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Rates and risk factors for suicidal ideation,suicide attempts and suicide deaths in persons with HIV:a systematic review and meta-analysis

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General Psychiatry 2021年第2期34卷 60-68页

作者： matt Pelton matt Ciarletta Holly Wisnousky Nicholas Lazzara monica manglani Djibril m ba Vernon m Chinchillli Ping Du Anna E Ssentongo Paddy Ssentongo Department of Public Health Sciences The Pennsylvania State University College of MedicineHersheyPennsylvaniaUSA Department of Surgery The Pennsylvania State University College of MedicineHersheyPennsylvaniaUSA Center for Neural Engineering Department of Engineering Science and MechanicsThe Pennsylvania State UniversityUniversity ParkPennsylvaniaUSA

background People living with HIV/AIDS(PLWHA)must contend with a significant burden of ***,current studies of this demographic have yielded wide variations in the incidence of suicidality(defined as suicidal ideation,suicide attempt and suicide deaths).Aims This systematic review and meta-analysis aimed to assess the lifetime incidence and prevalence of suicidality in *** Publications were identified from Pubmed(mEDLINE),SCOPUS,OVID(mEDLINE),Joanna Briggs Institute EBP and Cochrane Library databases(from inception to before 1 February 2020).The search strategy included a combination of medical Subject Headings associated with suicide and *** independently screened records,extracted outcome measures and assessed study *** were pooled using a random-effects *** and meta-regression analyses were conducted to explore the associated risk factors and to identify the sources of *** outcomes were lifetime incidence of suicide completion and lifetime incidence and prevalence of suicidal ideation and suicide *** A total of 185199 PLWHA were identified from 40 studies(12 cohorts,27 cross-sectional and 1 nested case-control).The overall incidence of suicide completion in PLWHA was 10.2/1000 persons(95%CI:4.5 to 23.1),translating to 100-fold higher suicide deaths than the global general population rate of 0.11/1000 *** lifetime prevalence of suicide attempts was 158.3/1000 persons(95%CI:106.9 to 228.2)and of suicidal ideation was 228.3/1000 persons(95%CI:150.8 to 330.1).meta-regression revealed that for every 10-percentage point increase in the proportion of people living with HIV with advanced disease(AIDS),the risk of suicide completion increased by 34 per 1000 *** quality of evidence by Grading of Recommendations,Assessment,Development and Evaluations for the suicide deaths was graded as‘moderate’*** The risk of suicide death is 100-fold higher in people living wit

关键词： lifetime suicide analysis

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African Swine Fever Virus mGF360-12L Inhibits Type Ⅰ Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway

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Virologica Sinica 2021年第2期36卷 176-186页

作者： Yisha Zhuo Zeheng Guo Tongtong ba Cheng Zhang Lihua He Cuiping Zeng Hanchuan Dai College of Veterinary medicine Huazhong Agricultural UniversityWuhan 430070China

African swine fever(ASF)is an infectious transboundary disease of domestic pigs and wild boar and spreading throughout *** is no vaccine and treatment *** immune escape strategies of African swine fever virus(ASFV)are crucial factors affecting immune prevention and vaccine ***360 genes have been implicated in the modulation of the IFN-Ⅰ*** molecular mechanisms contributing to innate immunity are poorly *** this study,we demonstrated that ASFV mGF360-12 L(mGF360 families 12 L protein)significantly inhibited the mRNA transcription and promoter activity of IFN-βand NF-κB,accompanied by decreases of IRF3,STING,TBK1,ISG54,ISG56 and AP-1 m RNA ***,mGF360-12 L might suppress the nuclear localization of p50 and p65 mediated by classical nuclear localization signal(NLS).Additionally,mGF360-12 L could interact with KPNA2,KPNA3,and KPNA4,which interrupted the interaction between p65 and KPNA2,KPNA3,*** further found that mGF360-12 L could interfere with the NF-κB nuclear translocation by competitively inhibiting the interaction between NF-κB and nuclear transport *** findings suggested that mGF360-12 L could inhibit the IFN-Ⅰproduction by blocking the interaction of importinαand NF-κB signaling pathway,which might reveal a novel strategy for ASFV to escape the host innate immune response.

关键词： African swine fever virus(ASFV) mGF360-12L IFN-Ⅰ NF-κB Nuclear transport

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基于射流机理的泥浆罐清洗工艺参数研究

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流体机械 2024年第1期52卷 62-68页

作者：韦志超李欣曲玉栋庞雷巴胜富童岭王永强鲁飞合肥通用机械研究院有限公司合肥230031 合肥通用机械研究院有限公司通用机械复合材料技术安徽省重点实验室合肥230031 铜陵有色金属集团股份有限公司安徽铜陵244000

针对传统钻井泥浆罐清洗采用人工进罐作业,存在安全隐患及效率低等问题,结合泥浆罐结构和罐内油泥沉积特点,从泥浆罐清洗工艺出发,分析“以油洗油”射流方式对罐内油泥冲击、破碎和溶解的清洗机理,开展射流轨迹模型、喷枪清洗模式、射... 详细信息

针对传统钻井泥浆罐清洗采用人工进罐作业,存在安全隐患及效率低等问题,结合泥浆罐结构和罐内油泥沉积特点,从泥浆罐清洗工艺出发,分析“以油洗油”射流方式对罐内油泥冲击、破碎和溶解的清洗机理,开展射流轨迹模型、喷枪清洗模式、射流打击力等研究。结果表明,当射流压力为0.7 mPa、流量为500 L/min、喷嘴出口直径为18 mm时,以白油为射流清洗介质,当靶距为8 m时,射流打击力为213 N,所研制的三维旋转喷枪完全满足典型钻井泥浆罐清洗作业要求。同时,三维旋转喷枪设置有罐底和罐壁2种分区清洗模式,通过清洗模式的切换,实现泥浆罐全方位清洗。研究结果可为泥浆站钻井泥浆罐安全、高效、自动化清洗提供参考。

关键词：钻井泥浆罐射流清洗射流轨迹射流打击力靶距

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Recent advances and opportunities in mXene-based liquid crystals

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Infomat 2024年第3期6卷 1-21页

作者： Ken Aldren S.Usman Jizhen Zhang Kevinilo P.marquez mia Angela N.Judicpa Peter A.Lynch Annabelle Bedford babak Anasori Joselito m.Razal Institute for Frontier materials Deakin UniversityGeelongVictoriaAustralia manufacturing Commonwealth Scientific and Industrial Research Organization(CSIRO)Waurn PondsVictoriaAustralia Institute of Chemistry University of the Philippines-Los BañosLagunaPhilippines School of materials Engineering Purdue UniversityWest LafayetteIndianaUSA Department of mechanical and Energy Engineering Indiana University-Purdue UniversityIndianapolisIndianaUSA

The recent progress on the liquid crystalline(LC)dispersion of two-dimensional(2D)transition metal carbides(mXenes)has propelled this unique nanomaterial into a realm of high-performance architectures,such as films and ***ally,compared to architectures made from typical non-LC dispersions,those derived from LC mXene possess tunable ion transport routes and enhanced conductivity and physical properties,demonstrating great potential for a wide range of applications,such as electronic displays,smart glasses,and thermal camouflage *** review provides an overview of the progress achieved in the production and processing of LC mXenes,including critical discussions on satisfying the required conditions for LC *** also highlights how acquiring LC mXenes has broadened the current solution-based manufacturing paradigm of mXene-based architectures,resulting in unprecedented performances in their conventional applications(e.g.,energy storage and strain sensing)and in their emerging uses(e.g.,tribology).Opportunities for innovation and foreseen challenges are also discussed,offering future research directions on how to further benefit from the exciting potential of LC mXenes with the aim of promoting their widespread use in designing and manufacturing advanced materials and applications.

关键词： liquid crystals multi-functional materials mXenes solution-based processing

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复合植物多糖对肉兔生长性能、养分表观消化率和血清指标的影响

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饲料研究 2024年第5期47卷 48-52页

作者：张风荣于枫王赠超王辰姜八一徐海滨山东畜牧兽医职业学院山东潍坊261061

试验旨在研究复合植物多糖对肉兔生长性能、养分表观消化率和血清指标的影响。将120只肉兔随机分为4组,每组15个重复,每个重复2只肉兔。对照组饲喂基础饲粮,复合植物多糖Ⅰ组、复合植物多糖Ⅱ组、复合植物多糖Ⅲ组分别在基础饲粮中添加0... 详细信息

试验旨在研究复合植物多糖对肉兔生长性能、养分表观消化率和血清指标的影响。将120只肉兔随机分为4组,每组15个重复,每个重复2只肉兔。对照组饲喂基础饲粮,复合植物多糖Ⅰ组、复合植物多糖Ⅱ组、复合植物多糖Ⅲ组分别在基础饲粮中添加0.01%、0.05%、0.10%复合植物多糖。试验期35 d。结果显示,3个复合植物多糖添加组的末重、平均日增重均显著高于对照组(Pm (Igm)、白细胞介素-6 (IL-6)的含量和超氧化物歧化酶(SOD)活性均显著高于对照组(PmDA)含量与谷草转氨酶(AST)、谷丙转氨酶(ALT)活性显著低于对照组(P<0.05)。研究表明,饲粮中添加复合植物多糖能够改善肉兔的生长性能、养分表观消化率和血清指标。在肉兔养殖中,选择0.05%复合植物多糖效果较好。

关键词：复合植物多糖肉兔生长性能养分表观消化率免疫指标抗氧化指标

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mRNA expression of CYP4 in marine polychaete marphysa sanguinea in response to benzo[a]pyrene

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Acta Oceanologica Sinica 2019年第6期38卷 46-53页

作者： Wanjuan Li Huan Zhao Fuyang ba Shaojuan Li Xiupeng Sun Dazuo Yang Yibing Zhou Key Laboratory of marine Bioresource Restoration and Habitat Reparation in Liaoning Province Dalian Ocean UniversityDalian 116023China marine and Fisheries Technology Center of Pan Shan Country Panjin 124000China

Rapid amplification of cDNA ends (RACE) and real-time polymerase chain reaction (RT-PCR) were carried out to analyze the CYP4 gene expression in polychaete marphysa sanguinea exposed to benzo[a]pyrene (baP) in this study. The full length of msCYP4 cDNA was 2 470 bp, and it encoded 512 amino acids. The deduced amino acid sequence showed 47% identity with CYP4F from frog Xenopus tropicalis and shared high homology with other known CYP4 sequences. To analyse the role of CYP4 in protecting m. sanguinea from baP exposure, three baP groups were established: 0.5, 5 and 50 μg/L. Polychaetes were sampled after 3, 7 and 12 d. At 0.5 μg/L, the effect of baP on msCYP4 gene expression increased with time prolonged. msCYP4 gene expression curve showed Ushaped trend with time in 5 and 50 μg/L baP groups. Therefore, msCYP4 gene may play an important role in maintaining the balance of cellular metabolism and protecting m. sanguinea from baP toxicity.

关键词： marphysa sanguinea CYP4 benzo[a]pyrene toxicity effect

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Direct growth of Fe3O4-moO2 hybrid nanofilm anode with enhanced electrochemical performance in neutral aqueous electrolyte

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Progress in Natural Science:materials International 2016年第3期26卷 258-263页

作者： Ruizhi Li Xin ba Yimeng Wang Wenhua Zuo Chong Wang Yuanyuan Li Jinping Liu School of Chemistry Chemical Engineering and Life Science and State Key Laboratory of Advanced Technology for Materials Synthesis and ProcessingWuhan University of Technology Institute of Nanoscience and Nanotechnology Department of Physics Central China Normal University School of Optical and Electronic Information Huazhong University of Science and Technology

To enhance the electrochemical energy storage performance of supercapacitors(SCs), the current researches are general directed towards the cathode materials. However, the anode materials are relatively less studied. In the present work, FeO-moO(FO-mO) hybrid nano thin film directly grown on Ti substrate is investigated, which is used as high-performance anode material for SCs in LiSOelectrolyte with the comparison to pristine FeOnanorod array. The areal capacitance of FO-mO hybrid electrode was initially found to be 65.0 m F cmat 2 m Vsand continuously increased to 260.0% after 50 cycles of activation. The capacitance values were considerably comparable or higher than many reported thinfilm iron oxide-based anodes in neutral electrolyte. With the protection of moOshell, the FO-mO electrode developed in this study also exhibited excellent cyclic stability(increased to 230.8% after 1000cycles). This work presents a promising way to improve the electrochemical performance of iron oxidebased anodes for SCs.

关键词： magnetite moO2 Supercapacitor Binder-free anode Hybridization

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心脏磁共振评估肾素-血管紧张素-醛固酮系统的心血管相互作用：动脉粥样硬化的多种族研究

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中华高血压杂志(中英文) 2024年第6期32卷 600-600页

作者： Varadarajan V marques mD Venkatesh ba Allison m Ostovaneh mR Yoneyama K Donekal S Shah RV murthy VL Wu CO Tracy RP Ouyang P Rochitte EC Bluemke DA Lima JAC 袁源练桂丽

小型研究已描述了肾素-血管紧张素-醛固酮系统在心血管系统中的作用。该研究旨在探讨醛固酮和血浆肾素活性（plasma renin activity,PRA）与心血管结构和功能的关系。方法：研究者评估在2003-2005年进行醛固酮和PRA检测，并在2010年接...

小型研究已描述了肾素-血管紧张素-醛固酮系统在心血管系统中的作用。该研究旨在探讨醛固酮和血浆肾素活性（plasma renin activity,PRA）与心血管结构和功能的关系。方法：研究者评估在2003-2005年进行醛固酮和PRA检测，并在2010年接受心脏磁共振检查的动脉粥样硬化多种族研究参与者的随机样本。排除服用血管紧张素转换酶抑制药或血管紧张素受体阻滞药的参与者。结果：醛固酮组615例，平均年龄（61.6±8.9）岁；肾素组580例，平均年龄（61.5±8.8）岁，两组女性占比均约50%。

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Effect of γ phase on mechanical behavior and detwinning evolution of directionally solidified Ni-mn-Ga alloys under uniaxial compression

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Journal of materials Science & Technology 2021年第7期66卷 91-96页

作者： Ying Niu Yue Wang Long Hou Lansong ba Yanchao Dai Yves Fautrelle Zongbin Li Zhongming Rena Xi Li State Key Laboratory of Advanced Special Steels Shanghai UniversityShanghai200072China EPm-madylam ENSHMG BP 38402St Martin d'Heres CedexFrance Key Laboratory for Anisotropy and Texture of materials Northeastern UniversityShenyang110819China

Specimens with single-phase martensite, net-like γ/martensite mixed structure and lamella-likeγ/martensite mixed structure were designed to investigate the effect of the γ phase on the mechanical behavior and the detwinning of non-modulated(Nm) martensitic variant in Ni-rich Ni-mn-Ga alloys under uniaxial compression. It can be found the existence of the γ phase significantly enhances the compressive stresses, and the net-like γ phase specimen presents a higher value of compressive strain than that of the lamella-like γ phase specimen. Especially, the detwinning plateau of the lamella-like γ phase specimen is almost invisible due to the martensite colonies with low Schmid factors. Finally, according to the calculation of deformation gradient tensor, we found that the tensors along compression direction(εzz) of net-like γ phase/martensite mixed structure specimen and single-phase martensite specimen are lower than that of the specimen with lamella-like γ phase/martensite mixed structure, which well explained the detwinning strain for these specimens. The present study not only highlights the role ofγ phase on the mechanical behavior, but also provides more guidelines for the mechanical training of Ni-mn-Ga shape memory alloys.

关键词： Ni-mn-Ga alloys Directional solidification Compression Detwinning

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云南德钦县一中河泥石流成灾特征及危险性评价

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中国地质灾害与防治学报 2024年第5期35卷 103-109页

作者：宋银陈亮王研何清杨林巴净慧陈典云南地质工程第二勘察院有限公司云南昆明650218 中国地质科学院北京100081 中国地质环境监测院北京100081

云南省德钦县是我国遭受泥石流灾害最严重的地区之一。德钦县一中河曾多次暴发大规模的泥石流灾害,对沟口处居民区及G214国道造成严重破坏和巨大经济损失。为探明一中河上游源区潜在物源在暴雨+地震工况下形成泥石流灾害的危险区范围和... 详细信息

云南省德钦县是我国遭受泥石流灾害最严重的地区之一。德钦县一中河曾多次暴发大规模的泥石流灾害,对沟口处居民区及G214国道造成严重破坏和巨大经济损失。为探明一中河上游源区潜在物源在暴雨+地震工况下形成泥石流灾害的危险区范围和启动机制,在现场调查和成因分析的基础上,以无人机贴近摄影成果高精度的DEm为地形数据,运用RAmmS软件对暴雨+地震工况下体积为16.05×10^(4) m^(3)的泥石流进行模拟,划定了一中河流域内两处危险区,并阐述了一中河泥石流灾害成灾模式。研究结果表明:一中河泥石流属于高原山区沟谷型黏性泥石流,具有规模大、高易发、危害大的特点,其成灾机制概括为高位崩滑体-碎屑流-泥石流-堰塞湖-溃决洪水的沟谷灾害链;危险区Ⅰ位于G214国道至德维路区域,危险区Ⅱ为沟口区域,此区域易发生堆积和堵塞,危险性极高;泥石流运动过程中最大流速达23.93 m/s,最大冲击力为1000 kPa,最大堆积深度为9.33 m,泥石流一次最大冲出体积约8×10^(4) m^(3),危险区范围约0.31 km^(2)。结果可为一中河泥石流治理工程提供科学依据,对德钦县地质灾害综合防治能力提升具有重要实际意义。

关键词：德钦县泥石流 G214国道成灾机制危险区数值模拟

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