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Unsedated transnasal small-caliber esophagogastroduoden oscopy in elderly and bedridden patients

World Journal of Gastroenterology 2009年第44期15卷 5586-5591页

作者： mika Yuki Yuji Amano Yoshinori Komazawa Hiroyuki Fukuhara Toshihiro Shizuku Shun Yamamoto Yoshikazu Kinoshita Division of Internal Medicine Izumo-City General Medical Center613 Nadabunn-choIzumo-shi Shimane 693-0003Japan Division of Endoscopy Shimane University Hospital89-1 Enya-choIzumo-shiShimane 693-8501Japan Division of Internal Medicine Unnan Municipal General Hospital96-1 Iida-choUnnan-shiShimane 699-1221Japan Second Department of Internal Medicine Shimane UniversitySchool of Medicine89-1 Enya-choIzumo-shiShimane 693-8501Japan

AIM： To evaluate the safety of unsedated transnasal small-caliber esophagogastroduodenoscopy （EGD） for elderly and critically ill bedridden patients. METHODS： One prospective randomized comparative study and one crossover comparative study between transnasal small-caliber EGD and transoral conventional EGD was done （Study 1）. For the comparative study, we enrolled 240 elderly patients aged 〉 65 years old. For the crossover analysis, we enrolled 30 bedridden patients with percutaneous endoscopic gastrostomy （PEG）（Study 2）, We evaluated cardiopulmonary effects by measuring arterial oxygen saturation （SpO2） and calculating the rate-pressure product （RPP）（pulse rate x systolic blood pressure/100） at baseline, 2 and 5 min after endoscopic intubation in Study 1. To assess the risk for endoscopy-related aspiration pneumonia during EGD, we also measured blood leukocyte counts and serum C-reactive protein （CRP） levels before and 3 d after EGD in Study 2. RESULTS： In Study 1, we observed significant decreases in SpO2 during conventional transoral EGD, but not during transnasal small-caliber EGD （0.24% vs -0.24% after 2 min, and 0.18% vs -0.29% after 5 min, P = 0.034, P = 0.044）. Significant differences of the RPP were not found between conventional transoral and transnasal small-caliber EGD. In Study 2, crossover analysis showed statistically significant increases of the RPP at 2 min after intubation and the end of endoscopy （26.8 and 34.6 vs 3.1 and 15.2, P = 0.044, P = 0.046）, and decreases of SpO2 （-0.8% vs -0.1%, P = 0.042） during EGD with transoral conventional in comparison with transnasal small-caliber endoscopy. Thus, for bedridden patients with PEG feeding, who were examined in the supine position, transoral conventional EGD more severely suppressed cardiopulmonary function than transnasal small-caliber EGD. There were also significant increases in the markers of inflammation, blood leukocyte counts and serum CRP values, in bedridden patients after transoral co

关键词： Aged Aspiration pneumonia Gastrointestina endoscopy Critical illness

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Relationship between Nonexercise Activity Thermogenesis and Calf Circumference in Older Women

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Open Journal of Therapy and Rehabilitation 2024年第3期12卷 213-223页

作者： Michio Wachi Takumi Jiroumaru mika Suzuki Shinichi Noguchi Ayako Satonaka Department of Physical Therapy Bukkyo University Kyoto City Japan Department of Physical Therapy Biwako Professional University of Rehabilitation Higashiomi City Japan Graduate School of Medicine Nagoya University Nagoya City Japan Faculty of Health and Medical Science Aichi Syukutoku University Nagakute City Japan

Purpose: Frailty is a state of declined vitality of the body and mind with age in which life functions are impaired. In addition, there is a difference in the susceptibility of older women to frailty compared with that of older men. Therefore, assessing and encouraging physical activity in older adults before they become frail is essential. We aimed to clarify the relationship between calf circumference and body composition and assess the potential association between calf circumference and physical activity indices in older women. Methods: This cross-sectional study included 18 healthy older adults (age 69.0 ± 5.7 years). The physical characteristics, calf circumference, body composition, calf muscle thickness, and physical activity questionnaire that included items on exercise-related activity thermogenesis (EAT) and nonexercise activity thermogenesis (NEAT) were assessed. The association between calf circumference and these additional measures was examined. Results: Positive and significant correlations were found between the calf circumference and body weight, body mass index (BMI), skeletal muscle mass, skeletal muscle mass index, calf muscle thickness, total questionnaire score, and NEAT score (r = 0.66 - 0.87). However, no significant correlations were observed between the calf circumference and EAT scores. Conclusion: Calf circumference in older women may reflect NEAT activity. Improving NEAT activity is an important health-promoting factor in older women.

关键词： Nonexercise Activity Thermogenesis Frailty Calf Circumference Older Women

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On-treatment predictions of success in peg-interferon/ribavirin treatment using a novel formula

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World Journal of Gastroenterology 2010年第1期16卷 89-97页

作者： Hidetsugu Saito Hirotoshi Ebinuma Keisuke Ojiro Kanji Wakabayashi mika Inoue Shinichiro Tada Toshifumi Hibi Department of Internal Medicine School of MedicineKeio University

AIM:To predict treatment success using only simple clinical data from peg-interferon plus ribavirin therapy for chronic hepatitis C. METHODS:We analyzed the clinical data of 176 patients with chronic hepatitis and hepatitis C virus genotype 1 who received 48 wk standard therapy, derived a predictive formula to assess a sustained virological response of the individual patient using a logistic regression model and confirmed the validity of this *** formula was constructed using data from the first 100 patients enrolled and validated using data from the remaining 76 patients. RESULTS:Sustained virological response was obtained in 83(47.2%)of the patients and we derived formulae to predict sustained virological response at pretreatment and weeks 4,12 and *** likelihood of sustained virological response could be predicted effectively bythe formulae at weeks 4,12 and 24(the area under the curve of the receiver operating characteristic:0.821, 0.802,and 0.891,respectively),but not at baseline (0.570).The formula at week 48 was also constructed and validation by test data achieved good prediction with 0.871 of the area under the curve of the receiver operating *** by this formula was always superior to that by viral kinetics. CONCLUSION:These results suggested that our formula combined with viral kinetics provides a clear direction of therapy for each patient and enables the best tailored treatment.

关键词： Logistic regression analysis Predictive formula Prolongation of the therapy Response-guided therapy Viral kinetics

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Industrial minerals and rocks, aggregates and natural stones in the Nordic countries

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Episodes 2008年第1期31卷 133-139页

作者： Kurt Johansson Rune B. Larsen Markku J. Lehtinen Lars Persson mika Raeisaenen Stig A. Schack Pedersen Paer Weihed Nils-Gunnar Wik Swedish Stone Industries Federation Industrigatan 6 SE-291 36 Kristianstad Sweden. NTNU NO-7491 Trondheim. Norway. Nordkalk Oyj Abp Poikkitie 1 FI-53500 Lappeenranta Finland. Geological Survey of Sweden SE-751 87 Uppsala Sweden. Geological Survey of Finland PO Box 96 FI-02151 Espoo Finland. Geological Survey of Denmark and Greenland Ф. Voldgade 10 DK-1350 Cph. Denmark. Division of Ore Geology and Applied Geophysics Lulea University of Technology SE-971 87 Lulea Sweden. Geological Survey of Sweden SE-223 50 Lund Sweden.

The Nordic countries, including Greenland, have a long tradition in mining. The industrial minerals sector is expanding in most Nordic countries and extensive development has taken place during the last few years. The main commodities mined are carbonate rocks, quartz, feldspar, apatite, olivine and talc. A number of diferent types of dimension stones are quarried in all countries. Rock aggregates are increasingly important, replacing sand and gravel aggregate as construction materials in some countries due to the need to protect ground water supplies.

关键词：工业矿产岩石集合体天然石材北欧地区

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运转平稳行星减速器的模块系统

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工程设计学报 2005年第6期12卷 379-380,383页

作者： Martin mika 毛谦德刘耀乙 Zeitlauf(时代)责任有限公司北京理工大学机械与车辆工程学院 100081 北京理工大学科学技术学院 100081

在2004年汉诺威博览会上,时代(Ze itlau f)公司首次展出了具有实际意义的行星减速器结构系列“Perfor-m ax”.该系列由于高运转平稳性、高功率密度和高寿命,在市场上脱颖而出.结构系列一直是按照模块系统建造的,从而明显地减少了必需的... 详细信息

在2004年汉诺威博览会上,时代(Ze itlau f)公司首次展出了具有实际意义的行星减速器结构系列“Perfor-m ax”.该系列由于高运转平稳性、高功率密度和高寿命,在市场上脱颖而出.结构系列一直是按照模块系统建造的,从而明显地减少了必需的组件数和加工步骤.

关键词：运转平稳性行星减速器模块系统汉诺威博览会高功率密度实际意义系统建造高寿命结构组件

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Involvement of mitochondrial swelling in cytochrome c release from mitochondria treated with calcium and Alloxan

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Journal of Biophysical Chemistry 2011年第1期2卷 10-18页

作者： Takuya Ichimura mika Ito Kiyoshi Takahashi Kyohei Oyama Koichi Sakurai 不详

An early event in the induction of apoptosis is cytochrome c (Cyt c) release from mitochondria. We investigated the involvement of mitochonrial permeability transition (MPT) and mitochondrial swelling in Cyt c release from mitochondria treated with alloxan and/or calcium (Ca2+). When mitochondria were treated with a high concentration of Ca2+. alone or Ca2+. with alloxan (alloxan-Ca2+), the MPT was accompanied by mitochondrial swelling and the release of Cyt c. Cyclosporin A prevented the induction of MPT but only slightly decreased the release of Cyt c. High molecular weight polyethylene glycol almost completely inhibited MPT-dependent osmotic mitochondrial swelling and Cyt c release. However, MPT-independent mitochondrial swelling and Cyt c release induced by exogenous K+. were inhibited by the high molecular weight polyethylene glycol. Ruthenium red strongly decreased the amount of Cyt c released. These results suggest that mitochondrial swelling but not MPT is necessary for Cyt c release induced by Ca2+ alone or alloxan and Ca2+.

关键词： Mitochondrial Swelling Cytochrome C Release Calcium Alloxan Mitochondrial Permeability Transition

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Improving Winter Traction and Fuel Economy of Car Tires Using Naphthenic Tire Oils

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Journal of Traffic and Transportation Engineering 2018年第1期6卷 35-41页

作者： mika Lahtinen Kamyar Alavi Patrik Salomonsson Markus Hoffmann Herbert Fruhmann NYNASO Y Ayritie 12B 01510 Vantaa Finland NYNASAB P.O. Box 10700 121 79 Stockholm Sweden

Naphthenic tire oils were used in winter tire tread compounding. Properties of compounds were compared with similar compounds made of other safe tire oils. Retreaded passenger car winter tires were prepared using the compounds. Traction and rolling resistance of the tires were determined in different weather *** was shown that naphthenie oils may lead to improvement of winter traction and rolling resistance without compromising other tire properties.

关键词： Naphthenic oil winter tire snow traction ice traction dynamic properties rolling resistance fuel economy.

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Occupational stress and its related factors among university teachers in Japan

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Health 2014年第5期6卷 299-305页

作者： mika Kataoka Kazuhiro Ozawa Masahito Tomotake Tetsuya Tanioka Beth King Christine E. Lynn College of Nursing Florida Atlantic University Boca Raton USA Department of Nursing Institute of Health Biosciences The University of Tokushima Graduate School Tokushima Japan Gifu College of Nursing Gifu Japan

The purpose of this research was to investigate occupational stress and its related factors among university teachers in Japan. Questionnaire surveys were mailed to 924 university teachers in Japan with a response rate of 43.8%, N = 405. The General Health Questionnaire 28 (GHQ-28), Multidimensional Scale of Perceived Social Support (MSPSS), short Japanese version of brief Coping Orientation to Problems Experienced (COPE) and the Work Situation Questionnaires (WSQ) developed by the authors were administered to participants. Results indicated that university teachers had some mental health problems in relation to gender, professional position, conditions of taking paid leave, job satisfaction, job control, social support, and coping skills. These findings provide evidence that in order to improve the mental health of university, teachers need to take their paid leave freely. It is important to keep high their job satisfaction levels, job control levels, and social support. The results also indicated that the ineffective coping styles lead to poor mental health. In addition, the findings identified the necessity for support of female teachers and younger lecturers, who had a greater tendency toward poor mental health.

关键词： Occupational Stress Mental Health Japan University Teachers

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战报速速看番外篇季后赛卡位战

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NBA特刊 2011年第5期 48-55页

作者： mika

东排名1↑芝加哥公牛战绩51胜19败得分985分·失分91.1分(+7.4)2008年选入状元罗斯(Derrick Rose)的公牛,当时就知道他是个能够改变球队的未来巨星,只是没想到才短短三年的时间,罗斯就将公牛队带回东区强队之林,

关键词：凯尔特人步行者球队常规赛比赛战绩开拓者公牛对手附注

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Nurses： Extending Care through Telehealth

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通讯和计算机（中英文版） 2015年第3期12卷 117-122页

作者： Maryah, ALLEN Mya, AYLOTT Margarita, LOYOLA mika, MORIC Lisa, SAFFAREK Island Health Telehealth Victoria BC V8R 118 Canada Island Health Telehealth Nanaimo BC V9S 2B7 Canada

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