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Towards trustworthy multi-modal motion prediction:Holistic evaluation and interpretability of outputs

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CAAI Transactions on Intelligence Technology 2024年第3期9卷 557-572页

作者： Sandra Carrasco Limeros Sylwia Majchrowska Joakim Johnander Christoffer Petersson miguelÁngel Sotelo David Fernández Llorca Computer Engineering Department Polytechnic SchoolUniversity of AlcalaMadridSpain AI Sweden GothenburgSweden Zenseact AB GothenburgSweden Department of Electrical Engineering Linköping UniversityLinköpingSweden Chalmers University of Technology GothenburgSweden European Commission Joint Research CentreSevilleSpain

Predicting the motion of other road agents enables autonomous vehicles to perform safe and efficient path *** task is very complex,as the behaviour of road agents depends on many factors and the number of possible future trajectories can be consid-erable(multi-modal).Most prior approaches proposed to address multi-modal motion prediction are based on complex machine learning systems that have limited ***,the metrics used in current benchmarks do not evaluate all aspects of the problem,such as the diversity and admissibility of the *** authors aim to advance towards the design of trustworthy motion prediction systems,based on some of the re-quirements for the design of Trustworthy Artificial *** focus is on evaluation criteria,robustness,and interpretability of ***,the evaluation metrics are comprehensively analysed,the main gaps of current benchmarks are identified,and a new holistic evaluation framework is ***,a method for the assessment of spatial and temporal robustness is introduced by simulating noise in the perception *** enhance the interpretability of the outputs and generate more balanced results in the proposed evaluation framework,an intent prediction layer that can be attached to multi-modal motion prediction models is *** effectiveness of this approach is assessed through a survey that explores different elements in the visualisation of the multi-modal trajectories and *** proposed approach and findings make a significant contribution to the development of trustworthy motion prediction systems for autono-mous vehicles,advancing the field towards greater safety and reliability.

关键词： autonomous vehicles evaluation interpretability multi-modal motion prediction robustness trustworthy AI

Short term temporal variability of selected organophosphate esters among healthy adults living in the National Capital Region of Canada

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Emerging Contaminants 2024年第3期10卷 293-303页

作者： Shabana Siddique Gong Zhang Rocio Aranda-rodriguez Leonora Marro Cariton Kubwabo Environmental Health Science and Research Bureau Health CanadaOttawaONK1A 0K9Canada

Organophosphate esters(OPEs)are used primarily as flame-retardants and *** are commonly detected in various environmental matrices,food and drinking water,and their metabolites are frequently found and quantified in *** adverse impacts on human health,including carcinogenicity,neurotoxicity,developmental and reproductive toxicity have been well *** concentration of OPE metabolites can vary in the same individual,depending on the sampling time,thus introducing significant uncertainty in exposure *** current study focusses on the assessment of short term temporal variability in adult men and women residing in Canada's Capital *** OPE metabolites were analyzed in 562 daily urine samples,collected every three days for five weeks from 11 *** extraction procedure was performed on an automated SPE and extracts analyzed using UPLC-MS/*** spot urine samples as well as first morning void(FMV),the detection frequency was greater than 50%for bis(2-chloroethyl)hydrogen phosphate(BCEP),bis(1-chloro-2-propyl)phosphate(BCIPP),bis(1,3-dichloro-2-propyl)phosphate(BDCIPP),diphenyl phosphate(DPHP)and bis(2,4-ditert-butylphenyl)hydrogen phosphate(B2,4DtBPP).Significant difference was observed in males and females for BCEP and ***-class correlation coefficient(ICC)for creatinine corrected data for the spot urine samples ranged from 0.37 to *** reproducibility was observed for creatinine corrected DPHP and BCIPP in both spot urine and FMV *** variation was observed between study participants in the spot urine samples when compared to the FMV ***,when considering diurnal difference there was a considerable inter-day variation in the FMV samples compared to the spot *** strength of the study is that the participants belonged to the same geographical location and working in the same facility,hence spatial variability did not influence the outcome of the results.

关键词： Organophosphate esters Flame retardants Plasticizers Temporal variability Canada

Optimal Design of Hybrid Microgrid in Isolated Communities of Ecuador

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Journal of Modern Power Systems and Clean Energy 2024年第2期12卷 488-499页

作者： Luis A.Pesantes Ruben Hidalgo-León Johnny Rengifo miguel Torres Jorge Aragundi JoséCordova-Garcia Luis F.Ugarte Facultad de Ingeniería en Electricidad y Computación of Escuela Superior Politécnica del Litoral(ESPOL)University GuayaquilEcuador Department of Electrical Engineering at Universidad Técnica Federico Santa María SantiagoChile IEEE

In rural territories, the communities use energy sources based on fossil fuels to supply themselves with electricity, which may address two main problems: greenhouse gas emissions and high fuel prices. Hence, there is an opportunity to include renewable resources in the energy mix. This paper develops an optimization model to determine the optimal sizing, the total annual investment cost in renewable generation, and other operating costs of the components of a hybrid microgrid. By running a k-means clustering algorithm on a meteorological dataset of the community under study, the hourly representative values become input parameters in the proposed optimization model. The method for the optimal design of hybrid microgrid is analyzed in six operating scenarios considering:(1) 24-hour continuous power supply;(2) load shedding percentage;(3) diesel power generator(genset) curtailment;(4) the worst meteorological conditions;(5) the use of renewable energy sources including battery energy storage systems(BESSs);and(6) the use of genset. A mathematical programming language(AMPL) tool is used to find solutions of the proposed optimization model. Results show that the total costs of microgrid in the scenarios that cover 100% of the load demand(without considering the scenario with 100% renewables) increase by over 16% compared with the scenario with genset operation limitation. For the designs with power supply restrictions, the total cost of microgrid in the scenario with load shedding is reduced by over 27% compared with that without load shedding.

关键词： Battery energy storage system(BESS) isolated community microgrid renewable energy optimization

Diplopoda in the world fossil record

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Zoological Systematics 2024年第3期49卷 185-245页

作者： Michelle Álvarez-Rodríguez Francisco Riquelme miguel Hernández-Patricio Fabio Cupul-Magaña Laboratorio de Sistemática Molecular Escuela de Estudios Superiores del JicareroUniversidad Autónoma del Estado de MorelosC.P.62909JojutlaMorelosMexico MMRN Centro de Investigaciones BiológicasUniversidad Autónoma del Estado de MorelosC.P.62209CuernavacaMorelosMexico Unafíliate Centro Universitario de la Costa Universidad de GuadalajaraC.P.48280Puerto VallartaJaliscoMexico

We present a comprehensive catalog with an updated database of the fossil record of Diplopoda in the *** data was collected from descriptions and reports published from 1854 to the *** also include new records from Mexican amber(Upper Oligocene-Lower Miocene),counting 83 unknown fossil inclusions,with the first records of the orders Polyxenida,Platydesmida,and Julida,as well as the families Sphaeriodesmidae and Trichopolydesmidae within *** to our results,Diplopoda counts 413 records featuring 299 distinct taxa ranging from the Middle Silurian to the Upper Pleistocene,representing three subclasses,two subterclasses,six superorders,25 orders,15 superfamilies,55 families,93 genera,and 161 fossil *** date,no fossils of the order Siphonocryptida have been *** fossil record extends over three geological eras:the Paleozoic,with 161 taxa,including 97 species;the Mesozoic,with 53 taxa and 22 species;and the Cenozoic,with 85 taxa and 42 *** referred material shows different forms of fossil *** comprises 123 impressions,99 compressions,26 ichnites,predominantly from Paleozoic and Mesozoic sediments,and 165 amber inclusions from late Mesozoic and Cenozoic ***,this catalog allows us to estimate the size and taxonomic composition of Diplopoda in the fossil record worldwide.

关键词： Millipedes Paleozoic Mesozoic Cenozoic new records catalog

A comprehensive look at the psychoneuroimmunoendocrinology of spinal cord injury and its progression: mechanisms and clinical opportunities

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Military Medical Research 2024年第2期11卷 228-267页

作者： miguel A.Ortega Oscar Fraile-Martinez Cielo García-Montero Sergio Haro miguel Ángel Álvarez-Mon Diego De Leon-Oliva Ana M.Gomez-Lahoz Jorge Monserrat Mar Atienza-Pérez David Díaz Elisa Lopez-Dolado Melchor Álvarez-Mon Department of Medicine and Medical Specialities University of Alcala28801 Alcala de HenaresSpain Ramón y Cajal Institute of Sanitary Research(IRYCIS) 28034 MadridSpain Department of Psychiatry and Mental Health Hospital Universitario Infanta Leonor28031 MadridSpain Service of Rehabilitation National Hospital for Paraplegic PatientsCarr.de la PeraledaS/N45004 ToledoSpain Immune System Diseases‑Rheumatology Service and Internal Medicine University Hospital Príncipe de Asturias(CIBEREHD)28806 Alcala de HenaresSpain

Spinal cord injury(SCI)is a devastating and disabling medical condition generally caused by a traumatic event(primary injury).This initial trauma is accompanied by a set of biological mechanisms directed to ameliorate neural damage but also exacerbate initial damage(secondary injury).The alterations that occur in the spinal cord have not only local but also systemic consequences and virtually all organs and tissues of the body incur important changes after SCI,explaining the progression and detrimental consequences related to this ***(PNIE)is a growing area of research aiming to integrate and explore the interactions among the different systems that compose the human organism,considering the mind and the body as a *** initial traumatic event and the consequent neurological disruption trigger immune,endocrine,and multisystem dysfunction,which in turn affect the patient's psyche and *** the present review,we will explore the most important local and systemic consequences of SCI from a PNIE perspective,defining the changes occurring in each system and how all these mechanisms are ***,potential clinical approaches derived from this knowledge will also be collectively presented with the aim to develop integrative therapies to maximize the clinical management of these patients.

关键词： Spinal cord injury(SCI) Psychoneuroimmunoendocrinology(PNIE) Secondary injury Immunoinflammatory dysfunction Gut microbiota Translational opportunities

In‑depth proteome characterization of endometrium and extraembryonic membranes during implantation in pig

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Journal of Animal Science and Biotechnology 2024年第3期15卷 1027-1055页

作者： Maria A.Gil Josep M.Cambra Heriberto rodriguez‑Martinez Cristina Cuello Inmaculada Parrilla Emilio A.Martinez Department of Medicine and Animal Surgery International Excellence Campus for Higher Education and Research“Campus Mare Nostrum”University of MurciaMurciaSpain Institute for Biomedical Research of Murcia(IMIB-Pascual Parrilla) MurciaSpain Technical University of Munich MunichGermany Department of Biomedical&Clinical Sciences(BKV) BKH/Obstetrics&GynaecologyLinkoping UniversityLinkopingSweden

Background Proteome characterization of the porcine endometrium and extraembryonic membranes is important to understand mother-embryo *** this study,the proteome of the endometrium and cho-rioallantoic membrane was characterized in pregnant sows(PS)during early gestation(d 18 and 24 of gestation)and in the endometrium of non-pregnant sows(NPS)during the same days using LC-MS/MS *** UniProtKB database and ClueGO were used to obtain functional Gene Ontology annotations and biological and functional networks,*** Our analysis yielded 3,254 and 3,457 proteins identified in the endometrium of PS and NPS,respectively;of these,1,753 being common while 1,501 and 1,704 were exclusive to PS and NPS,*** addition,we iden-tified 3,968 proteins in the extraembryonic membranes of *** analyses of function revealed some proteins had relevance for the immune system process and biological adhesion in endometrium while the embryonic chorion displayed abundance of proteins related to cell adhesion and cytoskeletal organization,suggesting they dominated the moment of endometrial remodeling,implantation and adhesion of the lining *** are available via Pro-teomeXchange with identifier *** This is the first in-depth proteomic characterization of the endometrium and extraembryonic mem-branes during weeks 3 to 4 of gestation;data that contribute to the molecular understanding of the dynamic environ-ment during this critical period,associated with the majority of pregnancy losses.

关键词： Endometrium Extraembryonic membranes Implantation Pig Proteome

Alcohol and illicit drugs:prevalence of alcohol and illicit drug use and their predictors in young people from Argentina,Bulgaria,Chile and Romania

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Global Health Journal 2024年第1期8卷 16-23页

作者： Daniel Vankov David Jankovszky Borislav Vankov Martin Galanternik Claudia rodriguez Michiel de Ruyter Scientific Organization from Partium Oradea 410204Romania Queensland University of Technology BrisbaneQueensland 4001Australia Association for Youth and Students in Partium Oradea 410102Romania Community Centre Bright Day-2009 Vidin 3700Bulgaria MiNU Civil.Association Buenos Aires 4918Argentina ONG No Chat Santiago 832000Chile

Background:Alcohol and illicit drugs(AID)continue to be a major global health *** preventable,AID is linked to millions of deaths annually *** situation is particularly grave for young people,with AID being a major direct risk factor for disability-adjusted youth life-years lost and *** further contributes to assaults,road crashes,accidental poisoning,and suicide,leading to long-term issues and public health ***:This study aimed at disclosing current AID prevalence data for Argentinian,Bulgarian,Chilean and Romanian *** shed light on the predictors of AID in young people from those ***:The study used an online survey to gather data from people aged 18 to 25(n=1,297).The survey was underpinned by the theory of planned behaviour(TPB).Predictors were investigated separately for drinking alcohol and using illicit ***:Our data revealed that across the four target countries,49%to 90%of the participants drank alcohol,and 8%to 35%used illicit drugs in the past three *** 20%and 91%of them intended to drink,and between 8%and 31%intended to use illicit drugs in the following three *** TPB model predicted statistically significant(P<0.001)amounts of variance in drinking alcohol(between 61%and 72%)and using illicit drugs(between 20.3%and 74.4%).Intention was consistent in significantly predicting both *** around the predictive validity of self-efficacy,age and gender was mixed across the investigated ***:This research provided an update on the scarce AID epidemiological *** also supplied evidence about what theoretically-informed measures might be useful targets of interventions in the case of Argentina,Bulgaria,Chile and *** new knowledge of understanding substance abuse determinants and prevalence may help researchers and practitioners better meet young people's health prevention needs.

关键词： Young people Alcohol Ilicit drugs Intention Self-efficacy

Efficiency of a Modular Cleanroom for Space Applications

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Fluid Dynamics & Materials Processing 2024年第3期20卷 547-562页

作者： Matthew R.Coburn Charlie Young Chris Smith Graham Schultz miguel Robayo Zheng-Tong Xie Faculty of Engineering and Physical Sciences University of SouthamptonSouthamptonSO171BJUK Plastron UK Ltd. Westcott Venture ParkWestcottHP180XBUK Renewable Energy Group University of ExeterExeterTR109FEUK

A prototype cleanroom for hazardous testing and handling of satellites prior to launcher encapsulation,satisfying the ISO8 standard has been designed and analyzed in terms of *** Reynolds Averaged Navier-Stokes(URANS)models have been used to study the related flow field and particulate matter(PM)*** outcomes of the URANS models have been validated through comparison with equivalent large-eddy *** attention has been paid to the location and shape of the air intakes and their orientation in space,in order to balance the PM convection and diffusion inside the *** a cyclone-type flow pattern inside the cleanroom is a key to maintaining a high ventilation efficiency.

关键词： Diffuser LES PM RANS unsteady flow exponential decay

Advanced strategies for marine antifouling based on nanomaterial-enhanced functional PDMS coatings

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Nano Materials Science 2024年第4期6卷 375-395页

作者： Xiaohui Shi Hao Wei Wenjun Zhou Paul E.D.Soto rodriguez Cunguo Lin Lei Wang Zhijia Zhang School of Materials Science and Chemical Engineering Harbin Engineering University Qingdao Innovation and Development Center of Harbin Engineering University State Key Laboratory for Marin Corrosion and Protection Luoyang Ship Material Research Institute (LSMRI) Instituto de Estudios Avanzados IUDEA Departamento de Física Universidad de La Laguna C/Astrofísico Francisco Sanchez School of Chemistry and Chemical Engineering Harbin Institute of Technology

Marine biofouling seriously affects human marine exploitation and transportation activities, to which marine antifouling(AF) coatings are considered to be the most cost-effective solution. Since the mid-20th century, human beings have dedicated their efforts on developing AF coatings with long cycle and high performance, leading to a large number of non-target organisms? distortion, death and marine environmental pollution. Polydimethylsiloxane(PDMS), is considered as one of the representative environment-friendly AF materials thanks to its non-toxic, hydrophobic, low surface energy and AF properties. However, PDMS AF coatings are prone to mechanical damage, weak adhesion strength to substrate, and poor static AF effect, which seriously restrict their use in the ocean. The rapid development of various nanomaterials provides an opportunity to enhance and improve the mechanical properties and antifouling properties of PDMS coating by embedding *** on our research background and the problems faced in our laboratory, this article presents an overview of the current progress in the fields of PDMS composite coatings enhanced by different nanomaterials, with the discussion focused on the advantages and main bottlenecks currently encountered in this field. Finally, we propose an outlook, hoping to provide fundamental guidance for the development of marine AF field.

关键词： Nanomaterials Antifouling PDMS composites Environment-friendly Marine biofouling