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Effects of laying on of hands with and without a spiritual context on pain and functionality of older women with knee osteoarthritis:study protocol for a randomized controlled trial

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Journal of Integrative Medicine 2018年第2期16卷 106-112页

作者： Katy andrade Monteiro Zacaron Nélia da Silva Mendes Yuri Cotta e Silva Giancarlo Lucchetti School of Medicine Federal University of Juiz de ForaJuiz de Fora 36036-330Brazil Institute of Life Sciences Department of PhysiotherapyFederal University of Juiz de ForaGovernador Valadares 35012-140Brazil Faculty of Physical Therapy Federal University of Juiz de ForaJuiz de Fora 36036-330Brazil

Background： Laying on of hands （LooH） is a culturally-accepted therapy in several traditions. In Brazil, ＂Spiritism＂（third-largest religious tradition in number of followers） uses LooH with the name of ＂Spiritist Passe＂（SP）. However, there are few studies assessing SP＇s role in medical outcomes. The present study aims to investigate the effects of LooH, with and without a spiritual context, on pain, joint stiffness, and functional capacity of older women （≥60 years old） with knee osteoarthritis （KOA）. Methods/design： In this triple-blind, prospective randomized controlled trial, older women with KOA are assigned to three groups： LooH with a spiritual context group, LooH group without a spiritual context, and a control group receiving no intervention. Patients are assessed by a blinded researcher at baseline, 8 weeks, and 16 weeks. Pain, joint stiffness, and functional capacity are assessed using Western Ontario and McMaster Universities Osteoarthritis Index. Other measures such as anxiety, depression, gait speed, and quality of life will also be assessed. To detect differences between groups, a post-intervention com- parison between the three groups and a mean change （post-pre） comparison among the three groups will be done using analysis of variance. All statistical analyses will be performed using an intention-to-treat approach and a per-protocol analysis. Discussion： A pragmatic design using SP, LooH without spiritual context, and no LooH may provide further scientific evidence on SP＇s feasibility and efficacy for KOA patients.

关键词： Complementary therapies Spiritual therapies Therapeutic touch Spiritual healing Holistic therapies Knee osteoarthritis

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Transcatheter Device Closure of a Perimembranous Ventricular Septal Defect in Congenitally Corrected Transposition of the Great Arteries

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Congenital Heart Disease 2022年第2期17卷 193-199页

作者： Catherine E.Tomasulo Lindsay S.Rogers Lauren andrade Michael LO’Byrne Division of Cardiology The Children’s Hospital of PhiladelphiaPhiladelphiaUSA Division of Cardiology Hospital of the University of PennsylvaniaPhiladelphiaUSA Center for Pediatric Clinical Effectiveness The Children’s Hospital of PhiladelphiaPhiladelphiaUSA Leonard Davis Institute and Center for Cardiovascular Outcomes Qualityand Evaluative ResearchUniversity of PennsylvaniaPhiladelphiaUSA

The majority of patients with congenitally corrected transposition of the great arteries,also known as transposition of the great arteries{S,L,L}have ventricular septal defects(VSD),most commonly perimembranous VSD(pmVSD).Transcatheter device closure of pmVSD in these patients has not been widely *** present a case of device closure of pmVSD in L-TGA with an Amplatzer Duct Occluder II(ADOII)device using a deployment starting in the subpulmonary left *** case demonstrates some of the technical advantages of the ADOII device for VSD closure,specifically its low profile,symmetric shape,and soft *** characteristics are advantageous in closing conventional pmVSD but are especially useful in patients with challenging anatomic substrates.

关键词： Percutaneous catheterization congenital heart disease thromboembolism

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Publishing NextGEOSS data on the GEOSS Platform

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Big Earth Data 2023年第2期7卷 413-427页

作者： Roberto Roncella Enrico Boldrini Mattia Santoro Paolo Mazzetti João andrade Nuno Catarino Stefano Nativi National Research Council of Italy Institute of Atmospheric Pollution ResearchDivision of FlorenceFlorenceItaly Deimos Engenharia Avenida Columbano BordaloPinheiroLisbonPortugal

This paper is the second of a series that describes some of the main dataset resources presently shared through the GEOSS Platform. The GEOSS Platform was created as the technological tool to implement interoperability among the Global Earth Observation System of Systems (GEOSS);it is a brokering infrastructure that presently brokers more than 190 autonomous data catalogs and information systems. This paper is focused on the analysis of the NextGEOSS datasets describing the data publishing process from NextGEOSS to the GEOSS platform. In particular, both the administrative registration and the technical registration were taken into consideration. One of the most important data shared by the GEOSS Platform are the NextGEOSS datasets: the present study provides some insights in terms of GEOSS user searches for NextGEOSS data.

关键词： Earth observation GEOSS data interoperability data sharing data brokering services

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Retrospective self-reported weight changes during childhood and adolescence are not good predictors of metabolic syndrome risk factors in Mexican young adults

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Open Journal of Preventive Medicine 2013年第8期3卷 479-486页

作者： Flávia C. D. andrade michelle Jiménez Marcela Raffaelli Margarita Teran-García Celia Aradillas-García Department of Food Sciences and Human Nutrition University of Illinois at Urbana-Champaign Urbana USA Department of Human and Community Development University of Illinois at Urbana-Champaign Urbana USA Department of Kinesiology and Community Health University of Illinois at Urbana-Champaign Urbana USA Faculty of Medicine University Autonomous of San Luis Potosí San Luis Potosí Mexico

The purpose of the study was to examine whether retrospective self-reported weight changes during childhood and adolescence were associated with metabolic syndrome (MetS) risk factors in Mexican young adults. Mexican college applicants to the Universidad Autónoma de San Luis Potosí, Mexico, 18 to 25 years old (n = 4187) who had applied for the 2009 academic year were included in the study. Participants underwent a health screening—anthropometrics and blood drawn—and completed a questionnaire. Five major weight change categories were defined based on self-reported weight during childhood and adolescence: consistently normal, consistently underweight, consistently overweight/ obese, weight gain, and weight loss. Most participants self-reported being normal weight during childhood (58.7%) and adolescence (58.3%). Only a small proportion reported being overweight or obese during childhood (10.1%) or adolescence (15.9%). Weight change patterns during childhood and adolescence were marked by overall stability: 40.1% of participants were consistently normal, 15.6% underweight and 3.6% overweight/obese. Among those whose weight changed, 25.0% gained weight and 15.7% lost weight. In regression analyses, weight change categories based on self-reported weight statuses during childhood and adolescence were not associated with current metabolic syndrome risk factors after controlling for measured current BMI. Studies addressing the association between weight gains in early life with metabolic syndrome outcomes in early adulthood should not rely on recalled weight status during early life alone.

关键词： Weight Change Metabolic Syndrome Metabolic Risk Factors’ Mexican Young Adults

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Inductive Model Generation for Text Classification Using a Bipartite Heterogeneous Network

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Journal of Computer Science & Technology 2014年第3期29卷 361-375页

作者： Rafael Geraldeli Rossi Alneu de andrade Lopes Thiago de Paulo Faleiros Solange Oliveira Rezende Institute of Mathematics and Computer Science University of So PauloSo CarlosBrasil

Algorithms for numeric data classification have been applied for text classification. Usually the vector space model is used to represent text collections. The characteristics of this representation such as sparsity and high dimensionality sometimes impair the quality of general-purpose classifiers. Networks can be used to represent text collections, avoiding the high sparsity and allowing to model relationships among different objects that compose a text collection. Such network- based representations can improve the quality of the classification results. One of the simplest ways to represent textual collections by a network is through a bipartite heterogeneous network, which is composed of objects that represent the documents connected to objects that represent the terms. Heterogeneous bipartite networks do not require computation of similarities or relations among the objects and can be used to model any type of text collection. Due to the advantages of representing text collections through bipartite heterogeneous networks, in this article we present a text classifier which builds a classification model using the structure of a bipartite heterogeneous network. Such an algorithm, referred to as IMBHN （Inductive Model Based on Bipartite Heterogeneous Network）, induces a classification model assigning weights to objects that represent the terms for each class of the text collection. An empirical evaluation using a large amount of text collections from different domains shows that the proposed IMBHN algorithm produces significantly better results than k-NN, C4.5, SVM, and Naive Bayes algorithms.

关键词： heterogeneous network text classification inductive model generation

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Fluid flow simulation of industrial fixed bed mixed-flow grain dryer using k-ω SST turbulence model

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International Journal of Agricultural and Biological Engineering 2021年第2期14卷 226-230页

作者： Anderson Rodrigo Visconcini Cid Marcos Gonçalves andrade Alexandre Marconi de Souza Costa Post-graduation Department of Mechanical Engineering University of MaringáAv.Colombo3790-Bloco 14-Sala 2487020-900Maringá-PRBrazil

The fluid dynamics analysis on industrial,mixed-flow grain dryers with fixed bed using computational techniques is necessary to assist the design of such equipment contributing to cost reduction in the dryer projects and agricultural drying operations that involve the production of grains in the *** study presents a Computational Fluid Dynamic(CFD)solution for air flow analysis in an industrial *** air flow at the inlet and outlet of the dryer was investigated using the k-ωSST turbulence *** dryer region with soybean was considered as a laminar porous medium flow in the permanent and isothermal regime,having for the model a simplified geometry with the tower considered as a porous medium and the air inlet and outlet as a turbulent fluid *** flow was treated with a permanent and isothermal *** flow and pressures were used according to design *** validate the k-ωSST turbulence model,the velocity profile at the dryer inlet was obtained experimentally,which presented results with good agreement between the numerical and the experimental *** model obtained satisfactory results of the computational validation of the air flow in the dryer with good convergence requiring a minimum of computational effort,being suitable for the simulation of industrial-scale dryers,as to its air flow through a tower,operating with fixed bed soybean in the steady and isothermal regime.

关键词： computational methods fixed bed porous medium soybean dryer turbulent flow

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Fecal marker levels as predictors of need for endoscopic balloon dilation in Crohn's disease patients with anastomotic strictures

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World Journal of Gastroenterology 2017年第35期23卷 6482-6490页

作者： Susana Lopes Patrícia andrade Eduardo Rodrigues-Pinto Joana Afonso Guilherme Macedo Fernando Magro Gastroenterology Department Faculty of MedicineHospital de Sao Joao Department of Pharmacology and Therapeutics University of Porto

AIM To evaluate the accuracy and best cut-off value of fecal calprotectin(FC) and fecal lactoferrin(FL) to predict disease recurrence in asymptomatic patients presenting with anastomotic strictures. METHODS This was a longitudinal single tertiary center study based on prospectively collected data(recorded in a clinical database created for this purpose) performed between March 2010 and November 2014. Crohn's disease(CD) patients with anastomotic stricture who submitted to postoperative endoscopic evaluation were included. Stools were collected on the day before bowel cleaning for FC and FL. Endoscopic balloon dilation(EBD) was performed if the patient presented an anastomotic stricture not traversed by the colonoscope, regardless of patients' symptoms. Successful dilation was defined as passage of the colonoscope through the dilated stricture into the neotermimal *** recurrence was defined as a modified Rutgeerts score of ≥ i2 b. RESULTS In a total of 178 patients who underwent colonoscopy, 58 presented an anastomotic stricture, 86% were asymptomatic, and 48(54% male; median age of 46.5 years) were successfully dilated. Immediate success rate was 92% and no complications were recorded. FC and FL levels correlated significantly with endoscopic recurrence(P < 0.001) with an optimal cut-off value of 90.85 μg/g(sensitivity of 95.5%, specificity of 69.2%, positive predictive value(PPV) of 72.4%, negative predictive value(NPV) of 94.7% and accuracy of 81%] for FC and of 5.6 μg/g(sensitivity of 77.3%, specificity of 69.2%, PPV of 68%, NPV of 78.4% and accuracy of 72.9%) for *** Fecal markers are good predictors of CD endoscopic recurrence in patients with asymptomatic anastomotic stricture. FC and FL may guide the need for EBD in this context.

关键词： Crohn's disease Anastomotic strictures Endoscopic balloon dilation Fecal markers Po stoperative recurrence

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Surface processing for iron-based degradable alloys:A preliminary study on the importance of acid pickling

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Bioactive Materials 2022年第5期7卷 166-180页

作者： Leticia Marin de andrade Carlo Paternoster Pascale Chevallier Sofia Gambaro Paolo Mengucci Diego Mantovani Laboratory for Biomaterials and Bioengineering Canada Research Chair I in Biomaterials and Bioengineering for the Innovation in SurgeryDepartment of Min-Met-Materials EngineeringResearch Center of CHU de QuebecDivision of Regenerative MedicineLaval UniversityQuebec CityQCG1V 0A6Canada National Research Council Institute of Condensed Matter Chemistry and Technologies for Energy CNR-ICMATEGenoa16149Italy Polytechnic University of Marche Ancona60121Italy

The formation of a heterogeneous oxidized layer,also called scale,on metallic surfaces is widely recognized as a rapid manufacturing event for metals and their *** or total removal of the scale represents a mandatory integrated step for the industrial fabrication processes of medical *** biodegradable metals,acid pickling has already been reported as a preliminary surface preparation given further processes,such as ***,biodegradable medical prototypes presented discrepancies concerning acid pickling studies based on samples with less complex geometry(e.g.,non-uniform scale removal and rougher surface).Indeed,this translational knowledge lacks a detailed investigation on this process,deep characterization of treated surfaces properties,as well as a comprehensive discussion of the involved *** this study,the effects of different acidic media(HCl,HNO_(3),H_(3)PO_(4),CH_(3)COOH,H_(2)SO_(4) and HF),maintained at different temperatures(21 and 60℃)for various exposition time(15-240 s),on the chemical composition and surface properties of a Fe-13Mn-1.2C biodegradable alloy were *** in mass loss,morphology and wettability evidenced the combined effect of temperature and time for all *** in HCl and HF solutions favor mass loss(0.03-0.1 g/cm^(2))and effectively remove the initial scale.

关键词： Biodegradable metals Iron-based alloys Acid pickling Surface finishing Pre-treatment

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Assembly of IMPDH2-Based,CTPS-Based,and Mixed Rod/Ring Structures Is Dependent on Cell Type and Conditions of Induction

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Journal of Genetics and Genomics 2015年第6期42卷 287-299页

作者： Gerson Dierley Keppeke S.John Calise Edward K.L.Chan Luis Eduardo C.andrade Rheumatology Division Federal University of Sao Paulo Department of Oral Biology University of Florida Immunology Division Fleury Medicine and Health Laboratories

Inhibition of guanosine triphosphate（GTP） and cytidine triphosphate（CTP） biosynthetic pathways induces cells to assemble rod/ring（RR） structures,also named cytoophidia,which consist of the enzymes cytidine triphosphate synthase（CTPS） and inosine-50-monophosphate dehydrogenase 2（IMPDH2）.We aim to explore the interaction of CTPS and IMPDH2 in the generation of RR *** La and COS-7 cells were cultured in normal conditions or in the presence of 6-diazo-5-oxo-L-norleucine（DON）,ribavirin,or mycophenolic acid（MPA）.Over 90% of DON-treated cells presented RR *** He La cells,35% of the RR structures were positive for IMPDH2 alone,26% were CTPS alone,and 31% were IMPDH2/CTPS mixed,while in COS-7 cells,42% of RR were IMPDH2 alone,41% were CTPS alone,and 10% were IMPDH2/CTPS *** and MPA treatments induced only IMPDH2-based *** were also transfected with an N-terminal hemagglutinin（NHA）-tagged CTPS1 *** 95% of NHA-CTPS1 transfected cells with DON treatment presented IMPDH2-based RR and almost 100% presented CTPS1-based RR;when treated with ribavirin,over 94% of transfected cells presented IMPDH2-based RR and 37% presented CTPS1-based RR,whereas 2% of untreated transfected cells presented IMPDH2-based RR and 28% presented CTPS1-based *** results may help in understanding the relationship between CTP and GTP biosynthetic pathways,especially concerning the formation of filamentous RR structures.

关键词： Nucleotide synthesis Enzyme aggregation Enzyme inhibition IMPDH2 CTPS

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Response to Commentary by Dr. Matthew J. Clarkson on

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Journal of Sport and Health Science 2024年第5期13卷 670-671页

作者： Hugo de Luca Corrêa Lysleine Alves Deus Dahan da Cunha Nascimento Nicholas Rolnick Rodrigo Vanerson Passos Neves Andrea Lucena Reis Thais Branquinho de Araújo Carmen Tzanno-Martins Fernanda Silveira Tavares Luiz Sinésio Silva Neto Cláudio Avelino Rodrigues Santos Paolo Lucas Rodrigues-Silva Fernando Honorato Souza Vitória Marra da Motta Vilalva Mestrinho Rafael Lavarini dos Santos Rosangela Vieira andrade Jonato Prestes Thiago dos Santos Rosa Post-graduate Program of Physical Education Catholic University of BrasıliaBrasılia 71966-700Brazil The Human Performance Mechanic Lehman CollegeNew YorkNY 10011USA Clinical Group Home Dialysis Center and RenalClass Sao Paulo 01239-040Brazil Department of Medicine Catholic University of BrasıliaBrasılia 71966-700Brazil Faculty of Medicine Federal University of TocantinsTocantins 77001-090Brazil Embrapa Genetic Resources and Biotechnology Brasılia 70770-917Brazil g Graduate Program of Genomic Sciences and Biotechnology Brasılia 71966-700Brazil

Dear editor:We sincerely thank Matthew *** for his insightful commentary1 on our recent publication in the Journal of Sport and Health Science.2 Clarkson's pioneering work in the development and application of blood flow restriction (BFR) exercise protocols has undeniably laid the groundwork for subsequent investigations in this field,including our own.(3-6)His commentary not only highlights the relevance and timeliness of our study but also offers valuable perspectives on refining safety considerations for intradialytic BFR exercise among hemodialysis patients.

关键词： patients application flow

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