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Enhancement of a foaming formulation with a zwitterionic surfactant for gas mobility control in harsh reservoir conditions

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Petroleum Science 2021年第5期18卷 1409-1426页

作者： miguel angel Roncoroni Pedro Romero Jesús Montes Guido Bascialla Rosario Rodríguez Ramón Rodríguez Pons-Esparver Luis Felipe Mazadiego María Flor García-Mayoral Universidad Politécnica de Madrid MadridSpain CEPSA Research Center MadridSpain CEPSA E&P MadridSpain

This work presents the design of a robust foam formulation that tolerates harsh reservoir conditions(high salinity,high divalent ion concentration,high temperature,light oil,and hydrocarbon injection gas)in a sandstone *** this,we selected anionic Alpha Olefin Sulfonate(AOS)surfactants and studied their synergistic effects in mixtures with zwitterionic betaines to enhance foam *** laboratory workflow used to define the best formulation followed a de-risking approach in three consecutive ***,(phase 1)the main surfactant(AOS)was selected among a series of commercial candidates in static ***,(phase 2)the betaine booster to be combined with the previously selected AOS was chosen and their ratio optimized in static ***,(phase 3)the surfactant/booster ratio was optimized under dynamic conditions in a porous medium in the absence and the presence of *** a result of this study,a mixture of an AOS C14-C16 and cocamidopropyl hydroxysultaine(CAPHS)was selected as the one having the best *** designed formulation was proven to be robust in a wide range of *** generated a strong and stable foam at reservoir conditions,overcoming variations in salinity and foam quality,and tolerated the presence of oil.

关键词： Gas mobility control Foam enhanced oil recovery(EOR) Foam stability High temperature high salinity reservoir Surfactant formulation

Microscopic theory of light-induced ultrafast skyrmion excitation in transition metal films

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npj Computational Materials 2022年第1期8卷 598-604页

作者： Emil Viñas Boström angel Rubio Claudio Verdozzi Max Planck Institute for the Structure and Dynamics of Matter Luruper Chaussee 14922761HamburgGermany Center for Computational Quantum Physics(CCQ) The Flatiron Institute162 Fifth AvenueNew YorkNY10010USA Division of Mathematical Physics and ETSF Lund UniversityPO Box 11822100LundSweden

Magnetic skyrmions are topological excitations of great promise for compact and efficient memory ***,to interface skyrmionics with electronic devices requires efficient and reliable ways of creating and destroying such *** this work,we unravel the microscopic mechanism behind ultrafast skyrmion generation by femtosecond laser pulses in transition metal thin *** employ a theoretical approach based on a two-band electronic model,and show that by exciting the itinerant electronic subsystem with a femtosecond laser ultrafast skyrmion nucleation can occur on a 100 fs *** combining numerical simulations with an analytical treatment of the strong s–d exchange limit,we identify the coupling between electronic currents and the localized d-orbital spins,mediated via Rashba spin–orbit interactions among the itinerant electrons,as the microscopic and central mechanism leading to ultrafast skyrmion *** results show that an explicit treatment of itinerant electron dynamics is crucial to understand optical skyrmion generation.

关键词： excitation transition topological

Healthy diet,depression and quality of life:A narrative review of biological mechanisms and primary prevention opportunities

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World Journal of Psychiatry 2021年第11期11卷 997-1016页

作者： Octavio Pano Elena H Martínez-Lapiscina Carmen Sayón-Orea miguel angel Martinez-Gonzalez Jose Alfredo Martinez Almudena Sanchez-Villegas Preventive Medicine and Public Health University of NavarrePamplona 31008Spain Department of Neurology Center of Neuroimmunology Hospital Clinic of BarcelonaInstitut d’Investigacions Biomèdiques August Pi SunyerBarcelona 08036Spain Department of Preventive Medicine and Public Health University of NavarraPamplona 31008Spain IdiSNA Navarra Institute for Health ResearchPamplona 31008Spain Department of Public Health Navarra Institute of Public Health and EpidemiologyPamplona 31003Spain CIBER Pathophysiology of Obesity and Nutrition Institute of Health Carlos IIIMadrid 28049Spain Department of Nutrition Harvard T.H.Chan School of Public HealthBostonMA 02115United States Department of Food Sciences and Physiology University of NavarrePamplona 31008Spain Precision Nutrition and Cardiometabolic Health Program IMDEA Food InstituteMadrid 28049Spain Department of Clinical Sciences University of Las Palmas Gran CanariaLas Palmas Gran Canaria 35080Spain

Unipolar depressive disorder(UDD)affects more than 264 million people worldwide and was projected well before the severe acute respiratory syndrome coronavirus 2 pandemic to be the leading cause of disability-adjusted life years lost in *** is imperative for leading economies to implement preventive strategies targeted towards UDD,given consistent policies are currently *** established similarities between the aetiological hypotheses of depression and cardiometabolic diseases are shifting paradigms within this *** is believed that dietary practices could potentially reduce the incidence of depression;similar to their effects on ***,the aim of this review was to compile current evidence on healthy dietary patterns as suitable contributors towards primary prevention strategies against *** of the well-known biological mechanisms behind depression have been positively associated with healthful diets and dietary patterns to varying ***,a common factor of UDD is the production and overall effects of inflammatory cytokines,such as interleukin-6,tumor necrosis factor-α,and Creactive *** compounds have been associated with depressive symptoms,disturbances in neuroendocrine function,leaky gut,monoamine activity and brain function,while also being key factors in the development of cardiometabolic *** Mediterranean diet(MD)in particular,is well supported by first-level evidence regarding its preventive qualities against metabolic and cardiovascular diseases and thus considered a model for healthy eating by various *** one of the few clinical trials investigating these associations,the PREDIMED trial,individuals with diabetes assigned to a MD supplemented with mixed tree nuts experienced a 41%relative risk reduction for developing ***,there is a need to include health related quality of life as an indicator of physical and mental well-being,considering its putative associations

关键词： Depression Nutrition Mediterranean Quality of life Primary prevention Epidemiology

Role of gastrin-peptides in Barrett's and colorectal carcinogenesis

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World Journal of Gastroenterology 2012年第45期18卷 6560-6570页

作者： Eduardo Chueca angel Lanas Elena Piazuelo IIS Aragon Aragon Institute of Health Sciences50009 ZaragozaSpain Networked Biomedical Research Center Hepatic and Digestive Diseases(CIBERehd) C/Corcega 180 bajos dcha08036 BarcelonaSpain Department of Medicine Psychiatry and DermatologyMedical University of ZaragozaC/Domingo Miral50009 ZaragozaSpain Service of Gastroenterology Hospital Clinico UniversitarioAvda.San Juan Bosco 1550009 ZaragozaSpain

Gastrin is the main hormone responsible for the stimulation of gastric acid secretion;in addition,gastrin and its derivatives exert proliferative and antiapoptotic effects on several cell *** synthesis and secretion are increased in certain situations,for example,when proton pump inhibitors are *** impact of sustained hypergastrinemia is currently being *** vitro experiments and animal models have shown that prolonged hypergastrinemia may be related with higher cancer rates;although,this relationship is less clear in human *** gastrin levels have been shown to cause hyperplasia of several cell types;yet,the risk for developing cancer seems to be the same in normo-and hypergastrinemic *** tumors also produce their own gastrin,which can act in an autocrine manner promoting tumor *** cancers are extremely dependent on gastrin to *** research focused only on the effects of amidated gastrins,but there has been an interest in intermediates of gastrin in the last few *** intermediates aren't biologically inactive;in fact,they may exert greater effects on proliferation and apoptosis than the completely processed *** certain gastrin overproduction states,they are the most abundant gastrin peptides *** purpose of this review is to examine the gastrin biosynthesis process and to summarize the results from different studies evaluating the production,levels,and effects of the main forms of gastrin in different overexpression states and their possible relationship with Barrett's and colorectal carcinogenesis.

关键词：胃泌素大肠癌癌症发病率胃酸分泌质子泵抑制剂肽肿瘤生长合成过程

Diabetes mellitus contribution to the remodeling of the tumor microenvironment in gastric cancer

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World Journal of Gastrointestinal Oncology 2021年第12期13卷 1997-2012页

作者： Armando Rojas Cristian Lindner Iván Schneider Ileana Gonzàlez Hernan Araya Erik Morales Milibeth Gómez Nelson Urdaneta Paulina Araya miguel angel Morales Biomedical Research Lab. Medicine FacultyCatholic University of MauleTalca 34600000Chile Department of Clinical Sciences Medicine FacultyCatholic University of MauleTalca 34600000Chile Servicio de Oncología Hospital Regional de TalcaTalca 34600000Chile Servicio de Anatomía Patologica Hospital Regional de TalcaTalca 34600000Chile Department of Molecular and Clinical Pharmacology Program Institute of Biomedical SciencesUniversity of ChileSantiago 8320000Chile

Compelling pieces of evidence derived from both clinical and experimental research has demonstrated the crucial contribution of diabetes mellitus(DM)as a risk factor associated with increased cancer incidence and mortality in many human neoplasms,including gastric cancer(GC).DM is considered a systemic inflammatory disease and therefore,this inflammatory status may have profound effects on the tumor microenvironment(TME),particularly by driving many molecular mechanisms to generate a more aggressive *** is an active driver in the modification of the behavior of many cell components of the TME as well as altering the mechanical properties of the extracellular matrix(ECM),leading to an increased ECM ***,DM can alter many cellular signaling mechanisms and thus favoring tumor growth,invasion,and metastatic potential,as well as key elements in regulating cellular functions and cross-talks,such as the microRNAs network,the production,and cargo of exosomes,the metabolism of cell stroma and resistance to *** the present review,we intend to highlight the mechanistic contributions of DM to the remodeling of TME in GC.

关键词： Diabetes mellitus Gastric cancer Tumor microenvironment Hyperglycemia Chronic inflammation

DNA Fidelity: Expression of a Monocot Promoter in a Dicot Plant

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American Journal of Plant Sciences 2022年第1期13卷 50-59页

作者： Luis María Suárez-Rodríguez Hugh Mason Joel Ramírez-Cabrera Luis Jorge Saucedo miguel angel Gómez-Lim Charles Arntzen Rodolfo López-Gómez Instituto de Investigaciones Químico-Biológicas Universidad Michoacana de San Nicolás de Hidalgo Morelia México School of Life Sciences Arizona State University Tempe USA Departamento de Genética Cinvestav IPN Campus Irapuato Irapuato México

The knowledge generated from the identification of plant promoters has been very important for plant biotechnology development. The use of promoters in transgenic plants allows a reasonable level of regulating protein expression. With the application of reporter genes, such as gusA (uidA,) the production of a colored protein, β-glucuronidase, can be detected and measured both qualitatively and quantitatively, and the activity of the promoter can be assessed. In this work we use a promoter of an abundant banana fruit protein gene Musa acuminata Acidic Chitinase class III a monocot species, to drive expression of gusA in a dicot species, like tomato. We evaluated the monocot promoter capabilities by localizing and quantifying β-glucuronidase (GUS) expression through fluorometric assays during tomato fruit ripening. Our results suggest that this promoter could be used for specifically strong fruit protein expression in dicot plants.

关键词： Promoter Fruit Ripening Tomato Banana

Peaks over Manifold (POM): A Novel Technique to Analyze Extreme Events over Surfaces

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Advances in Pure Mathematics 2022年第1期12卷 48-62页

作者： Gonzalo Perera angel M. Segura CURE Rocha Uruguay

We present a novel method to analyze extreme events of flows over manifolds called Peaks Over Manifold (POM). Here we show that under general and realistic hypotheses, the distribution of affectation measures converges to a Generalized Pareto Distribution (GPD). The method is applicable to floods, ice cover extent, extreme rainfall or marine heatwaves. We present an application to a synthetic data set on tide height and to real ice cover data in Antartica.

关键词： Peaks Over Thresholds (POT) Generalized Pareto Distribution Extreme Events

Morphological Characterization and Phenological Modeling of <i>Jatropha platyphylla</i>(Euphorbiaceae) Muell. Arg. Genotypes

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American Journal of Plant Sciences 2022年第1期13卷 23-35页

作者： Edith Salazar-Villa Martha Lidia Gutiérrez-Pérez Federico Soto-Landeros Karla Marina Báez-Parra María de la Paz Sosa-Segura miguel angel Angulo-Escalante Centro de Investigación en Alimentación y Desarrollo AC Culiacán México Facultad de Agronomía Universidad Autónoma de Sinaloa Culiacán México Instituto Tecnológico Superior de Guasave Guasave México Facultad de Ciencias Químico Biológicas Universidad Autónoma de Sinaloa Culiacán México Colegio de Bachilleres del Estado de Sinaloa Culiacán México

Morphological characterization and phenological modeling were carried out on genotypes of Jatropha platyphylla collected from the states of Sinaloa and Durango, Mexico. The morphological characterization evidenced the existence of monoecious plants, finding individuals with male and female flowers in the same inflorescence. Fruit with four seeds was also found. The phenological study was divided into two phases and calculated in thermal requirement (°D): Vegetative [seedtime (0), germination (24), emergence (98), cotyledons (87), second (302) and fourth (524) true leaves, end of vegetative growth (302)] and reproductive [flowering (303), fructification (342), maturation (126), defoliation and senescence (450)]. The thermal constant (2558) was similar in all eight genotypes. The phenological stages and the accumulated degree days were adjusted with a third-degree polynomial (Stage = -0.0041x3 + 0.7446x2 - 8.6808x + 6.2448) (R2 = 0.99%) stage. The development of phenological models facilitates the prediction of the flowering date for the selection of varieties with high oil and protein content.

关键词： Degree-Days Monoecious Phenological Modeling Plant Breeding Varietal Selection

Catatonia in older adults:A systematic review

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World Journal of Psychiatry 2022年第2期12卷 348-367页

作者： Walter Jaimes-Albornoz angel Ruiz de Pellon-Santamaria Ayar Nizama-Vía Marco Isetta Ines Albajar Jordi Serra-Mestres Psychiatry Service Hospital Universitario DonostiaBasque Health Service-OsakidetzaSan Sebastian 20014GipuzkoaSpain Psychiatry Service“Virgen del Cisne”Mental Health Community Center Regional Health DirectorateTumbes 24002Peru Library and Knowledge Services Central&North West London NHS Foundation TrustSt Charles’HospitalLondon W106DZUnited Kingdom Neurology Service Hospital Universitario DonostiaBasque Health Service-OsakidetzaSan Sebastian 20014GipuzkoaSpain Old Age Psychiatry Service Cardinal ClinicWindsor SL45ULUnited Kingdom

BACKGROUND Catatonia is a complex psychomotor syndrome that often goes unrecognized and untreated,even though its classification has evolved in recent *** and correct identification of catatonia allows for highly effective treatment and prevention of possible *** underrecognition of catatonia in older patients is also frequent,and research in this population is *** To conduct a systematic review of the literature on catatonia in older people to ascertain its clinical characteristics across *** Following the PRISMA guidelines,MEDLINE,EMBASE,and PsycINFO databases were searched from inception to December 2021,with a strategy aimed at identifying all articles published on catatonia in older *** and abstracts were scanned and selected independently by two *** investigating issues related to catatonia and/or catatonic symptoms in older people,with English abstracts available,were *** of selected articles were revised to identify other relevant *** In total,1355 articles were *** removing duplicates,879 *** the 879 identified abstracts,669 were excluded because they did not meet the inclusion criteria.A total of 210 articles underwent full text review,and 51 were eliminated for various *** more articles were selected from the ***,173 articles were reviewed:108 case reports,35 case series,11 prospective cohort studies,6 case-control studies,3 retrospective cohort studies and 10 *** found several particular aspects of catatonia in this *** in older patients is highly prevalent and tends to have a multifactorial *** patients,compared to younger patients,have a higher risk of developing catatonia with benzodiazepine(BZD)withdrawal,in bipolar disorder,and in the general ***,together with other risk factors,was significantly associated with the incidence of deep venous thrombosis,neuroleptic malig

关键词： Catatonia Older adults Etiology Phenomenology Prevalence Treatment