检索结果-南通市图书馆

T cell responses to hepatitis B surface antigen are detectable in non-vaccinated individuals

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2008年第16期14卷 2529-2533页

作者： Martin R Weihrauch Michael von Bergwelt-Baildon milos Kandic Martin Weskott Winfried Klamp Joachim Rsler Joachim L Schultze Molecular Tumor Biology and Tumor Immunology University of Cologne Gesundheitsschutz Wuppertaler Stadtwerke AG Department for Occupational Health University of Cologne

AIM: To evaluate, whether humoral hepatitis-B-vaccine non-responders also fail to mount a T cell response and to compare these results to normal vaccinees. METHODS: Fourty-seven health care employees were enrolled in this study including all available non- responders (n = 13) with an anti-HBsAg titer 1000 kU/L as controls. PBMC from all subjects were analyzed by IFN-γ and IL-4 ELISPOT assays for the presence of hepatitis B surface antigen (HBsAg) reactive T cells. RESULTS: Non-responders and low-responders had no or only very limited T cell responses, respectively. Indi- viduals responding to vaccination with the induction of a high anti-HBsAg titer showed a strong T cell response after the third vaccination. Surprisingly, these individuals showed response even before the first vaccination. T cell response to control antigens and mitogens was similar in all groups. CONCLUSION: Our data suggest that there is no gen- eral immune deficiency in non-/low-responders. Thus, we hypothesize that the induction of anti-HBsAg re- sponses by vaccination is significantly dependent on the pre-existing T cell repertoire against the specific antigen rather than the presence of a general T cell defect.

关键词：乙肝 T细胞疫苗接种症状

Photoperiodic effects on urinary attractiveness and volatile composition of the house mouse （Mus musculus）

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photoperiodic effects on urinary attractiveness and volatile...

中国动物学会兽类学分会第六届会员代表大会暨学术讨论会

作者： Helena A. Soini Kevin E. Bruce Donald Weisler milos V. Novotny institute for Pheromone Research and Department of Chemistry Indiana University Bloomington IN 47405 USA institute for Pheromone Research and Department of Chemistry Indiana University Bloomington IN 47405 USA institute for Pheromone Research and Department of Chemistry Indiana University Bloomington IN 47405 USA institute for Pheromone Research and Department of Chemistry Indiana University Bloomington IN 47405 USA

＜正＞ICR house mice （Mus musculus）, characterized as non-photoperiodic, were housed in short-photoperiod （8 hr. light/day）（SL） and in long-photoperiod （16 hr. light/day）（LL） for one month, respectively. We...

关键词：

Effects of adrenalectomy on dominance-related pheromones in the urine of male house mouse （Mus musculus）

在线全文

cnki会议

学校读者我要写书评

暂无评论

Effects of adrenalectomy on dominance-related pheromones in ...

中国动物学会兽类学分会第六届会员代表大会暨学术讨论会

作者： Helena A. Soini Kevin E. Bruce Donald Weisler milos V. Novotny stitute for Pheromone Research and Department of Chemistry Indiana University Bloomington IN 47405 USA stitute for Pheromone Research and Department of Chemistry Indiana University Bloomington IN 47405 USA stitute for Pheromone Research and Department of Chemistry Indiana University Bloomington IN 47405 USA stitute for Pheromone Research and Department of Chemistry Indiana University Bloomington IN 47405 USA

＜正＞Chemical investigation （GC-MS） and behavioral tests of urine odor of adrenalectomized and sham-adrenalectomized male mice were conducted in this paper. Our results indicated although adrenalectomy could change the urinary volatile composition, it did not change the dominance-related pheromones (E,E-α-farnesene and

关键词：

在线全文

cnki会议

学校读者我要写书评

暂无评论

家庭中磷化氢中毒的案例研究-诊断的困难

家庭中磷化氢中毒的案例研究-诊断的困难

第十五届国际法庭科学大会

作者： Radenko Vukovic milos Tasic Milan Simic Goran Stojiljkovic Dragan Draskovic Djura Vujic 杨士云 University of Novi sad School of MedicineDepartment of Forensic MedicineHajduk Veljkov a 321000 Novi SadFR Yugoslavia University of Novi sad School of MedicineDepartment of Forensic MedicineHajduk Veljkov a 321000 Novi SadFR Yugoslavia University of Novi sad School of MedicineDepartment of Forensic MedicineHajduk Veljkov a 321000 Novi SadFR Yugoslavia University of Novi sad School of MedicineDepartment of Forensic MedicineHajduk Veljkov a 321000 Novi SadFR Yugoslavia University of Novi sad School of MedicineDepartment of Forensic MedicineHajduk Veljkov a 321000 Novi SadFR Yugoslavia University of Novi sad School of MedicineDepartment of Forensic MedicineHajduk Veljkov a 321000 Novi SadFR Yugoslavia

＜正＞参加完这个会议,代表们将能够理解在生活中使用磷化物的后果和在正确检测中毒原因中的困难。这篇文章有两个目的：一是解释一起磷化氢导致全家中毒的特殊案例,二是阐述磷化氢中毒的临床症状和解剖所见。

关键词：毒物学中毒磷化氢

用阶梯状掺杂埋层对超浅结进行C-V剖面分析(英文)

在线全文

cnki会议

学校读者我要写书评

暂无评论

半导体技术 2010年第1期35卷 39-42,89页

作者：徐翠芹 Popadic milos Nanver L.K. 茹国平复旦大学微电子系专用集成电路与系统国家重点实验室上海200433 代尔夫特工业大学ECTM/DIMES实验室荷兰代尔夫特2600

研究了应用双边C-V法测量超浅结(如p+-n结)的掺杂分布。推导了在已知p+-n结的电容-电压(C-VR)关系、n区掺杂、以及热平衡下n区耗尽层宽度(xn0)的情况下计算p区掺杂浓度分布的公式。xn0是计算p区掺杂分布所需的一个关键参数,通过将n区掺... 详细信息

研究了应用双边C-V法测量超浅结(如p+-n结)的掺杂分布。推导了在已知p+-n结的电容-电压(C-VR)关系、n区掺杂、以及热平衡下n区耗尽层宽度(xn0)的情况下计算p区掺杂浓度分布的公式。xn0是计算p区掺杂分布所需的一个关键参数,通过将n区掺杂设计成阶梯状,可实现对xn0的精确提取。用Medici对具有相同的阶梯状掺杂n区的p+-n和n-肖特基结进行器件仿真可得其C-VR关系。运用常规C-V法,由肖特基结的C-VR关系可提取出n区掺杂浓度。实现了对xn0的精确提取,其精度达1.8nm。基于精确的xn0,运用双边C-V法提取的p+区的掺杂浓度分布与Medici仿真结果非常吻合。

关键词：双边结电容-电压超浅结

个人计算机上用的专家系统:TK!Solver法

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

微电子学与计算机 1988年第4期 42-47页

作者： milos Konopasek and Sundaresan Jayaraman 莫梧生

人工智能和微型计算机技术领城的进展已达到在便宜的个人计算机中较易地实现人工智能的某些概念.在问题求解和决策过程中,使个人计算机成为更富智能的一种专家系统软件包的实例就是TKlSolver(工具包!求解器).除了因其本身的质量而成为... 详细信息

人工智能和微型计算机技术领城的进展已达到在便宜的个人计算机中较易地实现人工智能的某些概念.在问题求解和决策过程中,使个人计算机成为更富智能的一种专家系统软件包的实例就是TKlSolver(工具包!求解器).除了因其本身的质量而成为一个专家系统外,TK!Solver还可被非计算机专业以及非人工智能专业的人员用来作为籍各专业中以数量表示的知识库来研制个人化专家系统的框架.

关键词： TK!Solver 变量表专家知识库专家系统人工智能规则表领域个人计算机 PC机

Intraoperative endoscopy in obstructive hypopharyngeal carcinoma

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第28期12卷 4561-4564页

作者： Predrag Pesko milos Bjelovic Predrag Sabljak Dejan Stojakov Ebrahimi Keramatollah Dejan Velickovic Bratislav Spica Branka Nenadic Aleksandra Djuric-Stefanovic Djordjije Saranovic Vera Todorovic Department of Esophagogastric Surgery First Surgical University HospitalClinical Center of SerbiaBelgradeSerbia and Montenegro Institute of Anesthesiology First Surgical University HospitalClinical Center of SerbiaBelgradeSerbia and Montenegro Department of Radiology First Surgical University HospitalClinical Center of SerbiaBelgradeSerbia and Montenegro Institute of Medical Investigations BelgradeSerbia and Montenegro

瞄准：与妨碍的低亚硫酸钠在病人在上面的消化道的第二等的原发性瘤的诊断表明 intraoperative 内视镜检查法的必要性咽头的癌。方法：有低亚硫酸钠的 31 个病人咽头的有鳞的房间癌被操作了与激进的目的，在我们在在 1978 和 2004 之间... 详细信息

瞄准：与妨碍的低亚硫酸钠在病人在上面的消化道的第二等的原发性瘤的诊断表明 intraoperative 内视镜检查法的必要性咽头的癌。方法：有低亚硫酸钠的 31 个病人咽头的有鳞的房间癌被操作了与激进的目的，在我们在在 1978 和 2004 之间的时期的机构。由于妨碍的肿瘤集中，在 7 (22.6%) 病人，食管和胃的外科手术前的内视镜的评估不能被执行。在那些病人， intraoperative 内视镜检查法，在颈的食管通过一个切口做了，是为食管和胃的检查的标准诊断方法。结果：我们在 3 个病人(9.7%) 发现了同步前肠癌。在二个病人，同步的癌在外科手术前的内视镜的评估期间被检测了，并且在一个(与妨碍的癌) 用 intraoperative 内视镜检查法。在这种情况中，，外科手术前的钡燕子和 CT 扫描没在食管以内揭示第二个原发性瘤的存在小，但是 T2 癌，是在场的。结论：与妨碍的低亚硫酸钠把 intraoperative 内视镜检查法用作病人的选择屏蔽测试是合理的咽头的癌。

关键词：手术治疗内窥镜下咽骨癌鳞状细胞

Role of cystatin C and renal resistive index in assessment of renal function in patients with liver cirrhosis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第21期20卷 6573-6579页

作者： Dorde Culafi milos tuli Radmila Obrenovi Danijela Mileti Dragana Mija Milica Stojkovi Marija Jovanovi Milica Culafi Clinic of Gastroenterology and Hepatology Clinical Center of Serbia and School of Medicine University of Belgrade Institute of Medical Biochemistry Clinical Center of Serbia Department of Pharmacoki-netics and Clinical Pharmacy Faculty of Pharmacy University of Belgrade

AIM:To evaluate the clinical significance of cystatin C and renal resistive index for the determination of renal function in patients with liver ***:We conducted a study of 63 patients with liver cirrhosis.A control group comprised of 30 age and gender-matched healthy *** cystatin C was determined in all study subjects and renal Doppler ultrasonography was *** glomerular filtration rate from serum creatinine(GFRCr)and cystatin C(GFRCys)was ***:We confirmed significant differences in val-ues of cystatin C between patients with different stages of liver cirrhosis according to Child-Pugh(P=0.01),and a significant correlation with model of end stage liver disease(MELD)score(rs=0.527,P<0.001).More patients with decreased glomerular filtration rate were identified based on GFRCys than on GFRCr(P<0.001).Significantly higher renal resistive index was noted in Child-Pugh C than in A(P<0.001)and B stage(P=0.001).Also,a significant correlation between renal resistive index and MELD score was observed(rs=0.607,P<0.001).Renal resistive index correlated significantly with cystatin C(rs=0.283,P=0.028)and showed a negative correlation with GFRCys(rs=-0.31,P=0.016).CONCLUSION:Cystatin C may be a more reliable marker for assessment of liver ***,cystatin C and renal resistive index represent sensitive indicators of renal dysfunction in patients with liver cirrhosis.

关键词： Liver cirrhosis Cystatin C Renal resistive index

Individual and Gender Information from Ferret: A Chemical Investigation of Urine in Comparison with Anal Gland Secretion

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Individual and Gender Information from Ferret: A Chemical In...

中国动物学会兽类学分会第六届会员代表大会暨学术讨论会

作者： Helena Soini Kevin Bruce Donald Weisler Sarah K. Woodley Micheal J. Baum milos Novotny titute for Pheromone Research at Department of Chemistry Indiana University Bloomington IN 47405 nstitute of Zoology Chinese Academy of Sciences Beijing 100080 China titute for Pheromone Research at Department of Chemistry Indiana University Bloomington IN 47405 nstitute of Zoology Chinese Academy of Sciences Beijing 100080 China titute for Pheromone Research at Department of Chemistry Indiana University Bloomington IN 47405 nstitute of Zoology Chinese Academy of Sciences Beijing 100080 China Department of Biology Boston University Boston MA 02215 USA titute for Pheromone Research at Department of Chemistry Indiana University Bloomington IN 47405 titute for Pheromone Research at Department of Chemistry Indiana University Bloomington IN 47405

＜正＞In this study, the novel quantitative stir bar sorptive extraction （SBSE） and thermal desorption gas chromatography-mass spectrometry （GC-MS） method was used to investigate urinary volatiles in comparison wi...

关键词：