检索结果-南通市图书馆

Patterns of Recurrence and Their Significance in Patients with Endometrial Carcinoma<br>—For Improved Follow-Up after Initial Treatment<br>

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Surgical Science 2013年第2期4卷 154-159页

作者： Fumi Utsumi Hiroaki Kajiyama Kiyosumi Shibata Hiroko Mitsui Ryuichiro Sekiya mika Mizuno Shiro Suzuki Tomokazu Umezu Eiko Yamamoto Fumitaka Kikkawa Department of Obstetrics and Gynecology Nagoya University Graduate School of Medicine Nagoya Japan

Objectives: The aim of this study was to identify the patterns of recurrence and their significance in patients with endometrial carcinoma (EMCA). Patients and Methods: After a search of the medical records from single institutions, a total of 49 patients with relapsed endometrial carcinoma were retrospectively evaluated. Various clinical information was examined, including the site of recurrence, detection procedure, and presence or absence of any symptom at the time of recurrence. Furthermore, the postrecurrence survival analysis was based on the Kaplan-Meier method. Results: The median follow-up period of all patients was 39.4 months (5.8 - 293.1). In all, twenty-five (51.0%) patients experienced recurrence within 12 months after the final treatment. At the time of recurrence, 15 (30.6%) and 34 (69.4%) patients were symptomatic and asymptomatic, respectively. Among the 34 asymptomatic patients, recurrence was detected by CT scan in 14 (28.6%), tumor markers alone in 14 (28.6%), and pelvic examination/ultrasound scan in 5 (10.2%). There was no relapsed case detected by vaginal vault cytology alone. The 5-year postrecurrence survival rates in symptomatic and asymptomatic patients were 57.5 and 36.6 months, respectively (P = 0.2973). After recurrence, 12 patients underwent debulking surgery, and 37 received salvage chemotherapy or radiotherapy. The postrecurrence survival of patients receiving surgery did not differ from that of those with chemotherapy/radiotherapy (P = 0.9198). Conclusion: Although imaging studies and tumor marker measurement contributed to the early detection of recurrence, they did not necessarily improve the prognosis postrecurrence.

关键词： Endometrial Carcinoma Recurrence Site Postrecurrence Survival Symptomatic Vaginal Vault Cytology

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Improvement of Scalp Condition and Quality of Life through Proper Skin Care of Dry Scalp

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Journal of Cosmetics, Dermatological Sciences and Applications 2014年第4期4卷 284-292页

作者： mika Oshima Maiko Sogawa Hiroshi Matsunaka Yumi Murakami Yumiko Saya Takashi Sugita Yoshihiro Matsudate Nozomi Fukui Kazutoshi Murao Yoshiaki Kubo Department of Dermatology Institute of Health Biosciences The University of Tokushima Graduate School Tokushima Japan Tokiwa Pharmaceutical Co. Ltd. Tokyo Japan Department of Microbiology Meiji Pharmaceutical University Tokyo Japan

Introduction: Appropriate skin care for dry scalp includes treatment for dandruff and itchiness. However, little is known about the appropriate washing methods for subjects with dry scalp. Me- thods: A scalp moisturizing lotion was used for 8 weeks on 30 outpatients at the Tokushima University Hospital who had dry scalp. All subjects were given the same hair shampoo/conditioner and instructions on how to wash their hair. Scalp symptoms were observed before and after the testing period. Indigenous bacteria were collected from the scalp for quantitative assessment. A survey was conducted to assess the quality of life (QOL). Results: All scalp condition items (dryness, scales and desquamation, itchiness, excoriation, and erythema) improved significantly after the testing period;the levels of Malassezia and bacterial colonization also decreased significantly. The QOL evaluation indicated significant improvements in “symptoms”, “emotions”, and “global” measures. A correlation was found between the extent of dryness at the start of the test and the level of Malassezia colonization, as well as QOL scores. Conclusion: Using a scalp moisturizing lo- tion, washing hair with a shampoo and conditioner that cause low irritation levels, and using a hair washing method that avoids irritation led to improvement in scalp condition, QOL, and pa- tient satisfaction.

关键词： Atopic Dermatitis Seborrheic Dermatitis Moisturizer Malassezia Bacteria qPCR

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Inhibition of the Oversensing of Cardiac Pacemakers in Chest CT

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Open Journal of Medical Imaging 2012年第4期2卷 119-124页

作者： Norihiko Akiba Masashi Takeda Giichiro Nakaya Osamu Nakamura mika Tsuboi Joel Matsumoto Kyoichi Ito Yasuo Okuyama Morio Shimada Kohki Yoshikawa Department of Clinical Engineering National Hospital Organization Tokyo Medical Center Tokyo Japan Department of Radiological Technology Nihon Institute of Medical Science Moroyama Japan Department of Radiology Japanese RedCross Medical CenterTokyo Japan Department of Radiology National Hospital Organization Tokyo Medical Center Tokyo Japan Graduate Division of Medical Health Sciences in Graduate School of Komazawa University Tokyo Japan Toshiba Medical Systems Corporation Tokyo Japan

Objectives: The purpose of this study is to identify how to manage oversensing of pacemakers in chest CT. Methods: Four different models of pacemakers were examined to select the pacemaker generating oversensing. To the pacemaker with oversensing, intermittent switching X-ray was exposed using ECG-gated CT helical scan system at prospective CTA mode. IVY Model was used to synchronize the ECG. Only during in the alert period that is non-refractory and sensing is available, intermittent switching X-ray (300 msec/sec) was exposed in chest CT. For comparison, the same intermittent switching X-ray (300 msec/sec) was exposed in the refractory period when sensing was not available. Results: Oversensing was detected only in one of the four pacemakers tested. In this pacemaker, oversensing was generated by exposure of the intermittent switching X-ray in the alert (non-refractory) period, but oversensing was not observed in the refractory period. Conclusion: A pacemaker has alert and refractory periods. Oversensing of a pacemaker was found to be inhibited by selective ECG-synchronized exposure in the refractory period. Since all pacemakers have the refractory period, the results of this study can be widely applied to the patients with pacemakers in chest CT, and their chest CT can be operated safely.

关键词： Cardiac Pacemaker Refractory Period Oversensing Computed Tomography Chest CT

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赫尔辛基艺术大学

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城市环境设计 2023年第5期145卷 210-221页

作者： Tuomas Uusheimo Marc Goodwin Asmo Jaaksi mika Huisman JKMM

赫尔辛基艺术大学为学生和教职工提供了一处可以在其上创作的独特教学空间,新设计通过对原有建筑进行充满想象力的改造,向索奈宁(S?rn?inen)地区的历史致敬。这个独特的后工业化社区如今已充满着年轻的活力。创造者空间改造后的美术学...

赫尔辛基艺术大学为学生和教职工提供了一处可以在其上创作的独特教学空间,新设计通过对原有建筑进行充满想象力的改造,向索奈宁(S?rn?inen)地区的历史致敬。这个独特的后工业化社区如今已充满着年轻的活力。创造者空间改造后的美术学院为美术、灯光、声音设计以及表演艺术的学生提供了宽敞、有力、

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优衣库:把服饰基本品变成超级摇钱树

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商学院 2012年第6期 42-56页

作者：柳井正 mika K. 马新莉日本迅销集团

中国本土的快时尚企业在艰难中行进。近日，美邦服饰关闭了2000平方米的上海旗舰店，舶来的大店模式备受质疑，而年销售额已突破30亿元的凡客诚品，仍在亏损巨大的泥沼中苦苦挣扎。与之相比，无论在定位清晰度、赚钱能力、人才培养还是... 详细信息

中国本土的快时尚企业在艰难中行进。近日，美邦服饰关闭了2000平方米的上海旗舰店，舶来的大店模式备受质疑，而年销售额已突破30亿元的凡客诚品，仍在亏损巨大的泥沼中苦苦挣扎。与之相比，无论在定位清晰度、赚钱能力、人才培养还是店铺经营模式上，日本的优衣库都有资格来上一课。一个日本本土的服饰企业，缘何能将最不起眼的基本品，在全世界卖成老少通吃的畅销货？很多人对优衣库的印象是，这是一家生产基本款休闲服并以低价销售的企业，但是与低价销售相比，优衣库认为自己考虑更多的是“制作高品质的好服装，让所有人都买得起”。他们通过出色的供应链管理、直达人心的销售战略、店铺主导的扁平组织，创造出一个飞速发展的世界级服饰帝国，并且建立起日本新一代企业积极、灵活、大胆进取的形象。在一定程度上说，优衣库的实践也是“柳井正主义”的成功。这位在外人眼中不讲情面、强势坚毅的创始人，在整整40年时间里，九败才有一胜，期间还经历了退休和复出的“二次创业”，而横在他与他的终极理想之间的，也还有诸多障碍需要克服。以他和他的优衣库做中国企业的参照系，真是再合适不过。

关键词：服饰企业摇钱树日本本土 “二次创业” 低价销售中国企业供应链管理年销售额

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弧之美

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建筑实践 2015年第1期 20-25页

作者：杨一石 Tuomas Uusheimo mika Huisman

坐落在芬兰赫尔辛基市中心区历史街区的赫尔辛基大学主图书馆.简直就是一栋”弧与拱的建筑”。Anttinen Oiva Architects的建筑师说,城市景观是这栋图书馆建筑设计的出发点。他们认为,作为一栋特别的公共建筑.应该要主动从材料.设计和... 详细信息

坐落在芬兰赫尔辛基市中心区历史街区的赫尔辛基大学主图书馆.简直就是一栋”弧与拱的建筑”。Anttinen Oiva Architects的建筑师说,城市景观是这栋图书馆建筑设计的出发点。他们认为,作为一栋特别的公共建筑.应该要主动从材料.设计和高度等方面融入周围的环境。由于之前位于这栋建筑所在位置的旧的混凝土结构已经不堪重负.因此建设新的图书馆建筑时.便在原先的地下室上面建了一个经过了加固的混凝土框架。

关键词：建筑师几何式室内空间赫尔辛基大学内部空间外立面

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赫尔辛基艺术大学

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当代建筑 2022年第7期 120-126页

作者：无 Marc Goodwin(摄影) mika Huisman(摄影) Tuomas Uusheimo(摄影) 芬兰JKMM建筑师事务所不详

1创客空间该建筑是由芬兰JKMM建筑师事务所设计而成的,其独创性在于为美术、灯光、音响设计和表演艺术设计专业的学生提供宽敞、有力、光线充足、定义清晰的空间。这座公共的、可修改的建筑将具有多种用途,其可以创造和体验各种各样的... 详细信息

1创客空间该建筑是由芬兰JKMM建筑师事务所设计而成的,其独创性在于为美术、灯光、音响设计和表演艺术设计专业的学生提供宽敞、有力、光线充足、定义清晰的空间。这座公共的、可修改的建筑将具有多种用途,其可以创造和体验各种各样的艺术形式、多样的媒介、不同规模的作品。因此,该建筑的设计理念是为了促进且不限制创造性。

关键词：创客空间建筑师事务所光线充足音响设计赫尔辛基艺术设计专业创造性设计理念

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High REDOX RESPONSIVE TRANSCRIPTION FACTOR1 Levels Result in Accumulation of Reactive Oxygen Species in Arabidopsis thaliana Shoots and Roots

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Molecular Plant 2015年第8期8卷 1253-1273页

作者： Mitsuhiro Matsuo Joy MichalJohnson Ayaka Hieno Mutsutomo Tokizawa mika Nomoto Yasuomi Tada Rinesh Godfrey Junichi Obokata Irena Sherameti Yoshiharu Y. Yamamoto~l Frank-D. Boehmer Ralf Oelmuller Institute of Plant Physiology Friedrich-Schiller University Jena Dornburger StraSe 159 07743 Jena Germany Graduate School of Life and Environmental Sciences Kyoto Prefectural University 1-5 Hangi-cho Shimogamo Sakyo-ku Kyoto 606-8522 Japan Faculty of Applied Biological Sciences Gifu University Yanagido 1-1 Gifu City 501-1193 Japan Center for Gene Research Nagoya University Furo-cho Chikusa-ku Nagoya 464-8601 Japan Institute of Molecular Cell Biology Center for Molecular Biomedicine Jena University Hospital 00743 Jena Germany Molecular Cardiology Department of Cardiovascular Medicine University Hospital M0nster 48149 M0nster Germany These authors contributed equally to this article.

Redox Responsive Transcription Factor1 （RRTF1） in Arabidopsis is rapidly and transiently upregulated by H202, as well as biotic- and abiotic-induced redox signals. RRTF1 is highly conserved in angio- sperms, but its physiological role remains elusive. Here we show that inactivation of RRTF1 restricts and overexpression promotes reactive oxygen species （ROS） accumulation in response to stress. Transgenic lines overexpressing RRTF1 are impaired in root and shoot development, light sensitive, and susceptible to Alternaria brassicae infection. These symptoms are diminished by the beneficial root endophyte Piriformospora indica, which reduces ROS accumulation locally in roots and systemi- cally in shoots, and by antioxidants and ROS inhibitors that scavenge ROS. More than 800 genes were detected in mature leaves and seedlings of transgenic lines overexpressing RRTF1; ∽40% of them have stress-, redox-, ROS-regulated-, ROS-scavenging-, defense-, cell death- and related functions. Bioinformatic analyses and in vitro DNA binding assays demonstrate that RRTF1 binds to GCC-box-like sequences in the promoter of RRTFl-responsive genes. Upregulation of RRTF1 by stress stimuli and H202 requires WRKY18/40/60. RRTF1 is co-regulated with the phylogenet- ically related RAP2.6, which contains a GCC-box-like sequence in its promoter, but transgenic lines overexpressing RAP2.6 do not accumulate higher ROS levels. RRTF1 also stimulates systemic ROS accumulation in distal non-stressed leaves. We conclude that the elevated levels of the highly conserved RRTF1 induce ROS accumulation in response to ROS and ROS-producing abiotic and biotic stress signals.

关键词： abiotic and biotic stress reactive oxygen species H202 REDOX RESPONSIVE TRANSCRIPTIONFACTOR1 RAP2.6 RRTF1 promoter binding sites

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Nursing Practice on Post-Operative Wound Care in Surgical Wards at Muhimbili National Hospital, Dar-es-Salaam, Tanzania

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Open Journal of Nursing 2019年第8期9卷 870-890页

作者： Adela A. Mwakanyamale Anna Mary A. Mukaja Mathew D. Ndomondo Joan P. Zenas Ambroce M. Stephen Elizabeth Z. mika Department of Medical and Surgical Nursing Faculty of Nursing Hubert Kairuki Memorial University Dar-es-Salaam Tanzania Department of Fundamentals of Nursing and Basic Sciences Hubert Kairuki Memorial University Dar-es-Salaam Tanzania

Background: Postoperative wound healing has been a problem which causes high mortality in the developing world;postoperative wound has been reported to cause devastating consequences and a measurable mortality. There is a limited number of published studies in Tanzania investigating Nursing practice on post-operative wound care in surgical wards at Muhimbili National Hospital, Dar-es-Salaam, Tanzania. This study assesses nursing practice on postoperative wound care by nurses in surgical wards at Muhimbili National Hospital. Methods: A cross-sectional study of surgical nurses was carried out through the use of randomly selected surgical wards at Muhimbili National Hospital in Tanzania from September 2011 to July 2013. A multistage cluster sampling technique was used to obtain a suitable number of study participants. Data collection was done using a checklist from a convenient sample of 71 nurses in selected surgical wards. Results: The result indicates that a big number of the participants were female (76.5%) and those of the age group 25 to 34 years were 40.8%. Participants exceeding a half of the selected sample reported to have poor post-operative wound care practice (57.7%). In comparison, male participants scored higher, and had better practice than their female counterparts, however, there was no considerable difference in the scores (P = 0.803). During set-up and preparation phase, the washing of hands before starting and after the completion of procedure was taken into consideration by less than half of the participants (49.3%). All participants did not ensure the environment is clean and take into account the patient’s privacy through the use of screen or even closing the room. The report shows that nurses take into consideration putting on clean gloves during the removal of the old dressing (99%), the use of sterile gloves during wound dressing was taken into consideration by most of the nurses (63%). Good practice was noted in applying dressing solution as

关键词： Wound Post-Operative Care Wound Dressing Infection

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Renal Cell Carcinoma Associated with Xp11.2 Translocation/TFE3 Gene Fusion: A Case Report with Immunohistochemical and Cytological Features

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Open Journal of Pathology 2016年第1期6卷 19-25页

作者： Takuji Tanaka Kuniaki Hirai Fumimasa Etori Masashi Matsuyama Naoki Watanabe Hiromi Kondo Masayoshi Tamaki Tatsuya Yamashita Shiho Yasue mika Noda Kunihiro Shinoda Hisao Komeda Department of Diagnostic Pathology (DDP) & Research Center of Diagnostic Pathology (RC-DiP) Gifu Municipal Hospital Gifu Japan Department of Radiology Ehime University Graduate School of Medicine Ehime Japan Department of Urology Gifu Municipal Hospital Gifu Japan Department of Pediatrics Gifu Municipal Hospital Gifu Japan

Gene fusions involving two of the MiT subfamily factors, such as TFE3, TFEB, TFC and MiTF, have been identified in renal cell carcinoma (RCC). Xp11.2 translocation RCC is a rare pediatric neoplasm that harbors gene fusions involving TFE3, which plays an important role in cell proliferation and survival. We herein present a case of RCC associated with Xp11.2 translocation/TFE3 gene fusion in a 14-year-old Japanese boy presenting gross hematuria and body weight loss. The tumor was characterized by histopathology, cytology and TFE3-immunohistochemistry/immunocytochemistry. Knowledge of distinctive morphological and immunostaining features of this tumor can help to accurately diagnose this rare subset of translocation associated RCC in routine pathological diagnostic procedures.

关键词： Renal Cell Carcinoma Xp11.2 Translocation TFE3 Cytology Immunohistochemistry Immunocytochemistry

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