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The cell phone in the twenty-first century: Risk for addiction or ingestion? Case report and review of the literature

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World Journal of Emergency Medicine 2021年第4期12卷 335-336页

作者： Sanja Dragasevic milica stojkovic lalosevic Ljubisa Toncev Tamara Milovanovic Aleksandra Pavlovic Markovic Srdjan Djuranovic Dragan Popovic Clinic for Gastroenterology and Hepatology Clinical Center of SerbiaBelgrade 11000Serbia School of Medicine University of BelgradeBelgrade 11000Serbia

Dear editor,Foreign body ingestion and food bolus impaction are frequent emergency cases in clinical practice.[1] The majority of foreign body ingestion cases occur in the pediatric population, while individuals with mental illness,neurodevelopmental disorders, alcohol intoxication, and prisoners are recognized as a high-risk adult population for foreign body ingestion.

关键词： cases clinical editor

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Perineural invasion as a prognostic factor in patients with stage Ⅰ-Ⅲ rectal cancer –5-year follow up

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World Journal of Gastrointestinal Oncology 2020年第5期12卷 592-600页

作者： milica stojkovic lalosevic Tamara Milovanovic Marjan Micev Mirjana stojkovic Sanja Dragasevic Milos Stulic Ivan Rankovic Vladimir Dugalic Zoran Krivokapic Aleksandra Pavlovic Markovic Clinic for Gastroenterology and Hepatology Clinical Center of SerbiaBelgrade 11000Serbia School of Medicine University of BelgradeBelgrade 11000Serbia Clinic for Digestive Surgery-First Surgical Clinic Clinical Center of SerbiaBelgrade 11000Serbia

BACKGROUND Rectal cancer(RC)is one of the most common diagnosed cancers,and one of the major causes of cancer-related death *** of the current guidelines rely on TNM classification regarding therapy regiments,however recent studies suggest that additional histopathological findings could affect the disease *** To determine whether perineural invasion alone or in combination with lymphovascular invasion have an effect on 5-years overall survival(OS)of RC *** A prospective study included newly diagnosed stage I-III RC patients treated and followed at the Digestive Surgery Clinic,Clinical Center of Serbia,between the years of 2014–*** patients had their diagnosis histologically confirmed in accordance with both TMN and Dukes *** addition,the patient’s demographics,surgical details,postoperative pathological details,differentiation degree and their correlation with OS was *** Of 245 included patients with stage Ⅰ-Ⅲ RC,lymphovascular invasion(LVI)was identified in 92 patients(38%),whereas perineural invasion(PNI)was present in 46 patients(19%).Using Kaplan-Meier analysis for overall survival rate,we have found that both LVI and PNI were associated with lower survival rates(P<0.01).Moreover when Cox multiple regression model was used,LVI,PNI,older age,male gender were predictors of poor prognosis(HR=5.49;95%CI:2.889-10.429;P<0.05).CONCLUSION LVI and PNI were significant factors predicting worse prognosis in early and intermediate RC patients,hence more aggressive therapy should be reserved for these patients after curative resection.

关键词： Lymphovascular invasion Perineural invasion Rectal cancer

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