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COVID-19 patient experiences in prehospital pathways:a processual approach using life-events calendar method and state sequence analysis shows detrimental delays

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Family Medicine and Community Health 2024年第1期12卷 45-56页

作者： Romain Lutaud Sebastien Cortaredona Lea delorme Patrick Peretti-watel Juliette Mirouse Manon Borg Lucie Cattaneo Didier Thery Gaetan Gentile Christian Pradier Touitou Irit Philippe Brouqui Sophie Tardieu michel Carles Stéphanie Gentile department of General Practice Aix-Marseille UniversityMarseilleFrance AdeS MarseilleFrance Institut de Recherche pour le Développement(IRD) MarseilleFrance Assistance Publique-Hôpitaux de Marseille(AP-HM) MarseilleFrance INSERM MarseilleFrance department of Public Health Archet University HospitalNiceFrance MEPHI MarseilleFrance CEReSS-Health Service Research and Quality of life Center MarseilleFrance department of Infectious Diseases Centre Hospitalier Universitaire de NiceNiceFrance

Objectives To our best knowledge,no study in France has comprehensively investigated the prehospital history of patients admitted for severe cases of COVID-19.‘Patients’voice is an excellent means to capture data on primary care *** aimed to identify clusters of COVID-19 hospitalised patients with similar prehospital symptom sequences,and to test whether these clusters were associated with a higher risk of poor clinical *** Cross-sectional online survey using life-event *** All patients hospitalised for COVID-19 between September 2020 and May 2021 in the Infectious Disease departments in Nice and in Marseilles in *** 312 patients responded to the *** outcome measures From the day of symptom onset to the day of hospitalisation,we defined a symptom sequence as the time-ordered vector of the successive symptom grades(grade 1,grade 2,grade 3).State sequence analysis with optimal matching was used to identify clusters of patients with similar symptom *** logistic regressions were performed to test whether these clusters were associated with admission to intensive care unit(ICU)and COVID-19 sequelae after *** Three clusters of symptom sequences were identified among 312 complete prehospital pathways.A specific group of patients(29%)experienced extended symptoms of severe COVID-19,persisting for an average duration of 7.5 days before *** group had a significantly higher probability of being admitted to ICU(adjusted OR 2.01).They were less likely to know a loved one who was a healthcare worker,and more likely to have a lower level of ***,this group of patients,who were more likely to have previously visited the emergency room without exhibiting severe symptoms at that time,may have been inclined to postpone reassessment when their health *** relatives played a decisive role in their *** and relevance This study h

关键词： admitted likely life

Increasing analyzable steel thickness for thin layer activation experiments

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Nuclear Science and Techniques 2020年第3期31卷 35-44页

作者： joao Francisco de Oliveira Antunes Mauro Lucio Borges Lemos michel de Almeida Franca Julio Cezar Suita Celso Marcelo Franklin Lapa Instituto de Engenharia Nuclear Rio de Janeiro 21941-614Brazil Programa de Engenharia Nuclear-COPPE/UFRJ Riode Janeiro 21941-450Brazil

The thin layer activation technique(TLA)is very effective in wear analysis for tribological systems where disassembly is costly or *** its development in the 1970s,TLA has been applied through direct irradiation of solid targets using ionizing particle beams to obtain an activation with a specific *** profile is then used to measure wear in a variety of *** experiments rely heavily on how deep the normalized activation *** of 30μm to 50μm are obtained for constant activation by the standard method,which for many experiments is ***,many others would benefit greatly from a 300μm constant activation layer,such as high-performance engines,softer alloys(brakes),and oil transport *** this aim was the goal of this ***,we needed to find an adequate irradiation line for the TLA ***,another technique/system was developed(the Attenuation Wheel),which would bring the depth of constant activation from 50μm to 300μm.

关键词： Thin layer activation Wear Proton beam Attenuation wheel

Hygrothermal Properties of a Composite Based on Clay Soils and Diatomite

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Open journal of Civil Engineering 2024年第3期14卷 363-373页

作者： Togdjim jonas Malloum Soultan Modjinguem F. Ronelngar Mahamat S. Abdel-Khadir Alexis M. Nanimina michel Querry Mechanical Engineering department Higher National Institute of Sciences and Techniques of Abch Abch Chad Technology department University of NDjamena NDjamena Chad National Center for development Research (CNRD) NDjamena Chad Mechanical department National Institute Superior of Sciences Appliqued Lyon France

The purpose of this paper is to make a contribution to the use of diatomite as a mineral additive in the composition of compressed earth blocks. The aim is to study the influence of diatomite on the hygrothermal behaviour of composites based on clay soils. For this reason, two clay soils with different physicochemical and mineralogical compositions were incorporated with diatomite at percentages ranging from 5% to 50% with a step of 5 to produce compressed earth blocks. After assessing the hydric and thermal characteristics of the composites, it was found that the incorporation of diatomite into the clay matrix favours the absorption of water by capillary action for all the composites. The diatomite-amended blocks subjected to the rain erosion test were less eroded than the unamended blocks. In addition, BYD composites were found to be more resistant than BTD composites, due to the high percentage of clay in T soil. The thermal conductivity of the latter decreases respectively from 0.72 to 0.29 W/m∙K for BTD composites and from 0.52 to 0.21 W/m∙K for BYD composites. This reduction proves the thermal insulating properties of diatomite. despite the high capillary absorption capacity of these composites, they have good thermal properties, enabling them to be used in the construction of buildings for improved indoor thermal comfort.

关键词： Clay Soil Diatomite Capillary Absorption Erodibility and Thermal Conductivity

让-吕克·戈达尔与克里斯·马克:新浪潮运动的两条通路

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电影艺术 2024年第3期 9-14页

作者： [法]让-米歇尔·傅东王杉(译) 不详北京大学艺术学院南开大学新闻与传播学院

新浪潮运动通常被简单归结为一场发生于法国的电影语言革命,但事实上囊括了更为多元的朝向和意涵。对这场运动的界定与“人物”和“时间”两个面向息息相关,一方面关乎戈达尔和克里斯·马克两位电影人,另一方面则关乎新浪潮的缘起与延... 详细信息

新浪潮运动通常被简单归结为一场发生于法国的电影语言革命,但事实上囊括了更为多元的朝向和意涵。对这场运动的界定与“人物”和“时间”两个面向息息相关,一方面关乎戈达尔和克里斯·马克两位电影人,另一方面则关乎新浪潮的缘起与延续时间。新浪潮精神经由两位电影人的开创性探索,在接下来的几十年以多种方式与形式延续。它深远且持久地更迭电影语言、政治话语、技术与经济实践等诸多方面,其影响早已溢出作为事件或运动的“新浪潮”表象。

关键词：戈达尔克里斯·马克新浪潮运动美学实验

Late Cryogenian-Ediacaran magmatism in southern Borborema Province,NE Brazil:Ages,sources,petrogenesis,and tectonic setting

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Geoscience Frontiers 2023年第6期14卷 70-101页

作者： Fábio Santos Pereira Herbet Conceição Maria de Lourdes Silva Rosa Moacyr Moura Marinho Colombo Celso Gaeta Tassinari joão Marinho Milhomem Neto Jean-michel Lafon Programa de Pós-Graduação em Geologia e Geoquímica(PPGG) Instituto de GeociênciasUniversidade Federal do Pará(UFPA)66075-110 BelémParáBrazil Programa de Pós-Graduação em Geociências e Análise de Bacias(PGAB) Universidade Federal de Sergipe(UFS)49100-000 São CristóvãoSergipeBrazil Instituto de Geociências Universidade Federal da Bahia(UFBA)40170-290 SalvadorBahiaBrazil Instituto de Geociências Universidade de São Paulo(USP)05508-900 São PauloBrazil Laboratório de Geologia Isotópica(Pará-Iso) IG-UFPA66075-110 BelémParáBrazil

The Sergipano Orogenic System(SOS)in southern Borborema Province(NE Brazil)hosts voluminous Neoproterozoic plutonism related to the Brasiliano/Pan-African *** paper presents comprehensive whole-rock geochemical data,titanite U-Pb ages,and the first combined zircon U-Pb and Lu-Hf isotope results for plutonic rocks from the MacururéDomain to constrain their sources,petrogenesis,and tectonic *** magmatic episodes are recognized and record the evolutionary stages of the orogen.(i)Early-collisional magmatism(643–628 Ma)comprises gabbros and diorites with minor tonalites characterized by well-developed tectonic foliation and evidence of solid-state *** rocks are magnesian,high-K calc-alkaline,LILE-and LREE-enriched and provide subchondriticε_(Hf)(t)values(6.5 to4.7)and Orosirian Hf-T^(C)_(DM)model ages(1.83–1.94 Ga).Such features indicate derivation from a lithospheric mantle source metasomatized by incorporating crustal components through subduction processes prior to magma generation,possibly related to the Rhyacian Orogeny(2.20–1.96 Ga).Extensive mixing/mingling between basaltic and crust-derived magmas took place at lower crustal depths,producing coeval hybrid diorites and quartz-diorites.(ii)Syn-collisional magmatism(630–624 Ma)encompasses biotite-and muscovite-bearing granodiorites and monzogranites,preserving their structures parallel to the schistosity of the country *** rocks are leucocratic,weakly metaluminous to peraluminous,and contain abundant surmicaceous *** features and geochemical composition suggest an origin related to the partial melting of graywacke protoliths with a subordinate igneous component.(iii)Late-collisional magmatism(625–600 Ma)includes undeformed and isotropic monzonites and granodiorites,which truncate the regional *** rocks are consistently metaluminous and magnesian,showing affinities with the high-K calc-alkaline to shoshonite *** element modeling with su

关键词： Brasiliano/Pan-African Orogeny Western Gondwana Zircon and titanite U-Pb dating Hf isotope data Magma source

Hydrogeochemical Characterization of Groundwater from Fissured Aquifers in the Angovia Mine Operating Permit Area (Central-West Côte d’Ivoire)

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journal of Water Resource and Protection 2024年第1期16卷 83-101页

作者： Kouadio michel Yao Tanina Drissa Soro Tanoh Jean Jacques Koua Akaie Jean Fabrice Tchakray Yao Emile desmond Konan Brou Dibi Laboratory of Sciences and Technologies of Environment University Jean Lorougnon Guede Daloa C&ocircte d’Ivoire

The main objective of this study is to determine the hydrogeochemical specificities of the groundwater of the Angovia mine operating permit, located in the Yaouré mountains in the center-west of Côte d’Ivoire. To do so, descriptive and multivariate statistical analysis methods with the SOM (Self Organizing Maps) algorithm were applied to the physicochemical parameters of 17 boreholes using the calcite (ISC) and dolomite (ISD) saturation indices. The results obtained have shown that the groundwater in the Angovia mine operating permit area has an average temperature of 27.52°C (long rainy season) and 27.87°C (long dry season) and has an average pH of 7.09 ± 0.35 during the main rainy season and 7.32 ± 0.35 during the main dry season. They are mineralized with an average electrical conductivity of 505.98 ± 302.85 μS/cm during the long rainy season and with 450.33 ± 233.74 μS/cm as average during the long dry season. The main phenomena at the origin of groundwater mineralization are water residence time, oxidation-reduction and surface inflow. The study of the relative age of the water shows that the groundwater in the Angovia mine operating permit area is mainly undersaturated with respect to calcite and dolomite. They are therefore very old in the aquifer with a slow circulation speed during the long rainy season and the long dry season.

关键词： Hydrogeochemistry Mineralization Fissure Aquifers Operating Permits The Angovia Mine

Multivariate Approach to Characterizing Soil Quality of Gabonese’s Ferralitic Soils

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Open journal of Soil Science 2024年第4期14卷 237-268页

作者： Neil-Yohan Musadji Rolf Gaël Mabicka Obame michel Mbina Mounguengui Jean Aubin Ondo Lydie-Stella Koutika Eric Ravire Claude Geffroy Laboratoire de Chimie Des Milieux et Des Mat&#233riaux Inorganiques Laboratoire D&#8217Analyse Des Sols et Environnement D&#233partement Des Sciences Fondamentales De L&#8217Ing&#233nieur Institut National D&#8217Agronomie et De Biotechnologies Universit&#233 Des Sciences et Techniques De Masuku Franceville Gabon Institut de Chimie des Milieux et Maté riaux De Poitiers (IC2MP) Universit&#233 De Poitiers Poitiers France Laboratoire de Chimie Des Milieux et Des Mat&#233riaux Inorganiques Laboratoire D&#8217Analyse Des Sols et Environnement D&#233partement De Phytotechnologie Institut National D&#8217Agronomie et De Biotechnologies Universit&#233 Des Sciences et Techniques De Masuku Franceville Gabon Dé partement De G&#233ologie Facult&#233 Des Sciences Universit&#233 Des Sciences et Techniques De Masuku Franceville Gabon Laboratoire Pluridisciplinaire des Sciences Ecole Normale Sup&#233rieure Libreville Gabon Centre de Recherche Sur La Productivité et La Durabilit&#233 Des Plantations Industrielles Pointe Noire Republic of Congo Sucaf Gabon Somdiaa Franceville Gabon

Assessing soil quality is essential for crop management and soil temporal changes. The present study aims to evaluate soil quality in the Ferralitic soils context countrywide. This assessment was done using multivariate soil quality indice (SQI) models, such as additive quality index (AQI), weighted quality indexes (WQIadd and WQIcom) and Nemoro quality index (NQI), applied to two approaches of indicator selection: total data set (TDS) and minimum data set (MDS). Physical and chemical soil indicators were extracted from the ORSTOM’s reports resulting from a sampling campaign in different provinces of Gabon. The TDS approach shows soil quality status according to eleven soil indicators extracted from the analysis of 1,059 samples from arable soil layer (0 - 30 cm depth). The results indicated that 87% of all provinces presented a very low soil quality (Q5) whatever the model. Among soil indicators, exchangeable K+ and Mg2+, bulk density and C/N ratio were retained in MDS, using principal component analysis (PCA). In the MDS approach, 50 to 63% of provinces had low soil quality grades with AQI, WQIadd and NQI, whereas the total was observed with WQIcom. Only 25% of provinces had medium soil quality grades with AQI and NQI models, while 12.5% (NQI) and 25% (AQI) presented high quality grades. Robust statistical analyses confirmed the accuracy and validation (0.80 r P ≤ 0.016) of AQI, WQIadd and NQI into the TDS and MDS approaches. The same sensitivity index value (1.53) was obtained with AQI and WQIadd. However, WQIadd was chosen as the best SQI model, according to its high linear regression value (R2 = 0.82) between TDS and MDS. This study has important implications in decision-making on monitoring, evaluation and sustainable management of Gabonese soils in a pedoclimatic context unfavorable to plant growth.

关键词： Gabon Ferralitic Soil Soil Indicators Standard Score Function Soil Quality Indices Sustainable Soil Soil Management

Prevalence of Work-Aggravated Asthma among Bakery Workers in Abidjan (Cote d’Ivoire)

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Health 2024年第3期16卷 204-217页

作者： Loukou Leandre Konan Esme Marie Laure Essis Brou michel Kouassi Marius Kedote Julius Fobil William Yavo Ossey Bernard Yapo Issaka Tiembre National Institute of Public Health Abidjan Cote d’Ivoire Interuniversity Doctoral Program Cotonou Benin Medical Sciences Training and Research Unit Department of Public Health and Biostatistics Felix Houphouet Boigny University Abidjan C&#244te d’Ivoire Global Environmental Occupational Health (GEOHealth) Accra Ghana UFR of Pharmaceutical and Biological Sciences Department of Public Health Felix Houphou&#235t Boigny University Abidjan Cote d’Ivoire Nangui Abrogoua University Abidjan C&#244te d’Ivoire National Institute of Public Hygiene Abidjan C&#244te d’Ivoire

Introduction: Work-aggravated asthma is pre-existing or concomitant asthma whose symptoms are aggravated by the work environment. The aim of this study was to determine the prevalence of this pathology and its associated factors among bakery workers in Abidjan. Materials and Methods: This descriptive and analytical cross-sectional study was conducted over a period of four (4) months from 18 december 2019 to 18 April 2020. Two questionnaires were used, one on employees and the other on the indoor environment of bakeries. In addition, a spirometry test was performed on all bakery workers. Statistical analysis was performed using stata 15.1 software. Results: A total of 599 bakery employees, including bakers (59.73%), sales assistants/ cashiers (23.52%), cleaners (6.34%) and administrative staff (10.18%), were investigated. The mean age was 30.8 ± 8 years, with a sex ratio (M/F) = 2.2. Asthma symptoms were found in 95 (15.86%) employees, of whom 74 (77.9%) had work-related asthma and 11 (14.9%) had asthma aggravated by work. The factors associated with work-aggravated asthma were personal or family history of allergy or atopy [ORa = 3.75;CI95%: 1.56 - 8.93;p = 0.003], exposure to dust [ORa = 5.01;CI95%: 1.43 - 7.50;p = 0.011] and humidity level (60% - 70%) [ORa = 1.80;CI 95%: 0.99 - 3.28;p = 0.05]. Conclusion: Work-aggravated asthma is a reality in bakeries in Abidjan, with an estimated prevalence of 14.9%. Two of the three factors associated with this condition suggest a link with indoor air pollution. Combating air pollution in these establishments must therefore be a priority for the relevant authorities, in order to provide employees with a working environment that protects their health.

关键词： Work-Aggravated Asthma Occupational Asthma Work-Related Asthma Bakeries Abidjan Ivory Coast

The outcomes and safety of patients undergoing endoscopic retrograde cholangiopancreatography combining a single-use cholangioscope and a single-use duodenoscope:A multicenter retrospective international study

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Hepatobiliary & Pancreatic Diseases International 2024年第1期23卷 71-76页

作者： Alessandro Fugazza Matteo Colombo michel Kahaleh V.Raman Muthusamy Bick Benjamin Wim Laleman Carmelo Barbera Carlo Fabbri jose Nieto Abed Al-Lehibi Mohan Ramchandani Amy Tyberg Haroon Shahid Avik Sarkar dean Ehrlich Stuart Shermand Cecilia Binda Marco Spadaccini Andrea Iannone Kareem Khalaf Nageshwar Reddy Andrea Anderloni Alessandro Repici Division of Gastroenterology and Digestive Endoscopy Humanitas Research Hospital-IRCCSVia Manzoni 5620089RozzanoMilanoItaly Gastroenterology Rutgers Robert Wood JohnsonNew BrunswickNew JerseyUSA Vatche and Tamar Manoukian Division of Digestive Diseases University of CaliforniaLos Angeles School of Medicine at UCLALos AngelesCaliforniaUSA Division of Digestive and Liver Disorders Indiana University School of MedicineIndianapolisINUSA department of Gastroenterology and Hepatology University Hospitals LeuvenKU Leuven3000 LeuvenBelgium U.O.C.di Gastroenterologia ed Endoscopia Digestiva Ospedale Giuseppe MazziniASL TeramoItaly Gastroenterology and Digestive Endoscopy Unit Forlì-Cesena HospitalsAUSL RomagnaForlì-CesenaItaly Borland Groover Clinic JacksonvilleFloridaUSA department of Gastroenterology and Hepatology King Fahad Medical CityRiyadhSaudi Arabia Asian Institute of Gastroenterology HyderabadIndia Section of Gastroenterology Department of Emergency and Organ TransplantationUniversity of BariBari 70124Italy department of Biomedical Sciences Humanitas UniversityVia Rita Levi Montalcini 420090Pieve EmanueleMilanItaly

Background: Duodenoscope-related multidrug-resistant organism(MDRO) infections raise concerns. Disposable duodenoscopes have been recently introduced in the market and approved by regulatory agencies with the aim to reduce the risk of endoscopic retrograde cholangiopancreatography(ERCP) associated infections. The aim of this study was to evaluate the outcome of procedures performed with single-use duodenoscopes in patients with clinical indications to single-operator cholangiopancreatoscopy. Methods: This is a multicenter international, retrospective study combining all patients who underwent complex biliopancreatic interventions using the combination of a single-use duodenoscope and a single-use cholangioscope. The primary outcome was technical success defined as ERCP completion for the intended clinical indication. Secondary outcomes were procedural duration, rate of cross-over to reusable duodenoscope, operator-reported satisfaction score(1 to 10) on performance rating of the single-use duodenoscope, and adverse event(AE) rate. Results: A total of 66 patients(26, 39.4% female) were included in the study. ERCP was categorized according to ASGE ERCP grading system as 47(71.2%) grade 3 and 19(28.8%) grade 4. The technical success rate was 98.5%(65/66). Procedural duration was 64(interquartile range 15-189) min, cross-over rate to reusable duodenoscope was 1/66(1.5%). The satisfaction score of the single-use duodenoscope classified by the operators was 8.6 ± 1.3 points. Four patients(6.1%) experienced AEs not directly related to the single-use duodenoscope, namely 2 post-ERCP pancreatitis(PEP), 1 cholangitis and 1 ***: Single-use duodenoscope is effective, reliable and safe even in technically challenging procedures with a non-inferiority to reusable duodenoscope, making these devices a viable alternative to standard reusable equipment.

关键词： Single-operator cholangioscopy Single-use duodenoscope Endoscopic retrograde cholangiopancreatography Indeterminate biliary stricture Difficult biliary stones