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Steatosis and steatohepatitis in postmortem material from Northwestern Greece

World Journal of Gastroenterology 2010年第31期16卷 3944-3949页

作者： Christos D Zois Gerasimos H Baltayiannis Anna Bekiari Anna Goussia Peter Karayiannis michalis Doukas Demetrios Demopoulos Antigoni Mitsellou Theodoros Vougiouklakis Vasiliki Mitsi Epameinondas V Tsianos 1st Department of Internal Medicine and Hepato-Gastroenterology Unit Medical SchoolUniversity of Ioannina Laboratory of Pathology Medical SchoolUniversity Hospital of Ioannina Department of Medicine Hepatology Sec-tionDivision of MedicineImperial College LondonVariety Wing Floor DSt.Mary's Campus Norfolk Place London W2 1PGLondonUnited Kingdom Department of Forensic Medicine and Toxicology Medical SchoolUniversity of Ioannina

AIM: To determine the prevalence of steatosis and steatohepatitis in a series of autopsies in Northwestern Greece. METHODS: Liver biopsy material from a total of 600 autopsies performed over a period of 2 years (2006-2008) to def ine the cause of death was subjected to histological examination. Patient demographic data were also collected. Tissue sections were stained with different dyes for the evaluation of liver architecture, degree of fibrosis and other pathological conditions when necessary. RESULTS: Satisfactory tissue samples for histological evaluation were available in 498 cases (341 male, 157 female) with a mean age of 64.51 ± 17.78 years. In total, 144 (28.9%) had normal liver histology, 156 (31.3%) had evidence of steatosis, and 198 (39.8%) had typical histological findings of steatohepatitis. The most common causes of death were ischemic heart disease with or without myocardial infarction (43.4%), and traffic accidents (13.4%). CONCLUSION: A high prevalence of steatosis and steatohepatitis was detected in postmortem biopsies from Northwestern Greece. Since both diseases can have serious clinical consequences, they should be considered as an important threat to the health of the general population in Greece.

关键词： Fatty liver Non-alcoholic liver disease Steatosis Steatohepatitis Autopsy

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Ultrahigh-density spin-polarized hydrogen isotopes from the photodissociation of hydrogen halides:new applications for laser-ion acceleration,magnetometry,and polarized nuclear fusion

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Light(Science & Applications) 2021年第3期10卷 341-351页

作者： Alexandras K.Spiliotis michalis Xygkis Michail E.Koutrakis Konstantinos Tazes Gregoris K Boulogiannis Chrysovalantis S.Kannis Georgios E.Katsoprinakis Dimitrios Sofikitis T.Peter Rakitzis Foundation for Research and Technology Hellas Institute of Electronic Structure and LaserN.Plastira 100HeraklionCrete GR-71110Greece University of Crete Department of PhysicsHerakleioGreece Department of Physics Atom ic and Molecular Physics LaboratoryUniversity of loanninaUniversity Campusloannina GR-45110Greece

Recently,our group produced spin-polarized hydrogen(SPH)atoms at densities of at least 10^(19)cm^(-3)from the photodissociation of hydrogen halide molecules with circularly polarized UV light and measured them via magnetization-quantum beats with a pickup *** densities are approximately 7 orders of magnitude higher than those produced using conventional methods,opening up new fields of application,such as ultrafast magnetometry,the production of polarized MeV and GeV particle beams,such as electron beams with intensities approximately 10^(4)higher than current sources,and the study of polarized nuclear fusion,for which the reaction cross sections of D-T and D-(3)^He reactions are expected to increase by 50%for fully polarized nuclear *** review the production,detection,depolarization mechanisms,and potential applications of high-density SPH.

关键词： polarized approximate magneto

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Intelligent Decisions Modeling for Energy Saving in Lifts:An Application for Kleemann Hellas Elevators

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Energy and Power Engineering 2013年第3期5卷 236-244页

作者： Vasilios Zarikas Nick Papanikolaou michalis Loupis Nick Spyropoulos Department of Electrical Engineering Informatics Division ATEI Lamias Lamia Greece Department of Electrical Engineering Power Electronics Division ATEI Lamias Lamia Greece Department of Electrical Engineering Theory Division Academic Institute of Technology of Lamia ATEI Lamias Lamia Greece Research and Development Division Kleeman Hellas Kilkis Greece

The present work proposes a methodological approach for modeling decisions regarding energy reduction in an elevator. This is achieved with the integration of existing as well as acquired knowledge, in a decision module implemented in the electronics of an elevator. So far, elevators do not exploit information regarding their recent usage. In the developed system decisions are driven based on information arising from monitoring the use of the elevator. Monitoring provides various records of usage which consequently are used to predict elevator’s future usage and to adapt accordingly its functioning. Till now, there are only elevators that encompass in their electronics algorithms with if then rules in order to control elevator’s functioning. However, these if then rules are based only on good practice knowledge of similar elevators installed in similar buildings. Even this knowledge which unavoidably is associated with uncertainty is not encoded in a mathematically consisted way in the algorithms. The design, the implementation and a first pilot evaluation study of an elevator’s intelligent decision module are presented. The study concludes that the presented application sufficiently reduces energy consumption through properly controlled functioning.

关键词： Elevators Energy Consumption Reduction Energy Engineering Applied Bayesian Networks Applied Decision Networks Applied Influence Diagrams Applied Intelligent Decisions Fuzzy Rules

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Update on diagnosis and management of cuboid fractures

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World Journal of Orthopedics 2019年第2期10卷 71-80页

作者： Antonios G Angoules Nikolaos A Angoules michalis Georgoudis Stylianos Kapetanakis Orthopaedic Department Athens Medical Center School of Physiotherapy AMC Metropolitan College Spine Department and Deformities Interbalkan European Medical Center

Cuboid fractures due to the particular bone anatomy and its protected location in the midfoot are rare, and they are usually associated with complex injuries of the foot. Clinical examination to diagnose these fractures should be detailed and the differential diagnosis, especially in the case of vague symptoms, should include the exclusion of all lateral foot pain causes. Conventional radiographs do not always reveal occult fractures, which can be under diagnosed especially in children. In this case, further investigation including magnetic resonance imaging or scintigraphy may be required. The treatment of these injuries depends on the particular fracture characteristics. Non-displaced isolated fractures of the cuboid bone can be effectively treated conservatively by immobilization and by avoiding weight bearing on the injured leg. In the case of shortening of the lateral column> 3 mm or articular displacement > 1 mm, surgical management of the fracture is mandatory in order to avoid negative biomechanical and functional consequences for the foot and adverse effects such as arthritis and stiffness as well as painful gait. In this review, an update on diagnosis and management of cuboid fractures is presented.

关键词： Cuboid Fracture Diagnosis Treatment Surgery

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Diffusive modelling of glioma evolution: a review

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Journal of Biomedical Science and Engineering 2010年第5期3卷 501-508页

作者： Alexandros Roniotis Kostas Marias Vangelis Sakkalis michalis Zervakis 不详

Gliomas, the most aggressive form of brain cancer, are known for their widespread invasion into the tissue near the tumor lesion. Exponential models, which have been widely used in other types of cancers, cannot be used for the simulation of tumor growth, due to the diffusive behavior of glioma. Diffusive models that have been proposed in the last two decades seem to better approximate the expansion of gliomas. This paper covers the history of glioma diffusive modelling, starting from the simplified initial model in 90s and describing how this have been enriched to take into account heterogenous brain tissue, anisotropic migration of glioma cells and adjustable proliferation rates. Especially, adjustable proliferation rates are very important for modelling therapy plans and personalising therapy to different patients.

关键词： Glioma Brain Tumor Diffusive Models Proliferation Invasion

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Huge Intravaginal Pedunculated Fibroid Embolization and Resectoscopy—A Case Report and Review of Literature

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Surgical Science 2019年第7期10卷 222-228页

作者： Hirides Petros Karygiannis michalis Tsoumbis Athanasios Hirides Savvas Athens Medical Center Marousi Greece

Background: Submucosal fibroids account for approximately 15 - 20 percent of total fibroids. Rarely, they prolapse. Common size is 2 - 6 cm, because larger fibroids are unlikely to fit through the cervix. Larger fibroids are associated with significant bleeding and pose a surgical challenge. Case Presentation: We present a 38-year-old woman nulliparous with an intravaginal pedunculated fibroid, 12 cm in diameter. She presented with metrorrhagia and an intense malodorous vaginal discharge, irresponsive to oral therapy. The patient had a history of resectoscopic fibroid enucleation, 7 months earlier, followed by insertion of an (intra-uterine device) IUD. There was no uterine prolapse. Management involved bilateral uterine artery embolization, followed by hysteroscopic excision with rigid resectoscope. The fibroid was “delivered” transvaginally intact. The uterus was preserved. The IUD was partly buried within the mass. Blood loss was negligible. Patient recovery was quick and uneventful. At 6-months follow up, pelvic anatomy has been restored. Conclusion: Large pedunculated fibroids are very rare. Embolization of uterine arteries has proven a valuable tool in challenging gynecologic operations. In our case, not only it prevented massive bleeding during excision, but also allowed a fertility-sparing minimally invasive management.

关键词： Pedunculated Fibroid Prolapsed Leiomyoma Uterine Artery Embolization Hysteroscopy

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Exercise-mediated adaptations in vascular function and structure:Beneficial effects in coronary artery disease

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World Journal of Cardiology 2021年第9期13卷 399-415页

作者： Xenofon M Sakellariou Michail I Papafaklis Eleni M Domouzoglou Christos S Katsouras Lampros K michalis Katerina K Naka Michailideion Cardiac Centre University of IoanninaIoannina 45100EpirusGreece 2nd Department of Cardiology University Hospital of IoanninaIoannina 45100EpirusGreece Department of Pediatrics University Hospital of IoanninaIoannina 45100EpirusGreece

Exercise exerts direct effects on the vasculature via the impact of hemodynamic forces on the endothelium,thereby leading to functional and structural adaptations that lower cardiovascular *** patterns of blood flow and endothelial shear stress during exercise lead to atheroprotective hemodynamic stimuli on the endothelium and contribute to adaptations in vascular function and *** structural adaptations observed in arterial lumen dimensions after prolonged exercise supplant the need for acute functional vasodilatation in case of an increase in endothelial shear stress due to repeated exercise *** contrast,wall thickness is affected by rather systemic factors,such as transmural pressure modulated during exercise by generalized changes in blood *** mechanisms have been proposed to explain the exercise-induced benefits in patients with coronary artery disease(CAD).They include decreased progression of coronary plaques in CAD,recruitment of collaterals,enhanced blood rheological properties,improvement of vascular smooth muscle cell and endothelial function,and coronary blood *** review describes how exercise via alterations in hemodynamic factors influences vascular function and structure which contributes to cardiovascular risk reduction,and highlights which mechanisms are involved in the positive effects of exercise on CAD.

关键词： Exercise Endothelium Flow-mediated dilation Endothelial shear stress Coronary artery disease Hemodynamics

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笼中之鸟重放歌喉

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英语学习 2015年第2期 64-69页

作者： Maya angelou 蒋素华

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Bochdaleck's hernia complicating pregnancy: Case report

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World Journal of Gastroenterology 2006年第15期12卷 2469-2471页

作者： Nikolaos Barbetakis Andreas Efstathiou michalis Vassiliadis Theocharis Xenikakis Ioannis Fessatidis Department of Cardiothoracic Surgery Geniki Kliniki-Euromedica Paraliaki Ave and Gravias 2ThessalonikiGreece

膈疝复杂化怀孕是稀罕的并且导致高死亡率，特别地如果早外科的干预没被承担。我们报导在 23 wk 的怀孕期介绍的一个女人通过隔膜(Bochdalek 的脱肠) 的一个左后外侧缺点由于内脏的下狱与呼吸衰竭和肠阻塞的症状被同意进入的一个案例。... 详细信息

膈疝复杂化怀孕是稀罕的并且导致高死亡率，特别地如果早外科的干预没被承担。我们报导在 23 wk 的怀孕期介绍的一个女人通过隔膜(Bochdalek 的脱肠) 的一个左后外侧缺点由于内脏的下狱与呼吸衰竭和肠阻塞的症状被同意进入的一个案例。外科(左胸腹切口) 表明了到结束吻合的结束与肠连续性的重建导致了大肠的深奥部分的部分切除术的 herniated 内脏的压迫性膨胀不全，纵隔移动，窒息和坏疽。大网膜是部分坏死的要求切除术。横隔膜的缺点与间断缝术被关上。手术后的时期是不复杂的。怀孕被允许继续直到 39 wk 在时间，选任的恺撒的交货被执行的怀孕期。征兆的母亲的膈疝在怀孕期间是一种外科的紧急情况并且要求怀疑的一个高索引，这被结束。

关键词：疝气怀孕隔膜妊娠期

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生活的一课(有删节)

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疯狂英语（阅读版） 2007年第10期 56-61页

作者： Maya angelou 一茗

本来是给自己画了一个圈,在只有自己的圈里体验着自己的酸甜苦辣。突然有一天,这个圈被打开了一个口子,你和另一个圈有了交集,你很荣幸地被邀请进入其中,去分享他或她的欢乐与忧虑。于是,原本孤独甚至干涸的心,顿时找到了从未有过的兴... 详细信息

本来是给自己画了一个圈,在只有自己的圈里体验着自己的酸甜苦辣。突然有一天,这个圈被打开了一个口子,你和另一个圈有了交集,你很荣幸地被邀请进入其中,去分享他或她的欢乐与忧虑。于是,原本孤独甚至干涸的心,顿时找到了从未有过的兴奋和欣喜——一份难得的尊重和信赖。这是多么重要啊!他人的爱和信赖会使人变得自信,并重新找到对自我的认同感。天真无邪的孩子尤其如此。当爱和信赖充满心间,生活就变得不再苍白!

关键词：查尔斯·狄更斯玛格丽特生活贝奥武甫长篇小说英国法国革命代表作声音分享

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