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Mediterranean diet as the ideal model for preventing non-alcoholic fatty liver disease (NAFLD)

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Hepatobiliary Surgery and Nutrition 2020年第3期9卷 379-381页

作者： miguel A.martínez-González Gorka Bastarrika Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición(CIBEROBN) Institute of Health CarlosⅢMadridSpain University of Navarra Department of Preventive Medicine and Public HealthIDISNAPamplonaSpain Department of Nutrition Harvard T.H.Chan School of Public HealthBostonMAUSA University of Navarra Department of RadiologyClínica Universidad de NavarraPamplonaSpain

The prevalence of nonalcoholic fatty liver disease(NAFLD)has dramatically increased in the 2–3 last decades and it represents the most frequent global cause of liver disease,affecting 25%to 45%of adults in most studi... 详细信息

关键词： NAFLD liver prevalence

How AI-enabled SDN technologies improve the security and functionality of industrial IoT network:Architectures,enabling technologies,and opportunities

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Digital Communications and Networks 2023年第6期9卷 1351-1362页

作者： Jinfang Jiang Chuan Lin Guangjie Han Adnan MAbu-Mahfouz Syed Bilal Hussain Shah miguel martínez-García Department of Internet of Things Engineering Hohai UniversityChangzhou213022China Software College Northeastern UniversityShenyang110819China Council for Scientific and Industrial Research(CSIR) Pretoria0184South Africa School of Computing and Mathematics Manchester Metropolitan UniversityManchesterM156BHUK Department of Aeronautical and Automotive Engineering Loughborough UniversityLoughboroughLE113TTUK Department of Electrical and Electronic Engineering Science University of JohannesburgJohannesburgSouth Africa

The ongoing expansion of the Industrial Internet of Things(IIoT)is enabling the possibility of effective Industry 4.0,where massive sensing devices in heterogeneous environments are connected through dedicated communication *** brings forth new methods and models to fuse the information yielded by the various industrial plant elements and generates emerging security challenges that we have to face,providing ad-hoc functions for scheduling and guaranteeing the network ***,the large development of SoftwareDefined Networking(SDN)and Artificial Intelligence(AI)technologies have made feasible the design and control of scalable and secure IIoT *** paper studies how AI and SDN technologies combined can be leveraged towards improving the security and functionality of these IIoT *** surveying the state-of-the-art research efforts in the subject,the paper introduces a candidate architecture for AI-enabled Software-Defined IIoT Network(AI-SDIN)that divides the traditional industrial networks into three functional *** with this aim in mind,key technologies(Blockchain-based Data Sharing,Intelligent Wireless Data Sensing,Edge Intelligence,Time-Sensitive Networks,Integrating SDN&TSN,Distributed AI)and improve applications based on AISDIN are also ***,the paper also highlights new opportunities and potential research challenges in control and automation of IIoT networks.

关键词： Industrial internet of things(IIoT) Industry 4.0 Artificial intelligence(AI) Machine intelligence Software-defined networking(SDN)

A novel Ga(Ⅲ)coordination complex as an efficient sensitizer for enhancing photocatalytic activity of TiO_(2)/rGO nanocomposite

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Journal of Rare Earths 2023年第7期41卷 1004-1013,I0002页

作者： Amir Hossein Cheshme Khavar Neda Khedri Rubén Rizo Juan miguel Feliu martínez Ali Reza Mahjoub Masoumeh Doolabi Ehsan Aghayani Department of Chemistry Farhangian UniversityTehranIran Department of Chemistry Faculty of Basic SciencesTarbiat Modares UniversityTehranIran Instituto de Electroquímica y Departamento de Química Física Universidad de Alicante03080AlicanteSpain Research Center for Environmental Contaminants Abadan University of Medical SciencesAbadanIran Department of Environmental Health Engineering Abadan University of Medical SciencesAbadanIran

Narrow solar-light response range and rapid charges recombination are the main technical barriers in TiO_(2) photocatalysis *** overcome these restrictions,in this work we synthesized a novel binuclear gadolinium(Ⅲ) coordination complex,[Gd_(2)(DPDB)_6(DMF)_6(H_(2)O_()2)](DPDB=[(4-dimethylamino)phenyldiazenyl] benzenesulfonate),which was used as an inorganic sensitizer for boosting the visible light-harvesting and quantum efficiency of TiO_(2) supported-reduced graphene oxide(rGO) *** structure of [Gd_(2)(DPDB)_6(DMF)_6(H_(2)O)_(2)](Gd-CMP) was determined from single-crystal X-ray diffraction data,which indicates three-dimensional(3D) supramolecular architecture through hydrogen bonding and CH…π_(ph) *** prepared nanohybrid(Gd-CMP/TG) reveals significantly enhanced visible-light-induced photocatalytic activity for degradation of acetaminophen(ACT).The complete removal of 10 mg/L ACT is achieved over Gd-CMP/TG,and the corresponding rate constant of ACT degradation of nanohybrid is 40-fold higher than that of bare TiO_(2).In prepared ternary nanohybrid,metal-coordination sensitizer(Gd-CMP) acts as an electron donor,and at the same time,rGO serves as an electron acceptor,and the synergistic effect between them efficiently enhances charges separation and inhibits e/h pair recombination in the hybridized *** radical scavenger tests indicate that the photo-induced O_(2)^(-·) radicals dominate ACT *** the basis of the experimental results and calculated energy of electronic levels,a possible mechanism for the improved photocatalytic activity is discussed.

关键词： Gadolinium Coordination complex Sensitizer Photocatalytic Light-harvesting Rare earths

Narcea—an unknown,ancient cultivated rose variety from northern Spain

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Horticulture Research 2020年第1期7卷 2217-2228页

作者： María-Carmen martínez José-Luis Santiago Susana Boso Pilar Gago InmaculadaÁlvarez-Acero María-Estela De Vega miguel martínez-Bartolomé RafaelÁlvarez-Nogal Pilar Molíst Matteo Caser Valentina Scariot Daniel Gómez-García Misión Biológica de Galicia(CSIC) Carballeira 8Salcedo 36143 PontevedraSpain Instituto de Ciencia y Tecnología de Alimentos y Nutrición(CSIC)(Spain) C/JoséAntonio Novais 1028040 MadridSpain Departamento de Biología Molecular-Área de Biología Celular Universidad de LeónCampus de Vegazana s/n24071 LeónSpain Grupo Neurolamb Biología funcional y Ciencias de la SaludUniversidad de Vigo(Spain)36310 As Lagoas-MarcosendeSpain Department of Agricultural Forest and Food SciencesUniversity of TorinoLargo Paolo Braccini 210095 GrugliascoTurinItaly Instituto Pirenaico de Ecología(CSIC) Dpto.Conservación de Ecosistemas NaturalesAvda.Montaña S/NZaragoza50016 ZaragozaSpain

The present work reports the discovery and the complete characterisation of an ancient cultivated rose variety found growing in a private garden in the southwest of the Principality of Asturias(northern Spain).The variety is here given the name *** majority of roses currently cultivated belong to the so-called group of‘Modern Roses’,all of which were obtained after 1867 via artificial crosses and improvement *** are destined for ornamental *** the 19th century,the great majority of the many ancient cultivated roses in Europe were used in perfumery and cosmetics,or had medicinal *** damascena and Rosa centifollia are still grown and used by the French and Bulgarian perfume *** Asturian Massif of the Cantabrian Mountain Range provides a natural habitat for some 75%of the wild members of the genus Rosa,but until now there was no evidence that this area was home to ancient cultivated roses.A complete botanical description is here provided for a discovered ancient *** is also characterised according to a series of sequence tagged microsatellite sites,and its agronomic features are *** addition,a histological description(optical and scanning electronic microscope studies)of the petals is offered,along with an analysis of the volatile compounds present in these organs as determined by solid phase microextraction and gas chromatography-mass *** results reveal the uniqueness of this ancient type of rose and suggest it may be of interest to the perfume industry.

关键词： ancient southwest majority

Pollen analysis reveals the effects of uncovered interactions,pollen-carrying structures,and pollinator sex on the structure of wild bee-plant networks

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Insect Science 2024年第3期31卷 971-988页

作者： Clément Tourbez Carmelo Gómez-martínez miguelÁngel Gonzalez-Estévez Amparo Lazaro Mediterranean Institute for Advanced Studies(UIB-CSIC) Global Change Research GroupEsporlesBalearic IslandsSpain Department of Biology Ecology AreaUniversity of the Balearic/slandsPalmaSpain

Pollination networks are increasingly used to model the complexity of interactions between pollinators and flowering plants in *** methods exist to sample these interactions,with direct observations of plant-pollinator contacts in the field being by far the most *** the identification of pollen carried by pollinators allows uncovering interactions and increasing sample sizes,the methods used to build pollen-transport networks are variable and their effect on network structure remains *** understand how interaction sampling influences the structure of networks,we analyzed the pollen found on wild bees from eight communities across Mallorca Island and investigated the differences in pollen loads between bee body parts(scopa ***)and *** then assessed how these differences,as well as the uncovered interactions not detected in the field,influenced the structure of wild bee-plant *** identified a higher quantity and diversity of pollen in the scopa than in the rest of the female body,but these differences did not lead to differences in structure between plant-pollination(excluding scopa pollen)and bee-feeding interaction(including scopa pollen)***,networks built with pollen data were richer in plant species and interactions and showed lower modularity and specialization(H2'),and higher nestedness than visitation networks based on field *** interactions with plants were stronger compared to those of males,although not ***,females were more generalist(low d')and tended to be more central in interaction networks,indicating their more key role structuring pollination networks in comparison to *** study highlights the importance of palynological data to increase the resolution of networks,as well as to understand important ecological questions such as the differences between plant-pollination and bee-feeding interaction networks,and the role of sexes in pollination.

关键词： palynology pollen-transport networks pollination role of bee sexes sampling methodology visitation networks

Parental perception of child's weight,their attitudes towards child's dietary habits and the risk of obesity

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World Journal of Pediatrics 2022年第7期18卷 482-489页

作者： Lorena Garcia-Blancol Arantxa Berasaluce Andrea Romanos-Nanclares miguel Angel martinez-Gonzalez Laura Moreno-Galaraga Nerea martin-Calvo San Juan Primary Care Health Center.Servicio Navarro de Salud-Osasunbidea PamplonaSpain IdisNA.Instituto de Investigacion Sanitaria de Navrra.Pamplona Spain Department of Preventive Medicine and Public Health School of Medicine.University of NavarraC/Irunlarrea l.31080 Pamplona.Spain Biomedical Research Centre Network On Obesity and Nutrition(CIBERobn).Physiopathology of Obesity and NutritionInstituteof Health Carlos Ⅲ.Av.Monforte de Lemos.3-528029 MadridSpain Department of Nutrition.Harvard T.H.Chan School of Public Health Boston.MA 02115.USA Department of Pediatrices.Complejo Hospialario de Navarra B.Pamplona.Spain

Background The association between parental perception of child's weight and their attitudes towards his/her dietary habits has not been reported *** study aimed to assess the association between parental underestimation of child's weight and parental attitudes towards child's dietary *** We conducted a cross-sectional analysis of SENDO cohort participants recruited between January 2015 and June *** information was collected through online questionnaires completed by *** calculated crude and multivariable-adjusted odds ratio(OR)and 95%confidence intervals(CI)for unhealthy attitudes towards child's dietary habits associated with parental underestimation of child's *** Sixteen percent of children in the SENDO project had parents who underestimated their *** who under-estimated their child's weight status were more likely to have unhealthy attitudes toward his/her dietary habits[OR 3.35;95%CI(1.71-6.53)].Conclusions Parental underestimation of child's weight was associated with unhealthy attitudes towards child's dietary *** and public health practitioners should pay attention to the parental perception of child's weight to identify parents who underestimate it as an at-risk group in which to inquire about lifestyle and dietary habits.

关键词： Childhood obesity Dietary atitudes Eating habits Overweight Weight perception

4-Amino-1,8-naphthalimide based fluorescent photoinduced electron transfer (PET) pH sensors as liposomal cellular imaging agents: The effect of substituent patterns on PET directional quenching

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Frontiers of Chemical Science and Engineering 2020年第1期14卷 61-75页

作者： miguel martinez-Calvo Sandra A.Bright Emma B.Veale Adam F.Henwood D.Clive Williams Thorfinnur Gunnlaugsson School of Chemistry and Trinity Biomedical Sciences Institute(TBSI) Trinity College DublinThe University of DublinDublin 2Ireland School of Biochemistry and Immunology and Trinity Biomedical Sciences Institute(TBSI) Trinity College DublinThe University of DublinDublin 2Ireland Centro Singular de Investigacion en Quimica Bioloxica e Materiais Moleculares(CIQUS)and Departamento de Quimica Organica Universidade de Santiago de Compostela Rua Jenaro de la Fuente s/n15782Santiago de CompostelaSpain

Four new fluorescent sensors(1-4)based on the 4-amino-1,8-naphthalimide fluorophores(Naps)have been synthesized based on the classical fluorophore-spacer-receptor *** four compounds all gave rise to emission bands centred at ca.535 nm,which were found to be highly pH dependent,the emission being‘switched on’in acidic media,while being quenched due to PET from the amino moieties to the excited state of the Nap at more alkaline *** luminescent pH dependence for these probes was found to be highly dependent on the substitution on the imide site,as well as the polyamine chain attached to the position 4-amino *** the case of sensor 2 the presence of the 4-amino-aniline dominated the pH dependent ***,at higher pH,PET quenching was also found to occur from the polyamine ***,2 is better described as a receptor1-spacer1-fluorophore-spacer2-receptor2 system,where the dominant PET process is due to(normally less favourable)‘directional’PET quenching from the 4-amino-aniline unit to the Nap *** trends and pH fluorescence dependences were also seen for 3 and *** compounds were also tested for their imaging potential and toxicity against HeLa cells(using DRAQ5 as nuclear stain which does now show pH dependent changes in acidic and neutral pH)and the results demonstrated that these compounds have reduced cellular viability at moderately high concentrations(with IC50 values between ca.8-30μmol?L^?1),but were found to be suitable for intracellular pH determination at 1μmol?L^?1 concentrations,where no real toxicity was *** allowed us to employ these as lysosomal probes at sub-toxic concentrations,where the Nap based emission was found to be pH depended,mirroring that seen in aqueous solution for 1-4,with the main fluorescence changes occurring within acidic to neutral pH.

关键词： sensors pH photoinduced electron transfer cellular imaging confocal microscopy

墨西哥帕丘卡卵胎生条纹强棱蜥的繁殖周期(英文)

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动物学报 2005年第6期51卷 998-1005页

作者： Aurelio RAM■REZ-BAUTISTA Carlos A.MACIEL-MATA miguel Angel mart■nez-MORALES Centro de Investigaciones Biológicas Universidad Autónoma del Estado de HidalgoA.P.1-69 Plaza JuárezC.P.42001 Pachuca HidalgoMéxico

本文报道墨西哥伊达尔戈州帕丘卡地区干旱环境中卵胎生条纹强棱蜥的繁殖周期及特征。测定墨西哥两个科学收藏馆的浸制标本获得数据。雌雄个体达到性成熟时的体长相等,为40.0mm。雄体睾丸重量在5月开始增加,至7、8月达到最大。睾丸重量... 详细信息

本文报道墨西哥伊达尔戈州帕丘卡地区干旱环境中卵胎生条纹强棱蜥的繁殖周期及特征。测定墨西哥两个科学收藏馆的浸制标本获得数据。雌雄个体达到性成熟时的体长相等,为40.0mm。雄体睾丸重量在5月开始增加,至7、8月达到最大。睾丸重量变化与降雨量、温度和光周期均无关。雌体卵泡重量在7月开始增加,并一直持续至10月。从11月至次年7月,雌体怀有胚胎。卵黄发生及胚胎发育与光周期、温度和降雨量无关。窝仔数与雌体体长呈正相关。平均窝仔数为5.2±0.2个(2-10个)。

关键词：条纹强棱蜥角蜥科繁殖周期帕丘卡伊达尔戈墨西哥

Asthma, bronchiectasis, and chronic obstructive pulmonary disease: the Bermuda Triangle of the airways

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Chinese Medical Journal 2022年第12期135卷 1390-1393页

作者： miguel Angel martinez Garcia Joan B.Soriano Pneumology Department Hospital Universitario y Politecnico la Fe de ValenciaSpain CIBERES de enfermedades respiratorias Instituto de salud Carlos IIIMadridSpain Servicio de Neumologia Hospital Universitario de la PrincesaMadridSpain Facultad de Medicina Universidad Autonoma de MadridMadridSpain

Also known as the Devil's Triangle or Hurricane Alley,the Bermuda Triangle is an area of the Atlantic Ocean with vertices in Miami,San Juan de Puerto Rico,and Bermuda,which has been credited for causing mass disappear... 详细信息

关键词： airway obstructive Atlantic