygen;it is also an oxidant that can be a substrate in anaerobic ammonium oxidation, the metabolic mode of the anammox bacteria. Eukaryote cells evolved through a fusion of anaerobic and aerobic bacteria. We postulate that an anammox bacterium sought refuge in a fusion with a membrane-bound cluster of aerobic bacteria. While the latter evolved into mitochondria organelles, the former became the nucleus of a prokaryote cell. Eventually, oxidative phosphorilation is the characteristic metabolic pathway of normal eukaryote cells, and we postulate that anammox is the protein-catabolism pathway for cancer cells. The metabolism consumes nitrite and explains thus the link between nitrite and cancer.

关键词： Nitrite Tomor Symbiogenetic Evolution

Dietary supplementation with N‑acetyl‑L‑cysteine ameliorates hyperactivated ERK signaling in the endometrium that is linked to poor pregnancy outcomes following ovarian stimulation in pigs

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Journal of Animal Science and Biotechnology 2025年第1期16卷 167-181页

作者： Linghua Cheng z.icheng Shi Yuan Yue Yue Wang Yusheng qin Wei z.ao Yupei Hu qin Li min Guo Lei An Shumin Wang Jianhui Tian Frontiers Science Center for Molecular Design Breeding(MOE) State Key Laboratory of Animal Biotech BreedingKey Laboratory of Animal GeneticsBreeding and Reproduction of the Ministry of Agriculture and Rural AffairsNational Engineering Laboratory for Animal BreedingCollege of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193People’s Republic of China

Background Exogenous gonadotropin-controlled ovarian stimulation is the critical step in animal reproductive management,such as pig,sheep,bovine and other *** helps synchroniz. ovulation or stimulate multiple ***,a number of evidence indicated an unexpected decrease in pregnancy outcomes following ovarian *** study aimed to explore the underlying mechanism of the pregnancy defect and develop a practical rescue *** Compared with those in the control group,gilts that underwent ovarian stimulation showed a decrease in pregnancy rate,farrowing rate,and total number of piglets *** gilts also showed an increase in estra-diol(E_(2))*** supraphysiologicalE_(2) level was correlated with the decrease in the number of piglets ***,we found that high levels ofE_(2) impair uterine receptivity,as shown by the overproliferation of endo-metrial epithelial *** vitro mechanistic studies demonstrated that high levels ofE_(2) hyperactivate FGF-FGFR-ERK signaling cascade in the uterine endometrium,and in turn induces overproliferation of endometrial epithelial *** note,N-acetyl-L-cysteine(NAC)supplementation effectively inhibits ERK hyperphosphorylation and ameliorates endometrial epithelial ***,in vivo experiments indicated that dietary NAC supplementa-tion,compared with ovarian stimulation group,improves the uterine receptivity in gilts,and significantly increases the pregnancy rate and total number of piglets *** Ovarian stimulation-induced supraphysiological levels ofE_(2) impairs uterine receptivity by hyperactivat-ing FGF-FGFR-ERK signaling cascade,thereby reducing pregnancy rate and litter *** NAC to a con-ventional diet for gilts ameliorates hyperactivated ERK signaling and improves uterine receptivity,thus rescuing adverse pregnancy outcomes following ovarian stimulation.

关键词： Estradiol Gonadotropin Implantation N-acetyl-L-cysteine Ovarian stimulation Uterine receptivity

Petrogenesis of late Cretaceous high Ba-Sr granodiorites,SE Lhasa block,China:implications for the reworking of juvenile crust and continental growth

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Acta Geochimica 2025年第1期44卷 86-111页

作者： Li-Hang Lin Ren-z.i z.u Shao-Cong Lai Jiang-Feng qin Yu z.u Shao-Wei z.ao min Liu State Key Laboratory of Continental Dynamics Department of GeologyNorthwest UniversityXi’an 710069China ministry of Education Key Laboratory of Western China’s mineral Resources and Geological Engineering School of Earth Science and ResourcesChang’an UniversityXi’an 710054China

The high Ba-Sr rocks can provide significant clues about the evolution of the continent lithosphere,but their petrogenesis remains *** the Late Cretaceous high Ba–Sr granodiorites in the SE Lhasa Block could potentially provide valuable insights into the continent evolution of the qinghai-Tibet *** U–Pb ages suggest that the granodiorites were emplaced at 87.32±0.43 ***,the high Ba–Sr granodiorites are characteriz.d by elevated K_(2)O+Na_(2)O contents(8.18-8.73 wt%)and K_(2)O/Na_(2)O ratios(0.99-1.25,mostly>1),and belong to high-K calc-alkaline to shoshonitic *** Yonglaga granodiorites show notably high Sr(653-783 ppm)and Ba(1346-1531 ppm)contents,plus high Sr/Y(30.92-38.18)and(La/Yb)_(N)(27.7-34.7)ratios,but low Y(20.0-22.8 ppm)and Yb(1.92-2.19 ppm)contents with absence of negative Eu anomalies(δEu=0.83-0.88),all similar to typical high Ba–Sr *** variable z.rconεHf(t)values of-4.58 to+12.97,elevated initial^(87)Sr/^(86)Sr isotopic ratios of 0.707254 to 0.707322 and lowεNd(t)values of-2.8 to-3.6 with decoupling from the Hf system suggest that a metasomatiz.d mantle source included significant recycled ancient *** occurrence of such high Ba–Sr intrusions indicates previous contributions of metasomatiz.d mantle-derived juvenile material to the continents,which imply the growth of continental crust during the Late Cretaceous in the SE *** with regional data,we infer that the underplated mafic magma provides a significant amount of heat,which leads to partial melting of the juvenile *** melting of the metasomatiz.d mantle could produce a juvenile mafic lower crust,from which the high Ba–Sr granitoids were derived from reworking of previous mafic crust during the Late Cretaceous(ca.100-80 Ma)in the SE Lhasa.

关键词： Late Cretaceous High Ba-Sr granodiorites SE Lhasa Growth of continental crust Juvenile crust

Territorial Ecological Restoration with a High-carbon Storage Focus in the Beibu Gulf Urban Agglomeration of China:Insights from Carbon Metabolism Spatial Security Patterns

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Chinese Geographical Science 2025年第1期35卷 73-91页

作者： qin Menglin LIU Yuting TAN Qianxi z.U z.ming WU Xinyu JIANG Hongbo LI Hang SHI Qianqian School of Civil Engineering and Architecture Guangxi UniversityNanning 530004China School of Forestry Guangxi UniversityNanning 530004China Ecosystem Science and Management Program University of Northern British ColumbiaPrince George V2N 4Z9Canada z.uhai Institute of Planning and Design Zhuhai 519000China

This study focuses on urgent research on restoring and enhancing carbon storage capacity in the Beibu Gulf Urban Agglomer-ation of China,a key area in the‘Belt and Road’Initiative,which aligns with carbon peaking and neutrality *** research ana-lyz.s the spatial characteristics of carbon metabolism from 2000 to 2020 and uses models to identify stable carbon sink areas,positive carbon flow corridors,and carbon sequestration *** goal is to construct a carbon metabolism spatial security pattern(CMSSP)and propose territorial ecological restoration strategies under different development demand *** results show the following:1)in 2020,the study area’s carbon sink decreased by 8.29×10^(4) t C/yr compared with that in 2010 and by 10.83×10^(4) t C/yr compared with that in ***-carbon sinks were found mainly in mountainous areas,whereas low-carbon sinks are concentrated in urban con-struction land,rural residential areas,and land margins.2)From 2000 to 2020,the spatial security pattern of carbon metabolism tended to be‘high in the middle of the east and west and low in the gulf.’In 2000,2010,and 2020,16 stable carbon sinks were *** carbon energy flow density in Guangxi was greater than that in Guangdong and Hainan,with positive carbon flow corridors located primarily in Guangxi and *** number of carbon sequestration nodes remained stable at approximately 15,mainly in Guangxi and Hainan.3)Scenario simulations revealed that under the Nature-based mild restoration scenario,the carbon sink rate will reach 611.85×10^(4) t C/yr by 2030 and increase to 612.45×10^(4) t C/yr by 2060,with stable carbon sinks increasing to *** the restora-tion scenario based on Anti-globaliz.tion,the carbon sink will decrease from 610.24×10^(4) t C/yr in 2030 to 605.19×10^(4) t C/yr in 2060,with the disappearance of some positive carbon flow corridors and stable carbon *** the Human-based sustainable restoration scenario,the carbon sink area wil

关键词： carbon metabolism spatial security pattern(CMSSP) territorial ecological restoration carbon sink carbon storage capacity Beibu Gulf Urban Agglomeration,China

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中国儿童青少年遗尿症患病率及影响因素的Meta分析

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中国全科医学 2025年第6期28卷 763-770,776页

作者：刘芹程敏江凤琼李小玉川北医学院护理学院四川省南充市637000 电子科技大学医学院附属绵阳医院绵阳市中心医院四川省绵阳市621000

背景遗尿症是儿科常见疾病之一,近年来,遗尿症对儿童青少年身心健康造成了极大的威胁,严重影响患儿的生活质量,给社会和家庭带来严重的负担。目前,关于儿童青少年遗尿症的影响因素还存在争议,且国内外鲜见相关的系统评价。目的利用Meta... 详细信息

背景遗尿症是儿科常见疾病之一,近年来,遗尿症对儿童青少年身心健康造成了极大的威胁,严重影响患儿的生活质量,给社会和家庭带来严重的负担。目前,关于儿童青少年遗尿症的影响因素还存在争议,且国内外鲜见相关的系统评价。目的利用Meta分析探讨国内儿童青少年遗尿症的患病率和影响因素。方法计算机检索中国知网(CNKI)、万方数据知识服务平台(Wanfang Data)、维普网(VIP)、中国生物医学文献服务系统(SinoMed)、PubMed、Embase、Web of Science、Cochrane Library数据库中的相关研究,检索时间从建库至2024年5月。由2名研究者独立筛选并交叉核对,横断面研究采用美国医疗保健研究与质量机构进行评估,采用Stata17.0软件进行Meta分析。结果共纳入27篇文献,包括243530例患儿。Meta分析结果显示,中国儿童青少年遗尿症患病率为6.1%(95%CI=5.1%~7.2%),其中,男性(OR=1.52,95%CI=1.41~1.64)、遗尿症家族史(OR=3.46,95%CI=2.01~5.93)、便秘(OR=2.32,95%CI=1.59~3.40)、尿路感染史(OR=2.33,95%CI=1.81~3.01)、睡眠障碍(OR=2.01,95%CI=1.10~3.67)、尿频(OR=1.90,95%CI=1.43~2.52)、尿急(OR=1.67,95%CI=1.31~2.12)、尿失禁(OR=4.85,95%CI=2.78~8.45)是儿童青少年遗尿症的危险因素(P<0.05);排尿训练(OR=0.11,95%CI=0.02~0.46)是儿童青少年遗尿症的保护因素(P<0.05)。结论中国儿童青少年遗尿症患病率较高,性别、遗尿症家族史、便秘、尿路感染史、排尿训练、睡眠障碍、尿频、尿急、尿失禁是儿童青少年遗尿症的主要影响因素。因此,未来应对儿童青少年遗尿症进行早期识别和干预,提高家长对遗尿症的重视,做好疾病宣教普及,减少遗尿症患病率,提高患儿及家庭生活质量。

关键词：遗尿遗尿症儿童青少年患病率影响因素 Meta分析

Effects of diurnal adjustment on biases and trends derived from inter-sensor calibrated AMSU-A data

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Frontiers of Earth Science 2018年第1期12卷 1-16页

作者： H. CHEN X. z.U z. qin Department of Atmospheric and Oceanic Sciences University of Colorado Boulder Colorado CO 80309 USA Earth System Science Interdisciplinary Center (ESSIC) University of Maryland College Park Maryland MD 20742 USA Joint Center for Data Assimilation Research and Applications Nanjing University of Information Science and Technology Nanjing 210044 China

Measurements of brightness temperatures from Advanced Microwave Sounding Unit-A （AMSU-A） temperature sounding instruments onboard NOAA Polar- orbiting Operational Environmental Satellites （POES） have been extensively used for studying atmospheric temperature trends over the past several decades. Inter- sensor biases, orbital drifts and diurnal variations of atmospheric and surface temperatures must be considered before using a merged long-term time series of AMSU-A measurements from NOAA- 15, - 18, - 19 and MetOp-A. We study the impacts of the orbital drift and orbital differences of local equator crossing times （LECTs） on temperature trends derivable from AMSU-A using near-nadir observa- tions from NOAA-15, NOAA-18, NOAA-19, and MetOp-A during 1998 - 2014 over the Amaz.n rainforest. The double difference method is firstly applied to estimation of inter-sensor biases between any two satellites during their overlapping time period. The inter-calibrated observations are then used to generate a monthly mean diurnal cycle of brightness temperature for each AMSU-A channel. A diurnal correction is finally applied each channel to obtain AMSU-A data valid at the same local time. Impacts of the inter-sensor bias correction and diurnal correction on the AMSU-A derived long-term atmospheric temperature trends are separately quantified and compared with those derived from original data. It is shown that the orbital drift and differences of LECT among different POESs induce a large uncertainty in AMSU-A derived long-term warming/cooling trends. After applying an inter-sensor bias correction and a diurnal correction, the warming trends at different local times, which are approximately the same, are smaller by half than the trends derived without applying these corrections.

关键词： AMSU-A diurnal adjustment decadal tem-perature trend

智能时代的红树林知识服务展望:从植物图谱到知识图谱

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中国科学:地球科学 2025年第1期55卷 111-125页

作者：侯志伟荆文龙秦承志杨骥夏清尹小玲广东省科学院广州地理研究所广东省遥感与地理信息系统应用重点实验室广东省地理时空大数据工程实验室广州510070 南方海洋科学与工程广东省实验室(广州) 广州511458 中国科学院地理科学与资源研究所资源与环境信息系统国家重点实验室北京100101 中国科学院大学资源与环境学院北京100049 长沙理工大学交通运输工程学院长沙410114

红树林关乎地球生态安全和人类福祉,其管理、保护与修复离不开生物、生态等多学科领域知识与时空信息的支撑.植物图谱等传统知识服务可以提供图文并茂的红树林知识.然而,这种面向信息检索的服务方式,无法有效挖掘和利用多源异构数据中... 详细信息

红树林关乎地球生态安全和人类福祉,其管理、保护与修复离不开生物、生态等多学科领域知识与时空信息的支撑.植物图谱等传统知识服务可以提供图文并茂的红树林知识.然而,这种面向信息检索的服务方式,无法有效挖掘和利用多源异构数据中的碎片化知识,面临“数据海量、知识难求”困境.知识图谱可将海量数据中蕴含的知识,提取、组织、融合为计算机可理解、可计算的语义网络,为实现智能知识服务提供了解决方案.本文聚焦红树林知识获取、形式化表达及智能服务的迫切需求,提出了红树林知识图谱和知识服务构想.首先分析了不同领域图谱概念的异同,认为红树林知识图谱是以红树林生态系统为核心,融合了多领域知识和时空信息的大规模知识库;然后提出了红树林知识服务的研究框架,该框架可实现多模态数据到智能知识服务的转变,包括泛在数据感知与汇聚、知识组织与图谱构建、智能知识服务等多个层次;接着重点介绍了红树林知识图谱的构建方法与流程;最后探讨了目前红树林知识服务面临的挑战,提出在人工智能时代,构建融合领域特色与时空特征的红树林知识体系,探索大模型支持下的知识抽取与融合方法,并研发面向典型场景的智能知识应用,是红树林知识服务的主要发展方向.

关键词：红树林图谱知识图谱多模态知识服务

Dimer of Bis[trans-5-methyl-2-[2-(4-methoxylphenyl)ethenyl]-benz.xaz.le]di-μ-nitratosilver(I)

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Chinese Journal of Structural Chemistry 2004年第5期23卷 532-536页

作者： LIUHui-min z.ANGWei XINYing z.ANGWen-qin （DepartmentofChemistry TianjinUniversityTianjin300072China

The title complex [AgNO3(C17H15NO2)2]2 was synthesiz.d and characteriz.d by X-ray diffraction analysis. The compound crystalliz.s in triclinic, space group P with a = 11.226(7), b = 11.906(7), c = 12.144(7) , = 99.796(10), = 91.631(10), = 101.225(10), V = 1565.6(16) 3, z.= 1, Mr = 1400.96, Dc = 1.486 g/cm3, F(000) = 716 and (Mo-K? = 0.697 mm-1. The final R and wR are 0.0401 and 0.0995, respectively for 5492 independent observable reflections with I > 2(I). The results show that the central Ag atom is four-coordinated with two O atoms from two distinct NO3- anions and two N atoms from two trans-5-methyl-2-[2-(4-methoxylphenyl)ethenyl]- benz.xaz.le ligands, and the two Ag atoms bridged with two O atoms give an interesting Ag-O-Ag-O parallelogram structure. The coordination sphere of Ag atom exhibits a heavily distorted tetrahedral geometry and the coordination angles lie in the range of 66.73(12)～129.59(10). The intra- molecular dihedral angles between the benz.xaz.lyl and phenyl planes are 4.1(3) and 2.9(3), respectively.

关键词： synthesis crystal structure trans-2-styrylbenz.xaz.le silver complex

Properties of polyferric-silicate-sulfate(PFSS) coagulant

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Journal of Environmental Sciences 2000年第2期12卷 107-110页

作者： Bao-yu, G. qin-yan, Y. Hua-z.ang, z. Yong-hui, S. Dept. of Environmental Engineering Shandong University Jinan 250100 China

Polyferric\|silicate\|sulfate(PFSS),as a new type of coagulant,was prepared by using sodium silicate, sulfuric acid and ferric sulfate as *** z.ta potential of hydrolyz.te of PFSS under different pH values was *** effects of Fe/SiO\-2 molar ratio and dosage of PFSS on turbidity removal were studied. The relation between the optimum coagulation pH range and Fe/SiO\-2 molar ratio was found and the coagulation mechanism of PFSS was *** experimental results showed that Fe/SiO\-2 molar ratio has an effect on the z.ta potential of hydrolyz.te, the coagulation performance and the optimum coagulation pH range of PFSS and that PFSS gives the best turbidity removal effect when its Fe/SiO\-2 molar ratio was 1.5.

关键词： inorganic polymer coagulant polyferric\|silicate\|sulfate polymeriz.tion of silicic acid z.ta potential turbidity removal CLC number: X703 Document code: A

Whole-infrared-band camouflage with dual-band radiative heat dissipation

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Light(Science & Applications) 2023年第11期12卷 2391-2401页

作者： Bing qin Yining z.u Yiwei z.ou min Qiu Qiang Li State Key Laboratory of Modern Optical Instrumentation College of Optical Science and EngineeringZhejiang UniversityHangzhou 310027China Key Laboratory of 3D Micro/Nano Fabrication and Characteriz.tion of z.ejiang Province School of EngineeringWestlake University18 Shilongshan RoadHangzhou 310024 ZhejiangChina Institute of Advanced Technology Westlake Institute for Advanced Study18 Shilongshan RoadHangzhou 310024 ZhejiangChina

Advanced multispectral detection technologies have emerged as a significant threat to objects,necessitating the use of multiband ***,achieving effective camouflage and thermal management across the entire infrared spectrum,especially the short-wave infrared(SWIR)band,remains *** paper proposes a multilayer wavelength-selective emitter that achieves effective camouflage across the entire infrared spectrum,including the near-infrared(NIR),SWIR,mid-wave infrared(MWIR),and long-wave infrared(LWIR)bands,as well as the visible(VIS)***,the emitter enables radiative heat dissipation in two non-atmospheric windows(2.5-3μm and 5-8μm).The emitter’s properties are characteriz.d by low emittance of 0.270/0.042/0.218 in the SWIR/MWIR/LWIR bands,and low reflectance of 0.129/0.281 in the VIS/NIR ***,the high emittance of 0.742/0.473 in the two non-atmospheric windows ensures efficient radiative heat dissipation,which results in a temperature decrement of 14.4℃ compared to the Cr reference at 2000Wm^(−2) input power *** work highlights the role of solar radiance in camouflage,and provides a comprehensive guideline for developing multiband camouflage compatible with radiative heat dissipation,from the visible to LWIR.

关键词： dissipation visible radiative