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Chemical Composition of Pellonula leonensis Fish Oils from the Congo River Obtained by Soxhlet Extraction

Open Journal of Applied Sciences 2024年第8期14卷 2112-2123页

作者： Bob Wilfrid Loumouamou Léa Béatrice Mambou Gadet michel Dzondo Multidisciplinary Food and Nutrition Research Team: Regional Center of Excellence in Food and Nutrition Faculty of Science and Technology Marien Ngouabi University Brazzaville Congo Process Engineering Laboratory UNESCO-ENSP Chair Marien Ngouabi University Brazzaville Congo Molecular and Sensory Food Engineering Laboratory National Polytechnic School (ENSP) Marien Ngouabi University Brazzaville Congo

The chemical composition of Pellonula leonensis fish oils from the Congo River (at Boko city) was carried out. The fatty acids were determined by gas chromatography. The Sn-2 position of fatty acids on glycerol was carried out by the ISO 6800 standard. The separation of the compounds (as free fatty acids, monoglycerides, diglycerides, triglycerides, sterols and methyl esters, etc.) was carried out by HPLC using gel permeation with refractometric detection. The phospholipid composition was by HPLC with an evaporative light scattering detector. We obtained oil contents of 32.10 (±0.46)%. The major fatty acids were Palmitic acid (27.41%) and oleic acid (24.23%). The SFA were of 44.50%. The MUFA represent 32.54% and PUFA 22.60%. Regarding the Sn-2 position on glycerol, 48.0% were by SFA and 51.3% were by unsaturated fatty acids. Among them 34.2% of fatty acids were 17.5% oleic acid molecules, 3.3% DHA molecules and 2.1% EPA molecules. Free fatty acids have contents of more than 62%, Diglycerides 16.63% and triglycerides 20.46%. Seven different phospholipids were identified, namely: Phosphatidylglycerol (PG), Phosphatidylethanolamine (PE), Phosphatidylinositol (PI), Phosphatidylcholine (PC), Sphingomyelin (SM), Lyso Phosphatitdylcholine (LPC) and Lyso Phosphatidylethanolamine (LPE). According to the high levels in position 2 of the glycerol of palmitic acid, the consumption of Pellonula leonensis fish could be moderate.

关键词： Pellonula leonensis Fatty Acids Sn-2 Position Triacylglycerol Phospholopids

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International Healthcare Terminologies for Morbidity New Era: SNOMED and ICD11

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Journal of Biosciences and Medicines 2024年第8期12卷 357-368页

作者： Jean Marie Rodrigues Constant Kone michel Babri Béatrice Trombert Universit Jean Monnet Saint Etienne France Felix Houphout Boigny National Polytechnic Institute Yamoussoukro Cote dIvoire

The Information Technology (IT) developments have changed the use of Healthcare terminologies from paper-based mortality statistics with the WHO international classifications of diseases (ICD) to the IT-based morbidity implementations for instance for Casemix-based healthcare funding and managing systems. This higher level of granularity is worldwide spread under the umbrella of several national modifications named ICD10 XM. These developments have met the increased use of the International Clinical Reference Terminology named SNOMED. When the updating of WHO ICD10 to WHO ICD11 was decided a merging was envisaged and a WHO SNOMED CT common work proposed a methodology to create a common formal ontology between the 11th version of the WHO International Classification of Diseases and Health Problems (ICD) and the most used in the world clinical terminology named Systematized Nomenclature of Human and Veterinary Medicine - Clinical Terms (SCT). The present work follows this unachieved work and aims to develop a SNOMED-based formal ontology for ICD11 chapter 1 using the textual definitions of ICD11 codes which is a completely new character of ICD and the ontology tools provided by SCT in the publicly available SNOMED Browser. There are two key results: the lexical alignment is complete and the ontology alignment is incomplete with the validated SNOMED concept model can be completed with not yet validated attributes and values of the SNOMED Compositional Grammar. The work opens a new era for the seamless use of both international terminologies for morbidity for instance for DRG/Casemix and clinical management use. The main limitation is that it is restricted to 1 out of 26 chapters of ICD11.

关键词： Lexical Alignment Semantic Interoperability Ontology SNOMED Concept Model ICD-11 SNOMED CT

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桥梁长寿命设计理论综述

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交通运输工程学报 2024年第3期24卷 1-24页

作者：刘永健刘江周绪红王壮孟俊苗赵鑫东 YANG Jian GHOSN michel 长安大学公路学院陕西西安710064 重庆大学土木工程学院重庆400045 AECOM 纽约纽约NY 101584 纽约城市大学土木工程学院纽约纽约NY 10031

为促进桥梁长寿命设计理论的发展,从桥梁服役寿命及其影响机理出发,总结了现有桥梁长寿命设计的研究现状和面临的主要问题,探讨了未来研究重点和方向。研究结果表明:现行各国规范根据桥梁重要性及其所在公路等级进行桥梁设计寿命的规定... 详细信息

为促进桥梁长寿命设计理论的发展,从桥梁服役寿命及其影响机理出发,总结了现有桥梁长寿命设计的研究现状和面临的主要问题,探讨了未来研究重点和方向。研究结果表明:现行各国规范根据桥梁重要性及其所在公路等级进行桥梁设计寿命的规定,多采用变寿命的设计思路,赋予不同功能、重要程度、更换难度的桥梁构、部件不同的设计寿命;桥梁的寿命取决于其在真实服役环境下的长期性能,包含环境侵蚀作用下的耐久性能、反复荷载作用下的疲劳性能和持续荷载作用下的徐变性能,受服役环境、养护干预和施工过程的影响显著;新建桥梁长寿命技术主要从设计方法和高性能材料展开研究,现有服役寿命和耐久性设计方法主要围绕环境作用、劣化机理、材料性能、施工控制和检查管理等方面,达到了“看似满足”的设计目标,尚未能实现概率水平提升和设计寿命量化,全寿命设计则还停留在理念层面,UHPC、耐候钢、FRP等高性能材料的应用是提升桥梁设计寿命的有效方式;未来应以“明确结构定位,完善性能指标体系,优化结构初始状态,改善服役微环境,控制劣化传递路径”为长寿命设计的基本框架,围绕桥梁结构的长寿基因识别与调控、桥梁微环境全寿命周期演化规律、桥梁服役寿命的全概率量化设计方法等基础理论开展研究,以建立系统的桥梁长寿命设计理论体系。

关键词：桥梁工程长寿命环境作用设计方法高性能材料

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Photometric and Spectroscopic Study of Ten Low Mass Ratio Contact Binary Systems:Orbital Stability,O'Connell Effect and Infrared Calcium Line Filling

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Research in Astronomy and Astrophysics 2024年第8期24卷 212-222页

作者： Surjit S.Wadhwa Adam Popowicz Raúl michel Petar Kostić Oliver Vince Nick F.H.Tothill Ain Y.De Horta Miroslav D.Filipović School of Science Western Sydney UniversityLocked Bag 1797PenrithNSW 2751Australia Department of Electronics Electrical Engineering and MicroelectronicsSilesian University of TechnologyAkademicka 1644120 GliwicePoland Instituto de Astronomía UNAM.A.P.87722800 EnsenadaBCMéxico Astronomical Observatory Volgina 711060 BelgradeSerbia

Low mass ratio contact binary systems are more likely to have unstable orbits and potentially *** addition,such systems exhibit characteristics such as starspots and high energy emissions(UV)suggestive of chromospheric and magnetic *** curve modeling of ten contact binary systems is *** were found to be of extreme low mass ratio ranging from 0.122 to 0.24 and three were found to be potentially unstable and possible merger *** of the infrared calcium absorption lines is a marker of increased chromospheric *** use the available Large Sky Area Multi-Object Fiber Spectroscopic Telescope spectra along with matched standard spectra(broadened for rotation)to measure the excess filling of the central core depression flux of the two main infrared calcium absorption linesλ8542 andλ*** find that all reported contact binaries have excess filling of the core flux in the infrared calcium *** of the systems reported were also observed by the Galaxy Evolution Explorer mission and we find that all three have features of excess ultraviolet emissions further adding evidence for increased chromospheric activity in low mass ratio contact *** of both orbital stability and absorption line filling is dependent on the determination of geometric and absolute parameters from light curve *** an insignificant number of contact binary light curves exhibit the O’Connell effect,usually attributed to *** discuss the inclusion of starspots in light curve solutions and how they influence the geometric and absolute parameters.

关键词： (stars)binaries eclipsing-techniques photometric-stars chromospheres

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Management of Severely Malnourished Children Aged 6 - 59 Months Hospitalized in the Pediatric Ward of Kayanza Hospital/Burundi

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Open Journal of Pediatrics 2024年第1期14卷 11-21页

作者： michel Baseka Jonathan Niyukuri Alice Ndayishimiye Sedki Az-Eddine Vestine Ntakarutimana Department of Health Nutrition Doctoral School University of Burundi Bujumbura Burundi Food Science and Technology Research Center (CRSTA) Department of Food Science and Technology (STA) Faculty of Agronomy and Bioengineering (FABI) University of Burundi Bujumbura Burundi East African Institute of Nutritional Sciences Bujumbura Burundi Faculty of Medicine University of Burundi Bujumbura Burundi Department of Biology Semlalia Faculty of Science Cadi Ayyad University Marrakech Morocco Centre de recherche en sciences naturelles et environnementales Faculty of Science University of Burundi Bujumbura Burundi

The implementation of WHO guidelines has significantly reduced hospital mortality due to severe malnutrition. Nevertheless, severe acute malnutrition in children under five remains a major public health problem in all low-income countries and is little studied. The study aimed to assess the nutritional status and quality of management of severe acute malnutrition in children aged 06 to 59 months hospitalized in the pediatric ward of Kayanza Hospital. This is a prospective study with descriptive and analytical aims over 6 months from February 10 to July 9, 2023. All children aged 6 to 59 months admitted for severe acute malnutrition are included in this study. The results show that the most affected age group is 12 to 23 months (42.55%). Marasmus is the most common clinical form, at 70.2%. Housewives and mothers from rural areas are the most affected, with rates ranging from 69.14% to 91.49%. The study shows that the reasons for consultation are respectively: edema (29.78%), diarrhea (26.59%), vomiting (19.14%), and fever (14.89%). Dehydration and hypothermia were the main complications observed in 45.74% and 22.34% respectively. Medical treatment was provided by antibiotics (44.68%), artesunate (31.91%), and resomal (21.27%). Nutritional treatment consisted of F75 100% milk and F100 100% milk. Pathologies observed were: anemia 38.29%, malaria 37.23%, urinary tract infection 12.7%, measles 11.7%. The national protocol for integrated management of acute malnutrition (PCIMA) was followed. This study shows that 72.3% of children were successfully treated, with 9.5% dropping out and dying, and 8.5% not responding. We found that malnutrition remains a public health problem, affecting mostly children aged 12 to 24 months. The main complications or pathologies associated with malnutrition are diarrhea, malaria, and fever, and the majority of children suffer from marasmus.

关键词： Severe Acute Malnutrition Child Burundi

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Fatty Acid Composition of Hazelnut Kernel Oil from Coula edulis Collected in the Republic of Congo

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Food and Nutrition Sciences 2024年第4期15卷 290-297页

作者： Josiane Enzonga Yoca Jean Paul Latran Ossoko Yves Okandza michel Didace Mvoula Tsieri Laboratoire de Contrô le et Qualit&#233 des Aliments de l&#8217Ecole Nationale Sup&#233rieure d&#8217Agronomie et de Foresterie Universit&#233 Marien NGOUABI Brazzaville Congo Université Denis Sassou NGUESSO Brazzaville Congo

Coula edulis is non-timber forest product (NTFP) used in Africa for its hazelnuts, which contain edible seeds with a demonstrated nutritional potential. However, there have been very few scientific studies of this species in the Republic of Congo. Thus, the aim of the current study was therefore to determine the fatty acid composition of the oil extracted from Coula edulis hazelnut seeds collected at random in the Republic of Congo. The oil was extracted using the Soxhlet method and its fatty acid composition was determined by gas chromatography. The extracted oil from Coula edulis hazelnut kernels is rich in monounsaturated fatty acids (95.28%), particularly oleic acid (94.5%), which classifies it as an oleic oil and gives it interesting nutritional and therapeutic properties. On the other hand, saturated fatty acids (4.15%) and polyunsaturated fatty acids (0.35%) are not well represented. Its low poly-unsaturated fatty acid content makes it more stable when stored at room temperature.

关键词： Coula edulis Fatty Acids Oil Seeds Hazelnuts Republic of Congo NTFP

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Investigation of Carbonation of Concrete Based on Crushed Sand and Admixtures

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Journal of Minerals and Materials Characterization and Engineering 2024年第5期12卷 247-264页

作者： Jacques Herve Koung à Bediang Emmanuel Elat Assoua Moukete Paul Djomou Djonga michel Mbessa Laboratory of Civil and Mechanical Engineering Department of Civil Engineering National Advanced School of Engineering of Yaounde 1 Yaounde Cameroon Laboratory of Mechanics and Materials of Civil Engineering Department of Civil Engineering CY Cergy Paris University Paris France Department of Textile and Leather Engineering National Advanced School of Engineering of Maroua Maroua Cameroon Department of Civil Engineering National Advanced School of Public Works National Advanced School of Engineering of Yaounde 1 Yaounde Cameroon

Carbonation is a natural aging process that occurs in all types of concrete. One of its primary implications is the acceleration of steel corrosion caused by the phenomena of depassivation. The goal of this research is to investigate the carbonation of quarry sand-based concrete. The concrete is made of 100% crushed sand 0/6.3, gravel 8/15, and 15/25 from the Arab Contractor quarry in Nomayos, Cameroon, with CEM II B-P 42.5 R from CIMENCAM (Cimenteries du Cameroun). The study employed two admixtures: one with a dual superplasticizing and reducing action (Sikamen) and another with a water-repellent effect (Sika liquid). Carbonation was performed on concrete samples at the following dates: 0, 7, 14, 28, 56, 90, 180 days, one year, and six months. Carbonated concrete (CC) and non-carbonated concrete (NCC) samples are compared in terms of their physical attributes and mineralogical characteristics. The results of this investigation reveal that after more than a year and six months of carbonation, porosity decreases and permeability increases. Despite the high fineness modulus of quarry sand, the compressive strength of quarry sand-based concrete is satisfactory. Carbonation depth is relatively high on some dates, exceeding the minimal cover value for concrete reinforcement. Sikament additive increases concrete compactness and durability while decreasing permeability. Sika water repellant mixes with the lime in cement to generate complimentary crystallizations that block the mortar’s capillaries, making it watertight.

关键词： Carbonation Concrete Crushed Sand Sikamant Water-Repellent

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RANKL inhibition reduces lesional cellularity and Gαs variant expression and enables osteogenic maturation in fibrous dysplasia

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Bone Research 2024年第1期12卷 165-179页

作者： Luis F.de Castro Jarred M.Whitlock Zachary michel Kristen Pan Jocelyn Taylor Vivian Szymczuk Brendan Boyce Daniel Martin Vardit Kram Rebeca Galisteo Kamran Melikov Leonid V.Chernomordik Michael T.Collins Alison M.Boyce Skeletal Disorders and Mineral Homeostasis Section National Institute of Dental and Craniofacial ResearchNational Institutes of HealthBethesdaMDUSA Section on Membrane Biology Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Institutes of HealthBethesdaMDUSA Metabolic Bone Disorders Unit National Institute of Dental and Craniofacial ResearchNational Institutes of HealthBethesdaMDUSA Department of Plastic and Reconstructive Surgery The Johns Hopkins Medical InstitutionsBaltimoreMDUSA Department of Pathology and Laboratory Medicine University of Rochester Medical CenterRochesterNYUSA NIDCR Genomics and Computational Biology Core National Institute of Dental and Craniofacial ResearchNational Institutes of HealthBethesdaMDUSA

Fibrous dysplasia(FD)is a rare,disabling skeletal disease for which there are no established *** evidence supports inhibiting the osteoclastogenic factor receptor activator of nuclear kappa-B ligand(RANKL)as a potential treatment *** this study,we investigated the mechanisms underlying RANKL inhibition in FD tissue and its likely indirect effects on osteoprogenitors by evaluating human FD tissue pre-and post-treatment in a phase 2 clinical trial of denosumab(NCT03571191)and in murine in vivo and ex vivo preclinical *** analysis of human and mouse tissue demonstrated increased osteogenic maturation,reduced cellularity,and reduced expression of the pathogenic Gαs variant in FD lesions after RANKL *** sequencing of human and mouse tissue supported these *** interaction between osteoclasts and mutant osteoprogenitors was further assessed in an ex vivo lesion model,which indicated that the proliferation of abnormal FD osteoprogenitors was dependent on *** results from this study demonstrated that,in addition to its expected antiosteoclastic effect,denosumab reduces FD lesion activity by decreasing FD cell proliferation and increasing osteogenic maturation,leading to increased bone formation within *** findings highlight the unappreciated role of cellular crosstalk between osteoclasts and preosteoblasts/osteoblasts as a driver of FD pathology and demonstrate a novel mechanism of action of denosumab in the treatment of bone disease.

关键词： dysplasia treatment finding

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Nutritional and Antioxidant Evaluation and Effect of Eggplant Consumption on Anthropometric and Hematologic Parameters in Wistar Rats

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Food and Nutrition Sciences 2024年第4期15卷 245-262页

作者： Elenga michel Nkouka Rhode Gouollaly Tsiba Wossolo Stephane Itoua Okouango Yvon Simplice Mananga Vital Multi-field Team of Research in Feeding and Nutrition (Eprancongo) Faculty of Sciences and Technology Marien Ngouabi University Brazzaville Republic of the Congo Laboratory of Human Nutrition and Feeding (LaNAH) Faculty of Sciences and Technology Marien Ngouabi University Brazzaville Republic of the Congo Department of Pharmacopeia and Traditional Medicine National Institute of Health Science & Research (IRSSA) Scientific City of Brazzaville Brazzaville Republic of the Congo Laboratory of Pharmacodynamics and Experimental Pathophysiology (L2PE) Faculty of Sciences and Technology Marien Ngouabi University Brazzaville Republic of the Congo

The aim of the present study was to evaluate the nutritional quality of green and purple eggplant, their antioxidant activity and their nutritional efficacy on Wistar rats. For nutritional quality, the parameters measured are dry matter, protein, lipid, ash, carbohydrate, iron, phosphorus, calcium, magnesium and energy content. For antioxidant activity, the parameters measured are 50% DDPH free radical inhibition concentration and total polyphenol content. Nutritional efficacy was evaluated in rats fed the control diet and in rats fed the three treated diets containing eggplant meal obtained by replacing 5%, 10%, and 15% of the control diet. The parameters measured are the amount consumed, the weight of the animal and target organs, and hematologic parameters. The results of the nutritional analysis show the following values: 13.31% protein, 2.66% lipids, 0.84% calcium, 0.12% magnesium, 0.43% phosphorus for the Solanum aethiopicum L. species and 13.47% protein, 3.66% lipids, 0.36% calcium, 0.22% magnesium, 0.35% phosphorus for the Solanum melongena L. species. In terms of antioxidant activity, we obtained DDPH inhibition percentages of 40.28 mg/ml for Solanum aethiopicum L. and 12.42 mg/ml for Solanum melongena L., respectively. Finally, hematologic and anthropometric tests showed that for the different diets used, weight loss and an increase in hematologic parameters were observed in the rats tested. This study showed that eggplant has interesting nutritional characteristics and antioxidant activity, contributing to an increase in weight and anthropometric parameters.

关键词： Fruit Vegetables Eggplant Solanum aethiopicum L. Solanum melongena L. Antioxidants Polyphenols

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自动化:撬动灵活生产的杠杆

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现代制造 2024年第2期 37-38页

作者： Stefanie michel 不详

第41届国际装配自动化展览会的展示核心是从零部件到组件和子系统直至完整的全套系统。工厂企业的设计师、决策者和采购人员都可以在这一会展中找到符合自己需求的最佳解决方案。2023年10月10~13日,著名的国际生产和装配自动化技术展Mo... 详细信息

第41届国际装配自动化展览会的展示核心是从零部件到组件和子系统直至完整的全套系统。工厂企业的设计师、决策者和采购人员都可以在这一会展中找到符合自己需求的最佳解决方案。2023年10月10~13日,著名的国际生产和装配自动化技术展Motek会展与国际粘合剂及密封技术博览会Bondexpo会展同时拉开帷幕。

关键词：装配自动化最佳解决方案采购人员密封技术会展粘合剂博览会

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