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Maximizing biomass utilization: An integrated strategy for coproducing multiple chemicals

journal of Energy Chemistry 2025年第1期100卷 180-191页

作者： Byeongchan Ahn Sua jo jonggeol Na j.jay Liu Young-ju Kim Wangyun Won Department of Chemical and Biological Engineering Korea University Department of Chemical Engineering (Integrated process) Kyung Hee University Department of Chemical Engineering and Materials Science Ewha Womans University Department of Chemical Engineering Pukyong National University Resources Engineering Plant Research Department Korea Institute of Geoscience and Mineral Resources

Lignocellulosic biomass is one of the viable solutions to alleviate the global warming. However, the limited utilization of biomass majorly focused on cellulose and hemicellulose restricts the economic and environmental feasibilities. To cope with this issue, we proposed an integrated process of co-producing 1,6-hexanediol（1,6-HDO） with tetrahydrofuran and adipic acid from biomass, referred to as Strategy A. To compare the impacts of lignin upgrading and feedstock, Strategy B, which co-produces tetrahydrofuran alone, and Strategy C, which is the traditional route to produce 1,6-HDO from fossil fuels, were used. Heat networks are also designed to reduce operating costs and indirect carbon emissions due to energy consumption, saving 87% and 83% of the heat and cooling requirements, respectively, in Strategy A. The market competitiveness of Strategy A was evaluated by determining the minimum selling price through techno-economic analysis, and sustainability was thoroughly investigated by quantifying the environmental impacts through both midpoint and endpoint life-cycle assessments（LCAs）.Strategy A was found to be the most favorable both economically（USRDSCHARDOLLAR3,402/ton） and environmentally（-26.9 kg CO2eq.）. This indicates that lignin valorization is not only economically but also environmentally preferred. Finally, changes in economic and environmental feasibilities depending on economic, process, and environmental parameters were investigated using sensitivity and uncertainty analyses. The results of these analyses provide valuable insight into bio-based chemical production.

关键词： Biorefinery Carbon mitigation Climate change Global warming Lignin utilization Bioeconomy

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Simple Algorithms for Network Visualization:A Tutorial

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Tsinghua Science and Technology 2012年第4期17卷 383-398页

作者： michael j.McGuffin Department of Software and IT Engineering cole de technologie suprieureMontral H3C 1K3Canada

The graph drawing and information visualization communities have developed many sophisticated techniques for visualizing network data, often involving complicated algorithms that are difficult for the uninitiated to learn. This article is intended for beginners who are interested in programming their own network visualizations, or for those curious about some of the basic mechanics of graph visualization. Four easy-to-program network layout techniques are discussed, with details given for implementing each one： force-directed node-link diagrams, arc diagrams, adjacency matrices, and circular layouts. A java applet demonstrating these layouts, with open source code, is available at http：//***/research/simpleNetVis/. The end of this article also briefly surveys research topics in graph visualization, pointing readers to references for further reading.

关键词： network visualization graph visualization graph drawing node-link diagram force-directed layout arcdiagram adjacency matrix circular layout tutorial

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How to make the "jump" on understanding the importance of the intrinsic foot muscles for propulsion

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journal of Sport and Health Science 2023年第5期12卷 648-650页

作者： michael j.Asmussen Department of Biology Faculty of Science&TechnologyMount Royal UniversityCalgaryAB T3E 6K6Canada

In this issue of the journal of Sport and Health Science,Smith and colleagues1addressed a unique aspect of human locomotion;they evaluated the effects of the intrinsic foot musculature on the mechanical properties and energetic function of the human *** performing a controlled jumping experiment to mimic components of human locomotion.

关键词： intrinsic muscles propulsion

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Universal Hyperthermal Model for Mass Extinctions

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journal of Earth Science 2024年第2期35卷 704-707页

作者： michael j.Benton Paleobiology Research Group School of Earth SciencesUniversity of BristolLife Sciences BuildingTyndall AvenueBristolBS81TQUK

INTRODUCTION Earth scientists have long sought universal features of past extinction *** can be argued that each past extinction event was a singularity,caused by combinations of circumstances that are unique in each case,and therefore that the search for common causes is ***,a key feature of the uniformitarian approach to geology is that past processes are the same as modern-day processes and,with that in mind,earth scientists are keen to use their knowledge to contribute some understanding to the study of the present and future climate crisis.

关键词： extinction singularity Extinction

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Understanding Performance for Two 802.11 Competing Flows

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journal of Computer Science & Technology 2008年第3期23卷 365-376页

作者： michael j.Feeley Brendan Cully Sharath j.George Department of Computer Science University of British ColumbiaVanconverCanada

It is well known that 802.11 suffers from both inefficiency and unfairness in the face of competition and interference. This paper provides a detailed analysis of the impact of topology and traffic type on network performance when two flows compete with each other for airspace. We consider both TCP and UDP flows and a comprehensive set of node topologies. We vary these topologies to consider all combinations of the following four node-to-node interactions：（1） nodes unable to read or sense each other, （2） nodes able to sense each other but not able to read each other＇s packets and nodes able to communicate with （3） weak and with （4） strong signal. We evaluate all possible cases through simulation and show that the cases can be reduced to 9 UDP and 10 TCP 802.11g models with similar efficiency/fairness characteristics. We also validate our simulation results with extensive experiments conducted in a laboratory testbed. These more detailed models improve on previous work such as hidden-/exposed-terminal categorization and are thus better suited as a basis for adaptive techniques to improve performance in 802.11 multi-hop WLAN or Mesh Networks.

关键词： 802.11 wireless unfairness two-flow competition network topology

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Distributed Control of Chemical Process Networks

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International journal of Automation and computing 2015年第4期12卷 368-381页

作者： michael j.Tippett jie Bao School of Chemical Engineering The University of New South Wales

In this paper,we present a review of the current literature on distributed(or partially decentralized) control of chemical process *** particular,we focus on recent developments in distributed model predictive control,in the context of the specific challenges faced in the control of chemical process *** paper is concluded with some open problems and some possible future research directions in the area.

关键词： Distributed process control chemical process systems process networks plantwide control distributed model predictive control.

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Current strategies for the treatment of inborn errors of metabolism

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journal of Genetics and Genomics 2018年第2期45卷 61-70页

作者： michael j.Gambello Hong Li Department of Human Genetics Emory University School of Medicine

Inborn errors of metabolism（IEMs） are a large group of inherited disorders characterized by disruption of metabolic pathways due to deficient enzymes, cofactors, or transporters. The rapid advances in the understanding of the molecular pathophysiology of many IEMs, have led to significant progress in the development of many new treatments. The institution and continued expansion of newborn screening provide the opportunity for early treatment, leading to reduced morbidity and mortality. This review provides an overview of the diverse therapeutic approaches and recent advances in the treatment of IEMs that focus on the basic principles of reducing substrate accumulation, replacing or enhancing absent or reduced enzyme or cofactor, and supplementing product deficiency. In addition, the challenges and obstacles of current treatment modalities and future treatment perspectives are reviewed and discussed.

关键词： Inborn errors of metabolism Treatment Dietary therapy Enzyme replacement therapy Substrate reduction therapy Pharmacological chaperone therapy

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Floor dust erosion during early stages of coal dust explosion development

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International journal of Mining Science and Technology 2019年第6期29卷 825-830页

作者： Marcia L.Harris michael j.Sapko Center for Disease Control and Prevention (CDC) National Institute for Occupational Safety and Health (NIOSH) Pittsburgh Mining Research Division (PMRD)

An ignition of methane and air can generate enough air flow to raise mixtures of combustible coal and rock *** expanding high temperature combustion products ignite the suspended dust mixture and will continue to propagate following the available combustible fuel *** the concentration of the dispersed rock dust is sufficient,the flame will stop ***-scale explosion tests were conducted within the National Institute for Occupational Safety and Health(NIOSH)Lake Lynn Experimental Mine(LLEM)to measure the dynamic pressure history and the post-explosion dust scour *** aim of this effort is to provide quantitative data on depth of dust removal during the early stages of explosion development and its relationship to the depth of floor dust collected for assessing the incombustible content most likely to participate in the combustion *** experimental work on dust removal on is not only important for coal mine safety but also for industrial dust explosions.

关键词： Underground Coal dust Explosion Dust sampling

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Generalized stacking fault energy surface mismatch and dislocation transformation

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npj Computational Materials 2021年第1期7卷 1863-1870页

作者： Longsheng Feng michael j.Mills Yunzhi Wang Department of Materials Science and Engineering The Ohio State University2041 College RoadColumbusOH 43210USA

Even though the fundamental rules governing dislocation activities have been well established in the past century,we report a phenomenon,dislocation transformation,governed by the generalized-stacking-fault energy surface mismatch(GSF mismatch for short)between two co-existing *** carrying out ab-initio-informed microscopic phase-field simulations,we demonstrate that the GSF mismatch between a high symmetry matrix phase and a low symmetry precipitate phase can transform an array of identical full dislocations in the matrix into an array of two different types of full dislocations when they shear through the *** precipitates serve as a passive Shockley partial source,creating new Shockley partial dislocations that are neither the ones from the dissociation of the full *** phenomenon enriches our fundamental understanding of partial dislocation nucleation and dislocation-precipitate interactions,offering additional opportunities to tailor work-hardening and twinning processes in alloys strengthened by low-symmetry precipitate phases.

关键词： transformation dislocation mismatch

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CHO cell cytotoxicity and genotoxicity analyses of disinfection by-products： An updated review

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journal of Environmental Sciences 2017年第8期29卷 64-76页

作者： Elizabeth D.Wagner michael j.Plewa Safe Global Water Institute University of Illinois at Urbana-Champaign 1101 W Peabody Dr. Urbana IL 61801 United States Department of Crop Sciences University of Illinois at Urbana-Champaign 1101 W Peabody Dr. Urbana IL 61801 United States

The disinfection of drinking water is an important public health service that generates high quality, safe and palatable tap water. The disinfection of drinking water to reduce waterborne disease was an outstanding public health achievement of the 20 th *** unintended consequence is the reaction of disinfectants with natural organic matter,anthropogenic contaminants and bromide/iodide to form disinfection by-products（DBPs）.A large number of DBPs are cytotoxic, neurotoxic, mutagenic, genotoxic, carcinogenic and teratogenic. Epidemiological studies demonstrated low but significant associations between disinfected drinking water and adverse health effects. The distribution of DBPs in disinfected waters has been well defined by advances in high precision analytical chemistry. Progress in the analytical biology and toxicology of DBPs has been *** objective of this review was to provide a detailed presentation of the methodology for the quantitative, comparative analyses on the induction of cytotoxicity and genotoxicity of103 DBPs using an identical analytical biological platform and endpoints. A single Chinese hamster ovary cell line was employed in the assays. The data presented are derived from papers published in the literature as well as additional new data and represent the largest direct quantitative comparison on the toxic potency of both regulated and emerging *** data may form the foundation of novel research to define the major forcing agents of DBP-mediated toxicity in disinfected water and may play an important role in achieving the goal of making safe drinking water better.

关键词： DBPs Mammalian cell cytotoxicity Mammalian cell genotoxicity

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