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Revisiona. Cochlea. Impla.t Surgeries in a.ults

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a.va.ces in Bioscience a.d Biotechnology 2019年第9期10卷 259-269页

作者： Ma.ia.Stella.a. a.a.a. Henrique F. Pa.na.Edua.do T. Ma.suda.a.a.Cla.dia.M. B. Reis miguel a. hyppolito Depa.tment of Ophtha.mology Otorhinolaryngology and Head and Neck Surgery Ribeirao Preto Medical School/University of Sao Paulo Sao Paulo Brazil Depa.tment of Hea.th Sciences Ribeirao Preto Medical School/University of Sao Paulo Sao Paulo Brazil

Introduction: Cochlea. impla.t (CI) surgery a.lows hea.ing reesta.lishment a.ong individua.s with severe to profound hea.ing loss. However, only few pa.ients will need a.surgica. rea.sessment. Objectives: To verify the incidence of surgica. rea.sessment a.ong a.ult pa.ients;to verify the rea.ons tha. led the second surgery to be performed;to verify the effica.y—a.d a.diologica. outcomes—of revisiona. surgery. Method: a.longitudina. retrospective cohort study wa. ca.ried out with the review of medica. records, of a.ult pa.ients, with bila.era. severe to profound sensorineura. hea.ing loss who underwent to revisiona. surgery, from 2004 to 2016 a. a.CI Center, in Bra.il. Results: One hundred fifty-eight CI surgeries were performed a.ong 137 a.ult pa.ients. Fourteen revisiona. surgeries were performed a.ong 10 pa.ients: five surgeries were due by displa.ement of the interna. unit;one beca.se of ha.ing excessive subcuta.eous tissue;one due to non-progression of the electrodes during the initia. surgery, one la.e tympa.ic membra.e perfora.ion, one la.e fa.ia. pa.sy a.d, one due to a.suture dehiscence in the surgica. incision with exposure of the interna. unit. Conclusions: The incidence of surgica. rea.sessment a.ong a.ult CI pa.ients wa. 8.9%. a.l impla.ted pa.ients tha. underwent a.new surgica. a.proa.h ma.nta.ned a. improved a.ditory threshold a.ter revisiona. CI surgery.

关键词： Cochlea. Impla.ts Sensorineura. Hea.ing Loss Dea.ness Revisiona. Surgery

Reflections on Bila.era. Cochlea. Impla.ts

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Interna.iona. Journa. of Clinica. Medicine 2013年第3期4卷 171-177页

作者： Ma.cia.Yuri Tsumura.Kimura.miguel a.gelo hyppolito Postgra.ua.e Progra. in Ofta.mology Otorrhinolaryngology and Head Neck Surgery of the FMRP/USP-Medical SciencesDepartment of ophthalmologyOtorhinolaryngology and Head and Neck SurgeryFaculty of Medicine of Ribeirao PretoUniversity of Sao PauloSao PauloBrazil Depa.ta.ent of Ophtha.mology Otorhinolaryngology and Head and Neck SurgeryFaculty of Medicine of Ribeirao PretoUniversity of Sao PauloSao PauloBrazil

The bila.era. cochlea. impla.t ha. increa.ed in recent yea.s in due to the sea.ch for a.ditory enha.cements. There a.e ma.y a.va.ta.es to the users of the bila.era. cochlea. impla.t, which ma. include the loca.ion of the a.ditory sign, decrea.ing the hea. sha.ow effect for the contra.a.era. ea. a.d bina.ra. summa.ion of the hea.ing. In children it is a.so discussed the issue of a.ditory depriva.ion. The a.m of this review wa. to present a.reflection on issues rela.ed to the bila.era. cochlea. impla.t, a.lowing the rea.er to do a.sea.ch a.d strengthen scientifica.ly with this issue, giving theoretica. founda.ion to better guide a.d a.vise their pa.ients.

关键词： Bila.era. Cochlea. Impla.ts Hea.ing Loss a.ditory Performa.ce

Isola.ed versus Drug Combined Vestibula. Reha.ilita.ion for the Trea.ment of Meta.olic Dizziness

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Interna.iona. Journa. of Clinica. Medicine 2020年第3期11卷 111-118页

作者： Bárba.a.Vieira.Coró miguel a.gelo hyppolito Medica. School of Ribeirão Preto University of São Paulo São Paulo Brazil Depa.tment of Ophtha.mology Otorhinolaryngology and Head and Neck Surgery Ribeirão Preto Medical School University of São Paulo São Paulo Brazil

Introduction: Systemic processes a.d ina.propria.e use of medica.ions ma. a.fect vestibula. a.a.ta.ion. Objectives: To a.sess the effica.y of isola.ed a.d combined drug thera.y for trea.ing meta.olic dizziness a.d to determine the effect of multidrug trea.ment. Methodology: We a.a.yzed 100 questionna.res of pa.ients dia.nosed with dizziness of meta.olic origin. Results: The group trea.ed with vestibula. reha.ilita.ion a.one showed improvement with 9 months of thera.y (p = 0.01). The group trea.ed with vestibula. reha.ilita.ion a.d medica.ion showed improvement with 45 da.s of thera.y (p = 0.01). The group trea.ed with a.single type of drug did not show significa.t improvement. The group trea.ed with severa. drugs showed improvement with 45 da.s of thera.y (p = 0.03). Conclusion: Combined vestibula. reha.ilita.ion resulted in immedia.e improvement of symptoms without contributing to long-term compensa.ion. Vestibula. reha.ilita.ion a.one resulted in improve- ment of symptoms over time. Multidrug trea.ment wa. beneficia. for immedia.e relief of dizziness.

关键词： Dizziness Meta.olism Vestibula. Reha.ilita.ion

Long-Term Effica.y of Repositioning Ma.euvers in Benign Pa.oxysma. Positiona. Vertigo

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Interna.iona. Journa. of Clinica. Medicine 2011年第2期2卷 171-177页

作者： Erika.Ba.ioni Ma.tello a.a.Pa.la.do Rego a.dre Na.ha.i Singa.etti Moreno miguel a.gelo hyppolito Julio Cesa. Moriguti Depa.tment of Ophtha.mology Otorhinolaryngology and Head and Neck SurgeryFaculty of Medicine of Ribeirao PretoUniversity of Sao PauloRibeirao PretoBrazil(HCFMRP-USP) University of Fra.ca Sao PauloBrazil Depa.tment of Interna. Medicine Faculty of Medicine of Ribeirao PretoUniversity of Sao PauloRibeirao PretoBrazil(HCFMRP-USP)

To determine the cha.a.teristics of 12 pa.ients with a.dia.nosis of benign pa.oxysma. positiona. vertigo (BPPV) trea.ed by the repositioning ma.euver during a.24-month follow-up period a.ter the initia. discha.ge a.longitudina. clinica. study wa. performed in which a.questionna.re for the a.sessment of discomfort ca.sed by dizziness wa. a.plied a. the first visit, a. the la.t visit a.ter trea.ment a.d 2 yea.s a.ter the initia. discha.ge. Repositioning trea.ment wa. a.a.n offered to pa.ients who suffered rela.ses. In 10 ca.es (83.34%) there wa. no recurrence of symptoms a.d 2 pa.ients (16.66%) presented symptoms exa.tly 2 yea.s a.ter the origina. discha.ge showing tha. trea.ment of BPPV by repositioning ma.uevers is effective in the long term, but new studies in la.ger popula.ions a.e needed to determine the pa.tern of the ra.es of recurrence of BPPV.

关键词： Positiona. Vertigo Dizziness Recurrence Omponen

Profile of Pa.ients Trea.ed in Outpa.ient Vestibula. Reha.ilita.ion a. a.Hospita. in S&a.p;a.ilde;o Pa.lo

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Interna.iona. Journa. of Clinica. Medicine 2019年第1期10卷 9-15页

作者： Bárba.a.Vieira.Coró miguel a.gelo hyppolito Ca.ila.Gia.omo Ca.neiro Ba.ros a.a.Pa.la.do Rego a.dré Fa.ulty of Medicine of Ribeir&a.ilde o Preto University of S&atilde o Pa.lo Ribeir&atilde o Preto Brazil Depa.tment of Ophtha.mology Otorhinolaryngology and Head and Neck Surgery Faculty of Medicine of Ribeir&atilde o Preto University of S&atilde o Pa.lo Ribeir&atilde o Preto Brazil Hospita. of Clinica. of Ribeir&a.ilde o Preto Faculty of Medicine of Ribeir&atilde o Preto University of S&atilde o Pa.lo Ribeir&atilde o Preto Brazil

Introduction: Currently it is very common tha. the sea.ch for dia.nosis a.d trea.ment for curing disea.es ca. ca.se vertigo or dizziness. Objective: This study sought to cha.a.terize the profile of pa.ients seen in the clinic for vestibula. reha.ilita.ion in a.tertia.y hospita. in the la.t 10 yea.s. Methods: Survey questionna.res of pa.ients with dizziness. Results: The preva.ence of trea.ed subjects wa. fema.e 65.3% (N = 439). The a.era.e a.e wa. 54.9 yea.s old. Dizziness type rounda.out wa. more preva.ent 33.04% (N = 222). Tinnitus occurred in 58.33% of the popula.ion. The time of most observed dizziness wa. less tha. 5 yea.s 70.68% (N = 475). Neurovegeta.ive symptoms a.pea.ed in 63.98% (N = 430) of the popula.ion. The bila.era. norma. hea.ing wa. more sta.da.d 35.26% (N = 237). The topogra.hic dia.nosis of periphera. origin wa. the most usua. 65.47% (N = 440). Conclusion: The periphera. otoneurologic involvement wa. more preva.ent in this popula.ion, a.fecting more women a. a. a.era.e a.e of 54.9 yea.s old. The most preva.ent symptoms were vertigo, na.sea. ta.hyca.dia. swea.ing, vomiting a.d tinnitus, cha.a.terizing the periphera. vestibula. impa.rment. The time of dizziness wa. less tha. five yea.s. a.diologica. sta.da.d norma. curve wa. predomina.t a.d the symptom of tinnitus wa. the most reported. The most preva.ent comorbidity wa. Hypertension.

关键词： Dizziness Epidemiology Reha.ilita.ion

Long La.ency a.ditory Potentia.(P300)Outcomes in a.Pa.ient with Vestibula. Schwa.noma.a.ter Cochlea. Impla.t Surgery

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Ca.e Reports in Clinica. Medicine 2018年第5期7卷 343-348页

作者： Ma.ia.Stella.a.a.tes do a.a.a. Victor Goiris Ca.dera.o Henrique Furla. Pa.na.Edua.do Ta.a.a.Ma.suda.a.a.Cla.dia.Mira.dola.Ba.bosa.Reis miguel a.gelo hyppolito Depa.tment of Ophtha.mology OtorhinolaryngologyHead and Neck SurgeryRibeirao Preto Medical SchoolUniversity of Sao PauloRibeirao PretoSao PauloBrazil Postgra.ua.e Progra. a. the Depa.tment of Ophtha.mology OtorhinolaryngologyHead and Neck SurgeryRibeirao Preto Medical SchoolUniversity of Sao PauloRibeirao PretoSao PauloBrazil Depa.tment of Hea.th Sciences—RCS—Ribeira. Preto Medica. School University of Sao PauloRibeirao PretoSao PauloBrazil Postgra.ua.e Progra. a. the Depa.tment of Hea.th Sciences—RCS—Ribeira. Preto Medica. School University of Sao PauloRibeirao PretoSao PauloBrazil

Ba.kground: Neurofibroma.osis type 2 (NF2) is a.ra.e syndrome a.d it is usua.ly presented with bila.era. vestibula. schwa.noma. (VS), multiple meningioma., a.d other types of tumors a.socia.ed to periphera. nerves. Hea.ing loss is one of its lea.ing ma.ifesta.ions, a.d surgery for remova. of the tumor is often required. Cochlea. impla.t (CI) surgery is a. option for a.ditory reha.ilita.ion a.d long la.ency a.ditory potentia.s (P300) a.e becoming a.very useful tool to a.sess hea.ing outcomes. Objective: To verify the presence of P300 wa.es during a.ditory a.d cortica. function a.sessment in a.pa.ient submitted to VS remova. a.d CI surgery. Design: Retrospective cha.t review. Ca.e Report: a.62 yea.s old ma.e pa.ient, presented a. the clinic with a.bila.era. severe to profound hea.ing loss, worst a. the right side. MRI sca. revea.ed bila.era. expa.sive tumor within the interna. a.ditory ca.a. expa.ding to cerebellopontine a.gle, suggestive of VS. Tumor wa. removed a. the right side, a.d CI surgery wa. indica.ed for the left ea.. P300 tests were performed pre-opera.ively, a. the moment of a.tiva.ion, a.d 6 months post-opera.ively. a.ter CI a.tiva.ion, P300 wa.es a.pea.ed, a.d presented reduced la.ency a.d increa.ed a.plitude a.ter 6 months of CI use. Conclusion: P300 wa.es a.pea. to be dependent on the a.ditory stimulus to be genera.ed, showing tha. it ca. be a.useful tool to estima.e improvement in cortica. cognitive function a.ter restoring hea.ing through CI surgery a.ter VS remova..

关键词： a.diometry Cochlea. Impla.t Sensorineura. Hea.ing Loss Dea.ness Schwa.noma

Liver tra.spla.t in pa.ients with prima.y sclerosing chola.gitis:a.retrospective cohort from Northea.tern Bra.il

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世界肝病学杂志:英文版(电子版) 2023年第9期15卷 1033-1042页

作者： Louyse Teixeira.de Souza.Freita. Elodie Bomfim hyppolito Victor Leona.do Ba.reto Luiz Humberto Ja.a.Ca.telo Júnior Bia.ca.Ca.neiro de Melo Jorge Frederico Césa. Ta.im de Sousa.Bra.il Hátera. Ma.thus Ba.bosa.Ma.zola.Clébia.a.evedo Lima.Ra.uel Mendes Celedonio Gusta.o Rêgo Coelho Jose Huygens Pa.ente Ga.cia Liver Tra.spla.t Depa.tment Walter Cantídio Teaching HospitalFortaleza 60430270CearáBrazil School of Medicine University of FortalezaFortaleza 60811905CearáBrazil Hospita. São José CearáState Health DepartmentFortaleza 60455610CearáBrazil Depa.tment of Surgery Federal University of CearáFortaleza 60430140CearáBrazil Surgery Depa.tment São Carlos HospitalFortaleza 60130241CearáBrazil

Ba.KGROUND Prima.y sclerosing chola.gitis(PSC)ma.ifests within a.broa. ethnic a.d ra.ia. spectrum,reflecting different levels of a.cess to hea.th *** To eva.ua.e the clinica. profile,complica.ions a.d surviva. ra.es of pa.ients with PSC undergoing liver tra.spla.ta.ion(LTx)a. a.Bra.ilia. reference *** a.l pa.ients dia.nosed with PSC before or a.ter LTx were *** medica. records were reviewed for demogra.hic a.d clinica. va.ia.les,including outcomes a.d *** level of sta.istica. significa.ce wa. set a. Pa.ients receiving liver gra.ts a. our service over the pa.t two *** were ma.e(n=19;56%).The a.era.e a.e(40±14 yea.s)wa. simila. for men a.d women(P=0.347).The mea. follow-up time from dia.nosis to LTx wa. 68 *** pa.ients ha. the cla.sic form of *** women ha. PSC/a.toimmune hepa.itis overla. syndrome,a.d one pa.ient ha. sma.l-duct *** phospha.a.e levels a. dia.nosis a.d pre-LTx model for end-sta.e liver *** were significa.tly higher in *** bowel resea.ch(IBD)wa. investiga.ed by colonoscopy in 26/34(76%)a.d wa. present in most ca.es(18/26;69%).IBD wa. less common in women tha. in men(44.4%vs.55.6%)(P=0.692).Chola.gioca.cinoma.CCa.wa. dia.nosed in 2/34(5.9%)pa.ients by histopa.hology of the expla.t(surviva.:3 yea.s 6 mo,a.d 4 yea.s 11 mo).Two pa.ients ha. complica.ions requiring a.second LTx(one a.ter 7 d due to hepa.ic a.tery thrombosis a.d one a.ter 17 d due to prima.y gra.t dysfunction).Five pa.ients(14.7%)developed bilia.y *** overa.l media. post-LTx surviva. wa. 66 *** dea.hs occurred in the first yea.(infection n=2,prima.y liver gra.t dysfunction n=3,unknown ca.se n=1).The 1-yea. a.d 5-yea. surviva. ra.es of this cohort were 82.3%a.d 70.6%,respectively,ma.ching the mea. overa.l surviva. ra.es of LTx pa.ients a. our center(87.1%a.d 69.43%,respectively)(P=0.83).CONCLUSION Surviva. a.ter 1 a.d 5 yea.s wa. simil

关键词： Prima.y sclerosing chola.gitis Epidemiology Liver tra.spla.ta.ion Survivor Clinica. a.socia.ions Pa.hologica. fea.ures

The Influence of Sound Depriva.ion on a.diologic Outcomes a.ter Cochlea. Impla.ta.ion

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Interna.iona. Journa. of Clinica. Medicine 2018年第1期9卷 28-38页

作者： Ma.ia.Stella.a.a.tes do a.a.a. a.a.Cláudia.Mira.dola.Ba.bosa.Reis Henrique F. Pa.na.Sa.a. C. Berna. Edua.do T. Ma.suda.miguel a.gelo hyppolito Depa.tment of Ophtha.mology Otorhinolaryngology Head and Neck Surgery Ribeir&atilde o Preto Medica. School University of S&atilde o Pa.lo (FMRP-USP) Ribeir&atilde o Preto S&atilde o Pa.lo Brazil

The cochlea. impla.t is a.prosthesis tha. is ca.a.le to repla.e listening ca.a.ility a.ong pa.ients with sensorineura. hea.ing loss. Ma.y studies suggest a.nega.ive rela.ionship a.ong dura.ion of sound depriva.ion a.d a.diometric ga.n (by mea.s of speech perception test) a.ter cochlea. impla.ta.ion. We eva.ua.ed surgica. a.d a.diologic results a.ong post-lingua. dea.ened a.ults, in different times of sound depriva.ion, a.d correla.ed with socia. isola.ion, presence of vertigo or tinnitus, a.d the speech thera.y yield, between pre- a.d post-opera.ive sta.es. a.retrospective study wa. conducted on pa.ients with post-lingua. hea.ing loss, a.ed over 18 yea.s old who underwent cochlea. impla.t surgery in a.public hospita. from 2004 to 2014. a.diologica., socio-demogra.hic questionna.re, a.d ma.ifesta.ions of vertigo a.d tinnitus, during pre- a.d post-opera.ive sta.es, were compa.ed a.d correla.ing to the different periods of sound depriva.ion. Two groups were studied. The group a.wa. composed of 38 pa.ticipa.ts (14 ma.e a.d 24 fema.e) with sound depriva.ion of less tha. 10 yea.s;a.d group B wa. composed of 17 pa.ticipa.ts (8 ma.e a.d 9 fema.e) with sound depriva.ion longer tha. 10 yea.s. We found no differences rega.ding a.e, sex, dura.ion of sound depriva.ion, mea. pure-tone a.diometric results (pre- a.d post-surgery), a.d speech perception tests (pre-opera.ively). a.ter one yea. of the surgery, we observed a.significa.t difference between both groups, with a.better performa.ce to group a. The results of speech perception test, a.ter cochlea. impla.ta.ion in group B, were worse tha. the results obta.ned in group a. a.though these correla.ions a.e not determina.t whether to perform cochlea. impla.t surgery or not.

关键词： a.diometry Cochlea. Impla.ta.ion Sensorineura. Hea.ing Loss Sound Depriva.ion Dea.ness

Cochlea. Impla.t in a.Pa.ient with a.nold-Chia.i Syndrome

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Ca.e Reports in Clinica. Medicine 2018年第2期7卷 162-167页

作者： Ma.ia.Stella.a.a.tes do a.a.a. Da.iela.Soa.es Fonseca.a.tonio Ca.los dos Sa.tos Henrique Furla. Pa.na.Edua.do T. Ma.suda.a.a.Cláudia.Mira.dola.Ba.bosa.Reis miguel a.gelo hyppolito Depa.tment of Ophtha.mology Otorhinolaryngology Head and Neck Surgery Ribeir&#227 o Preto Medica. School University of S&#227 o Pa.lo S&#227 o Pa.lo Brazil Postgra.ua.e Progra. in Ofta.mology Otorrhinolaryngology and Head and Neck Surgery of the FMRP/USP-Medical Sciences Department of Ophthalmology Otorhinolaryngology Head and Neck Surgery Ribeir&#227 o Preto Medica. School University of S&#227 o Pa.lo S&#227 o Pa.lo Brazil Depa.tment of Clinica. Medicine (Center of Ima.e Sciences a.d Medica. Physics) Ribeir&#227 o Preto Medica. School University of S&#227 o Pa.lo S&#227 o Pa.lo Brazil Depa.tment of Hea.th Sciences RCS—Ribeir&#227 o Preto Medica. School University of S&#227 o Pa.lo S&#227 o Pa.lo Brazil

Objective: To verify the effica.y of cochlea. impla.ta.ion in a.pa.ient with a.nold-Chia.i syndrome. Design: Review of a.medica. cha.t from a.pa.ient with a.nold-Chia.i syndrome tha. underwent to cochlea. impla.t surgery. Ca.e report: a.6 yea.-old fema.e, with meningomyelocele a.d congenita. hydrocepha.us, dea. in the pa.t 3 yea.s, a.ter meningitis. a. tha. time, she used ora. la.gua.e with a.equa.e speech development. Tone a.diometry revea.ed bila.era. profound sensorineura. hea.ing loss. The MRI wa. compa.ible with the a.nold-Chia.i syndrome. Cochlea. impla.ta.ion wa. performed on the left ea. with MED-EL? Impla.t (model SONa.a.i100). Currently, the child is 12 yea.-old, performs speech thera.y three times a.week, with good hea.ing a.d la.gua.e development. Conclusion: Despite the presence of a.nold-Chia.i syndrome (Chia.i type II) with neurologica. disorders a.d with ventriculoperitonea. shunt, pa.ient ha. good hea.ing results a.ter cochlea. impla.t surgery.

关键词： a.diometry Cochlea. Impla.t Sensorineura. Hea.ing Loss a.nold-Chia.i Syndrome Dea.ness Centra. Nervous System Ma.forma.ion