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Minimizing the risk of small-for-size syndrome after liver surgery

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Hepatobiliary & Pancreatic Diseases International 2022年第2期21卷 113-133页

作者： michail Papamichail michail Pizanias NigelD Heaton Department of Hepato-Pancreato-Biliary Surgery Royal Blackburn HospitalBlackburn BB23HHUK Department of general Surgery Whittington HospitalLondon N195NFUK Department of Liver Transplant and Hepato-Pancreato-Biliary Surgery Institute of Liver StudiesKings Health Partners at King’s College Hospital NHS TrustLondon SE59RSUK

Background: Primary and secondary liver tumors are not always amenable to resection due to location and size. Inadequate future liver remnant(FLR) may prevent patients from having a curative resection or may result in increased postoperative morbidity and mortality from complications related to small-forsize syndrome(SFSS). Data sources: This comprehensive review analyzed the principles, mechanism and risk factors associated with SFSS and presented current available options in the evaluation of FLR when planning liver surgery. In addition, it provided a detailed description of specifc modalities that can be used before, during or after surgery, in order to optimize the conditions for a safe resection and minimize the risk of SFSS. Results: Several methods which aim to reduce tumor burden, preserve healthy liver parenchyma, induce hypertrophy of FLR or prevent postoperative complications help minimize the risk of SFSS. Conclusions: With those techniques the indications of radical treatment for patients with liver tumors have signifcantly expanded. The successful outcome depends on appropriate patient selection, the individualization and modifcation of interventions and the right timing of surgery.

关键词： Small-for-size syndrome Liver resection Future liver remnant

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Pre-processing for time domain image formation in SS-BSAR system

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Journal of Systems Engineering and Electronics 2012年第6期23卷 875-880页

作者： michail Antoniou Mikhail Cherniakov School of Electronic Electrical and Computer EngineeringUniversity of BirminghamBirmingham B15 2TTUK

A pre-processing procedure is designed for a space-surface bistatic synthetic aperture radar （SS-BSAR） system when a time domain image formation algorithm is employed. Three crucial technical issues relating to the procedure are fully discussed. Firstly, unlike image formation algorithms operating in the frequency domain, a time domain algorithm requires the accurate global navigation satellite system （gNSS） time and position. This paper proposes acquisition of this information using a time-and-spatial transfer with precise ephemeris and interpolation. Secondly, synchronization errors and compensation methods in SS-BSAR are analyzed. Finally, taking the non-ideal factors in the echo and the compatibility of image formation algorithms into account, a matched filter based on the minimum delay is constructed. Experimental result using real data suggest the pre-processing is functioning properly.

关键词： image formation space-surface bistatic syntheticaperture radar (SS-BSAR) global navigation satellite system(gNSS) synchronization range compression.

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Passive gNSS-based SAR imaging and opportunities using galileo E5 signals

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Science China(Information Sciences) 2015年第6期58卷 84-94页

作者： MA Hui ANTONIOU michail CHERNIAKOV Mikhail School of Electronic and Information Engineering Beihang University Electronic Electrical and Systems Engineering Department University of Birmingham

This paper investigates the feasibility of galileo navigation satellites as transmitters of opportunity in passive bistatic synthetic aperture radar(SAR) systems from the perspectives of signal processing and experiment program. Experimental images obtained using a single galileo channel, E5 a or E5 b, are presented and analyzed. The paper also puts forward the channel combination scheme to jointly process E5 a and E5 b channels, which brings up high-resolution possibilities for passive SAR technique. By employing the entire E5 band for imaging, the range resolution may be potentially increased by up to 5 times. Preliminary experimental results for this concept are demonstrated.

关键词： bistatic synthetic aperture radar(BSAR) gNSS-based SAR galileo E5 channel combination

Space-surface bistatic synthetic aperture radar with navigation satellite transmissions: a review

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Science China(Information Sciences) 2015年第6期58卷 5-24页

作者： ANTONIOU michail CHERNIAKOV Mikhail MA Hui Electronic Electrical and Systems Engineering Department University of Birmingham School of Electronic and Information Engineering Beihang University

This paper reviews the theory and practice of Space-Surface Bistatic Synthetic Aperture Radar(SS-BSAR) using navigation satellites as transmitters. In recent years, this innovative technology has reached a maturity stage which allows it to be considered for a wide range of applications. The paper covers the fundamental aspects of this technology as a radar system, such as the resolution, power budget and Point Spread Function(PSF) analysis, as well as its signal processing aspects and the state of the art in terms of advanced SAR techniques that it enables. Finally, the theoretical aspects of the paper may be directly transferred to the more generic SS-BSAR concept.

关键词： bistatic synthetic aperture radar gNSS-based SAR space-surface bistatic SAR coherent change detection multi-perspective imaging

gNSS-based BiSAR imaging using modified range migration algorithm

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Science China(Information Sciences) 2015年第8期58卷 144-156页

作者： ZENg Tao LIU FeiFeng ANTONIOU michail CHERNIAKOV Mikhail Beijing Key Laboratory of Embedded Real-time Information Processing Technology Beijing Institute of Technology School of Electronic Electrical and Systems Engineering University of Birmingham

This paper proposed a new focusing approach for the bistatic SAR systems with a gNSS(global Navigation Satellite System) satellite as the transmitter. Because of the long integration time the inherited curvature of the transmitter’s trajectory was adopted and the spatial variance of the equivalent velocity was derived under the principal of equivalent slant range model in the system signal model. The proposed focusing approach consists of two-step processing. Firstly, the general Doppler phase from constant velocity of the echo data is focused by modified Stolt mapping. Secondly, the residual nonlinear Doppler phase due to velocity variation is compensated by means of block-processing-based adaptive phase compensation to achieve large scene focusing. The simulation and experimental results validate the proposed algorithm in gNSS-based Bi SAR systems.

关键词： gNSS-based Bi SAR equivalent slant range model curvature of trajectory two-step processing modified Stolt mapping

Coexistence Between Massive MIMO and Radar Communications:Performance Analysis

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Journal of Communications and Information Networks 2023年第1期8卷 37-47页

作者： Mohamed Elfiatoure Hien Quoc Ngo michail Matthaiou Centre for Wireless Innovation(CWI) Queen’s University BelfastBelfast BT39DTUK

Frequency spectrum sharing between radar and communication systems has recently attracted substantial *** consider the coexistence between a massive multiple-input multiple-output(MIMO)downlink system and MIMO radar to enable the operation of these two systems with minimal mutual *** an asymptotic analysis,we show that by using more antennas at the base station(BS),we can improve the performance of massive MIMO,while keeping the interference to the radar system ***,if we use a large number of antennas at the BS and make the transmit power inversely proportional to the number of antennas,we can avoid the interference from the massive MIMO system to the radar system,with no compromise in the performance of the massive MIMO ***-form expressions for the probability of detection of the radar system and the downlink spectral efficiency of the massive MIMO system,are ***,we propose a power allocation scheme which selects the transmit powers at the MIMO radar and BS to maximize the probability of detection for the MIMO ***,the optimal power allocation can be determined in *** results provide valuable insights into the practical coexistence between massive MIMO and radar systems.

关键词： massive MIMO radar-communication coexistence spectrum sharing

Circular RNAs in Cardiovascular Diseases:Regulation and Therapeutic Applications

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Research 2023年第3期6卷 389-407页

作者： Lijun Wang gui-e Xu michail Spanos guoping Li Zhiyong Lei Joost P.g.Sluijter Junjie Xiao Cardiac Regeneration and Ageing Lab Institute of Geriatrics(Shanghai University)Affiliated Nantong Hospital of Shanghai University(The Sixth People’s Hospital of Nantong)School of MedicineShanghai UniversityNantong 226011China Institute of Cardiovascular Sciences Shanghai Engineering Research Center of Organ RepairSchool of Life ScienceShanghai UniversityShanghai 200444China Cardiovascular Division of the Massachusetts general Hospital and Harvard Medical School BostonMA 02114USA Department of Cardiology Laboratory of Experimental CardiologyUniversity Medical Center UtrechtUtrecht 3508GAThe Netherlands CDL Research University Medical Center UtrechtUtrecht 3584CXThe Netherlands Regenerative Medicine Center Circulatory Health LaboratoryUniversity Medical Center UtrechtUniversity UtrechtUtrecht 3508GAThe Netherlands

Cardiovascular disease is one of the leading causes of mortality *** studies have shown that circular RNAs(circRNAs)have emerged as important players in the prevention and treatment of cardiovascular *** are a class of endogenous noncoding RNAs that are generated by back-splicing and are involved in many pathophysiological *** this review,we outline the current research progress on the regulatory roles of circRNAs in cardiovascular ***,new technologies and methods available for identifying,validating,synthesizing,and analyzing circRNAs,as well as their applications in therapeutics,are highlighted ***,we summarize the increasing insights into the potential use of circRNAs as circulating diagnostic and prognostic ***,we discuss the prospects and challenges of circRNA therapeutic applications for cardiovascular disease therapy,with a particular focus on developing circRNA synthesis and engineering delivery systems.

关键词： cardiovascular prevention Cardiovascular

Origin and genomic characteristics of SARS-CoV-2 and its interaction with angiotensin converting enzyme type 2 receptors, focusing on the gastrointestinal tract

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World Journal of gastroenterology 2020年第41期26卷 6335-6345页

作者： michail galanopoulos Aris Doukatas Maria gazouli Department of gastroenterology 401 General Military Hospital of AthensAthens 11525AttikiGreece Medical Office of Hellenic Army general Staff 401 General Military Hospital of AthensAthens 11525AttikiGreece Laboratory of Biology School of MedicineNational and Kapodistrian University of AthensAthens 11527AttikiGreece

The emergence of coronavirus disease-2019 induced by a newly identified bcoronavirus, namely severe acute respiratory syndrome coronavirus 2(SARSCoV-2) has constituted a public health emergency. Even though it was considered a zoonotic disease, the virus has also spread among humans via respiratory secretions. The expression and distribution of angiotensin converting enzyme type 2(ACE2) in various human organs might also show other possible infection routes. High ACE2 ribonucleic acid expression has been identified in the gastrointestinal tract(gI) indicating its importance as a possible infection pathway of SARS-CoV-2. ACE2 induces viral entry into the host and most importantly has been found to be associated with the function of the gut. Its deficiency has been implicated in several pathologies such as colorectal inflammation. The renin-angiotensin system(RAS) is an essential regulatory cascade operating both at a local tissue level and at the systemic or circulatory level. The RAS may be important in the pathogenesis of chronic liver disease and is associated with the up-regulation of ACE2. Thus, the aim of this review is firstly, the analysis of some important general and genome characteristics of SARS-CoV-2 and secondly, and most importantly, to focus on the utility of ACE2 receptors in both SARS-CoV-2 replication and pathogenesis, especially in the gI tract.

关键词： SARS-CoV-2 COVID-19 gastrointestinal tract Angiotensin converting enzyme type 2 Angiotensin converting enzyme type 2 receptor Renin-angiotensin system Angiotensin converting enzyme

Unraveling the mechanisms of a giant coronary sinus

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Journal of geriatric Cardiology 2023年第6期20卷 483-484页

作者： michail Kyrtsopoulos Apostolos galatas Anastasios Kartas Cardiology Department AHEPA University HospitalAristotle University of ThessalonikiThessalonikiGreece

The coronary sinus(CS)is a tubular venous structure in the left atrioventricular groove that drains around 55% of the deoxygenated coronary arterial blood supply into the right atrium.[1,2]The CS,predominantly a small structure,can be significantly dilated leading to a condition known as giant *** CS is a clinically important but rare echocardiographic finding,which can be caused by a variety of factors.

关键词： coronary sinus arterial

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