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World Journal of Gastroenterology 2024年第8期30卷 811-816页

作者： mike de.jong Foke van delft Christine Roozen Erwin-Jan van Geenen Tanya Bisseling Peter Siersema Marco Bruno department of Gastroenterology and Hepatology Radboud University Medical CenterNijmegen 6525 GANetherlands department of Gastroenterology and Hepatology Erasmus University Medical CenterRotterdam 3015 GDNetherlands

Endoscopic ultrasound(EUS)with fine needle aspiration or fine needle biopsy is the gold standard for sampling tissue to diagnose pancreatic cancer and auto-immune pancreatitis or to analyze cyst *** most common reported adverse event of fine needle aspiration and/or fine needle biopsy is acute pancreatitis,which is likely induced by the same pathophysiological mechanisms as after en-doscopic retrograde cholangiopancreatography(ERCP).According to the current European Society of Gastrointestinal Endoscopy guideline,nonsteroidal anti-inflammatory drugs are administered prior to ERCP as a scientifically proven treatment to reduce post-ERCP pancreatitis incidence rate.A single suppository of diclofenac or indomethacin prior to EUS guided tissue acquisition(TA)is harm-less in healthy *** it is associated with low costs and,most important,may prevent a dreadsome complication,we strongly recommend the adminis-tration of 100 mg diclofenac rectally prior to *** will explain this recom-mendation in more detail in this review as well as the risk and pathophysiology of post-EUS TA pancreatitis.

关键词： Pancreatitis Endoscopic ultrasound Tissue acquisition Nonsteroidal antiinflammatory drugs Pancreatic cancer

Al-20%Cu多晶粒竞争生长的原位观测及汇聚型枝晶淘汰模型构建

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Transactions of Nonferrous Metals Society of China 2024年第7期34卷 2095-2107页

作者：李发国周莲谢玉张佼 mike DODGE 尹付成孙宝德湘潭大学材料科学与工程学院湖南省材料设计与制备技术重点实验室湘潭411105 宝山钢铁有限公司中央研究院上海201900 上海交通大学材料科学与工程学院上海200240 TWI Ltd Granta ParkGreat AbingtonCambridge CB216ALUK

采用同步辐射成像技术研究Al-20%Cu(质量分数)亚共晶合金的晶粒竞争生长动力学,并建立与实验结果相一致的数学模型。结果表明,对于发散型竞争生长,遵循“正常淘汰”规则。对于汇聚型竞争生长,成分过冷的作用加速非择优取向晶粒中一次枝... 详细信息

采用同步辐射成像技术研究Al-20%Cu(质量分数)亚共晶合金的晶粒竞争生长动力学,并建立与实验结果相一致的数学模型。结果表明,对于发散型竞争生长,遵循“正常淘汰”规则。对于汇聚型竞争生长,成分过冷的作用加速非择优取向晶粒中一次枝晶臂的生长速度,导致非择优取向枝晶出现“异常淘汰”现象,淘汰择优取向枝晶。探讨汇聚型竞争生长的“正常淘汰”与“异常淘汰”之间的临界条件,建立枝晶生长速率、枝晶臂间距和枝晶倾斜角之间的数学关系,又称“二次枝晶臂阻挡模型”,可以快速预测晶界位相和淘汰类型。

关键词：竞争生长同步辐射成像定向凝固数学模型 Al-Cu合金

Stability analysis of a deterministic model of Zika/dengue co-circulation

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International Journal of Biomathematics 2019年第4期12卷 215-253页

作者： mike Binder Sergei S.Pilyugin department of Mathematics University of FloridaUSA

We consider a deterministic model of Zika and dengue viruses co-circulating in a human population. We study the system of differential equations modeling the dynamics of the diseases that can either be transmitted directly (host-to-host) or indirectly (host-vectorhost).We use an SIR model for hosts and an SI model for vectors in the homogeneous populations. The stability of the model has been analyzed both qualitatively and quantitatively.

关键词： Zika dengue secondary infection

Neoarchean and Rhyacian TTG-Sanukitoid suites in the southern S?o Francisco Paleocontinent,Brazil:Evidence for diachronous change towards modern tectonics

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Geoscience Frontiers 2020年第5期11卷 1763-1787页

作者： Henrique Bruno Vitalino Elizeu Monica Heilbron Claudio de Morisson Valeriano Rob Strachan mike Fowler Samuel Bersan Hugo Moreira Ivo Dussin Luiz Guilherme do Eirado Silva Miguel Tupinamba Julio Almeida Carla Neto Craig Storey Universidade Do Estado Do Rio de Janeiro Faculdade de GeologiaTektosGrupo de Pesquisa Em GeotectonicaRua Sao Francisco Xavier 524MaracanaRio de JaneiroBrazil University of Portsmouth School of Earth and Environmental SciencesBurnaby BuildingBurnaby RoadPortsmouthUK Universit€at Salzburg Department of Geography and GeologyKapitelgasse4-65020SalzburgAustria Universidade Federal de Ouro Preto Departamento de GeologiaCampus Morro Do CruzeiroOuro PretoMGBrazil Laboratorio de Geocronologia e Isotopos Radiog^enicos Universidade Do Estado Do Rio de JaneiroRua Sao Francisco Xavier 524MaracanaRio de JaneiroBrazil

The southern portion of the Sao Francisco Palaeocontinent in Brazil is denoted by Archean nuclei and Paleoproterozoic magmatic arcs that were amalgamated during Siderian to Orosirian orogenic processes(ca.2.4-2.1 Ga).New isotopic U-Pb in zircon and Sm-Nd whole rock combined with major and trace element composition analyses constrain the crystallization history of the Neoarchean Piedade block(at ca.2.6 Ga)and the Paleoproterozoic Mantiqueira Complex(ca.2.1-1.9 Ga).These therefore display quite different magmatic histories prior to their amalgamation at ca.2.05 ***-Nd and Rb-Sr isotopes imply a mixed mantle-crustal origin for the samples in both units.A complete Palaeoproterozoic orogenic cycle,from subduction to collision and collapse,is recorded in the Piedade Block and the Mantiqueira *** to Orosirian subduction processes(ca.2.2-2.1 Ga)led to the generation of coeval(ca.2.16 Ga)TTG suites and sanukitoids,followed by late(2.10-2.02 Ga)high-K granitoids that mark the collisional *** collisional accretion of the Mantiqueira Complex against the Piedade Block at 2.08-2.04 Ga is also recorded by granulite facies metamorphism in the latter terrane,along the Ponte Nova suture *** collisional stage was closely followed by the emplacement of within-plate tholeiites at ca.2.04 Ga and by alkaline rocks(syenites and enriched basic rocks)at ca.1.98 Ga,marking the transition to an extensional tectonic *** discovery of two episodes of TTG and sanukitoid magmatism,one during the Neoarchean in the Piedade Complex and another during the Rhyacian in the Mantiqueira Complex,indicates that the onset of subduction-related melting of metasomatized mantle was not restricted to Neoarchean times,as generally believed,but persisted much later into the Paleoproterozoic.

关键词： Geodynamics High Ba–Sr granitoids Diachronous TTG-Sanukitoid transition Paleoproterozoic Mantiqueira complex

An Adaptive ANOVA-Based Data-Driven Stochastic Method for Elliptic Pdes with Random Coefficient

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Communications in Computational Physics 2014年第8期16卷 571-598页

作者： Zhiwen Zhang Xin Hu Thomas Y.Hou Guang Lin mike Yan Computing and Mathematical Sciences California Institute of TechnologyPasadenaCA 91125USA. Pacific Northwest National Laboratory RichlandWA 99352USA.

In this paper,we present an adaptive,analysis of variance(ANOVA)-based data-driven stochastic method(ANOVA-DSM)to study the stochastic partial differential equations(SPdes)in the multi-query *** new method integrates the advantages of both the adaptive ANOVA decomposition technique and the data-driven stochastic *** handle high-dimensional stochastic problems,we investigate the use of adaptive ANOVA decomposition in the stochastic space as an effective dimension-reduction *** improve the slow convergence of the generalized polynomial chaos(gPC)method or stochastic collocation(SC)method,we adopt the data-driven stochastic method(DSM)for speed *** essential ingredient of the DSM is to construct a set of stochastic basis under which the stochastic solutions enjoy a compact representation for a broad range of forcing functions and/or boundary *** ANOVA-DSM consists of offline and online *** the offline stage,the original high-dimensional stochastic problem is decomposed into a series of lowdimensional stochastic subproblems,according to the ANOVA decomposition ***,for each subproblem,a data-driven stochastic basis is computed using the Karhunen-Lo`eve expansion(KLE)and a two-level preconditioning optimization *** trial functions are used to enrich the stochastic basis and improve the *** the online stage,we solve each stochastic subproblem for any given forcing function by projecting the stochastic solution into the data-driven stochastic basis constructed *** our ANOVA-DSM framework,solving the original highdimensional stochastic problem is reduced to solving a series of ANOVA-decomposed stochastic subproblems using the *** adaptive ANOVA strategy is also provided to further reduce the number of the stochastic subproblems and speed up our *** demonstrate the accuracy and efficiency of our method,numerical examples are presented for one-and two-dimensional elliptic Pdes with rando

关键词： Analysis of variance stochastic partial differential equations data-driven methods Karhunen-Loeve expansion uncertainty quantification model reduction.

Evolution of Siderian juvenile crust to Rhyacian high Ba-Sr magmatism in the Mineiro Belt, southern S?o Francisco Craton

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Geoscience Frontiers 2018年第4期9卷 977-995页

作者： Hugo Moreira Luís Seixas Craig Storey mike Fowler Stephanie Lasalle Ross Stevenson Cristiano Lana School of Earth and Environmental Sciences University of Portsmouth Burnaby Building Bumaby Road Portsmouth POI 3QL UK departamento de Geologia Escola de Minas Universidade Federal de Ouro Preto Ouro Preto MG 35400-000 Brazil GEOTOP Universite du Quebec a Montreal RO. Box 8888 Station Centre Ville Montreal Quebec H3C 3P8 Canada

Plutonic rocks from the Mineiro Belt, Brazil record a delayed onset of the transition from TTG to sanukitoid-type magmatism（high Ba-Sr）, starting during the Siderian magmatic lull when little juvenile magma was added to the continental crust. Rocks mostly belong to the calc-alkaline series, meta-to peraluminous and originally ＂Ⅰ-type＂,meaning that oxidized magmas were formed by partial melting of subducted material. The temporal distribution and apparent secular changes of the magmas are consistent with the onset of subduction-driven plate tectonics due to an increase of the subduction angle and opening of the mantle wedge. New isotopic analyses（Sm-Nd whole rock and Lu-Hf in zircon）corroborate the restricted juvenile nature of the Mineiro Belt and confirm the genetic link between the Lagoa Dourada Suite,a rare ca. 2350 Ma high-Al tonalite-trondhjemite magmatic event, and the sanukitoid-type ca. 2130 Ma Alto Maranhao Suite. U-Pb dating of zircon and titanite constrain the crystallisation history of plutonic bodies; coupled with major and trace element analyses of the host rocks, they distinguish evolutionary trends in the Mineiro Belt. Several plutons in the region have ages close to 2130 Ma but are distinguished by the lower concentration of compatible elements in the juvenile high Ba-Sr suite.

关键词： Sao Francisco Craton Magmatic lull TTG-Sanukitoid transition Zircon U-Pb-Hf Titanite U-Pb Whole rock Nd isotopes

LATHYROIdeS, Encoding a WUSCHEL-Related Homeoboxl Transcription Factor, Controls Organ Lateral Growth, and Regulates Tendril and Dorsal Petal Identities in Garden Pea （Pisum sativum L.）

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Molecular Plant 2012年第6期5卷 1333-1345页

作者： Li-Li Zhuang mike Ambrose Catherine Rameau Lin Weng Jun Yang Xiao-He Hu Da Luo Xin Li School of Life Science and Biotechnology Shanghai Jiao Tong UniversityShanghai 200240China department of Crop Genetics John Innes CentreColneyNorwich NR47UHUK Station de Genetique et d'Amelioration des Plantes Institut J.P.BourginUR 254 INRAVersaillesFrance National Key Laboratory of Plant Molecular Genetics Institute of Plant Physiology and EcologyShanghai Institutes for Biological SciencesChineseAcademy of SciencesShanghai 200032China State Key Laboratory of Biocontrol School of Life SciencesSun Yat-Sen University135 West Xin-gang RoadGuangzhou 510275China

During organ development, many key regulators have been identified in plant genomes, which play a conserved role among plant species to control the organ identities and/or determine the organ size and shape. It is intriguing whether these key regulators can acquire diverse function and be integrated into different molecular pathways among different species, giving rise to the immense diversity of organ forms in nature. In this study, we have characterized and cloned LATHYROIdeS （LATH）, a classical locus in pea, whose mutation displays pleiotropic alteration of lateral growth of organs and predominant effects on tendril and dorsal petal development. LATH encodes a WUSCHEL-related home- oboxl （WOX1） transcription factor, which has a conserved function in determining organ lateral growth among different plant species. Furthermore, we showed that LATH regulated the expression level of TENDRIL-LESS （TL）, a key factor in the control of tendril development in compound leaf, and LATH genetically interacted with LOBED STANDARD （LST）, a floral dorsal factor, to affect the dorsal petal identity. Thus, LATH plays multiple roles during organ development in pea： it maintains a conserved function controlling organ lateral outgrowth, and modulates organ identities in compound leaf and zygomorphic flower development, respectively. Our data indicated that a key regulator can play important roles in different aspects of organ development and dedicate to the complexity of the molecular mechanism in the control of organ development so as to create distinct organ forms in different species.

关键词： pea LATH LST TL lateral growth organ identity.

Efficiency of soil-applied ^(67)Zn-enriched fertiliser across three consecutive crops

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Pedosphere 2021年第4期31卷 531-537页

作者： Edson M.MATTIELLO Eduardo L.CANCELLIER Rodrigo C.DA SILVA Fien deGRYSE Roslyn BAIRD mike J.MCLAUGHLIN department of Soil Science Universidade Federal de ViçosaViçosaMinas Gerais(Brazil) department of Soil Science Universidade Federal de LavrasMinas Gerais(Brazil) The University of Adelaide School of AgricultureFood and WineFertiliser Technology Research CentrePMB 1Waite CampusGlen Osmond SA 5064(Australia)

A very small amount of applied zinc(Zn) is taken up by crops, resulting in low recovery by plants. Adding elemental sulphur to zinc oxide(ZnO) fertiliser could improve Zn solubilisation and exert a higher residual effect on crops than soluble Zn sources. We produced an isotopically labelled Zn-elemental sulphur fertiliser and evaluated its performance in comparison to traditional Zn sources during sequential crop cultivation. Three ^(67)Zn-labelled fertilisers,ZnO, zinc sulphate(ZnSO_(4)), and ZnO co-granulated with elemental sulphur(ZnOS^(0)), were soil applied, and their contributions to the uptake of Zn by three consecutive crops, wheat, ryegrass, and corn, were assessed in a 294-d pot experiment. The contributions of Zn fertilisers followed the order: ZnSO_(4) > ZnO= ZnOS^(0). The relative contributions of Zn fertilisers were lower in the first crop than in the subsequent crops. The overall recovery of applied Zn by the three crops was higher for ZnSO_(4) than for ZnO and ZnOS^(0), reaching 1.56%, 0.45%, and 0.33% of the applied Zn, respectively. Zinc recovery by plants was very low, regardless of the source of Zn. Adding elemental sulphur to ZnO did not increase its effectiveness up to 294 d after application. Fertiliser contribution was higher for the subsequent crops than for the initial crop, indicating the importance of assessing the residual effects of Zn fertilisers.

关键词： agronomic biofortification elemental sulphur fertilizer residual effect plant uptake Zn bioavailability Zn fertilization Zn source

Genetic Analysis of ele Mutants and Comparative Mapping of ele1 Locus in the Control of Organ Internal Asymmetry in Garden Pea

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Journal of Integrative Plant Biology 2010年第6期52卷 528-535页

作者： Xin Li Li-Li Zhuang mike Ambrose M. Phil. Catherine Rameau Xiao-He Hu Jun Yana Da Luo School of Life Science and Biotechnology Shanghai JiaoTong University Shanghai 200030 China department of Crop Genetics John Innes Centre Colney Norwich NR4 7UH United Kingdom Station de Genetique et d'Amelioration des Plantes Institut J.P. Bourgin UR 254 INRA Versailles France National Key Laboratory of Plant Molecular Genetics Institute of Plant Physiology and Ecology Shanghai Institutes for Biologica Sciences the Chinese Academy of Sciences Shanghai 200032 China

Previous study has shown that during zygomorphic development in garden pea （Pisum sativum L.）, the organ internal （IN） asymmetry of lateral and ventral petals was regulated by a genetic locus, SYMMETRIC PETAL 1 （SYP1）, while the dorsoventral （DV） asymmetry was determined by two CYC-like TCP genes or the PsCYC genes, KEELED WINGS （K） and LOBED STANDARD 1 （LST1）. In this study, two novel loci, ELEPHANT EAR-LIKE LEAF 1 （ELE1） and ELE2 were characterized. These mutants exhibit a similar defect of IN asymmetry as syp1 in lateral and ventral petals, but also display pleiotropic effects of enlarged organ size. Genetic analysis showed that ELE1 and ELE2 were involved in same genetic pathway and the enlarged size of petals but not compound leaves in e/e2 was suppressed by introducing k and Ist1, indicating that the enlargement of dorsal petal in e/e2 requires the activities of K and LST1. An experimental framework of comparative genomic mapping approach was set up to map and clone LjELE1 locus in Lotus japonicus. Cloning the ELE1 gene will shed light on the underlying molecular mechanism during zygomorphic development and further provide the molecular basis for genetic improvement on legume crops.

关键词： Viverridae Genetics Organizations Corolla Loci

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别让你的销售团队掉队

商学院 2012年第6期 J0019-J0022页

作者： mike Moriarty Remko de Bruijn 科尔尼公司

再好的设计和产品，销售是让它们实现价值的最根本方式。在过去的15年，很多企业的销售工作都处于自动导航状态。但是在大多数企业，销售岗位恰恰比其他任何一个职能岗位的变化都要大。今天的销售已不同往昔，它变得更加复杂，更加技术... 详细信息

再好的设计和产品，销售是让它们实现价值的最根本方式。在过去的15年，很多企业的销售工作都处于自动导航状态。但是在大多数企业，销售岗位恰恰比其他任何一个职能岗位的变化都要大。今天的销售已不同往昔，它变得更加复杂，更加技术化，更具策略性而不再以常规订单为主，并且要求对客户需求有更加深刻的把握。企业老的销售团队是否在紧跟这些新趋势呢？为追求竞争优势，企业管理者改进采购方法，调整制造及运营网点，重新思考新的产品管线，精简行政职能并完善营销信息。但是，很少有人把枪口对准销售。他们担心，插手销售没准会破坏它的魔力。在几年之前，这种担忧可能是有道理的，但今天却并非如此。

关键词：企业管理者销售团队企业领导产品