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Photonic devices fabricated from (111)-oriented single crystal diamond

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InfoMat 2020年第6期2卷 1241-1246页

作者： Blake Regan Sejeong Kim Anh T.H.Ly Aleksandra Trycz Kerem Bray Kumaravelu Ganesan milos toth Igor Aharonovich School of Mathematical and Physical Sciences University of Technology SydneyUltimoNew South WalesAustralia School of Physics University of MelbourneMelbourneVictoriaAustralia

Diamond is a material of choice in the pursuit of integrated quantum photonic *** far,the majority of photonic devices fabricated from diamond are made from(100)-oriented *** this work,we demonstrate a methodology for the fabrication of optically active membranes from(111)-oriented *** use a liftoff technique to generate membranes,followed by chemical vapor deposition of diamond in the presence of silicon to generate homogenous silicon vacancy color centers with emission properties that are superior to those in(100)-oriented *** further use the diamond membranes to fabricate microring resonators with quality factors exceeding^*** by finite-difference time-domain calculations,we discuss the advantages of(111)-oriented structures as building blocks for quantum nanophotonic devices.

关键词： cavity color centers diamond

Therapeutic approach to emotional reactions accompanied with thermal skin injury–from basic to epidemiological research

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World Journal of Psychiatry 2024年第2期14卷 199-203页

作者： Bojana Krstic milos Krstic Dragica Selakovic Nemanja Jovicic Gvozden Rosic Department of Physiology Faculty of Medical SciencesUniversity of KragujevacKragujevac 34000Serbia Department of Histology and Embryology Faculty of Medical SciencesUniversity of KragujevacKragujevac 34000Serbia

In this editorial,we discuss the status of a therapeutic approach to emotional reactions accompanying thermal skin *** are considered a major health problem,as well as an economic and social problem,with potentially devastating and life-changing *** affect a wide range of patients with different damage mechanisms,varied depths,and localizations of the *** most common are thermal burns,with more than 11 million occurrences annually according to the World Health Organization *** skin injuries are among the most tragic and catastrophic injuries,almost unsurpassed in terms of severity,morbidity,and mortality,as well as functional,aesthetic,social,economic,and psychological *** survivors face stress,anxiety,depression,low self-esteem,body deformity,social isolation,unemployment,financial burden,and family *** advances in acute burn care have allowed researchers and physicians to pay more attention to other effects of burns,focusing on psychological consequences in *** from the significant improvements in routine protocols,it seems useful to take care of psychological disturbances that occur simultaneously but may emerge as the most lasting outcome of those *** that sense,various standards and additional approaches may be involved to achieve overall recovery.

关键词： Thermal skin injury Anxiety Depression Psychological consequences of burns

Non-thermal atmospheric-pressure positive pulsating corona discharge in degradation of textile dye Reactive Blue 19 enhanced by Bi_(2)O_(3) catalyst

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Plasma Science and Technology 2024年第2期26卷 104-113页

作者： Milica PETROVIC Dragan RADIVOJEVIC Sasa RANCEV Nena VELINOV milos KOSTIC Danijela BOJIC Aleksandar BOJIC Department of Chemistry Faculty of Sciences and MathematicsUniversity of NisNis 18000Serbia Department of Physics Faculty of Sciences and MathematicsUniversity of NisNis 18000Serbia

In this work,monoclinic Bi_(2)O_(3) was applied for the first time,to the best of our knowledge,as a catalyst in the process of dye degradation by a non-thermal atmospheric-pressure positive pulsating corona *** research focused on the interaction of the plasma-generated species and the catalyst,as well as the role of the catalyst in the degradation *** decomposition of the anthraquinone reactive dye Reactive Blue 19(RB 19) was performed in a selfmade reactor ***_(2)O_(3) was prepared by electrodeposition followed by thermal treatment,and characterized by x-ray diffraction,scanning electron microscopy and energy-dispersive xray *** was observed that the catalyst promoted decomposition of plasma-generated H_(2)O_(2) into ·OH radicals,the principal dye-degrading reagent,which further attacked the dye *** catalyst improved the decolorization rate by 2.5 times,the energy yield by 93.4%and total organic carbon removal by 7.1%.Excitation of the catalyst mostly occurred through strikes by plasma-generated reactive ions and radical species from the air,accelerated by the electric field,as well as by fast electrons with an energy of up to 15 eV generated by the streamers reaching the liquid *** strikes transferred the energy to the catalyst and created the electrons and holes,which further reacted with H_(2)O_(2) and water,producing ·OH *** was indentified as the primary role of the catalyst in this *** reactions followed pseudo first-order *** of H_(2)O_(2) and the dye degradation rate increased with increase in the input *** optimal catalyst dose was 500 mg·dm^(-3).The decolorization rate was a little lower in river water compared with that in deionized water due to the side reactions of ·OH radicals with organic matter and inorganic ions dissolved in the river water.

关键词： corona RB 19 Bi_(2)O_(3) catalyst degradation

Impact of alpha-synuclein pathology on adult neurogenesis: evidence for multilayered mechanisms

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Neural Regeneration Research 2022年第7期17卷 1491-1492页

作者： Jana Bonsberger Franziska Richter milos Stanojlovic Department of Pharmacology Toxicology and PharmacyUniversity of Veterinary MedicineHannoverGermany

Parkinson’s disease(PD)is the second most common neurodegenerative disease affecting 8–10 million people ***,PD is the fastest-growing neurodegenerative disease and it is predicted that the number of patients will double in the next thirty ***,PD is characterized by the presence of protein aggregations called Lewy bodies(LB)and by degeneration of dopaminergic neurons in the substantia nigra pars compacta.

关键词： degeneration pathology Impact

Cardiac Syndromes in Liver Disease:A Clinical Conundrum

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Journal of Clinical and Translational Hepatology 2023年第4期11卷 975-986页

作者： milos Brankovic Paul Lee Nikolaos Pyrsopoulos Mark Klapholz Department of Medicine Rutgers New Jersey Medical SchoolNewarkNJUSA Transatlantic Cardiovascular Study Group BloomfieldNJUSA Division of Gastroenterology and Hepatology Department of MedicineRutgers New Jersey Medical SchoolNewarkNJUSA Division of Cardiology Heart Failure Prevention and Treatment ProgramRutgers New Jersey Medical SchoolNewarkNJUSA

Understanding the interaction between the heart and liver is pivotal for managing patients in whom both organs are *** have shown that cardio-hepatic interactions are bidirectional and that their identification,assessment,and treatment remain *** hepatopathy is a condition that develops in the setting of long-standing systemic venous *** left untreated,congestive hepatopathy may lead to hepatic *** cardiogenic liver injury develops as a combination of venous stasis and sudden arterial hypoperfusion due to cardiac,circulatory,or pulmonary *** treatment of both conditions should be directed toward optimizing the cardiac *** syndrome may develop in patients with advanced liver disease and lead to multiorgan *** cardiomyopathy or abnormalities in pulmonary vasculature,such as hepatopulmonary syndrome and portopulmonary hypertension may also *** complication has unique treatment challenges and implications for liver *** presence of atrial fibrillation and atherosclerosis in liver disease brings another layer of complexity,particularly in terms of anticoagulation and statin *** article provides an overview of cardiac syndromes in liver disease,focusing on current treatment options and future perspectives.

关键词： Liver disease Congestive hepatopathy Cardiogenic liver injury Cirrhotic cardiomyopathy Hepatopulmonary syndrome Portopulmonary hypertension

Assessing Criteria Weights by the Symmetry Point of Criterion (Novel SPC Method)–Application in the Efficiency Evaluation of the Mineral Deposit Multi-Criteria Partitioning Algorithm

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Computer Modeling in Engineering & Sciences 2023年第7期136卷 955-979页

作者： Zoran Gligoric milos Gligoric Igor Miljanovic Suzana Lutovac Aleksandar Milutinovic Faculty of Mining and Geology University of BelgradeBelgrade11000Serbia

Information about the relative importance of each criterion or theweights of criteria can have a significant influence on the ultimate rank of ***,assessing the weights of criteria is a very important task in solving multi-criteria decision-making *** methods are commonly used for assessing the weights of criteria:objective,subjective,and integrated *** this study,an objective approach is proposed to assess the weights of criteria,called SPCmethod(Symmetry Point of Criterion).This point enriches the criterion so that it is balanced and easy to implement in the process of the evaluation of its influence on *** SPC methodology is systematically presented and supported by detailed calculations related to an artificial *** validate the developed method,we used our numerical example and calculated the weights of criteria by CRITIC,Entropy,Standard Deviation and MEREC *** analysis between these methods and the SPC method reveals that the developedmethod is a very reliable objective way to determine the weights of ***,in this study,we proposed the application of SPCmethod to evaluate the efficiency of themulti-criteria partitioning *** main idea of the evaluation is based on the following fact:the greater the uniformity of the weights of criteria,the higher the efficiency of the partitioning *** research demonstrates that the SPC method can be applied to solving different multi-criteria problems.

关键词： Multi-criteria decision-making weights of criteria symmetry point of criterion mineral deposit partitioning algorithm performance evaluation

Alexander disease:the road ahead

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Neural Regeneration Research 2023年第10期18卷 2156-2160页

作者： María A.Pajares Elena Hernández-Gerez milos Pekny Dolores Pérez-Sala Department of Structural and Chemical Biology Centro de Investigaciones Biológicas Margarita SalasMadridSpain Laboratory of Astrocyte Biology and CNS Regeneration Center for Brain RepairDepartment of Clinical NeuroscienceInstitute of Neuroscience and PhysiologySahlgrenska Academy at the University of GothenburgGothenburgSweden University of Newcastle NewcastleNSWand the Florey Institute of Neuroscience and Mental HealthParkvilleVICAustralia

Alexander disease is a rare neurodegenerative disorder caused by mutations in the glial fibrillary acidic protein,a type III intermediate filament protein expressed in *** early(infantile or juvenile)and adult onsets of the disease are known and,in both cases,astrocytes present characteristic aggregates,named Rosenthal *** are spread along the glial fibrillary acidic protein sequence disrupting the typical filament network in a dominant *** the presence of aggregates suggests a proteostasis problem of the mutant forms,this behavior is also observed when the expression of wild-type glial fibrillary acidic protein is ***,several isoforms of glial fibrillary acidic protein have been described to date,while the impact of the mutations on their expression and proportion has not been exhaustively ***,the posttranslational modification patterns and/or the protein-protein interaction networks of the glial fibrillary acidic protein mutants may be altered,leading to functional changes that may modify the morphology,positioning,and/or the function of several organelles,in turn,impairing astrocyte normal function and subsequently affecting *** particular,mitochondrial function,redox balance and susceptibility to oxidative stress may contribute to the derangement of glial fibrillary acidic protein mutant-expressing *** study the disease and to develop putative therapeutic strategies,several experimental models have been developed,a collection that is in constant *** fact that most cases of Alexander disease can be related to glial fibrillary acidic protein mutations,together with the availability of new and more relevant experimental models,holds promise for the design and assay of novel therapeutic strategies.

关键词： astrocytes endoplasmic reticulum stress glial fibrillary acidic protein mutants metabolism misassembly misfolding neurodegeneration oxidative stress posttranslational modifications unfolded protein response

Diabetes Prediction Algorithm Using Recursive Ridge Regression L2

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Computers, Materials & Continua 2022年第4期71卷 457-471页

作者： milos Mravik T.Vetriselvi K.Venkatachalam Marko Sarac Nebojsa Bacanin Sasa Adamovic Department of Computer Science Singidunum UniversityBelgrade11000Serbia Department of Computer science and Engineering K.Ramakrishnan College of TechnologyTrichy621112India Department of Applied Cybernetics Faculty of ScienceUniversity of Hradec Králové50003Hradec KrálovéCzech Republic

At present,the prevalence of diabetes is increasing because the human body cannot metabolize the glucose *** prediction of diabetes patients is an important research *** researchers have proposed techniques to predict this disease through data mining and machine learning *** prediction,feature selection is a key concept in ***,the features that are relevant to the disease are used for *** condition improves the prediction *** the right features in the whole feature set is a complicated process,and many researchers are concentrating on it to produce a predictive model with high *** this work,a wrapper-based feature selection method called recursive feature elimination is combined with ridge regression(L2)to form a hybrid L2 regulated feature selection algorithm for overcoming the overfitting problem of data *** is a major problem in feature selection,where the new data are unfit to the model because the training data are *** regression is mainly used to overcome the overfitting *** features are selected by using the proposed feature selection method,and random forest classifier is used to classify the data on the basis of the selected *** work uses the Pima Indians Diabetes data set,and the evaluated results are compared with the existing algorithms to prove the accuracy of the proposed *** accuracy of the proposed algorithm in predicting diabetes is 100%,and its area under the curve is 97%.The proposed algorithm outperforms existing algorithms.

关键词： Ridge regression recursive feature elimination random forest machine learning feature selection

Treatment options in stage I seminoma

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Oncology Research 2022年第3期30卷 117-128页

作者： UROS BUMBASIREVIC MARKO ZIVKOVIC milos PETROVIC VESNA CORIC NIKOLA LISICIC NEBOJSA BOJANIC Clinic of Urology University Clinical Center of SerbiaBelgrade11000Serbia Faculty of Medicine University of BelgradeBelgrade11000Serbia Institute of Medical and Clinical Biochemistry Faculty of MedicineUniversity of BelgradeBelgrade11000Serbia

Seminomas are most commonly diagnosed in clinical stage I(CSI).After orchiectomy,approximately 15%of patients in this stage have subclinical *** radiotherapy(ART)delivered to the retroperitoneum and ipsilateral pelvic lymph nodes has been the mainstay of treatment for many *** highly efﬁcient,with long-term cancer-speciﬁc survival(CSS)rates approaching almost 100%,ART is associated with considerable long-term consequences,particularly cardiovascular toxicity and increased risk of secondary malignancies(SMN).Therefore,active surveillance(AS)and adjuvant chemotherapy(ACT)were developed as alternative treatment *** AS prevents patient overtreatment,it is associated with strict follow-up regimens and increased radiation exposure due to repeated *** to equivalent CSS rates to ART,and lower toxicity,one course of adjuvant carboplatin presents the cornerstone of chemotherapy for CSI *** is almost 100%for patients with CSI seminoma,regardless of the chosen treatment ***,a personalized approach in treatment selection is ***,routine radiotherapy for CSI seminoma patients is no longer ***,it should be reserved for patients who are unﬁt or unwilling for AS or ***ﬁcation of prognostic factors for disease relapse allowed for the development of risk-adapted treatment strategy and stratiﬁcation of patients in low-risk and high-risk *** risk-adapted policy needs further validation,surveillance is currently recommended in low-risk patients,while ACT is reserved for patients with a higher risk of relapse.

关键词： Chemotherapy Radiotherapy Risk-adapted strategy Seminoma Surveillance