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Effect of pioglitazone on nerve conduction velocity of the median nerve in the carpal tunnel in type 2 diabetes patients

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World Journal of Diabetes 2016年第19期7卷 547-553页

作者： Sudip Chatterjee Debmalya Sanyal Sourav Das Choudhury mili bandyopadhyay Suraj Chakraborty Arabinda Mukherjee Department of Medicine Vivekananda Institute of Medical SciencesRamakrishna Mission Seva Pratishthan Department of Endocrinology KPC Medical CollegeRamakrishna Mission Seva Pratishthan Department of Medicine Gitaram Hospital Department of Neurology Vivekananda Institute of Medical SciencesRamakrishna Mission Seva Pratishthan

AIM To evaluate the impact of pioglitazone pharmacotherapy in median nerve electrophysiology in the carpal tunnel among type 2 diabetes *** The study was executed in patients with type 2 diabetes, treated with oral drugs, categorized under pioglitazone or non-pioglitazone group(14 in each group), and who received electrophysiological evaluation by nerve conduction velocity at baseline and 3 *** At 3 mo, pioglitazone-category had inferior amplitude in sensory median nerve [8.5 interquartile range(IQR) = 6.5 to 11.5) vs non-pioglitazone 14.5(IQR 10.5 to 18.75)](P = 0.002). Non-pioglitazone category displayed amelioration in amplitude in the sensory median nerve [baseline 13(IQR = 9 to 16.25) vs 3 mo 8.5(IQR = 6.5 to 11.5)](P = 0.01) and amplitude in motor median nerve [baseline 9(IQR = 4.75 to 11) vs 3 mo 6.75(IQR = 4.75 to 10.25)](P = 0.049); and deterioration of terminal latency of in motor ulnar nerve [baseline 2.07(IQR = 1.92 to 2.25) vs 3 mo 2.16(IQR = 1.97 to 2.325)](P = 0.043). There was amelioration of terminal latency in sensory ulnar nerve [baseline 2.45(IQR = 2.315 to 2.88) vs 3 mo 2.37(IQR = 2.275 to 2.445) for pioglitazone group(P = 0.038).CONCLUSION Treatment with pioglitazone accentuates probability of compressive neuropathy. In spite of comparable glycemic control over 3 mo, patients treated with pioglitazone showed superior electrophysiological parameters for the ulnar nerve. Pioglitazone has favourable outcome in nerve electrophysiology which was repealed when the nerve was subjected to compressive neuropathy.

关键词： Pioglitazone Adipocytes Diabetes mellitus Neuropathy Carpal tunnel

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Guest Editorial: State Estimation for Future Cyber-physical Power and Energy Systems:Challenges and Solutions

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Journal of Modern Power Systems and Clean Energy 2020年第4期8卷 595-596页

作者： Antonio Gomez-Exposito Lamine mili Wenchuan Wu Universidad de Sevilla Virginia Tech Tsinghua University

LARGE-SCALE renewable power plants and distributed generators are integrated in the electric power systems on the generation side,meanwhile new demand-response technologies are being deployed on the demand side,such a... 详细信息

关键词： power Power energy

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Determination of 15 phthalate esters in air by gas-phase and particle-phase simultaneous sampling

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Journal of Environmental Sciences 2017年第5期29卷 137-145页

作者： Chenchen Chi Meng Xia Chen Zhou Xueqing Wang mili Weng Xueyou Shen College of Environmental & Resource Sciences Zhejiang University Hangzhou 310058 China Zhejiang National Radiation Environmental Technology Co. Ltd. Hangzhou 310011 China School of Environmental and Resource Sciences Zhejiang Agriculture and Forestry University Hangzhou 310058 China Zhejiang Provincial Key Laboratory of Organic PollutionProcess and Control Hangzhou 3100S8 China

Based on previous research, the sampling and analysis methods for phthalate esters （PAEs） were improved by increasing the sampling flow of indoor air from 1 to 4 L/min, shortening the sampling duration from 8 to 2 hr. Meanwhile, through the optimization of chromatographic conditions, the concentrations of 9 additional PAE pollutants in indoor air were measured. The optimized chromatographic conditions required a similar amount of time for analysis as before, but gave high responsivity, the capability of simultaneously distinguishing 15 kinds of PAEs, and a high level of discrimination between individual sample peaks, as well as stable peak generation. The recovery rate of all gas-phase and particle-phase samples of the 15 kinds of PAEs ranged from 91.26% to 109.42%, meeting the quantitative analysis requirements for indoor and outdoor air sampling and analysis. For the first time, investigation of the concentration levels as well as characteristics of 15 kinds of PAEs in the indoor air from four different traffic micro-environments （private vehicles, busses, taxis and subways） was carried out, along with validation of the optimized sampling and analytical method. The results show that all the 9 additional PAEs could be detected at relatively high pollution levels in the indoor air from the four traffic micro-environments. As none of the pollution levels of the 15 kinds of PAEs in the indoor air from the 4 traffic micro-environments should be neglected, it is of great significance to increase the types of PAEs able to be detected in indoor air.

关键词： Air pollution Phthalate esters Traffic micro-environment Gas-phase and particle-phase Sampling and analytical method

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A mini-review of the electro-peroxone technology for wastewaters:Characteristics,mechanism and prospect

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Chinese Chemical Letters 2023年第9期34卷 7-14页

作者： Lu Chen Lanlan Wei Yifan Ru mili Weng Lin Wang Qizhou Dai College of Environment Zhejiang University of TechnologyHangzhou 310032China College of Environmental and Resources Sciences Zhejiang A&F UniversityHangzhou 311300China School of Biological and Chemical Engineering NingboTech UniversityNingbo 315100China

The electro-peroxone technology,a novel type of advanced oxidation technology,is widely used in wastewater ***,this paper reviews the advantages and problems of the electro-peroxone technology compared with electrochemical oxidation technology,ozonation technology,and traditional peroxone *** to the high kinetics of pollutant degradation,the electro-peroxone process can reduce the reaction time and energy consumption of pollutant treatment in *** electroperoxone technology can promote pollutant degradation and mineralization,which shows obvious synergistic effects of electrochemical oxidation and ozonation for wastewater *** importantly,the research mechanism of the electro-peroxone technology is systematically introduced from two aspects of cathode reaction and bulk *** influence of experimental parameters on the wastewater treatment effect is also ***,the potential applications and future research directions of the electro-peroxone technology in the wastewater field are *** electro-peroxone process can offer a highly efficient and energy saving water treatment method to improve the performance of existing ozonation and electrochemical systems and has therefore become a promising electrochemical advanced oxidation process for wastewater treatment.

关键词： The electro-peroxone technology Electrochemical oxidation‘Ozonation Hydrogen peroxide Wastewater treatment

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Multi-Agent Based Stochastic Dynamical Model to Measure Community Resilience

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Journal of Social Computing 2022年第3期3卷 262-286页

作者： Jaber Valinejad Lamine mili C.Natalie Van Der Wal Data and System Science Lab Harvard Medical SchoolHarvard UniversityCambridgeMA 02138USA Bradley Department of Electrical and Computer Engineering Virginia TechNorthern Virginia CenterFalls ChurchVA 22043USA Department of Multi-Actor Systems Faculty of TechnologyPolicy and ManagementDelft University of TechnologyDelft2600 AAthe Netherlands.

Emergency services and utilities need appropriate planning tools to analyze and improve infrastructure and community resilience to *** as a key metric of community resilience is the social well-being of a community during a disaster,which is made up of mental and physical social *** factors influencing community resilience directly or indirectly are emotional health,emergency services,and the availability of critical infrastructures services,such as food,agriculture,water,transportation,electric power,and communications *** turns out that in computational social science literature dealing with community resilience,the role of these critical infrastructures along with some important social characteristics is not *** address these weaknesses,we develop a new multi-agent based stochastic dynamical model,standardized by overview,design concepts,details,and decision(ODD+D)protocol and derived from neuro-science,psychological and social sciences,to measure community resilience in terms of mental and physical *** this model,we analyze the micro-macro level dependence between the emergency services and power systems and social characteristics such as fear,risk perception,informationseeking behaviour,cooperation,flexibility,empathy,and experience,in an artificial ***,we simulate this model in two case studies and show that a high level of flexibility,experience,and cooperation enhances community *** for both theory and practice are discussed.

关键词： community resilience collective behavior emergency services power systems critical infrastructures artificial society overview,design concepts,details,and decision(ODD+D) cyber-physical-social system

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Features and Formation Mechanism of Faults and Potash-forming Effect in the Lop Nur Salt Lake,Xinjiang,China

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Acta Geologica Sinica(English Edition) 2006年第6期80卷 936-943页

作者： LIU Chenglin WANG mili JIAO Pengcheng LI Shude CHEN Yongzhi School of Environmental Sciences Peking University Beijing 100871 Institute of Mineral Resources Chinese Academy of Geological Sciences Beijing 100037

The Lop Nur Salt Lake, located in the eastern part of the Tarim Basin, Xinjiang, China, has become a playa in the Quaternary. Rhombic in shape, the Lop Nur depression is mainly controlled by the NE-striking and nearly N-S-striking sets of faults. Since 1995, a superlarge brine potash deposit with potash resources of 2.50×10^8s t has been found in the Luobei subbasin in the northeastern part of the Lop Nur. We intensively studied the features and formation mechanism of faults inside the Lop Nur through satellite images, geomorphologic survey and continuous conductivity imaging and found seven subparallel graben faults formed under the action of nearly N 10° E principal compressional stress during deposition of the Lop Nur Salt Lake. These faults are up to 〉60 km long and 1-4 km wide and may extend downward for 1000 m or more. It is just under the action of these tensional faults that potash subbasius formed. The largest subbasin is the Luobei subbasin and the smaller ones are the Luoxi hollow, Erbei hollow and Tienan hollow. Investigation also indicates that the graben faults in the Lop Nur not only control the origin of the potash subbasins, but they themselves are also good brine reservoir structures, in which abundant potash-rich brines are stored. Therefore, The faults had played an important role in the potash formation of the Lop Nur.

关键词： Xinjiang Lop Nur salt lake fault potash formation

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Non-pulmonary allergic diseases and inflammatory bowel disease: A qualitative review

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World Journal of Gastroenterology 2014年第32期20卷 11023-11032页

作者： David S Kotlyar mili Shum Jennifer Hsieh Wojciech Blonski David A Greenwald Medical Oncology Service NIH National Can-cer InstituteNational Institutes of Health Department of Medicine New York/Presbyterian Medical CenterNew YorkNY 10021 United States Division of Gastroenterology Department of Med-icineSUNY Stony BrookStony Brook Department of Medicine SUNY Upstate Binghamton Campus BinghamtonNY 13902 United States Medical University 53-111 Wroclaw Poland Division of Gastroenterology and Liver Dis-eases Department of MedicineMontefiore Medical Center Albert Einstein College of Medicine Bronx

While the etiological underpinnings of inflammatory bowel disease(IBD) are highly complex, it has been not-ed that both clinical and pathophysiological similarities exist between IBD and both asthma and non-pulmonary allergic phenomena. In this review, several key points on common biomarkers, pathophysiology, clinical manifesta-tions and nutritional and probiotic interventions for both IBD and non-pulmonary allergic diseases are *** and mast cell activity show common behav-iors in both IBD and in certain allergic disorders. IgE also represents a key immunoglobulin involved in both IBD and in certain allergic pathologies, though these links require further study. Probiotics remain a critically important intervention for both IBD subtypes as well as multiple allergic phenomena. Linked clinical phenomena, especially sinonasal disease and IBD, are discussed. In addition, nutritional interventions remain an underuti-lized and promising therapy for modification of both al-lergic disorders and IBD. Recommending new mothers breastfeed their infants, and increasing the duration of breastfeeding may also help prevent both IBD and al-lergic diseases, but requires more investigation. While much remains to be discovered, it is clear that non-pulmonary allergic phenomena are connected to IBD in a myriad number of ways and that the discovery of com-mon immunological pathways may usher in an era of vastly improved treatments for patients.

关键词： Inflammatory bowel disease Ulcerative colitis Crohn's disease Food intolerance Food allergies Biomarkers Pathophysiology Nutrition Probiotics

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Maternal choledochal cysts in pregnancy:A systematic review of case reports and case series

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World Journal of Gastrointestinal Surgery 2023年第8期15卷 1784-1798页

作者： Goran Augustin Ivan Romic Iva miličić Mislav Mikuš Mislav Herman Department of Surgery School of MedicineUniversity of ZagrebZagreb 10000Croatia School of Medicine University of Zagreb Zagreb 10000Croatia Department of Surgery University Hospital Centre ZagrebZagreb 10000Croatia Department of Obstetrics and Gynecology University Hospital Centre ZagrebZagreb 10000Croatia

BACKGROUND Choledochal cysts(CC)are cystic dilatations of the biliary tract,usually diagnosed during childhood,with an estimated incidence in the general population of 1:*** related to CC include rupture,biliary obstruction,and *** CC in pregnancy are rarely reported,and there are no guidelines on optimal *** To systematically review maternal CC diagnosed during pregnancy or postpartum with regard to the clinical presentation of CC,the mode of treatment and delivery,and maternal *** A literature search of cases and case series of maternal CC in pregnancy and postpartum was conducted using MEDLINE/PubMed,Web of Science,Google Scholar,and *** were no restrictions on language or publication *** were lastly accessed on September 1,*** Overall,71 publications met the inclusion criteria,reporting 97 ***-eight cases were diagnosed during pregnancy and nine in the *** most common symptoms were abdominal pain(81.2%)and jaundice(60.4%).Interventions for CC complications were required in 52.5%of the cases,and 34%of pregnancies were *** cesarean section(CS)was done in 24.7%.The maternal mortality was 7.2%,while fetal mortality was inconsistently ***,CC>15 cm,and bilirubin levels>80 mmol/L were associated with a higher likelihood of urgent CS and surgical intervention for *** levels positively correlated with CC *** was no correlation between age and cyst dimension,gestational age at cyst discovery,and CC *** Although rare,maternal CC in pregnancy should be included in the evaluation of jaundice with upper abdominal *** and clinical course are variable,and treatment may range from an expectative approach to emergent surgical CC treatment and urgent *** most cases were managed by conservative measures or drainage procedures,CC>15 cm and progressive cholangitis carry the risk of CC rupture and septic

关键词： Choledochal cyst Pregnancy Cholangitis Surgery Delivery Cesarean section

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In situ formed Mg(BH_(4))_(2) for improving hydrolysis properties of MgH_(2)

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Journal of Magnesium and Alloys 2024年第3期12卷 1204-1214页

作者： Yongyang Zhu mili Liu liming Zeng Yin Wang Daifeng Wu Rui Li Qing Zhou Renheng Tang Fangming Xiao Institute of Resources Utilization and Rare Earth Development Guangdong Provincial Key Laboratory of Rare Earth Development and ApplicationGuangdong Academy of SciencesGuangzhou 510650China School of Materials Science and Engineering Guangdong Provincial Key Laboratory of Advanced Energy Storage MaterialsSouth China University of TechnologyGuangzhou 510641China

The hydrolysis of MgH_(2) delivers high hydrogen capacity(15.2 wt%),which is very attractive for real-time hydrogen ***,the formation of a surface passivation Mg(OH)_(2) layer and the large excess of H_(2)O required to ensure complete hydrolysis are two key challenges for the MgH_(2) hydrolysis ***,a low-cost method is reported to synthesize MgH_(2)@Mg(BH_(4))_(2) composite via ball-milling MgH_(2) with cheap and widely available B_(2)O_(3)(or B(OH)_(3)).By adding small amounts of B_(2)O_(3),the in-situ formed Mg(BH_(4))_(2) could significantly promote the hydrolysis of MgH_(2).In particular,the MgH_(2)–10 wt%B_(2)O_(3) composite releases 1330.7 mL·g^(−1) H_(2)(close to 80%theoretical hydrogen generation H_(2))in H_(2)O and 1520.4 mL·g^(−1) H_(2)(about 95%)in 0.5 M MgCl_(2) in 60 min at 26℃ with hydrolysis rate of 736.9 mL·g^(−1)·min^(−1) and 960.9 mL·g^(−1)·min^(−1) H_(2) during the first minute of the hydrolysis,*** addition,the MgCl_(2) solution allows repeated use by filtering and exhibits high cycle stability(20 cycles),therefore leading to much reduced capacity loss caused by the excess H_(2)*** show that by introducing B_(2)O_(3) and recycling the 0.5 M MgCl_(2) solution,the system hydrogen capacity can approach 5.9 wt%,providing a promising hydrogen generation scheme to supply hydrogen to the fuel cells.

关键词： Hydrolysis MgH_(2) Mg(BH_(4))_(2) Hydrogen generation B_(2)O_(3) MgCl_(2)

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Treatment of Chronic Heart Failure Complicated with Anxiety and Depression Using Traditional Chinese and Western Medicine

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Journal of Clinical and Nursing Research 2022年第4期6卷 83-88页

作者： mili Dong Hong Fan Shaanxi University of Traditional Chinese Medicine Xianyang 712046Shaanxi ProvinceChina Shaanxi Provincial Hospital of Traditional Chinese Medicine Xi’an 712000Shaanxi ProvinceChina

Chronic heart failure(CHF)is the terminal stage of various heart diseases,and is the main cause of death from cardiovascular *** recent years,the prevalence of CHF combined with anxiety and depressive state has shown an upward trend,and this paper was aimed to provide a reference for the diagnosis and treatment of CHF combined with anxiety and depression using Traditional Chinese medicine(TCM)and Western medicine.

关键词： Chronic heart failure Anxiety Depression TCM therapy Western medicine therapy

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