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Difficulty of falling asleep and non-high-density lipoprotein cholesterol level among Canadian older adults:a cross-sectional analysis of the Canadian Longitudinal Study for Aging baseline data

引用

Journal of Geriatric Cardiology 2021年第8期18卷 597-608页

作者： Jian LIU Surim Son mike giancaterino Miya Narushima Department of Health Sciences Brock UniversitySt.CatharinesOntarioCanada

OBJECTIVE To examine whether difficulty of falling asleep(DoFA)is associated with non-high-density lipoprotein cholesterol(non-HDL-C)level among Canadian older *** 26,954 individuals aged 45-85 years from the baseline data of the Canadian Longitudinal Study for Aging were in-cluded in this *** was categorized into five groups by answer to the question“Over the last month,how often did it take you more than 30 min to fall asleep?”Response options are“Never,<1 time/week,1−2 times/week,3−5 times/week,or 6−7 times/week”.Non-HDL-C,the difference of total cholesterol and HDL-C,were categorized into five categories based on these cut-offs(<2.6 mmol/L,2.6−3.7 mmol/L,3.7−4.8 mmol/L,4.8−5.7 mmol/L,and≥5.7 mmol/L).Ordinal logistic regression(logit link)continuation ratio models were used to estimate the odds of higher non-HDL-C levels for DoFA *** means of non-HDL-C by DoFA status were estimated by general linear *** analyses were sex separately using analytic weights to en-sure *** The proportions of DoFA in five categories were 41.6%,25.7%,13.6%,9.4%,9.7%for females and 52.9%,24.9%,10.5%,6.1%,5.6%for males,*** adjustment of demographical and other covariates(such as depression,comorbidity,sleeping hour,etc.)compared to those who reported never having DoFA,the ORs(95%CIs)of higher levels of non-HDL-C for those whose DoFA status in<1 time/week,1−2 times/week,3−5 times/week,and 6−7 times/week were 1.12(1.05−1.21),1.09(0.99−1.18),1.20(1.09−1.33),1.29(1.17−1.43)in females and 1.05(0.98−1.13),0.95(0.87−1.05),1.21(1.08−1.37),0.97(0.85−1.09)in males,*** adjusted means of non-HDL-C among the five DoFA status were 3.68 mmol/L,3.73 mmol/L,3.74 mmol/L,3.82 mmol/L,3.84 mmol/L for females and 3.54 mmol/L,3.58 mmol/L,3.51 mmol/L,3.69 mmol/L,3.54 mmol/L for males,*** The results of this study have identified a risk association pattern between DoFA status and non-HDL-C levels in females

关键词： cholesterol sectional Canadian

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