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Factors affecting complications development and mortality after single lung transplant

World Journal of Transplantation 2021年第8期11卷 320-334页

作者： Metodija Sekulovski Bilyana Simonska milena Peruhova Boris Krastev Monika Peshevska-Sekulovska Lubomir Spassov Tsvetelina Velikova Department of Anesthesiology and Intensive care University Hospital LozenetzSofia 1407Bulgaria Medical Faculty Sofia University St.Kliment OhridskiSofia 1407Bulgaria Department of Gastroenterology University Hospital LozenetzSofia 1407Bulgaria Department of Clinical Oncology MHAT Hospital for Women Health NadezhdaSofia 1330Bulgaria Department of Cardiothoracic Surgery University Hospital LozenetzSofia 1431Bulgaria Department of Clinical Immunology University Hospital LozenetzSofia 1407Bulgaria

Lung transplantation(LT)is a life-saving therapeutic procedure that prolongs survival in patients with end-stage lung ***,as a therapeutic option for high-risk candidates,single LT(SLT)can be feasible because the immediate morbidity and mortality after transplantation are lower compared to sequential single(double)LT(SSLTx).Still,the long-term overall survival is,in general,better for *** the great success over the years,the early post-SLT period remains a perilous time for these *** who undergo SLT are predisposed to evolving early or late postoperative *** review emphasizes factors leading to post-SLT complications in the early and late periods including primary graft dysfunction and chronic lung allograft dysfunction,native lung complications,anastomosis complications,infections,cardiovascular,gastrointestinal,renal,and metabolite complications,and their association with morbidity and mortality in these ***,we discuss the incidence of malignancy after SLT and their correlation with immunosuppression therapy.

关键词： Lung transplantation Single lung transplant Primary graft dysfunction Native lung complications Technical transplant complications Vascular transplant complications Graft rejection De novo malignancy

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人体仿生哲学——milena Krais的家具设计

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现代装饰（家居） 2012年第12期 24-25页

作者：陈雅男 milena Krais 肖俊

2010年,Driade的人面椅在米兰家具展中大放异彩,它通过Art Deco艺术装饰的精准表达,意为向人体本身表以致敬,也让仿生设计迈入了新的一页。从最初功能上的符合人体工学,再至人体形态或结构上的模拟,不时能看到普通家具中横亘出一条腿,... 详细信息

2010年,Driade的人面椅在米兰家具展中大放异彩,它通过Art Deco艺术装饰的精准表达,意为向人体本身表以致敬,也让仿生设计迈入了新的一页。从最初功能上的符合人体工学,再至人体形态或结构上的模拟,不时能看到普通家具中横亘出一条腿,更有那些所谓女体盛宴的"艺术"装置,不同的设计带来视觉感官上的极大冲击,也进一步细化并定义了仿生设计的另一支脉络一一人体仿生设计学。milena Krais是一位年轻的德国家具设计师,最初攻读时装设计专业,但她似乎对产品设计更情有独钟,进修"

关键词：家具设计 milena Krais 仿生设计人体工学视觉感官产品设计艺术装饰家具展时装设计人体形态

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Degradation of Cymodocea nodosa(Ucria)Ascherson meadow at Las Canteras Beach(Gran Canaria,Canary Islands,Atlantic Ocean)

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Journal of Coastal Life Medicine 2014年第4期 270-273页

作者： milena Polifrone Miquel Rosell-Fieschi Departamento de Biología Universidad de Las Palmas de Gran Canaria-Campus Universitario de Tafira35017 Las PalmasCanary IslandsSpain

Objective:To monitor the distribution of Cymodocea nodosa(Ucria)Ascherson in Las Canteras Beach(Las Palmas de Gran Canaria,Spain),comparing the status in 2005 with the distribution observed in 1985 and ***:Field observations by selfcontained underwater breathing apparatus diving records and cartographic ***:The seagrass meadow originally distributed between the beach and a bar of volcanic rocks,which sheltered it from the strong north-east winds and *** 1985 a gradual reduction of its extent has been observed and more than 80%of the original canopy disappeared in twenty years time,mostly due to the anthropogenic impact and modification of the sedimentary dynamics of the ***:The degradation of this seagrass meadow determinates the loss of the only meadow in the north of the island of Gran Canaria and the absence of a management plan for its conservation.

关键词： Anthropogenic impact Conservation biology Cymodocea nodosa Distribution Seagrasses Sediment burial

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CALCULATION OF THE GIBBS DERIVATIVES ON FINITE ABELIAN GROUPS THROUGH THE DECISION DIAGRAMS

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Analysis in Theory and Applications 1998年第4期14卷 12-25页

作者： Radomir S. Stankovic milena Stankovc Electronics ■Yugoslavia Electronics ■Yugoslavia

Paper considers the calculation of the values of Gibbs derivatives on finite Abelian groups. The calculation procedure is based upon the decision diagram representation of functions defined on finite Abelian groups. A... 详细信息

关键词： der APPI CALCULATION OF THE GIBBS DERIVATIVES ON FINITE ABELIAN GROUPS THROUGH THE DECISION DIAGRAMS

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基于多向特征金字塔的轻量级目标检测算法

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液晶与显示 2021年第11期36卷 1516-1524页

作者：白创王英杰闫昱 DJUKANOVIC milena 长沙理工大学物理与电子科学学院湖南长沙410114 柔性电子材料基因工程湖南省重点实验室湖南长沙410114 黑山大学电气工程学院黑山共和国波德戈里察81000

针对实时目标检测算法Tiny YOLOv3存在的深层特征难以提取、实时性不能满足需求、边界框定位不够准确的问题,提出一种改进的轻量级检测模型MTYOLO(MdFPN Tiny YOLOv3)。该模型构造多向特征金字塔网络(MdFPN)代替简单级联,充分完成了多... 详细信息

针对实时目标检测算法Tiny YOLOv3存在的深层特征难以提取、实时性不能满足需求、边界框定位不够准确的问题,提出一种改进的轻量级检测模型MTYOLO(MdFPN Tiny YOLOv3)。该模型构造多向特征金字塔网络(MdFPN)代替简单级联,充分完成了多层语义信息的提取与融合;使用深度可分离卷积代替标准卷积,有效降低网络复杂度,提升了检测的实时性能;采用Complete IOU loss(CIOU loss)代替MSE作为回归损失函数,极大地提高了边界框的回归精度。在PASCAL VOC和COCO数据集上对MTYOLO进行测试,结果表明,改进后模型的mAP最高可达到83.7%,检测速度最快可达到205 fps。

关键词：目标检测特征金字塔网络深度可分离卷积 Complete IOU loss

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Outcome of endotherapy for pancreas divisum in patients with acute recurrent pancreatitis

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World Journal of Gastroenterology 2014年第46期20卷 17468-17475页

作者： Alberto Mariani milena Di Leo Maria Chiara Petrone Paolo Giorgio Arcidiacono Antonella Giussani Raffaella Alessia Zuppardo Giulia Martina Cavestro Pier Alberto Testoni Gastroenterology and Gastrointestinal Endoscopy Unit Division of Experimental OncologyIRCCS San Raffaele Scientific Institute - Vita Salute San Raffaele University20132 MilanItaly

AIM: To assess the rate of relapses of acute pancreatitis (AP), recurrent AP (RAP) and the evolution of endosonographic signs of chronic pancreatitis (CP) in patients with pancreas divisum (PDiv) and RAP.

关键词： Endoscopic retrograde cholangiopancreatography Magnetic resonance cholangiopancreatography with secretin stimulation Minor papilla endotherapy Pancreatic stenting Endoscopic ultrasonography

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Comparison of ICare and IOPen vs Goldmann applanation tonometry according to international standards 8612 in glaucoma patients

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International Journal of Ophthalmology(English edition) 2016年第11期9卷 1624-1628页

作者： milena Pahlitzsch Jeanette Brünner Johannes Gonnermann Anna-Karina B.Maier Necip Torun Eckart Bertelmann Matthias KJ.Klamann Glaucoma and Retinal Degeneration Research Group UCLInstitute of Ophthalmology Department of Ophthalmology Campus Virchow ClinicCharite University MedicineAugustenburger Platz 1

AIM： To compare IOPen and ICare rebound tonometry to Goldmann applanation tonometry（GAT） according to International Standards Organization（ISO） 8612 ***： Totally 191 eyes（n =107 individuals） were included. Criteria of ISO 8612 were fulfilled： 3 clusters of IOP, measured by GAT, were formed. The GAT results were given as mean±standard ***： GAT（19.7±0.5 mm Hg） showed a significant correlation to ICare（19.8±0.5 mm Hg）（r =0.547, P 〈0.001）and IOPen（19.5 ±0.5 mm Hg）（r =0.526, P 〈0.001）.According to ISO 8612 criteria in all 3 IOP groups the number of outliers（of the 95% limits of agreement）exceeded 5% for ICare and IOPen vs GAT： No.1（n =68）29.4% and 22.1%, No.2（n =62） 35.5% and 37.1%, No.3（n =61） 26.2% and 42.6%, ***： The strict requirements of the ISO 8612 are not fulfilled in a glaucoma collective by ICare and IOPen at present. As long as the Goldmann tonometry is applicable it should be used first of all for reproducible IOP readings. ICare and IOPen tonometry should be considered as an alternative tool, if application of Goldmann tonometry is not possible.

关键词： ICare tonometry IOPen tonometry Goldmann applanation tonometry glaucoma intraocularpressure

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^(11)C-PK11195 plasma metabolization has the same rate in multiple sclerosis patients and healthy controls:a cross-sectional study

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Neural Regeneration Research 2021年第12期16卷 2494-2498页

作者： Aline Morais de Souza milena Sales Pitombeira Larissa Estessi de Souza Fabio Luiz Navarro Marques Carlos Alberto Buchpiguel Caroline Cristiano Real Daniele de Paula Faria Laboratory of Nuclear Medicine(LIM43) Department of Radiology and OncologyFaculdade de Medicina FMUSPUniversidade de Sao PauloSao PauloSPBrazil Department of Neurology Faculdade de Medicina FMUSPUniversidade de Sao PauloSao PauloSPBrazil

^(11)C-PK11195 is a positron emitter tracer used for Positron Emission Tomography(PET)imaging of innate immune cell activation in studies of neuroinflammatory *** the image quantitative analysis,it is necessary to quantify the intact fraction of this tracer in the arterial plasma during imaging acquisition(plasma intact fraction).Due to the complexity and costs involved in this analysis it is important to evaluate the real necessity of individual analysis in each 11C-PK11195 PET imaging *** purpose of this study is to compare 11CPK11195 plasma metabolization rate between healthy controls and multiple sclerosis(MS)patients and evaluate the interference of sex,age,treatment,and disease phenotype in the tracer intact fraction measured in arterial plasma samples.11C-PK11195 metabolization rate in arterial plasma was quantified by high performance liquid chromatography in samples from MS patients(n=50)and healthy controls(n=23)at 20,45,and 60 minutes after 11C-PK11195 *** were also stratified by sex,age,treatment type,and MS *** results showed no significant differences in the metabolization rate of healthy controls and MS patients,or in the stratified *** conclusion,11C-PK11195 metabolization has the same rate in patients with MS and healthy controls,which is not affected by sex,age,treatment,and disease ***,these findings could contribute to exempting the necessity for tracer metabolization determination in all 11C-PK11195 PET imaging acquisition,by using a population metabolization rate *** study procedures were approved by the Ethics Committee for Research Projects Analysis of the Hospital das Clinicas of the University of Sao Paulo Medical School(approval No.624.065)on April 23,2014.

关键词： ^(11)C-PK11195 HPLC kinetic modeling metabolization multiple sclerosis neuroinflammation PET imaging PET tracer radiometabolites

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Diagnosis, treatment, and current concepts in the endoscopic management of gastroenteropancreatic neuroendocrine neoplasms

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World Journal of Gastroenterology 2022年第34期28卷 4943-4958页

作者： Giuseppe Iabichino milena Di Leo Monica Arena Giovanni Giuseppe Rubis Passoni Elisabetta Morandi Francesca Turpini Paolo Viaggi Carmelo Luigiano Luca De Luca Digestive Endoscopy Unit ASST Santi Paolo e CarloMilano 20144Italy Gastroenterology Section Grande Ospedale Metropolitano“Bianchi-Melacrino-Morelli”Reggio Calabria 89124Italy

Gastroenteropancreatic neuroendocrine neoplasms(GEP-NENs)are rare tumors derived from the neuroendocrine cell system,which that have increased in incidence and prevalence in recent *** improvements in radiological and metabolic imaging,endoscopy still plays a pivotal role in the number of *** detection,characterization,and staging are essential in management and treatment *** and lower gastrointestinal(GI)endoscopy is essential for correct localization of the primary tumor site of GI *** ultrasonography(EUS)has an important role in the imaging and tissue acquisition of pancreatic NENs and locoregional staging of GI neuroendocrine *** staging and histological diagnosis have important prognostic *** operating techniques allow the removal of small GI NENs in the early stage of mucosal or submucosal invasion of the intestinal *** EUS-guided techniques may help the surgeon locate small and deep tumors,thus avoiding formal pancreatic resections in favor of parenchymal-sparing ***,locoregional ablative treatments have been proposed in recent studies with promising results in selected patients.

关键词： Neuroendocrine neoplasms Gastrointestinal endoscopy Endoscopic resection Endoscopic ultrasound Ablative technique Tissue acquisition

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Encephalic hemodynamic phases in subarachnoid hemorrhage:how to improve the protective effect in patient prognoses

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Neural Regeneration Research 2015年第5期10卷 748-752页

作者： Marcelo de Lima Oliveira Daniel Silva de Azevedo milena Krajnyk de Azevedo Ricardo de Carvalho Nogueira Manoel Jacobsen Teixeira Edson Bor-Seng-Shu Division of Neurological Surgery Hospital das ClinicasSchool of MedicineUniversity of Sao Paulo

Subarachnoid hemorrhage is frequently associated with poor prognoses. Three different hemo- dynamic phases were identified during subarachnoid hemorrhage： oligemia, hyperemia, and vasospasm. Each phase is associated with brain metabolic changes. In this review, we correlated the hemodynamic phases with brain metabolism and potential treatment options in the hopes of improving patient prognoses.

关键词： hemodynamic phases cerebral subarachnoid hemorrhage metabolic crises

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