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Prevalence of Depression and Anxiety in Patients with Autoimmune Disease: A Comparative Study with a Diabetic Population

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Open Journal of Internal medicine 2024年第2期14卷 159-166页

作者： michel Assane Ndour mouhamed Dieng Omar Boun Khatab Diouf Léon Birwe Boundia Djiba Ibrahima mané Diallo matar Ndiaye Nousradine mourno Tarsa Djiby Sow Anna Sarr Demba Diedhiou maimouna Ndour mbaye Service de mdecine Interne Centre Hospitalier Abass Ndao Dakar Senegal Service de mdecine Interne Centre Hospitalier Aristide Le Dantec Dakar Senegal

Introduction: Systemic diseases are a variety of heterogeneous autoimmune and/or autoinflammatory diseases and syndromes usually affecting multiple systems and resulting from immune system dysregulation. we evaluated risk factors for depression and anxiety in an autoimmune disease cohort compared with diabetic patients. Patients and methods: we conducted an observational, cross-sectional, case-control survey comparing two groups: individuals with connective tissue disease (CTD) and diabetic controls who were followed within three Dakar University hospitals during the period from April to June 2023. Results: The sample comprised 106 participants, of whom 51 (48%) had CTD and 55 (52%) served as diabetic controls. In the CTD group, the majority had lupus (19) and rheumatoid arthritis (23). The CTD patients had a mean age of 41.0 years (SD 16.9), while the diabetic patients had a mean age of 55.9 years (SD 11.7), with a significant difference observed (p Conclusion: Compared to a chronic disease, devastating in Africa and evolving over the long term, autoimmune diseases are more strongly and more frequently associated with anxiety and depression. This is a factor to be taken into account in the holistic management of these patients.

关键词： Connective Tissue Disease Lupus Rhumatoid Arthritis Diabetes Depression Anxiety Disability

Seismic vulnerability evaluation of axially loaded steel built-up laced members II:evaluations

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Earthquake Engineering and Engineering Vibration 2008年第2期7卷 125-136页

作者： Kangmin Lee michel Bruneau Department of Architectural Engineering Chungnam National University Department of Civil Structuraland Environmental EngineeringUniversity at BuffaloState University of New York

The test results described in Part 1 of this paper （Lee and Bruneau, 2008） on twelve steel built-up laced members （BLms） subjected to quasi-static loading are analyzed to provide better knowledge on their seismic behavior. Strength capacity of the BLm specimens is correlated with the strength predicted by the AISC LRFD Specifications. Assessments of hysteretic properties such as ductility capacity, energy dissipation capacity, and strength degradation after buckling of the specimen are performed. The compressive strength of BLms is found to be relatively well predicted by the AISC LRFD Specifications. BLms with smaller kl/r were ductile but failed to reach the target ductility of 3.0 before starting to fracture, while those with larger kl/r could meet the ductility demand in most cases. The normalized energy dissipation ratio, EC/ET and the normalized compressive strength degradation, Cr″/Cr of BLms typically decrease as normalized displacements δ/δb,exp increase, and the ratios for specimens with larger kl/r dropped more rapidly than for specimens with smaller kl/r; similar trends were observed for the monolithic braces. The BLms with a smaller slenderness ratio, kl/r, and width-to-thickness ratio, b/t, experienced a larger number of inelastic cycles than those with larger ratios.

关键词： seismic vulnerability built-up compression member strength capacity ductility capacity energy dissipation strength degradation

Profile of Extra-Pulmonary Tuberculosis in Internal medicine

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Open Journal of Internal medicine 2024年第1期14卷 64-73页

作者： mouhamed Dieng Djiby Sow Demba Diédhiou michel Assane Ndour Boundia Djiba mouhamed Almahy Niang matar Ndiaye Oumar Boun Khattab Diouf Fatou Kiné Gadji Anna Sar maïmouna Ndour mbaye Clinique médicale II H&ocircpital Aristide Abass Ndao Université Cheikh Anta Diop Dakar Sénégal

Introduction: Tuberculosis is an infectious disease that mainly affects the lung. Extrapulmonary localizations are a reason for hospitalization in our health facilities. The objective of this study was to describe the epidemiological, clinical, paraclinical and evolutionary aspects of extra pulmonary tuberculosis (EPT) at the Abass Ndao Hospital Center. Patients and methods: This was a descriptive cross-sectional study conducted over a period of 11 years (January 1, 2010 to December 30, 2021). All patients with extrapulmonary tuberculosis hospitalized in the department of internal medicine during the recruitment period were included. Results: Fifty-two (52) patients were collected. The year 2019 recorded the most cases 23.08% (n = 20). The mean age of the patients was 40.56 ± 18.24 years. The age group 20 - 34 years 42.31% (n = 22) was the most represented. Females were in the majority 61.54% (n = 32) with a sex ratio (m/F) was 0.63. Housewives were in the majority 40.38% (n = 21). 60.87% of the cases (n = 14) came from a health facility. 38.46% of the cases had been infected. 21.74% (n = 9) were smokers. The reasons for consultation were dominated by fever (67.44%), AEG (62.79%) and cough (41.86%). Eighteen patients (40.91%) had fever. The mean time to consultation was 77.37 ± 90.3 days with extremes of 3 and 365 days. The median was 45 days. more than half of the patients 61.90% (n = 26) had anemia. Positive retroviral serology was noted in 21.43% of cases. All patients had a CRP greater than 6. more than half of the patients 51.92% (n = 27) had multifocal tuberculosis. The peritoneum 44.23% (n = 23) was the main organ affected. The average hospital stay was 9.8 ± 4.9 days with extremes of 1 and 19 days. All patients had received the protocol in force at the national level. Death was noted in 4 patients (9.52%). Conclusion: EPT is characterized in our context by a notorious diagnostic difficulty due to the multiplicity of clinical presentations, the complexity of

关键词： Extrapulmonary Tuberculosis Epidemiology Diagnosis Senegal

雄高尔《圣安东尼的磨难》——其图像学以及对德国艺术的影响

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美术 2024年第9期 122-135页

作者： [法]让·米歇尔·马桑赵津(译) 赵成清(译) 剑桥大学艺术史系中央民族大学四川大学艺术学院

德国画家、雕塑家雄高尔的《圣安东尼的磨难》是描绘圣安东尼被恶魔攻击的经典作品,其创作灵感源自《安东尼传》中关于圣安东尼的描述。通过将圣安东尼置于空中受恶魔攻击的场景,雄高尔成功展现了圣徒的冷静与从容。该作品对后世德国、... 详细信息

德国画家、雕塑家雄高尔的《圣安东尼的磨难》是描绘圣安东尼被恶魔攻击的经典作品,其创作灵感源自《安东尼传》中关于圣安东尼的描述。通过将圣安东尼置于空中受恶魔攻击的场景,雄高尔成功展现了圣徒的冷静与从容。该作品对后世德国、意大利等地的艺术家产生了深远影响。本文通过详细分析雄高尔的版画风格、恶魔形象以及与其他艺术作品的关联,探讨其在恶魔图式发展中的独特贡献。

关键词：雄高尔圣安东尼的磨难恶魔图式德国艺术

Ahlfors-regular curves and Carleson measures

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Science China mathematics 2020年第6期63卷 1057-1064页

作者： Huaying wei michel Zinsmeister Department of mathematics and Statistics Jiangsu Normal UniversityXuzhou 21116China IDP Universite d'OrleansOrleans 45067France

we study the relation between the boundary of a simply connected domainΩbeing Ahlfors-regular and the invariance of Carleson measures under the push-forward operator induced by a conformal mapping from the unit disk△onto the domainΩ.As an application,we characterize the chord-arc curves with small norms and the asymptotically smooth curves in terms of the complex dilatation of some quasiconformal reflection with respect to the curve.

关键词： Ahlfors-regular curve Carleson measure push-forward operator chord-arc curve asymptotically smooth curve

Simulation of unconventional well tests with the finite volume method

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Petroleum Science 2012年第3期9卷 317-329页

作者： CANCELLIERE michel VERGA Francesca Politecnico di Torino DITAGTorino (TO) 10129 Italy

The finite volume method has been successfully applied in several engineering fields and has shown outstanding performance in fluid dynamics simulation. In this paper, the general framework for the simulation ofnear-wellbore systems using the finite volume method is described. The mathematical model and the numerical model developed by the authors are presented and discussed. A radial geometry in the vertical plane was implemented so as to thoroughly describe near-wellbore phenomena. The model was then used to simulate injection tests in an oil reservoir through a horizontal well and proved very powerful to correctly reproduce the transient pressure behavior. The reason for this is the robustness of the method, which is independent of the gridding options because the discretization is performed in the physical space. The model is able to describe the phenomena taking place in the reservoir even in complex situations, i.e. in the presence of heterogeneities and permeability barriers, demonstrating the flexibility of the finite volume method when simulating non-conventional tests. The results are presented in comparison with those obtained with the finite difference numerical approach and with analytical methods, if possible.

关键词： Finite volume method numerical methods horizontal well modeling injection testing gridding

A comparative study of the sorption of O-PAHs and PAHs onto soils to understand their transport in soils and groundwater

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Journal of Environmental Sciences 2023年第2期124卷 61-75页

作者： w.Almouallem J.michel S.Dorge C.Joyeux G.Trouve D.Le Nouen French National Institute for Industrial and Environment and Risks Direction Sites&TerritoiresVerneuil en HalatteF-60550France University of Haute-Alsace Laboratoire Gestion des Risques et Environnement(LGRE)UR2334MulhouseFrance University of Strasbourg 67000 StrasbourgFrance University of Haute-Alsace Laboratoire d’Innovation Moléculaire et Applications(LIMA)UMR 7042 CNRSMulhouseFrance

Polycyclic aromatic hydrocarbons(PAHs)and their oxygenated derivates(O-PAHs)are identified in soils and groundwater of industrialized sites and contribute to the risk for Humans and the ***,data are scarce in literature concerning their retention and transfer in soils and no soil-water partition coefficients are available for these *** of two PAHs,fluorene and acenaphthene and two O-PAHs,9H-fluorenone and dibenzofuran onto two soils with different organic carbon contents was evaluated and compared by determining their sorption *** of ionic strength and liquid to solid ratio,on fluorene and fluorenone sorption was also *** equilibrium is achieved within less than 24 hr of mixing and linear sorption models best fit the isotherm *** and dibenzofuran are similarly sorbed onto the *** of fluorene is higher than the one of fluorenone,showing a smaller affinity of fluorenone towards the solid *** means that O-PAH could form larger contamination plumes in groundwater than *** the L/S ratio from 100 to 50 and 30,increases the sorption of fluorenone onto the soil by 56% and 67%respectively,while the sorption of fluorene is slightly *** the ionic strength of the aqueous phase also modifies the sorption of fluorenone,contrary to the sorption of fluorene which is slightly affected.

关键词： PAHs O-PAHs Contaminated soils Groundwater Sorption Kinetics Isotherms

Enhanced Userspace and In-Kernel Trace Filtering for Production Systems

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Journal of Computer Science & Technology 2016年第6期31卷 1161-1178页

作者： Suchakrapani Datt Sharma michel Dagenais Department of Computer and Software Engineering Ecole Polytechnique de Montrdal Montreal H3T 1J4 Canada

Trace tools like LTTng have a very low impact on the traced software as compared with traditional debuggers. However, for long runs, in resource constrained and high throughput environments, such as embedded network switching nodes and production servers, the collective tracing impact on the target software adds up considerably. The overhead is not just in terms of execution time but also in terms of the huge amount of data to be stored, processed and analyzed offiine. This paper presents a novel way of dealing with such huge trace data generation by introducing a Just-In-Time （JIT） filter based tracing system, for sieving through the flood of high frequency events, and recording only those that are relevant, when a specific condition is met. with a tiny filtering cost, the user can filter out most events and focus only on the events of interest. we show that in certain scenarios, the JIT compiled filters prove to be three times more effective than similar interpreted filters. we also show that with the increasing number of filter predicates and context variables, the benefits of JIT compilation increase with some JIT compiled filters being even three times faster than their interpreted counterparts. we further present a new architecture, using our filtering system, which can enable co-operative tracing between kernel and process tracing Vms （virtual machines） that share data efficiently. we demonstrate its use through a tracing scenario where the user can dynamically specify syscall latency through the userspace tracing Vm whose effect is reflected in tracing decisions made by the kernel tracing Vm. we compare the data access performance on our shared memory system and show an almost 100 times improvement over traditional data sharing for co-operative tracing.

关键词： tracing debugging filtering operating system interpreter

Some questions about landscape modelling

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Journal of Environmental Sciences 2001年第4期13卷 459-465页

作者： michel Godron LI Xiu-zhen CCAS F18410BrinonFrance Institute of Applied Ecology Chinese Academy of SciencesShenyang 110016China

The paper discusses mainly about the modelling process and related problems with examples from Chinese and French cases. Five practical problems must be solved for modelling the functioning of any landscape: ( 1) The field data are necessarily taken with a sampling procedure that implies a spatial (and often temporal) scale. (2) Every landscape modelled has to be identified, delimited and characterised before application of the hierarchical theory. (3) The functioning of a landscape involves data of multiple types (climate, soil, vegetation, fauna, buildings, communications, economy, aesthetics, etc.) which must be integrated in a holistic approach. (4) Every landscape is spatially heterogeneous, and the structure of the model must be more or less isomorphic with its heterogeneity. ( 5) The evolution of the landscape must be modelled on a rather long period of time. For all these reasons, it is necessary to build ad hoc models. Object-oriented computing languages may be useful for this purpose.

关键词： landscape modelling scale hierarchy holistic approach application