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Creatine supplementation in exercised rats: Effects on the aerobic capacity

Open journal of Animal Sciences 2013年第1期3卷 21-26页

作者： michel barbosa de araújo Roberto C. Vieira Junior Leandro P. Moura Marcelo Costa Junior Rodrigo A. Dalia Amanda Christine da Silva Sponton Carla Ribeiro Maria Alice R. Mello Biosciences Institute Department of Physical Education Universidade Estadual Paulista Júlio de Mesquita Filho Rio Claro Brazil Biosciences Institute Department of Physical Education Universidade Estadual Paulista Júlio de Mesquita Filho Rio Claro Brazil Faculty of Nutrition Universidade Federal de Mato Grosso Cuiabá Brazil

This study aimed to analyze the possible metabolic disturbances caused by creatine supplementation on aerobic capacity of rats, inferred by the maximal lactate steady state. Forty male Wistar rats (90 days old) were distributed into two groups for eight weeks: trained group (T): rats that were submitted to a training protocol, and supplemented-trained group (TCr): rats that were submitted to a training protocol and received balanced diet supplemented with 2% creatine. The blood lactate concentrations equivalent to maximal lactate steady state during treadmill running were analyzed at the beginning and also at the end of the experiment. At the end of the experiment were done comparing the test results MLSS between the two groups. At the beginning of the experiment, prior to groups division, the majority of animals obtained MLSS at a speed of26 m/min, blood lactate concentration of 3.79 ± 0.76 mmol/L. At the end of the experiment, most of trained rats in T presented MLSS at the speed of28 m/min, blood lactate concentration of 3.37 ± 0.68 mmol/L. Most TCr had MLSS at the speed of28 m/min, blood lactate concentration of 3.52 ± 0.69 mmol/L. We conclude that creatine supplementation was not the cause of the improvement in the aerobic capacity of rats in the tread-mill exercise.

关键词： Diet Lactate Maximal Lactate Steady State Treadmill Running

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A Review of Research Activities for the Perspective of a Smart Electricity Grid in Burkina Faso

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Smart Grid and Renewable Energy 2025年第1期16卷 1-12页

作者： Brice Junior Carmel Wendenda Ilboudo Ollé michel Kam Raguilignaba Sam Laboratoire de Matriaux dHeliophysique et Environnement (LaMHE) Dpartement de Physique Universit Nazi BONI Bobo-Dioulasso Burkina Faso Laboratoire de Matriaux et Environnement (LAME) Dpartement de Physique Universit Joseph KI ZERBO Ouagadougou Burkina Faso Science du Numrique Universit Virtuelle du Burkina Faso (UV-BF) Ouagadougou Burkina Faso

This review explores the research activities surrounding the development and integration of smart electricity grids in Burkina Faso, a landlocked and arid territory in West Africa and one of the poorest countries in the world with significant energy challenges. It examines the current state of energy infrastructure in Burkina Faso, focusing on the integration of renewable energy sources, particularly solar photovoltaics. It highlights the role of smart grid technologies in enabling the efficient integration of renewable energy, improving grid stability and facilitating rural electrification. Additionally, the review addresses key challenges such as inadequate infrastructure, regulatory gaps and financial constraints that hinder the deployment of smart grids in the country. By analysing existing research and ongoing projects, this paper provides a comprehensive overview of the opportunities and barriers to implementing a smart electricity grid in Burkina Faso and offers recommendations for future development and policy frameworks.

关键词： Smart Grid Smart Building decentralised Energy Production Photovoltaic Renewable Energy

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Isolation and Preliminary Characterization of Staphylococcus aureus Lytic Phages from Wastewater Environment in Bobo-Dioulasso, Burkina Faso, West Africa

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Advances in Microbiology 2025年第1期15卷 42-57页

作者： Kobo Gnada michel Kiréopori Gomgnimbou Raymond Karlhis Yao Christiane Essoh Equipe Biologie Molculaire et Biotechnologies Laboratoire de Recherche Centre MURAZ Institut National de Sant Publique Bobo-Dioulasso Burkina Faso. Ecole Doctorale Sciences Naturelles et Agronomiques Universit Nazi BONI Bobo-Dioulasso Burkina Faso. Centre dexcellence Africain en Innovations Biotechnologiques pour lElimination des Maladies Transmission Vectorielle (CEA/ITECH-MTV) Universit Nazi BONI Bobo-Dioulasso Burkina Faso. Institut Suprieur des Sciences de la Sant (IN.S.SA) Universit Nazi BONI Bobo-Dioulasso Burkina Faso Facult des Sciences Universit Peleforo Gon COULIBALY Korhogo Rpublique de Cte dIvoire.

Staphylococcus aureus (S. aureus) is a bacterial pathogen for humans and animals. These bacteria can resist against many antibiotics and this resistance constitute an alarming worldwide human health threat due to the morbidity and mortality. Phage therapy is one of the alternative treatments. The aim of this study was to isolate and characterize lytic phages of S. aureus from different wastewater sources in Bobo-Dioulasso, Burkina Faso. Eight strains of S. aureus were isolated from different clinical samples and were used to isolate phages. The isolation and host range of phages were done by the spot test. Phages were purified by the double-layer method. Similar phages after the determination of the host range were characterized using restriction enzymes. A total of 27 phages were obtained after isolation and purification. Nine of the 27 isolates reported a broad host range (≥67%). The results of enzymatic digestion allowed to consider that all phage isolates that presented the same host range and the same genetic fingerprint are the same phage strain;whereas phages that presented the same host range and different genetic fingerprints are different phage strains. Thus, a total of 15 distinct phages isolates specific to S. aureus were characterized. This study highlighted the abundance and lytic capacity of phages isolated from wastewater from Bobo-Dioulasso’s environment against clinical strains of S. aureus. The lytic capacity of these Staphyphages could be an effective alternative tool to combat bacteria multi-resistance.

关键词： Staphylococcus aureus Lytic Phages Wastewater Isolation Burkina Faso

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Ischemic colitis with small-vessel occlusion,simultaneous total colectomy and liver transplantation:A case report

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World journal of Transplantation 2025年第2期15卷 337-343页

作者： Leonardo Yuri Kasputis Zanini Fabiana Roberto Lima michel Ribeiro Fernandes Paola Sofia Espinoza Alvarez Marcello de Souza Silva Antônio Paulo Ramos Martins Filho Tomazo Antonio Prince Franzini Lucas Souto Nacif department of Surgery Federal University of São PauloSão Paulo 04023-062Brazil department of Liver and Gastrointestinal Transplant Hospital 9 de JulhoSão Paulo 01409-002Brazil department of Pathology University of São Paulo School of MedicineSão Paulo 05403-900Brazil department of Surgical Pathology Hospital 9 de JulhoSão Paulo 01409-002Brazil department of Gastrointestinal Endoscopy Unit Hospital das Clínicas da Faculdade de Medicina da Universidade de São PauloSão Paulo 05403-010Brazil department of Endoscopy Hospital 9 de JulhoSão Paulo 01409-002Brazil

BACKGROUND The colon is the hollow viscera that proportionally has the lowest vascular supply and is more predisposed to ischemic *** the context of end-stage liver disease,various components may explain this group's greater predisposition to colonic ischemic ***,portal hypertension generates a process of coagulopathy,impairing local *** case report describes a case of ischemic colitis with small-vessel occlusion found during liver transplantation in a patient with decompensated end-stage liver *** SUMMARY A 64-year-old man with liver cirrhosis due to non-alcoholic steatohepatitis and hepatocellular *** patient underwent liver transplantation due to hepatic *** donor was a 53-year-old man who had died of a hemorrhagic *** examination revealed diffuse ischemic colitis with significant distention and *** to the condition of the colon,a subtotal colectomy was *** transplantation with warm ischemia time of 35 minutes,cold ischemia of 6 hours 30 minutes and total ischemia time of 7 hours 5 *** patient improved clinically with oral tract function and physiotherapy,but unfortunately,he developed a bloodstream infection,a new septic shock and died six months after *** Simultaneous total colectomy and orthotopic liver transplantation represent a rare *** events have a high mortality rate in the general population and are particularly important in cirrhotic patients.

关键词： Ischemic colitis Liver transplantation End-stage liver disease Acute-on-chronic liver failure Case report

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Resource Optimization in Elastic Optical Networks Using Threshold-Based Routing and Fragmentation-Aware Spectrum Allocation

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Open journal of Applied Sciences 2025年第1期15卷 168-186页

作者： Kamagaté Beman Hamidja Kanga Koffi Coulibaly Kpinan Tiekoura Konaté Adama michel Babri Ecole Suprieure Africaine des Technologies de lInformation et de la Communication (ESATIC) LASTIC Abidjan Cte dIvoire UMRI MSN INPHB INPHouphout Boigny Yamoussoukro Cte dIvoire

This paper proposes an efficient strategy for resource utilization in Elastic Optical Networks (EONs) to minimize spectrum fragmentation and reduce connection blocking probability during Routing and Spectrum Allocation (RSA). The proposed method, Dynamic Threshold-Based Routing and Spectrum Allocation with Fragmentation Awareness (DT-RSAF), integrates rerouting and spectrum defragmentation as needed. By leveraging Yen’s shortest path algorithm, DT-RSAF enhances resource utilization while ensuring improved service continuity. A dynamic threshold mechanism enables the algorithm to adapt to varying network conditions, while its fragmentation awareness effectively mitigates spectrum fragmentation. Simulation results on NSFNET and COST 239 topologies demonstrate that DT-RSAF significantly outperforms methods such as K-Shortest Path Routing and Spectrum Allocation (KSP-RSA), Load Balanced and Fragmentation-Aware (LBFA), and the Invasive Weed Optimization-based RSA (IWO-RSA). Under heavy traffic, DT-RSAF reduces the blocking probability by up to 15% and achieves lower Bandwidth Fragmentation Ratios (BFR), ranging from 74% to 75%, compared to 77% - 80% for KSP-RSA, 75% - 77% for LBFA, and approximately 76% for IWO-RSA. DT-RSAF also demonstrated reasonable computation times compared to KSP-RSA, LBFA, and IWO-RSA. On a small-sized network, its computation time was 8710 times faster than that of Integer Linear Programming (ILP) on the same network topology. Additionally, it achieved a similar execution time to LBFA and outperformed IWO-RSA in terms of efficiency. These results highlight DT-RSAF’s capability to maintain large contiguous frequency blocks, making it highly effective for accommodating high-bandwidth requests in EONs while maintaining reasonable execution times.

关键词： Elastic Optical Networks (EONs) Spectrum Fragmentation Routing and Spectrum Allocation (RSA) Connection Rerouting Heuristic

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Considerations for the Conduction and Interpretation of FAIRness Evaluations

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Data Intelligence 2020年第1期2卷 285-292页

作者： Ricardo de Miranda Azevedo michel Dumontier Institute of Data Science Maastricht UniversityUniversiteitssingel 60Maastricht 6229 ERThe Netherlands

The FAIR principles were received with broad acceptance in several scientific ***,there is still some degree of uncertainty on how they should be *** self-report questionnaires have been proposed to assess the implementation of the FAIR ***,the FAIRmetrics group released 14,general-purpose maturity for representing ***,these metrics were conducted as open-answer ***,these metrics have been implemented into a software that can automatically harvest metadata from metadata providers and generate a principle-specific FAIRness *** so many different approaches for FAIRness evaluations,we believe that further clarification on their limitations and advantages,as well as on their interpretation and interplay should be considered.

关键词： FAIR metrics FAIR principles FAIR data FAIRness Implementation Maturity indicators Scientific community

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Ferric carboxymaltose for anemia in Crohn’s disease patients at a tertiary center:A retrospective observational cohort study

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World journal of Clinical Cases 2023年第12期11卷 2740-2752页

作者： Natália Souza Nunes Siqueira Livia Bitencourt Pascoal Bruno Lima Rodrigues Marina Moreira de Castro Alan Sidnei Corrêa Martins Dante Orsetti Silva araújo Luis Eduardo Miani Gomes michel Gardere Camargo Maria de Lourdes Setsuko Ayrizono Raquel Franco Leal Inflammatory Bowel Disease Research Laboratory GastrocenterColorectal Surgery UnitSchool of Medical SciencesUniversity of Campinas(Unicamp)Campinas 13083-878São PauloBrazil

BACKGROUND Although the gastrointestinal tract is the most affected by Crohn’s disease(CD),the condition triggers other consequent manifestations,and iron deficiency anemia(IDA)is one of the most ***(IV)iron replacement is currently available through several drugs,such as ferric hydroxide sucrose and ferric carboxymaltose(FCM).However,the clinical management of these conditions can be *** To elucidate the drug’s effectiveness,the present study analyzed,through medical records,the clinical and epidemiological data of a cohort of patients with active CD who received IV FCM for the IDA *** This retrospective observational study included 25 patients with active CD,severe anemia,and refractory to previous conventional *** were evaluated two times:During the last treatment with ferric hydroxide sucrose and treatment with *** After treatment with FCM,parameters of IDA assessment significantly improved,serum hemoglobin(Hb)levels increased in 93%of patients(Pdeveloped CD later in life after the age of 40(A3)and with a stenosing(B2)and fistulizing(B3)*** values of Hb and hematocrit after ferric hydroxide sucrose treatment remained similar to those found before *** This study demonstrated that FCM is an important therapeutic strategy for treating IDA in CD patients,achieving satisfactory results in refractory cases.

关键词： Ferric carboxymaltose Iron deficiency anemia Crohn’s disease Inflammatory bowel disease Anemia Clinical management

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Proportional fuzzy feed-forward architecture control validation by wind tunnel tests of a morphing wing

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Chinese journal of Aeronautics 2017年第2期30卷 561-576页

作者： michel joёl Tchatchueng Kammegne Ruxandra Mihaela Botez Lucian Teodor Grigorie Mahmoud Mamou Youssef Mebarki Ecole de Technologie Superieure Montreal H3C1K3 Canada University of Craiova Craiova Dolj 200585 Romania Aerodynamics Laboratory NRC Aerospace National Research Council Canada Ottawa K1AOR6 Canada

In aircraft wing design,engineers aim to provide the best possible aerodynamic performance under cruise flight conditions in terms of lift-to-drag *** control surfaces such as flaps,ailerons,variable wing sweep and spoilers are used to trim the aircraft for other flight *** appearance of the morphing wing concept launched a new challenge in the area of overall wing and aircraft performance improvement during different flight segments by locally altering the flow over the aircraft＇s *** paper describes the development and application of a control system for an actuation mechanism integrated in a new morphing wing *** controlled actuation system includes four similar miniature electromechanical actuators disposed in two parallel actuation *** experimental model of the morphing wing is based on a full-scale portion of an aircraft wing,which is equipped with an *** upper surface of the wing is a flexible one,being closed to the wing tip;the flexible skin is made of light composite *** four actuators are controlled in unison to change the flexible upper surface to improve the flow quality on the upper surface by delaying or advancing the transition point from laminar to turbulent *** actuators transform the torque into vertical *** bases are fixed on the wing ribs and their top link arms are attached to supporting plates fixed onto the flexible skin with *** actuators push or pull the flexible skin using the necessary torque until the desired vertical displacement of each actuator is *** four vertical displacements of the actuators,correlated with the new shape of the wing,are provided by a database obtained through a preliminary aerodynamic optimization for specific flight *** control system is designed to control the positions of the actuators in real time in order to obtain and to maintain the desired shape of the wing for a specified flight *** feas

关键词： Actuators Control Experimental validation Morphing wing Wind tunnel test

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Increasing analyzable steel thickness for thin layer activation experiments

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Nuclear Science and Techniques 2020年第3期31卷 35-44页

作者： joao Francisco de Oliveira Antunes Mauro Lucio Borges Lemos michel de Almeida Franca Julio Cezar Suita Celso Marcelo Franklin Lapa Instituto de Engenharia Nuclear Rio de Janeiro 21941-614Brazil Programa de Engenharia Nuclear-COPPE/UFRJ Riode Janeiro 21941-450Brazil

The thin layer activation technique(TLA)is very effective in wear analysis for tribological systems where disassembly is costly or *** its development in the 1970s,TLA has been applied through direct irradiation of solid targets using ionizing particle beams to obtain an activation with a specific *** profile is then used to measure wear in a variety of *** experiments rely heavily on how deep the normalized activation *** of 30μm to 50μm are obtained for constant activation by the standard method,which for many experiments is ***,many others would benefit greatly from a 300μm constant activation layer,such as high-performance engines,softer alloys(brakes),and oil transport *** this aim was the goal of this ***,we needed to find an adequate irradiation line for the TLA ***,another technique/system was developed(the Attenuation Wheel),which would bring the depth of constant activation from 50μm to 300μm.

关键词： Thin layer activation Wear Proton beam Attenuation wheel

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Late Cryogenian-Ediacaran magmatism in southern Borborema Province,NE Brazil:Ages,sources,petrogenesis,and tectonic setting

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Geoscience Frontiers 2023年第6期14卷 70-101页

作者： Fábio Santos Pereira Herbet Conceição Maria de Lourdes Silva Rosa Moacyr Moura Marinho Colombo Celso Gaeta Tassinari joão Marinho Milhomem Neto Jean-michel Lafon Programa de Pós-Graduação em Geologia e Geoquímica(PPGG) Instituto de GeociênciasUniversidade Federal do Pará(UFPA)66075-110 BelémParáBrazil Programa de Pós-Graduação em Geociências e Análise de Bacias(PGAB) Universidade Federal de Sergipe(UFS)49100-000 São CristóvãoSergipeBrazil Instituto de Geociências Universidade Federal da Bahia(UFBA)40170-290 SalvadorBahiaBrazil Instituto de Geociências Universidade de São Paulo(USP)05508-900 São PauloBrazil Laboratório de Geologia Isotópica(Pará-Iso) IG-UFPA66075-110 BelémParáBrazil

The Sergipano Orogenic System(SOS)in southern Borborema Province(NE Brazil)hosts voluminous Neoproterozoic plutonism related to the Brasiliano/Pan-African *** paper presents comprehensive whole-rock geochemical data,titanite U-Pb ages,and the first combined zircon U-Pb and Lu-Hf isotope results for plutonic rocks from the MacururéDomain to constrain their sources,petrogenesis,and tectonic *** magmatic episodes are recognized and record the evolutionary stages of the orogen.(i)Early-collisional magmatism(643–628 Ma)comprises gabbros and diorites with minor tonalites characterized by well-developed tectonic foliation and evidence of solid-state *** rocks are magnesian,high-K calc-alkaline,LILE-and LREE-enriched and provide subchondriticε_(Hf)(t)values(6.5 to4.7)and Orosirian Hf-T^(C)_(DM)model ages(1.83–1.94 Ga).Such features indicate derivation from a lithospheric mantle source metasomatized by incorporating crustal components through subduction processes prior to magma generation,possibly related to the Rhyacian Orogeny(2.20–1.96 Ga).Extensive mixing/mingling between basaltic and crust-derived magmas took place at lower crustal depths,producing coeval hybrid diorites and quartz-diorites.(ii)Syn-collisional magmatism(630–624 Ma)encompasses biotite-and muscovite-bearing granodiorites and monzogranites,preserving their structures parallel to the schistosity of the country *** rocks are leucocratic,weakly metaluminous to peraluminous,and contain abundant surmicaceous *** features and geochemical composition suggest an origin related to the partial melting of graywacke protoliths with a subordinate igneous component.(iii)Late-collisional magmatism(625–600 Ma)includes undeformed and isotropic monzonites and granodiorites,which truncate the regional *** rocks are consistently metaluminous and magnesian,showing affinities with the high-K calc-alkaline to shoshonite *** element modeling with su

关键词： Brasiliano/Pan-African Orogeny Western Gondwana Zircon and titanite U-Pb dating Hf isotope data Magma source

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