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Neuropeptide cholecystokinin:a key neuromodulator for hippocampal functions

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Neural Regeneration Research 2025年第7期20卷 1991-1992页

作者： Fengwen Huang Stephen Temitayo bello Department of Neuroscience City University of Hong KongKowloon TongHong Kong Special Administrative RegionChina Center for Regenerative Medicine and Health Hong Kong Institute of Science&InnovationChinese Academy of SciencesHong Kong Special Administrative RegionChina

Spatial memory is crucial for survival within external surroundings and wild *** hippocampus,a critical hub for spatial learning and memory formation,has received extensive investigations on how neuromodulators shape its functions(Teixeira et al.,2018;Zhang et al.,2024).However,the landscape of neuromodulations in the hippocampal system remains poorly understood because most studies focus on classical monoamine neuromodulators,such as acetylcholine,serotonin,dopamine,and *** neuropeptides,comprising the most abundant neuromodulators in the central nervous system,play a pivotal role in neural information processing in the hippocampal ***(CCK),one of the most abundant neuropeptides,has been implicated in regulating various physiological and neurobiological statuses(Chen et al.,2019).CCK-A receptor(CCK-AR)and CCK-B receptors(CCK-BR)are two key receptors mediating the biological functions of CCK,both of which belong to class-A sevenfold transmembrane G protein-coupled receptors(Nishimura et al.,2015).CCK-AR preferentially reacts to sulfated CCK,whereas CCK-BR binds both CCK and gastrin with similar affinities(Ding et al.,2022).The expression patterns of CCK-AR and CCK-BR are distinct,implying that CCK has various functions in target *** instance,CCK-AR is widely expressed in the GI and brain subregions and is hence implicated in the control of digestive function and satiety ***,CCK-BR is abundantly and widely distributed in the central nervous system,which majorly regulates anxiety,learning,and memory(Ding et al.,2022).However,the roles of endogenous CCK and CCK receptors in regulating hippocampal function at electrophysiological and behavioral levels have received less attention.

关键词： abundant functions modulator

Transformation of leather waste into microwave-activated and N-doped carbon for Li-S batteries

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新型炭材料(中英文) 2025年

作者： Carolina Pano-Azucena Roberto Rosas-Rangel miguel Olvera-Sosa David Salvador González-González Rene Rangel-Mendez Luis Felipe Chazaro-Ruiz miguel Avalos-Borja Javier Antonio Arcibar-Orozco CIATEC.Center for Applied Innovation in Competitive Technologies Tecnologico de Monterrey School of Engineering and Sciences Instituto Potosino de Investigación Científica y Tecnológica Universidad Autónoma de Coahuila Facultad de SistemasCiudad Universitaria

The use of carbon from waste biomass has the potential to buffer the drawbacks of Li-S batteries and improve their overall performance. Chrome-Tanned-LeatherShavings(CTLS) are undesirable wastes, highly available for transformation into porous carbon. Microwave activation is an efficient state-of-the-art procedure to obtain unique porous structures and nitrogen incorporation can improve the performance of porous carbons. This study proposes the transformation of CTLS into a microwave activated porous carbon, and then was modified to introduce nitrogen. A microporous activated carbon with a specific surface area of 556 m2g-1 with honeycomb-like structure was obtained. Both urea thermal decomposition and ethanolamine impregnation improves the nitrogen and amine presence of surface groups. However,the results indicated that only urea treatment was effective in improving the initial capacity of the cell(1363 mAhg-1), which is probably linked with the sorption of long-chain polysulfides. This investigation confirms that it is possible to obtain carbon materials from CTLS, for use as sulfur-host cathodes in Li-S batteries, and improve their performance with urea thermal decomposition. Furthermore, a Radial basis function neural network was fitted to provide statistical support to the experimental results. The trained model corroborated the importance of nitrogen content of the carbons in the discharge capacity of the cells.

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Human condition monitoring in hazardous locations using pervasive RFID sensor tags and energy-efficient wireless networks

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Journal of Zhejiang University-Science C(Computers and Electronics) 2012年第9期13卷 674-688页

作者： Javier G.escribano Andrés GARCIA Autolog Group Industrial Engineering SchoolUniversity of Castilla-La ManchaAvda.Camilo José Cela s/n13071 Ciudad RealSpain

Tracking persons in dangerous situations as well as monitoring their physical condition, is often crucial for their safety. The systems commonly used for this purpose do not include individual monitoring or are too expensive and intrusive to be deployed in common situations. In this project, a mobile system based on energy-efficient wireless sensor networks (WSNs) and active radio frequency identification (RFID) has been developed to achieve ubiquitous positioning and monitoring of people in hazardous situations. The system designed can identify each individual, locate him/her, send data regarding their physical situation, and ascertain whether they are located in a confined space. A new algorithm called time division double beacon scheduling (TDDBS) has been implemented to increase operation time and data transmission rate of the nodes in the system. The results show that the use of this system allows us to find the location and state of a person, as well as to provide an analysis of the potential risks at each moment, in real time and in an energy-efficient way. In an emergency, the system also allows for quicker intervention, as it not only provides the location and causes of the event, but also informs about the physical condition of the individual at that moment.

关键词： Active RFID Wireless sensor networks (WSNs) ZigBee Human monitoring Time division double beacon sched-uling (TDDBS)

A data-driven approach to π^0,η and η＇ single and double Dalitz decays

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Chinese Physics C 2018年第2期42卷 89-105页

作者： Rafel escribano Sergi Gonzàlez-Solís Crup de Fisica Tebrica Departament de Fisica Universitat Autbnoma de Barcelona E-08193 Bellaterra (Barcelona) Spain Institut de Fisica d'Altes Energies (IFAE) The Barcelona Institute of Science and Technology (BIST) Campus UAB E-08193 Bellaterra (Barcelona) Spain CAS Key Laboratory of Theoretical Physics Institute of Theoretical Physics Chinese Academy of Sciences Beijing 100190 China

The dilepton invariant mass spectra and integrated branching ratios of the single and double Dalitz decays P→l^＋l^-γ and P→l^＋l^-l^＋l^-（P=π^0,η,η＇;l=e or μ） are predicted by means of a data-driven approach based on the use of rational approximants applied to π^0,η and η＇ transition form factor experimental data in the space-like region.

关键词： electromagnetic processes and properties phenomenological models transition form factor

Minimally invasive treatment of pancreatic necrosis

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World Journal of Gastroenterology 2012年第46期18卷 6829-6835页

作者： Brian bello Jeffrey B Matthews Department of Surgery School of Medicine University of Chicago

AIM: To systematically review these minimally invasive approaches to infected pancreatic necrosis. METHODS: We used the MEDLINE database to investigate studies between 1996 and 2010 with greater than 10 patients that examined these techniques. Using a combination of Boolean operators, reports were retrieved addressing percutaneous therapy (341 studies), endoscopic necrosectomy (574 studies), laparoscopic necrosectomy via a transperitoneal approach (148 studies), and retroperitoneal necrosectomy (194 studies). Only cohorts with at least 10 or more patients were included. Non-English papers, letters, animal studies, duplicate series and reviews without original data were excluded, leaving a total of 27 studies for analysis. RESULTS: Twenty-seven studies with 947 patients total were examined (eight studies on percutaneous approach; ten studies on endoscopic necrosectomy; two studies on laparoscopic necrosectomy via a transperitoneal approach; five studies on retroperitoneal necrosectomy; and two studies on a combined percutaneous-retroperitoneal approach). Success rate, complications, mortality, and number of procedures were outcomes that were included in the review. We found that most published reports were retrospective in nature, and thus, susceptible to selection and publication bias. Few reports examined these techniques in a comparative, prospective manner. CONCLUSION: Each minimally invasive approach though was found to be safe and feasible in multiple reports. With these new techniques, treatment of infected pancreatic necrosis remains a challenge. We advocate a multidisciplinary approach to this complex problem with treatment individualized to each patient.

关键词： Acute pancreatitis Pancreatic abscess Pancreatic necrosis Necrosectomy Laparoscopic necrosectomy

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迷失丛林 Sonora鸡尾酒吧

室内设计与装修 2025年第1期 148-149页

作者：无 Ricard Fabregat Rafaela Aranzaens Michele Soares Yesica Pena Maria di bello Adria Goula(摄影) 夏花(编译) EL EQUIPO CREATIVO 不详

Sonora鸡尾酒吧位于阿姆斯特丹Nhow酒店的顶层。其三角形的布局让空间更显紧凑,由OMA建筑事务所及建筑师RemKoolhaas设计的落地玻璃幕墙,提供了欣赏阿姆斯特丹新区壮丽景观的机会。设计师面临的挑战在于,要如何让鸡尾酒吧在与这些美景... 详细信息

Sonora鸡尾酒吧位于阿姆斯特丹Nhow酒店的顶层。其三角形的布局让空间更显紧凑,由OMA建筑事务所及建筑师RemKoolhaas设计的落地玻璃幕墙,提供了欣赏阿姆斯特丹新区壮丽景观的机会。设计师面临的挑战在于,要如何让鸡尾酒吧在与这些美景的竞争中脱颖而出。

关键词：建筑事务所玻璃幕墙阿姆斯特丹鸡尾酒建筑师三角形酒店

Discontinuities effect on drilling condition and performance of selected rocks in Nigeria

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International Journal of Mining Science and Technology 2014年第5期24卷 603-608页

作者： Adebayo Babatunde bello Wasiu Ademola Department of Mining Engineering Federal University of Technology

The study examined joint discontinuity spacing effect on drilling condition and performance in selected rocks in llorin and Ibese areas, Nigeria. Five samples for each rock type （gneiss and limestone） were tested in the laboratory for chemical, physical and mechanical properties. Dip direction and joint spacing were measured using compass clinometers. The chemical composition was determined using X-ray Fluores- cence （XRF） spectrometer. The results show that gneiss has SiO2 of 61.88g and limestone has CaO content of 52.3g. The average dry density of gneiss and limestone are 2.6 and 2.39 g/cm^3, respectively. The uniaxial compressive strength of gneiss and limestone are 195 and 93.83 MPa, respectively. These rocks are classified as strong and moderately strong rock. Gneiss and limestone have mean joint discontinuity spacing of 0.79 and 0.25 m, which classified them as moderate and wide joint spacing respectively. Joint spacing was correlated with specific energy, bit wear and uniaxial compressive using Statistical Package for Social Science （SPSS）. The regression model has multiple coefficient of correlation of R^2 = 0.791 and R^2 =0.995 for gneiss and limestone, respectively. The variation in joint spacing could be attributed to spe- cific energy, bit wear and uniaxial compressive strength which affect drilling condition and performance. Ultimately, as joint spacing gets closer, the drilling velocity increases, drill string will be stable.

关键词： Joint spacing GneissLimestone Regression Composition

Effluent Zero Release Concept-The Brazilian Experience

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过程工程学报 2006年第4期6卷 691-696页

作者： José Carlos Mierzwa Sandra Mara Garcia bello Ivanildo Hespanhol Hydraulic and Sanitation Eng.Dept. Univ.Sao PauloAv.Prof.Almeida Prado83 SoPauloBrazil CEP:05508-900 Navy Technologic Center in Sao Paulo Av.Prof.Lineu Prestes2468 SoPauloBrazilCEP:05508-900

Water scarcity is pushing the government,industries and researchers to the development of new strategies for water and wastewater *** approach aimed at the optimization of the water use and minimization of effluent generation was developed at the Centro Experimental ARAMAR(CEA),a nuclear research facility,located in the State of Sao Paulo,*** scale tests followed by a pilot plant treating effluents from some nuclear research facilities have shown the results leading to the conclusion that the effluent zero release concept is *** on the gathered data,a project of an integrated effluent treatment system focusing on water recovery and environmental effluent release reduction has been developed.

关键词： effluent wastewater treatment zero release

EXTRACTING BEHAVIOURAL MODELS FROM 2010FIFA WORLD CUP

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Journal of Systems Science & Complexity 2013年第1期26卷 43-61页

作者： MENNDEZ Héctor bello-ORGAZ Gema CAMACHO David Department of Computer Science Universidad Autnoma de Madrid

The FIFA World Cup^(TM) is the most profitable worldwide *** FIFA publishes global statistics of this competition which provide global data about the players and teams during the *** work is focused on the extraction of behavioural patterns for both,players and teams strategies,through the automated analysis of this *** knowledge and models extracted in this work could be applied to soccer leagues or even it could be oriented to sport ***,the main contribution is related to the study on several automatic knowledge extraction techniques,such as clustering methods,and how these techniques can be used to obtain useful behavioural models from a global statistics *** information provided by the clustering algorithms shows similar properties which have been combined to define the models,making the human interpretation of these statistics ***,the most successful teams strategies have been analysed and compared.

关键词： Behavioural patterns clustering FIFA World Cup football soccer web mining.