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ALTeRATION IN eNTeROCYTe GeNe eXPReSSION MAY eXPLAIN STRUCTURAL AND FUNCTIONAL CHANGeS FOLLOWING GLUTAMINe SUPPLeMeNTeD PAReNTeRAL NUTRITION

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Chinese Medical Sciences Journal 1999年第2期 49-53页

作者： $$$$ Jiang Zhuming, MD Liu Yuewu, MD, phd , Ma Yongxian, MD , Bai Manxi,MD, phd , Qiang Boqing, phd  ,Robert Smith, MD Wlley Souba, MD , ScD and Douglas Wilmore, MD Department of Surgery, Peking Department of Surgery Peking Union Medical College Hospital Beijing 100730 Molecular Biology Laboratory of Chinese Academy of Medical Sciences Beijing 100730 Joslin Diabetic Center Department of Surgery Massachusetts General Hospital and Brigham and Women's Hospital Harvard Medical School

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An intensive study of the Auto Industry Development Policy

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中国汽车（英文版） 2004年第8期 12-19页

作者： ZHANG Ming phd ( SAIC )

In reading up the Auto Industry Development Policy (AIDP) NDRC promulgated, some changes are found compared to its 1994-version, in terms of content, structure, way of promulgation and department responsible for the interpretation of it. It clarifies many policy advice and policy orientation in developing the auto industry. Therefore, the AIDP is of significance in maintaining the healthy development of the auto industry and the macro control of the State economy.

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Acupuncture on Intracellular Ionic Distribution inMuscle Injury and Its Mechanism

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北京体育大学学报 1995年第S2期18卷 35-42页

作者： QU Zhuqing LU Dinghou WANG Yirun (36 years old, phd. lecturer)

While delayed structural alterations of muscles(DSAM) induced by strenuous exercises have always been one of the commoest findings in sports-related muscle injuries, its pathogenesis remains unidentified. And although acupuncture at Ashi points has proved its efficacy in halting the progress of DASM and speeding up its recovery, we know very little about the underlying mechanism. This paper presents our work on these problems by using amphibian DSAM models created by electrostimulation, and such research tools as electromicroscopy, enzymology, the fluores cence indicator, Fura 2, and electron probe microanalysis (ePMA). Our results indicate:1) As revealed by ePMA, cytoplasmic Ca continued to rbe,reaching 3.07 and 5. 33 mmol/kg dry wt. 3 and 6hrs afterelectrostimlation respectively. Analysis of regions with variousstructural alterations showed rise of Ca concentration inparallel with severity of myofibrillar injury. Testing with Fura 2also demonstrated obvious increase of free Ca++ in cytoplasm 3 hrs after electrostimulation. All these showed a positive correlation between DSAM and the increase of intracellular Ca++.2) Further study to explore the possible mechanisms underlying the increase of cytoplasmic Ca++ revealed two sources. During the initial rise of cytoplasmic Ca, a decline of sarcoplasmic reticulum Ca content was found, suggesting the contribution of sarcoplasmic reticulum Ca. However, no further decline was noted despite continued rise of cytoplasmic Ca, which, then, could only be accounted for by extracellular contribution.3) In skeletal muscles after long-term exhaustive stimulation and in those with delayed structural alterations,the inereased cytoplasmic Ca was quickly lowered by acupuncture, down to lpretest level 10 minutes after acupuncture. Meanwhile,no marked change in sarcoplasmic reticulum Ca content and in enzymic activity of Ca, Mg-ATPase was found, indicating no contribution on their part to the quick lowering of cytoplasmic Ca. But a rapid

关键词： Acupuncture Delayed Structural Alterations of Muscle (DSAM) electron Probe Microanalysis (ePMA) Fura 2 Ca++, Calcium Pump Na-Ca exchange Sarcoplasmic Reticulum (SR)

Learning ACT: An Acceptance and Commitment Therapy Skills-Training Manual for Therapists Pap/DVD

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Pathway Analysis for Drug Discovery: Computational Infrastructure and Applications 1

2007年

作者： Jason Luoma phd Steven C. Hayes phd Robyn D. Walser phd

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Inherited Wolff–Parkinson–White Syndrome

丛书名： Wiley Series on Technologies for the Pharmaceutical Industry

2008年

作者： Anton Yuryev phd

ISBN: (数字)9780470399279

ISBN: (纸本)9780470107058

This book introduces drug researchers to the novel computational approaches of pathway analysis and explains the existing applications that can save time and money in the drug discovery process. It covers traditional computational methods and software for pathway analysis microarray, proteomics, and metabolomics. It explains pathway reconstruction of diseases and toxic states, pathway analysis in various phases, dynamic modeling of drug responses, and more. This is a core resource for drug discovery and pharmaceutical industry researchers, chemists, and biologists and for professionals in related fields.

关键词： Drug development Data processing. DNA microarrays Data processing. Computational biology. Drug Design. Computational Biology. Microarray Analysis methods.

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Cardiovascular Innovations and Applications 2016年第B2期1卷 187-197页

作者： Yang Liu,MD,phd Yumei Xue,MD,phd Shulin Wu,MD,FACC,FHRS Dan Hu,MD,phd,FHRS Guangdong Cardiovascular Institute Guangdong General HospitalGuangdong Academy of Medical SciencesGuangzhou 510080China Department of Molecular Genetics and experimental Cardiology Masonic Medical Research LaboratoryUticaNY 13501USA

Wolff-Parkinson-White(WPW)syndrome is a congenital disorder of cardiac conduction system characterized by electrocardiographic preexcitation and episodes of paroxysmal supraventricular *** is caused by a cardiac developmental defect in the electrical insulation between the atria and the ventricles due to the presence of an accessory *** syndrome is a common cause of supraventricular tachycardia with benign ***,this clinical entity also predisposes patients to an increased risk of sudden cardiac death,especially in the setting of preexcited atrial *** syndrome is usually sporadic and of unknown etiology in most *** the past10years,a signifi cant heritable factor is increasingly *** cation of the genetic basis among patients with WPW syndrome has important implications for understanding the molecular mechanism of ventricular preexcitation and the development of therapeutic strategies for risk stratifi cation and *** goal of this review is to examine the previous studies on hereditary variants,as well as to outline potential future avenues toward defi ning the heritability of WPW syndrome.

关键词： Wolff-Parkinson-White syndrome ventricular preexcitation genetics

Arsenic Tolerance in Mesquite（Prosopis sp.）:Low Molecular Weight Thiols Synthesis and Glutathione Activity in Response to As（Ⅲ） and （Ⅴ）

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Arsenic Tolerance in Mesquite（Prosopis sp.）:Low Molecular ...

A Formal System for the Illocutionary Force and Its Applications in Al

第三十五届国际光谱会议

作者： N.S.Mokgalaka-Matlala e.Flores-Tavizón H.Castillo-miche J.R.Peralta-Videa J.L.Gardea-Torresdey R.I.Mc Crindle Tshwane University of Technology Department of Chemistry Arcadia CampusPrivate Bag X680Pretoria0001South Africa Department of ChemistryUniversity of Texas at El Paso Department of Chemistry University of Texas at el Paso Tshwane University of Technology Department of Chemistry Arcadia CampusPrivate Bag X680Pretoria0001South Africa Department of ChemistryUniversity of Texas at El Paso Environmental Science and Engineering PhD Program500W University Ave.El PasoTX 79968-0513USA Department of Chemistry University of Texas at el Paso Department of Chemistry University of Texas at el Paso Tshwane University of Technology Department of Chemistry Arcadia CampusPrivate Bag X680Pretoria0001South Africa

＜正＞This study reports the tolerance of arsenic induced-stress by mesquite （Prosopis sp.） *** response of mesquite towards the toxicity effects imposed by As were studied through evaluation of plant growth,nutrients content,synthesis of acid-soluble low molecular weight thiols （LMWTs） and glutathione S-transferase （GST） *** seeds of mesquite were germinated and grown in a hydroponics *** 3 days of growth in a nutrient solution,the plants were transferred to nutrient solution

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Social Sciences in China 2003年第3期24卷 142-148页

作者： Cai Shushan, phd, Professor of Philosophy,

本文以John R.塞尔和D.范德维克关于语用逻辑的研究工作为基础,构造了命题的语用逻辑的形式公理系统PF,证明了PF的三类定理:关于语用行为的定理、关于条件的语用行为的定理以及关于语用力量的定理。作者还构造了PF的语义模型,给出了系... 详细信息

本文以John R.塞尔和D.范德维克关于语用逻辑的研究工作为基础,构造了命题的语用逻辑的形式公理系统PF,证明了PF的三类定理:关于语用行为的定理、关于条件的语用行为的定理以及关于语用力量的定理。作者还构造了PF的语义模型,给出了系统的语义解释,并证明了系统的可靠性、一致性和完全性。本文以语用逻辑的方法,分析了人工智能语言PROLOC的语法和语义,以及语用逻辑在学习策略中的应用。最后讨论了语用逻辑的形式化和语言逻辑在认知科学中的应用等问题。作者的工作是继乔姆斯基的形式语法学、蒙太格的形式语义学之后,对语用学的基础理论语用逻辑的形式化研究所做的尝试。

关键词：语用逻辑语用行为形式公理系统学习策略定理人工智能语言语用力量语义模型语义解释可靠性

“eye Science” in 2011

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eye Science 2011年第1期26卷 1-2页

作者： Jian Ge MD phd Zhongshan Ophthalmic Center Guangzhou

2011 is an opportune time for Yanke Xuebao (eye Science) to launch its bilingual edition as a platform for cooperation between Chinese and international vision *** yearly research output of Chinese investigators in all fields of science, but particularly biomedicine, has been growing recently by leaps and *** an example, the American Journal of Ophthalmology (AJO), one of the most prestigious clinical journals in our field,received more submissions from east Asian authors (Japan, China and Korea alone)than they did from the United States in *** investigators ranked third on the list, climbing rapidly, only after the US and *** vision research centers in China, such as Zhongshan Ophthalmic Center, where eye Science is published, now rank alongside Moorfields and Johns Hopkins as among the most prolific institutions in the world, measured by articles appearing annually in peer-reviewed SCI journals.

关键词：《眼科学报:英文版》期刊编辑部 2011年