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Petroleum Science 2024年第3期21卷 1474-1487页

作者： Shu-Heng Du Yong-min Shi State Key Laboratory of Nonlinear Mechanics Institute of MechanicsChinese Academy of SciencesBeijing100190China School of Engineering Science University of Chinese Academy of SciencesBeijing100049China School of Earth and Space Sciences Peking UniversityBeijing100871China

In this study,a new image-based method for the extraction and characterization of pore-throat network for unconventional hydrocarbon storage and exploitation is proposed.“Pore-throat solidity”,which is analogous to particle solidity,and a new method for automatic identification of pores and throats in tight sandstone oil reservoirs are ***,the“pore-throat combination”and“pure pore”are defined and distinguished by drawing the cumulative probability curve of the pore-throat solidity and by selecting an appropriate cutoff *** the discrete grid set is recognized as a pore-throat combination,Legendre ellipse fitting and minimum Feret diameter are *** the pore and throat grid sets are identified as pure pores,the pore diameter can be directly *** the new method,the analytical results for the physical parameters and pore radius agree well with most prior *** results comparing the maximum ball and the new model could also prove the accuracy of the latter's in micro and nano *** new model provides a more practical theoretical basis and a new calculation method for the rapid and accurate evaluation of the complex processes of oil migration.

关键词： Hydrocarbon exploitation Pore Throat Porous media Identification

Allelic reprogramming of chromatin states in human early embryos

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National Science Review 2024年第03期11卷 58-71页

作者： Shenli Yuan Lei Gao Wenrong Tao Jianhong Zhan Gang Lu Jingye Zhang Chuanxin Zhang Lizhi Yi Zhenbo Liu Zhenzhen Hou min Dai Han Zhao Zi-Jiang Chen Jiang Liu Keliang Wu Center for Reproductive Medicine Shandong University CAS Key Laboratory of Genome Sciences and Information Collaborative Innovation Center of Genetics and Development Beijing Institute of Genomicsand China National Center for BioinformationChinese Academy of Sciences University of Chinese Academy of Sciences CUHK-SDU Joint Laboratory on Reproductive Genetics School of Biomedical Sciences the Chinese University of Hong Kong Key Laboratory of Reproductive Endocrinology of the ministry of Education Shandong University Center for Reproductive Medicine Ren Ji Hospital School of Medicine Shanghai Jiao Tong University CAS Center for Excellence in Animal Evolution and Genetics Chinese Academy of Sciences

The reprogramming of parental epigenomes in human early embryos remains elusive. To what extent the characteristics of parental epigenomes are conserved between humans and mice is currently unknown. Here,we mapped parental haploid epigenomes using human parthenogenetic and androgenetic embryos. Human embryos have a larger portion of genome with parentally specific epigenetic states than mouse *** allelic patterns of epigenetic states for orthologous regions are not conserved between humans and mice. Nevertheless, it is conserved that maternal DNA methylation and paternal H3K27me3 are associated with the repression of two alleles in humans and mice. In addition, for DNA-methylation-dependent imprinting, we report 19 novel imprinted genes and their associated germline differentially methylated regions. Unlike in mice, H3K27me3-dependent imprinting is not observed in human early ***, allele-specific epigenomic reprogramming is different in humans and mice.

关键词： human embryo epigenetics reprogramming DNA methylation H3K27me3 chromatin accessibility

溯源而治:论工伤认定民行交织争议的实质性解决

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法学家 2024年第5期 72-84,192,193页

作者：王敏厦门大学法学院

工伤认定案件是我国行政诉讼的一个主要类型。实践中,这类案件存在大面积“程序空转”、案结难以事了的现象,阻碍了工伤保险制度功能的发挥。既有的实质性争议解决方案局限于对司法救济方式的改进,忽视了纠纷产生的制度原因,无法从源头... 详细信息

工伤认定案件是我国行政诉讼的一个主要类型。实践中,这类案件存在大面积“程序空转”、案结难以事了的现象,阻碍了工伤保险制度功能的发挥。既有的实质性争议解决方案局限于对司法救济方式的改进,忽视了纠纷产生的制度原因,无法从源头上摆脱困境。比较不同的工伤风险保障模式会发现,我国现行工伤保险制度公私界限模糊,程序碎片化,缺乏对给付权利的有效保障。改进工伤保险制度,以工伤保险给付决定替代现有制度中劳动关系确认、工伤认定、工伤保险待遇认定、待遇给付等繁冗程序,将在源头上化解争议民行交织的现象、减少争议数量,并将激活行政诉讼制度中给付判决解决争议、保障权利、推动给付行政的制度潜能。这一争议解决出路的探讨也展示了行政争议实质性解决的新路径。行政争议是特定制度的产物,关注实体法律制度设计对行政争议解决的影响,才是法治化的“诉源治理”。

关键词：工伤认定社会保险给付行政行政诉讼实质性解决争议

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行政协议之诉赔偿与补偿情形认定

政法论丛 2024年第5期 172-184页

作者：张敏山东政法学院法学院山东济南250014

行政协议之诉赔偿、补偿有其自身的特殊性,既有别于行政赔偿、行政补偿,也不属于民事赔偿、民事补偿,当前理论界有争议,实务中法官可以依法作出不同的裁判。判断行政机关在行政协议之诉中承担赔偿责任还是补偿责任,原则上应为合法优先... 详细信息

行政协议之诉赔偿、补偿有其自身的特殊性,既有别于行政赔偿、行政补偿,也不属于民事赔偿、民事补偿,当前理论界有争议,实务中法官可以依法作出不同的裁判。判断行政机关在行政协议之诉中承担赔偿责任还是补偿责任,原则上应为合法优先、兼顾公益,合法行为造成的损失予以补偿,违法行为造成的损失予以赔偿,但为了公共利益需要且仅是程序违法的情况下,可以只给予补偿。行政协议之诉赔偿、补偿应尽可能明确具体标准,不能明确的,应比照行政赔偿适当增加,而且赔偿应高于补偿。对行政协议纠纷作出裁判应优先适用行政法律规范,即便需要参照适用民事法律规范,也需要考量能否有效维护社会公共利益,不能随意参照适用。

关键词：行政协议赔偿补偿合法优先兼顾公益参照适用

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论明清《衢州府志》的秩序意识

浙江社会科学 2024年第10期 137-145,F0003页

作者：汤敏浙江省社会科学院杭州310007

秩序意识是中国人深沉的文化心理。地方志以纲张目举的形式网罗故实,囊括大典。其穷搜博采、勾陈稽考之处实有着复杂的动因与考量。浙江衢州是“东南阙里”“南孔圣地”。衢州历代府志在深植儒家意识上颇具代表性。四部明清《衢州府志... 详细信息

秩序意识是中国人深沉的文化心理。地方志以纲张目举的形式网罗故实,囊括大典。其穷搜博采、勾陈稽考之处实有着复杂的动因与考量。浙江衢州是“东南阙里”“南孔圣地”。衢州历代府志在深植儒家意识上颇具代表性。四部明清《衢州府志》皆有鲜明的秩序意识导向。它们既标举理想的社会秩序,也如实记载了影响秩序稳定的变量因素,从而凸显了形塑与维护秩序的必要性与重要性,也体现了地方志这一文体在凝聚地方社会、植入共同秩序意识上所发挥的独特作用。讨论地方志编纂的秩序意识,无论在方法论层面还是价值追求上都对当代修志具有启示性意义,亦可为和谐社会建设提供鲜活的历史记忆与切实的行动指南。

关键词：秩序意识《衢州府志》儒家精神礼乐教化

The low Mach number limit of non-isentropic magnetohydrodynamic equations with large temperature variations in bounded domains

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Science China Mathematics 2024年第4期67卷 787-818页

作者： min Liang Yaobin Ou School of Mathematics Renmin University of ChinaBeijing 100872China

This paper verifies the low Mach number limit of the non-isentropic compressible magnetohydrodynamic(MHD)equations with or without the magnetic diffusion in a three-dimensional bounded domain when the temperature variation is large but *** uniform estimates of strong solutions are established in a short time interval independent of the Mach number,provided that the slip boundary condition for the velocity and the Neumann boundary condition for the temperature are imposed and the initial data is well-prepared.

关键词： low Mach number limit non-isentropic compressible magnetohydrodynamic equations large temperature variations bounded domains

Phase-Field Simulation of Sintering Process:A Review

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1165-1204页

作者： ming Xue min Yi State Key Laboratory ofMechanics and Control forAerospace Structures&Institute for Frontier Science&Key Laboratory for Intelligent Nano Materials and Devices of ministry of Education&College of Aerospace Engineering Nanjing University of Aeronautics and Astronautics(NUAA)Nanjing210016China

Sintering,a well-established technique in powder metallurgy,plays a critical role in the processing of high melting point materials.A comprehensive understanding of structural changes during the sintering process is essential for effective product *** phase-field method stands out for its unique ability to simulate these structural *** its widespread application,there is a notable absence of literature reviews focused on its usage in sintering ***,this paper addresses this gap by reviewing the latest advancements in phase-field sintering models,covering approaches based on energy,grand potential,and entropy *** characteristics of various models are extensively discussed,with a specific emphasis on energy-based models incorporating considerations such as interface energy anisotropy,tensor-form diffusion mechanisms,and various forms of rigid particle motion during ***,the paper offers a concise summary of phase-field sintering models that integrate with other physical fields,including stress/strain fields,viscous flow,temperature field,and external electric *** conclusion,the paper provides a succinct overview of the entire content and delineates potential avenues for future research.

关键词： Phase-field model review sintering additive manufacturing

记录者与梦想家——重勘《曼哈顿的中国女人》的通俗张力

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小说评论 2024年第4期 109-114页

作者：王敏浙江外国语学院

在中国当代文学史涌现的诸多现象级文本中,《曼哈顿的中国女人》曾是极富争议的作品之一,这些争议既来自文学批评视野之内,又溢出其外,构成了喧闹一时的现象之一隅,也生动阐释了现象级文本可能对文学边界造成的冲击,以及随之而来的风格... 详细信息

在中国当代文学史涌现的诸多现象级文本中,《曼哈顿的中国女人》曾是极富争议的作品之一,这些争议既来自文学批评视野之内,又溢出其外,构成了喧闹一时的现象之一隅,也生动阐释了现象级文本可能对文学边界造成的冲击,以及随之而来的风格特征的复杂与多变。

关键词：中国当代文学史文学边界批评视野梦想家《曼哈顿的中国女人》风格特征争议

Real-time in-situ monitoring of chiral changes during a reaction at single-molecule level

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Science China Chemistry 2024年第2期67卷 422-423页

作者： min Tan Dong Xiang Institute of Modern Optics and Center of Single-Molecule Science Tianjin Key Laboratory of Micro-scale Optical Information Science and TechnologyNankai UniversityTianjin300350China School of Materials Science and Engineering Smart Sensing Interdisciplinary Science CenterNankai UniversityTianjin300350China TongLu FeiRan Garment–Nankai University Joint Laboratory Nankai UniversityTianjin300350China

Molecular chirality is a widespread phenomenon in nature,playing a critical role in various fields such as chemistry [1],life sciences [2], and materials science [3], and has therefore attracted significant attention and research by scholars [4–6].However, the chirality in chemical reactions is often dynamic, making real-time monitoring of chiral changes during chemical reactions at the single-molecule level extremely challenging.

关键词： chiral chirality critical

Transformation of marginal zone lymphoma into high-grade B-cell lymphoma expressing terminal deoxynucleotidyl transferase:A case report

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World Journal of Clinical Cases 2024年第15期12卷 2655-2663页

作者： Zhi-min Fan Dao-Lei Wu Neng-Wen Xu Li Ye Li-Ping Yan Lin-Jie Li Jun-Yu Zhang Department of Hematology Lishui Municipal Central HospitalLishui 323000Zhejiang ProvinceChina Department of Ophthalmology Lishui Municipal Central HospitalLishui 323000Zhejiang ProvinceChina Department of General Practice Lishui Municipal Central HospitalLishui 323000Zhejiang ProvinceChina Department of Pathology Lishui Municipal Central HospitalLishui 323000Zhejiang ProvinceChina

BACKGROUND High-grade B-cell lymphoma(HGBL)is an unusual malignancy that includes myelocytomatosis viral oncogene(MYC),B-cell lymphoma-2(BCL-2),and/or BCL-6 rearrangements,termed double-hit or triple-hit lymphomas,and HGBL-not otherwise specific(HGBL-NOS),which are morphologically characteristic of HGBL but lack MYC,BCL-2,or BCL-6 *** is partially transformed by follicular lymphoma and other indolent lymphoma,with few cases of marginal zone lymphoma(MZL)*** often has a poor prognosis and intensive therapy is currently mainly advocated,but there is no good treatment for these patients who cannot tolerate *** SUMMARY We reported a case of MZL transformed into HGBL-NOS with TP53 mutation and terminal deoxynucleotidyl transferase *** analysis revealed the gene expression profile was identical in the pre-and post-transformed tissues,suggesting that the two diseases are homologous,not secondary *** chemotherapy was ineffective and the side effect was severe,so we tried combination therapy including venetoclax and *** patient tolerated treatment well,and reached partial *** patient had recurrence of hepatocellular carcinoma and died of multifunctional organ *** survived for 12 months after *** Venetoclax combined with obinutuzumab might improve the survival in some HGBL patients,who are unsuitable for chemotherapy.

关键词： Marginal zone lymphoma High-grade B-cell lymphoma Terminal deoxynucleotidyl transferase Venetoclax TP53 mutation Case report