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Interactions of naturally occurring compounds with antimicrobials

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Journal of Pharmaceutical Analysis 2023年第12期13卷 1452-1470页

作者： Izabela Malczak Anna gajda Department of Pharmacology and Toxicology National Veterinary Research InstitutePartyzantów 5724-100Poland

Antibiotics are among the most often used medications in human healthcare and *** these substances can lead to complications such as increasing antibiotic resistance in bacteria or a toxic effect when administering large *** solve these problems,new solutions in antibacterial therapy are *** use of natural products in medicine has been known for *** of them have antibacterial activity,hence the idea to combine their activity with commercial antibiotics to reduce the latter's *** review presents collected information on natural compounds(terpenes,alkaloids,flavonoids,tannins,sulfoxides,and mycotoxins),of which various drug interactions have been *** of the indicated compounds show synergistic or additive interactions with antibiotics,which suggests their potential for use in antibacterial therapy,reducing the toxicity of the antibiotics used and the risk of further development of bacterial ***,there are also compounds which interact antagonistically,potentially hindering the therapy of bacterial *** on its mechanism of action,each compound can behave differently in combination with different antibiotics and when acting against various bacterial strains.

关键词： Interactions Antimicrobials Natural compounds Antibiotics

狐狸界的“妲己” 赤狐近亲相残究竟为什么？

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环球人文地理 2024年第5期 74-81页

作者：鲨鲨张扬的小强滕洪亮 M.Leonard Photo Marcel Rudolph-gajda Kcapaldo mihiro＿wildlife Zyabich vladk213

因美丽而招致杀身之祸，为生存而近亲相残。狐狸界的妲己——赤狐，到底是祥瑞，还是祸水？从古至今，民间流传的神话传说、志怪传记都少不了狐狸们的身影。早在远古时期，华夏领袖大禹的妻子涂山九尾狐还是正面形象，可随后一个全然相...

因美丽而招致杀身之祸，为生存而近亲相残。狐狸界的妲己——赤狐，到底是祥瑞，还是祸水？从古至今，民间流传的神话传说、志怪传记都少不了狐狸们的身影。早在远古时期，华夏领袖大禹的妻子涂山九尾狐还是正面形象，可随后一个全然相反的狐狸形象诞生——妲己，她的知名度远远超过涂山氏，并在一定程度上定义了狐狸的妖媚概念。

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Recent progress in MgB_(2)superconducting joint technology

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镁合金学报(英文) 2023年第7期11卷 2217-2229页

作者： Hao Liang Dipak Patel Mahboobeh Shahbazi Andrzej Morawski Daniel gajda Matt Rindfleisch Richard Taylor Yusuke Yamauchi Md Shahriar A.Hossain School of Mechanical and Mining Engineering The University of QueenslandSt LuciaQueensland 4072Australia QUT Centre for Materials Science and School of Chemistry and Physics Queensland University of TechnologyBrisbaneQueensland 4001Australia Institute of High Pressure Physics Polish Academy of Sciences(PAS)Sokolowska 29/37Warsaw 01-142Poland Institute of Low Temperature and Structure Research Polish Academy of Sciences(PAS)Okólna 2Wrocław 50-422Poland Hyper Tech Research Inc.539 Industrial Mile RdColumbusOhio 43228USA Applied Superconductivity Laboratory Queensland University of TechnologyBrisbaneQueensland 4001Australia Australian Institute for Bioengineering and Nanotechnology(AIBN) The University of QueenslandSt LuciaQueensland 4072Australia Department of Materials Process Engineering Graduate School of EngineeringNagoya UniversityFuro-choChikusa-kuNagoya 464-8603Japan The Commonwealth Scientific and Industrial Research Organisation(CSIRO) LindfieldNew South Wales 2070Australia

Magnesium diboride(MgB_(2))magnets have the potential to be the next-generation liquid-helium-free magnet for magnetic resonance imaging(MRI)application due to their relatively high superconducting transition temperature,high current density and low raw material cost compared with current commercial niobium-titanium(Nb-Ti)magnets.A typical superconducting magnet includes several *** produce an ultra-stable magnetic field for imaging in MRI,a superconducting electromagnet operating in a persistent mode is *** coils of the electromagnet in MRI are short-circuited to operate in the persistent mode by connecting coils with superconducting ***-sistent joints have been demonstrated for in-situ and ex-situ wires of both mono-and multi-filamentary structures,made predominantly by PIT techniques similar to those used in wire *** realise further engagement of MgB_(2)in MRI applications,enhancing the performance of MgB_(2)superconducting joints is *** literature review summarises research and development on MgB_(2)superconducting joining technology.

关键词： MgB_(2) Superconducting joints Persistent-mode magnets MRI application Field-decay measurement

Managing the Value of the Organization Based on Organizational Culture

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Chinese Business Review 2015年第5期14卷 265-271页

作者： Joanna gajda Czestochowa University of Technology Czestochowa Poland

Managing the value of the organization is taking place based on factors forming it. It is becoming possible thanks to such managing operations of the organization, when in the end an image in accordance with expectations, giving the state back to the value of organizations is being got. Creating the goodwill is based among others on immaterial factors, which although they are becoming impossible to include in balance, are taken hold in time value of the organization. Creation of the value of an organization may be based on the organizational culture. The article presents the essence of value management and organization characterized the factors affecting the formation of organizational culture, ways of dealing with an organization aimed at consolidating and strengthening the organizational culture. Sometimes organizations feel the need to change the culture in order to achieve increased efficiency and ensure the success of the company to implement the necessary changes. Therefore, the rest of this article presents the elements to ensure a smooth implementation and consolidation of cultural change.

关键词： managing the value of the organization the organizational culture managing

Soft-chemistry synthesis of Ba2Ca2Cu3Ox precursor and characterization of high-Tc Hg0.8Pb0.2Ba2Ca2Cu3O8+δsuperconductor

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Journal of Advanced Ceramics 2016年第3期5卷 185-196页

作者： T.BRYLEWSKI K.PRZYBYLSKI A.MORAWSKI D.gajda T.CETNER J.CHMIST AGH University of Science and Technology Faculty of Materials Science and CeramicsAl.Mickiewicza 30 30-059 Krakow Poland Institute of High Pressure Physics of the Polish Academy of Sciences Superconductor Laboratory NL-6ul.Prymasa Tysiqclecia 98 00-893 Warsaw Poland International Laboratory of High Magnetic Fields and Low Temperatures ul.Gajowicka 9553-421 Wroclaw Poland AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceAl.Mickiewicza 30 30-059 Krakow Poland

The paper describes the sol–gel process applied to synthesize a mercury-free Ba2Ca2Cu3O x precursor and the physicochemical properties of an Hg0.8Pb0.2Ba2Ca2Cu3O8+δ ... 详细信息

The paper describes the sol–gel process applied to synthesize a mercury-free Ba2Ca2Cu3O x precursor and the physicochemical properties of an Hg0.8Pb0.2Ba2Ca2Cu3O8+δ high-temperature superconductor (HTS) polycrystalline sample. The Ba2Ca2Cu3O x precursor with desired chemical and phase compositions was obtained using EDTA gel process followed by decomposition and calcination under optimized conditions. An Hg0.8Pb0.2Ba2Ca2Cu3O8+δ superconductor with a fine-grained microstructure, composed predominantly of the (Hg,Pb)-1223 phase in the form of plate-like crystallites or oval grains and with advantageous magnetic properties (T c(on) = 129.2 K, ΔT c = 6.5 K), was synthesized using the high-pressure crystallization method. At 20 K and 1 T, the critical current density of the studied sample was approximately 26 A/mm2, while at 4 K and 1 T it increased to 155 A/mm2. The high volume fraction of the (Hg,Pb)-1223 phase (89.1%) in the high-T c sample was associated with the low value of the average copper valence (2.11) in the calcinated Ba2Ca2Cu3O x precursor. Small amounts of non-superconducting secondary phases—BaCuO2, CaO, CaHgO2, CuO, Ca2CuO, BaPbO3—were also identified within the microstructure of Hg0.8Pb0.2Ba2Ca2Cu3O8+δ .

关键词： superconductor microstructure EDTA gel process secondary phase

Interplay between cold densification and malic acid addition (C4H6O5) for the fabrication of near-isotropic MgB2 conductors for magnet application

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Journal of Magnesium and Alloys 2020年第2期8卷 493-498页

作者： Md.Shahriar A.Hossain Carmine Senatore Yusuke Yamauchi Mislav Mustapic Daniel gajda Dipak Patel Aslam Khan Jung Ho Kim Andrzej J Morawski Rene Flukiger School of Mechanical and Mining Engineering The University of QueenslandBrisbaneQLD 4072Australia Department of Quantum Matter Physics(DQMP) University of GenevaGenevaSwitzerland Key Laboratory of Eco-chemical Engineering College of Chemistry and Molecular EngineeringQingdao University of Science and TechnologyQingdao 266042China School of Chemical Engineering and Australian Institute for Bioengineering and Nanotechnology(AIBN) The University of QueenslandBrisbaneQLD 4072Australia International Center for Materials Nanoarchitectonics(WPI-MANA) National Institute for Materials Science(NIMS)1-1 NamikiTsukubaIbaraki 305-0044Japan University of Osjek Departiment of Physics31000OsijekCroatia Institute of Low Temperature and Structure Research PAS Okolna 250-422 WroclawPoland Research Center for Functional Materials National Institute for Materials Science(NIMS)1-2-1 SengenTsukubaIbaraki 305-0047Japan King Abdullah Institute for Nanotechnology King Saud UniversityRiyadh11451Saudi Arabia Australian Institute for Innovative Materials(AIIM) University of WollongongSquires WayNorth WollongongNSW 2500Australia Institute of High Pressure Physics Polish Academy of Sciences(PAS)Sokoiowska 29/3701-142 WarsawPoland

The effect of cold high pressure densification(CHPD)on anisotropy of the critical current density(Jc)in《in situ》single core binary and alloyed MgB2 tapes has been determined as a function of temperatures at 4.2 K,20 K and 25 K as well as at applied magnetic fields up to 19 *** study includes binary and C4H6O5(malic acid)doped MgB2 tapes before and after *** is remarkable that the CHPD process not only improved the Jc values,in particular at the higher magnetic fields,but also decreased the anisotropy ratio,Г=JC^///JC^⊥In binary MgB2 tapes,the anisotropy factor F increases with higher aspect ratios,even after applying *** malic acid(C4H6O5)doped tapes,however,the application of CHPD leads only to small enhancements ofГ,even for higher aspect *** is attributed to the higher carbon content in the MgB2 filaments,which in turn is a consequence of the reduced chemical reaction path in the densified *** all applied field values,it was found that CHPD processed C4H6O5 doped tapes exhibit an almost isotropic *** constitutes an advantage in view of industrial magnet applications using wires with square or slightly rectangular configuration.

关键词： Magnesium diboride Cold high pressure densification Anisotropy Tapes Critical current density

Dual-polarization wavelength conversion of 16-QAM signals in a single silicon waveguide with a lateral p-i-n diode[Invited]

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Photonics Research 2018年第5期6卷 I0048-I0054页

作者： FRANCESCO DA Ros ANDRZEJ gajda ERIK LIEBIG EDSON P.DA SILVA ANNA PECZEK PETER D.GIROUARD ANDREAS MAI KLAUS PETERMANN LARS ZIMMERMANN MICHAEL GALILI LEIF K.OXENLOWE DTU Fotonik Technical University of DenmarkDK-2800 Kongens LyngbyDenmark IHP Im Technologiepark 2515236 Frankfurt(Oder)Germany IHP Solutions GmbH Im Technologiepark 2515236 Frankfurt(Oder)Germany Institut for Hochfrequenz-und Halbleiter-Systemtechnologien TU BerlinEinsteinufer 2510587 BerlinGermany AMETEK CTS Europe GmbH L unener StraBe 211-21259174 KamenGermany

A polarization-diversity loop with a silicon waveguide with a lateral p-i-n diode as a nonlinear medium is used to realize polarization insensitive four-wave mixing. Wavelength conversion of seven dual-polarization 16-quadrature amplitude modulation(QAM) signals at 16 GBd is demonstrated with an optical signal-to-noise ratio penalty below 0.7 dB. High-quality converted signals are generated thanks to the low polarization dependence(≤0.5 dB) and the high conversion efficiency(CE) achievable. The strong Kerr nonlinearity in silicon and the decrease of detrimental free-carrier absorption due to the reverse-biased p-i-n diode are key in ensuring high CE levels.

关键词： Invited Dual-polarization wavelength conversion of 16-QAM signals in a single silicon waveguide with a lateral p-i-n diode QAM

动态MRI的计算机辅助分析用于反映浸润型乳腺癌的病理组织学

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国际医学放射学杂志 2010年第5期 493-494页

作者： P.A.T.Baltzer T.Vag M.Dietzel S.Beger C.Freiberg M.gajda 杨卉 Institute of Diagnostic and Interventional Radiology Friedrich Schiller University of JenaErlanger Aller 101

关键词：乳腺肿瘤 MRI DCE-MRI 计算机辅助诊断

5脂氧酶活化蛋白抑制剂MK-886减轻载脂蛋白E/低密度脂蛋白受体双敲除鼠的动脉粥样硬化

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中国动脉硬化杂志 2006年第3期14卷 257-257页

作者： Jawien J gajda M Rudling M Mateuszuk L Olszanecki R Guzik TJ 柯丽琴

最近研究指出,白细胞三烯在动脉粥样硬化中起重要作用。白细胞三烯是由5脂氧酶和5脂氧酶活化蛋白(five lipoxygenase activating protein,PLAP)相互作用形成的。由此推测,FLAP抑制剂MK-886可能在致动脉粥样硬化性载脂蛋白E-低密度脂蛋... 详细信息

最近研究指出,白细胞三烯在动脉粥样硬化中起重要作用。白细胞三烯是由5脂氧酶和5脂氧酶活化蛋白(five lipoxygenase activating protein,PLAP)相互作用形成的。由此推测,FLAP抑制剂MK-886可能在致动脉粥样硬化性载脂蛋白E-低密度脂蛋白受体双敲除小鼠模型中延缓动脉粥样硬化进展。[第一段]

关键词：动脉粥样硬化性低密度脂蛋白受体载脂蛋白E 蛋白抑制剂脂氧酶酶活化 protein 白细胞三烯除鼠减轻