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Root pruning is effective in alleviating the inhibition of soybean growth caused by anaerobic stress for a short period

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Journal of Integrative Agriculture 2023年第4期22卷 1035-1044页

作者： Koji YAMANE miki mariyama Yoshihiro HIROOKA Morio IIJIMA Graduate School of Agriculture Kindai UniversityNara 631-8505Japan

Soybean is an important upland crop,but its productivity is often limited by anaerobic stress caused by *** ability to adjust root growth under environmental constraints is an important physiological trait for adapting to an everchanging environment,and root pruning is an artificial technique for regenerating the root *** the present study,we investigated whether root pruning in soybean can effectively alleviate the inhibitory effects of anaerobic *** plants were affected by anaerobic stress at the germination,vegetative stage 1(V1),and reproductive stage 1(R1)stages,and then the plants were treated with root pruning just after the stress *** plants at the germination stage were treated with root cap and tip removals after hypoxia(N_(2)treatment).Root cap removal was more effective in suppressing the inhibitory effects of hypoxia than root tip removal(5 mm from the tip).The shoot dry weights of the soybean plants with and without root cap removal after hypoxia were 51.2 and 73.8%of the control,respectively,while the root dry weights of plants with and without root cap removal after hypoxia were 43.2 and 62.8%of the control,*** root cap removal effectively enhanced soybean growth after anaerobic stress,the root cap may be the candidate tissue for the stress memory *** soybean plants at the V1 stage of growth were affected by anaerobic stress,the branch number,pod weight in the main stem,root length,and root surface area of the soybean plants treated with anaerobic stress at the R1 stage significantly decreased compared with those of the *** contrast,root pruning(2 mm from the tip)immediately after the stress treatment enhanced root growth,branch number,and pod *** branch number,pod weight,root length,and root surface area of the plants treated with root pruning were 1.13,1.14,1.12,and 1.13 times higher than those of plants treated with anaerobic *** was observed in the roo

关键词： crack fertilization nodulation control root cap removal stress memory waterlogging

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Intranasal administration of stem cell-derived exosomes for central nervous system diseases

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Neural Regeneration Research 2024年第6期19卷 1249-1255页

作者： Shuho Gotoh Masahito Kawabori miki Fujimura Department of Neurosurgery Hokkaido University Graduate School of Medicine

Exosomes, lipid bilayer-enclosed small cellular vesicles, are actively secreted by various cells and play crucial roles in intercellular communication. These nanosized vesicles transport internalized proteins, mRNA, miRNA, and other bioactive molecules. Recent findings have provided compelling evidence that exosomes derived from stem cells hold great promise as a therapeutic modality for central nervous system disorders. These exosomes exhibit multifaceted properties including antiapoptotic, anti-inflammatory, neurogenic, and vasculogenic effects. Furthermore, exosomes offer several advantages over stem cell therapy, such as high preservation capacity, low immunogenicity, the ability to traverse the blood-brain barrier, and the potential for drug encapsulation. Consequently, researchers have turned their attention to exosomes as a novel therapeutic avenue. Nonetheless, akin to the limitations of stem cell treatment, the limited accumulation of exosomes in the injured brain poses a challenge to their clinical application. To overcome this hurdle, intranasal administration has emerged as a non-invasive and efficacious route for delivering drugs to the central nervous system. By exploiting the olfactory and trigeminal nerve axons, this approach enables the direct transport of therapeutics to the brain while bypassing the blood-brain barrier. Notably, exosomes, owing to their small size, can readily access the nerve pathways using this method. As a result, intranasal administration has gained increasing recognition as an optimal therapeutic strategy for exosomebased treatments. In this comprehensive review, we aim to provide an overview of both basic and clinical research studies investigating the intranasal administration of exosomes for the treatment of central nervous system diseases. Furthermore, we elucidate the underlying therapeutic mechanisms and offer insights into the prospect of this approach.

关键词： central nervous system disease exosome extracellular vesicle intranasal administration stem cell

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A Hydrogen-Bonded,Hexagonally Networked,Layered Framework with Large Aperture Designed by Structural Synchronization of a Macrocycle and Supramolecular Synthon

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Precision Chemistry 2024年第5期2卷 221-228页

作者： Hiroki Yoshimura Ryusei Oketani miki Naruoka Norimitsu Tohnai Ichiro Hisaki Division of Chemistry Graduate School of Engineering ScienceOsaka UniversityToyonakaOsaka 560-8531Japan Department of Applied Chemistry Graduate School of EngineeringOsaka UniversitySuitaOsaka 565-0871Japan

To develop porous organic frameworks,precise control of the stacking manner of two-dimensional porous motifs and structural characterization of the resultant framework are *** these points of view,porous molecular crystals formed through reversible intermolecular hydrogen bonds,such as;hydrogen-bonded organic frameworks(HOFs),can provide deep insight because of their high crystallinity,affording single-crystalline X-ray diffraction *** this study,we demonstrate that the stacking manner of hydrogen-bonded hexagonal network(HexNet)sheets can be controlled by synchronizing a homological triangular macrocyclic tecton and a hydrogen-bonded cyclic supramolecular synthon called the phenylene triangle.A structure of the resultant HOF was crystallographically characterized and revealed to have a large channel aperture of 2.4 *** HOF also shows thermal stability up to 290°C,which is higher than that of the conventional HexNet frameworks.

关键词： hydrogen-bonded organicframeworks hexagonalnetwork macrocycle carboxylicacid porosity

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Giant Brunner's gland hyperplasia of the duodenum successfully resected en bloc by endoscopic mucosal resection: A case report

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World Journal of Gastrointestinal Endoscopy 2024年第6期16卷 368-375页

作者： Makomo Makazu Akiko Sasaki Chikamasa Ichita Chihiro Sumida Takashi Nishino miki Nagayama Shinichi Teshima Gastroenterology Medicine Center Shonan Kamakura General HospitalKamakura 247-8533Japan Department of Gastroenterology Shonan Kamakura General HospitalKanagawa 247-8533Japan Department of Pathology Shonan Kamakura General HospitalKamakura 247-8533Japan

BACKGROUND Duodenal Brunner's gland hyperplasia(BGH)is a therapeutic target when complications such as bleeding or gastrointestinal obstruction occur or when malignancy cannot be ruled ***,we present a case of large BGH treated with endoscopic mucosal resection(EMR).CASE SUMMARY An 83-year-old woman presented at our hospital with *** tests revealed severe anemia,esophagogastroduodenoscopy showed a 6.5 cm lesion protruding from the anterior wall of the duodenal bulb,and biopsy revealed the presence of glandular *** ultrasonography(EUS)demonstr-ated relatively high echogenicity with a cystic *** muscularis propria was slightly elevated at the base of the *** was performed without *** formalin-fixed lesion size was 6 cm×3.5 cm×3 cm,showing nodular proliferation of non-dysplastic Brunner's glands compartmentalized by fibrous septa,confirming the diagnosis of *** of EMR or hot snare polypectomy are rare for duodenal BGH>6 *** this case,the choice of EMR was made by obtaining information on the base of the lesion as well as on the internal characteristics through *** Large duodenal lesions with good endoscopic maneuverability and no evident muscular layer involvement on EUS may be resectable via EMR.

关键词： Duodenum Brunner’s gland hyperplasia Brunner’s gland hamartoma Brunner’s gland adenoma Endoscopic mucosal resection Case report

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中日高中生汉语教材比较研究 ——以《高校生からの中国語》（从高中学起的汉语）与《跟我学汉语》（日语版）为例

中日高中生汉语教材比较研究 ——以《高校生からの中国語》（从...

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作者：本夛美季（HONDA miki）华东师范大学

学位级别：硕士

日本具有悠久的学习和使用汉语的历史,并且一直致力于推广汉语教育,这一点与其他国家相比尤其特殊。自中国汉朝开始,日本就着力推进汉语教育,而明治时期出版的教材《亚细亚言语集》,是日本第一部北京官方语言的教材,由日本学者广部精编... 详细信息

日本具有悠久的学习和使用汉语的历史,并且一直致力于推广汉语教育,这一点与其他国家相比尤其特殊。自中国汉朝开始,日本就着力推进汉语教育,而明治时期出版的教材《亚细亚言语集》,是日本第一部北京官方语言的教材,由日本学者广部精编写,它对日本汉语教育的发展起到了极其重要的作用。中国的改革开放在日本也快速掀起了一股“汉语热”。尽管日本本土出版了众多版本的汉语教材,但是缺乏具有权威性的汉语教材,而中国编辑出版的对日汉语教材在针对性方面又值得商榷。目前,针对对日汉语教材的比较研究寥寥无几,各种版本的日本汉语教材各自的特色与优缺点无法体现。因此有必要对这些教材进行比较研究,为编写具有针对性的对日汉语教材提供依据,以满足如此众多汉语学习者,特别是青少年汉语学习者的需求。本文基于实用性、针对性、趣味性、丰富性等教材编写理论,利用文献资料法、数据统计法与比较归纳法等方法,从语音、词汇、语法、汉字、练习、话题、文化、插图和课文等多个方面入手,对两套具有代表性的对日汉语教材《高校生からの中国語》(从高中学起的汉语)与《跟我学汉语》(日语版)进行全面的量化比较研究,揭示两套教材在选材、编写理念、文化内涵、侧重点等方面的异同,获得关于两套教材内容逐项量化统计与比较分析结果,佐证两套教材存在的优缺点,指出两部教材的互补性,并提出了相应的建议。希望本文的研究结果将有助于教材编写者,结合日本文化背景以及日本人的思维习惯,编写具有针对性的高质量的初级对日汉语教材。

关键词：《高校生からの中国語》(从高中学起的汉语) 《跟我学汉语》(日语版) 国际中文教育初级汉语教材教材对比

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Effect of hydrogen peroxide on selective flotation of chalcocite and enargite

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International Journal of Mining Science and Technology 2023年第6期33卷 703-716页

作者： Gde Pandhe Wisnu Suyantara Daniyarov Berdakh Hajime miki Tsuyoshi Hirajima Keiko Sasaki Daishi Ochi Yuji Aoki Department of Earth Resources Engineering Faculty of EngineeringKyushu UniversityFukuoka 819-0395Japan Kyushu University Institute for Asian and Oceanian Studies Kyushu UniversityFukuoka 819-0395Japan Graduate School of Engineering Faculty of EngineeringKyushu UniversityFukuoka 819-0395Japan Uzbekistan-Japan Innovation Center of Youth Tashkent 100095Uzbekistan Sumitomo Metal Mining Co. Ltd.Tokyo 105-8716Japan Sumitomo Metal Mining Co. Ltd.Ehime 792-0002Japan

Enargite is typically associated with *** to the similarity in the flotation behaviors of these minerals,both minerals are reported to concentrate in the conventional flotation ***,inorganic arsenic in enargite can decrease the copper concentrate quality and increase the operating cost of processing this *** these minerals is important for cleaner copper production to avoid these *** this context,this study investigated the effect of hydrogen peroxide(H_(2)O_(2))treatment on the flotation behavior of chalcocite and *** tests of pure and mixed minerals indicated that H_(2)O_(2)treatment reduced the floatability of chalcocite and enargite by forming sulfate and copper hydroxide on their *** the detrimental effect of the H_(2)O_(2)treatment,there was a narrow window of H_(2)O_(2)concentration for separating both minerals,in which enargite floated and chalcocite was *** selective flotation behavior was caused by the rapid adsorption of potassium amyl xanthate(KAX)and lower surface oxidation of enargite compared with that of chalcocite.

关键词： Enargite Chalcocite Hydrogen peroxide Potassium amyl xanthate Selective flotation

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Quest towards ultimate performance in superconducting nanowire single photon detectors

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Science China(Physics,Mechanics & Astronomy) 2018年第2期61卷 80-81页

作者： Shigehito miki Advanced ICT Research Institute National Institute of Information and Communications Technology

In 2007,superconducting nanowire single photon detectors(SSPD or SNSPD)[1]made an outstanding impact in the field of quantum information technology by demonstrating quantum key distribution(QKD)over a 200-km optical fiber with a 42-dB optical loss using a practical SNSPD system[2].This successful demonstration was realized thanks to its

关键词： SDE Quest towards ultimate performance in superconducting nanowire single photon detectors

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Towards high-throughput many-body perturbation theory: efficient algorithms and automated workflows

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npj Computational Materials 2023年第1期9卷 1609-1618页

作者： miki Bonacci Junfeng Qiao Nicola Spallanzani Antimo Marrazzo Giovanni Pizzi Elisa Molinari Daniele Varsano Andrea Ferretti Deborah Prezzi FIM Department University of Modena and Reggio EmiliaVia Campi 213/aModenaItaly S3 Center Istituto NanoscienzeCNRVia Campi 213/aModenaItaly Theory and Simulation of Materials(THEOS)and National Centre for Computational Design and Discovery of Novel Materials(MARVEL) École Polytechnique Fédérale de LausanneCH-1015 LausanneSwitzerland Dipartimento di Fisica Universitàdi TriesteI-34151 TriesteItaly Laboratory for Materials Simulations(LMS) Paul Scherrer Institut(PSI)CH-5232 Villigen PSISwitzerland

The automation of ab initio simulations is essential in view of performing high-throughput(HT)computational screenings oriented to the discovery of novel materials with desired physical *** this work,we propose algorithms and implementations that are relevant to extend this approach beyond density functional theory(DFT),in order to automate many-body perturbation theory(MBPT)***,an algorithm pursuing the goal of an efficient and robust convergence procedure for GW and BSE simulations is provided,together with its implementation in a fully automated *** is accompanied by an automatic GW band interpolation scheme based on maximally localized Wannier functions,aiming at a reduction of the computational burden of quasiparticle band structures while preserving high *** proposed developments are validated on a set of representative semiconductor and metallic systems.

关键词： properties perturbation theory

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Blood Pressure Lowering for the Secondary Prevention of Stroke

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Cardiology Discovery 2022年第1期2卷 51-57页

作者： Shunsuke Funakoshi miki Kawazoe Kazuhiro Tada Makiko Abe Hisatomi Arima Department of Preventive Medicine and Public Health Faculty of MedicineFukuoka UniversityFukuoka 814-0180Japan Department of Neurology Faculty of MedicineFukuoka UniversityFukuoka 814-0180Japan Division of Nephrology and Rheumatology Department of Internal MedicineFaculty of MedicineFukuoka UniversityFukuoka 814-0180Japan.

Hypertension is one of the most important modifiable risk factors for stroke,and greater than 50%of all stroke events are estimated to be attributable to elevated blood pressure(BP).Randomized trials and meta-analyses have demonstrated that reducing BP is the most effective and generalizable strategy for preventing recurrent *** on currently available evidence,BP should be reduced to below 140/90 mmHg in all patients during the chronic post-stroke phase and to below 130/80 mmHg when welltolerated.

关键词： Hypertension Recurrent stroke Antihypertensive medications

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Successful embolization of an intrahepatic portosystemic shunt using balloon-occluded retrograde transvenous obliteration:A case report

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World Journal of Clinical Cases 2022年第6期10卷 2023-2029页

作者： Hidemasa Saito Satoru Murata Fumie Sugihara Tatsuo Ueda Daisuke Yasui Izumi miki Hiromitsu Hayashi Shin-Ichiro Kumita Department of Radiology Nippon Medical SchoolTokyo 113-8602Japan Center for Interventional Radiology Teikyo University Chiba Medical CenterChiba 299-0011Japan

BACKGROUND A congenital intrahepatic portosystemic shunt(IPSVS)is a rare vascular abnormality that is characterized by an anomalous intrahepatic venous tract that connects the intrahepatic portal vein with the hepatic venous *** encephalopathy is an indication for IPSVS embolization,which is technically challenging because rapid blood flow through shunts can induce the migration of embolization material to systemic *** case report discusses the efficacy of percutaneous balloon-occluded retrograde transvenous obliteration for treating patients with *** SUMMARY A 75-year-old woman presented with a six-month history of repeated hepatic encephalopathy due to an IPSVS without liver *** successfully embolized the IPSVS using percutaneous balloon-occluded retrograde transvenous obliteration with interlocking detachable *** the procedure,the patient exhibited no symptoms of hepatic encephalopathy for 14 *** Balloon-occluded retrograde transvenous obliteration with detachable coils can be effective for the endovascular treatment of an IPSVS.

关键词： Hepatic veins Portal vein Hepatic encephalopathy Endovascular procedures Embolization Therapeutic Case report

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